• KSCE Journal of Civil and Environmental Engineering Research
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• v.3 no.3
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• pp.27-37
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• 1983

A method of dynamic analysis is developed for torsional free vibrations of elliptical-box girder type or stiffening truss system suspension bridge. In this study, the method based on a finite element technique using a digital computer, is illustrated by two numerical examples, the Namhae Bridge which is located in Kyungsang nam-do opened on June, 1973, and the Mt. Chunma Bridge is simple span pedestrian's suspension bridge with lateral bracing system in Mt. Chunma, Kyungki-do, are used. In general, dynamic modes of complex suspension bridges are three-dimensional in form, i.e., coupling between vertical and torsional motions. However, introduced that amplitudes of oscillation are infinitesimal for coincidence with the purpose of it's use, thereupon, the torsional vibration analyses are treated without coupling terms. A sufficient number of natural frequencies and mode shapes for torsional free vibration are presented in this paper. In the case of Mt. Chunma Bridge, the natural frequencies and periods are computed with and without reinforcement, respectively, and compared their discrepancies. The influence of the auxiliary reinforcing cables is prevailing in the first few modes, namely, 1st and 2nd in symmetric and 1st, 2nd and 3rd in antisymmetric vibration, and conspicuous in the symmetric compared with the antisymmetric motion, but in the higher modes, this kind of simple accessory elucidates rether converse effects. In the Namhae Bridge, the results are compared with the Manual's obtained by wind tunnel test. It reveals commendable agreement.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.30 no.2
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• pp.69-83
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• 2018

The South China Sea (SCS) is a typical marginal sea characterized with the deep basin, shelf break, shallow shelf, many straits, and complex bathymetry. This study investigated the tidal characteristics and propagation, and reproduced typhoon-induced storm surge in this region using the regional real-time tide-surge model, which was based on the unstructured grid, resolving in detail the region of interest and forced by tide at the open boundary and by wind and air pressure at the surface. Typhoon Haiyan, which occurred in 2013 and caused great damage in the Philippines, was chosen as a case study to simulate typhoon's impact. Amplitudes and phases of four major constituents were reproduced reasonably in general, and the tidal distributions of four constituents were similar to the previous studies. The modelled tide seemed to be within the acceptable levels, considering it was difficult to reproduce the tide in this region based on the previous studies. The free oscillation experiment results described well the feature of tide that the diurnal tide is prevailing in the SCS. The tidal residual current and total energy dissipation were discussed to understand the tidal and sedimentary environments. The storm-surge caused by typhoon Haiyan was reasonably simulated using this modeling system. This study established the regional real-time barotropic tide/water level prediction system for the South China Sea including the seas around the Philippines through the validation of the model and the understanding of tidal characteristics.

• Fisheries and Aquatic Sciences
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• v.27 no.3
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• pp.145-158
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• 2024

Life history characteristics, habitat landscape, and historical events are believed to have shaped the patterns of genetic variation in many taxa. The bony lip barb, Osteohilus vittatus, represent a potamodromous fish that complete all life cycle in freshwater and is widely distributed in Southeast Asia. It usually lives in small rivers and other freshwater habitats, and movement between habitats for either food or reproduction has been typical. These life history characteristics may promote gene flow, leading to less structured populations. However, many freshwater habitats are fragmented, which restricts gene flow. We investigate how this interplay has shaped patterns of genetic variation and phylogeographic structure within this species in the Sundaland, a biodiversity hotspot with a complex geological history, using mitochondrial cytochrome oxidase I (mtCOI) as a genetic marker. Forty-six mtCOI sequences of 506 bp long were collected from ten localities, eight geographically isolated and two connected. The sequences were used for population genetic and phylogeographic analyses. Our results showed a low genetic diversity within populations but high between populations. There was a deep phylogeographic structure among geographically isolated populations but a lack of such structure in the connected habitats. Among geographically isolated populations, sequence divergence was revealed, ranging from 1.8% between Java and Sumatra populations to 12.2% between Malaysia and Vietnam. An indication of structuring was also observed among localities that are geographically closer but without connectivity. We conclude that despite high dispersal capacity, the joint effects of historical events, long-term geographic isolation associated with sea level oscillation during the Pleistocene, and restricted gene flow related to lack of habitat connectivity have shaped the phylogeographic structure within the O. vittatus over the Sundaland.

• Analytical Science and Technology
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• v.13 no.4
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• pp.494-503
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• 2000

A 21-residue peptide corresponding to amino acids 84-104 of $p16^{INK4A}$, the tumor suppressor, has been synthesized and its structure was studied by Circular Dichroism, $^1H$ NMR spectroscopy and molecular modeling. A p16-derived peptide (84-104 amino acids) forming stable complex with CDK4 and CDK6 inhibits the ability of CDK4/6 to phosphorylate pRb in vitro, and blocks cell-cycle progression through G1/S phase as shown in the function of the full-length p16. Its NMR spectral data including NOEs, $^3J_{NH-H{\alpha}}$ coupling constants, $C_{\alpha}H$ chemical shift, the average amplitude of amide chemical shift oscillation and temperature coefficients indicate that the secondary structure of a p16-derived peptide is similar to that of the same region of full-length p16, which consists of helix-turn-helix structure. The 3-D distance geometry structure based on NOE-hased distance and torsion angle restraints is characterized by ${\gamma}$-turn conformation between residues $Gly^{89}-Leu^{91}$(${\varphi}_{i+1}=-79.8^{\circ}$, ${\varphi}_{i+1}=60.2^{\circ}$) as evidenced in a single crystal structure for the corresponding region of p18 or p19, but is undefined at both the N and C termini. This compact and rigid ${\gamma}$-turn region is considered to stabilize the structure of p16-derived peptide and serve as a site recognizing cyelin dependent kinase, and this well-defined ${\gamma}$-turn structure could be utilized for the design of anti-cancer drug candidates.