• 제목/요약/키워드: complex mixture analysis

검색결과 112건 처리시간 0.023초

A Study on Characteristics of Lincomycin Degradation by Optimized TiO2/HAP/Ge Composite using Mixture Analysis (혼합물분석을 통해 최적화된 TiO2/HAP/Ge 촉매를 이용한 Lincomycin 제거특성 연구)

  • Kim, Dongwoo;Chang, Soonwoong
    • Journal of the Korean GEO-environmental Society
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    • 제15권1호
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    • pp.63-68
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    • 2014
  • In this study, it was found that determined the photocatalytic degradation of antibiotics (lincomycin, LM) with various catalyst composite of titanium dioxide ($TiO_2$), hydroxyapatite (HAP) and germanium (Ge) under UV-A irradiation. At first, various type of complex catalysts were investigated to compare the enhanced photocatalytic potential. It was observed that in order to obtain the removal efficiencies were $TiO_2/HAP/Ge$ > $TiO_2/Ge$ > $TiO_2/HAP$. The composition of $TiO_2/HAP/Ge$ using a statistical approach based on mixture analysis design, one of response surface method was investigated. The independent variables of $TiO_2$ ($X_1$), HAP ($X_2$) and Ge ($X_3$) which consisted of 6 condition in each variables was set up to determine the effects on LM ($Y_1$) and TOC ($Y_2$) degradation. Regression analysis on analysis of variance (ANOVA) showed significant p-value (p < 0.05) and high coefficients for determination value ($R^2$ of $Y_1=99.28%$ and $R^2$ of $Y_2=98.91%$). Contour plot and response curve showed that the effects of $TiO_2/HAP/Ge$ composition for LM degradation under UV-A irradiation. And the estimated optimal composition for TOC removal ($Y_2$) were $X_1=0.6913$, $X_2=0.2313$ and $X_3=0.0756$ by coded value. By comparison with actual applications, the experimental results were found to be in good agreement with the model's predictions, with mean results for LM and TOC removal of 99.2% and 49.3%, respectively.

On the Characteristics of Buddhist Temples with Korean National cultural properties in Kum Kang(Kum-river) Area (금강지역의 불교건축특징)

  • Chae, Hoon Gwan;Kim, Nak Choon
    • Journal of the Korean Institute of Rural Architecture
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    • 제4권3호
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    • pp.1-11
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    • 2002
  • The aim of this research is to find-out the characteristics of Buddhist temples with relevant to Korean National cultural properties in Kum Kang(Kum-river) area. This analysis is accomplished by setting up the speciflc viewpoints where the charateristics can be perceived, and by measuring the form and angle from these points to the buddist culture ; 124 items were selected and analyzed by the comparative method. The most Important research finding is that both Traditonal Korean Temple and Kum Kang(Kum-river) Area site conceptualized and used a certain geometrical Feng-shui(geomancy) order in the disposition of mountain and river side according to the principles of human cognition. The conclusions are as follows ; Buddhist culture and the Characteristics of Buddhist temples in Kum Kang(Kum-river) Area having accumulated from the past and are the cultural complex and mixture of 7 elements. They also reflect cultural situations of each time period. The temples are a result of Korean traditional thought and spirit, as well as, regarding tradition as an important factor.

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Dissolution and Stability Enhancements of Trimethoprim by ${\beta}-Cyclodextrin$ Polymer Inclusion Complexation (트리메토프림과 ${\beta}$-시클로덱스트린 고분자 간의 포접복합체 형성에 의한 용출 및 안정성 향상)

  • Kim, Hyung-Tae;Park, Kyung-Ock;Seo, Seong-Hoon
    • Journal of Pharmaceutical Investigation
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    • 제22권2호
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    • pp.105-113
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    • 1992
  • To improve the solubility and dissolution rate of trimethoprim (TMP), which is slightly soluble drug, its inclusion complexes were prepared and studied in this experiment. Inclusion complexes of TMP with ${\beta}-cyclodextrin$ and ${\beta}-cyclodextrin$ polymer (CDPS) were prepared according to Fenyvesi method. These were compared with TMP and its physical mixture with CDPS. Water, diluted hydrochloric acid and phosphate buffer solution were used as dissolution media. And accelerated stability test was studied at $50,\;70\;and \;80^{\circ}C$. It was found that solubility and dissolution rate of inclusion complexes were increased in water. Especially, the solubility and dissolution rate of TMP was found to be markedly increased by inclusion complexation with CDPS. In stability test, ${\beta}-cyclodextrin$ inclusion complexes were more or less stable than TMP alone. This tendency was not led in CDPS. Consequently, CDPS was useful in increasing dissolution rate and stability of TMP.

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Increase of diesel car raises health risk in spite of recent development in engine technology

  • Leem, Jong Han;Jang, Young-Kee
    • Environmental Analysis Health and Toxicology
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    • 제29권
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    • pp.9.1-9.3
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    • 2014
  • Diesel exhaust particles (DEP) contain elemental carbon, organic compounds including Polyaromatic hydrocarbons (PAHs), metals, and other trace compounds. Diesel exhaust is complex mixture of thousands of chemicals. Over forty air contaminants are recognized as toxicants, such as carcinogens. Most diesel exhaust particles have aerodynamic diameters falling within a range of 0.1 to $0.25{\mu}m$. DEP was classified as a definite human carcinogen (group 1) by the International Agency for Research on Cancer at 2012 based on recently sufficient epidemiological evidence for lung cancer. Significant decreases in DEP and other diesel exhaust constituents will not be evident immediately, and outworn diesel car having longer mileage still threatens health of people in spite of recent remarkable development in diesel engine technology. Policy change in South Korea, such as introduction of diesel taxi, may raise health risk of air pollution in metropolitan area with these limitations of diesel engine. To protect people against DEP in South Korea, progressive strategies are needed, including disallowance of diesel taxi, more strict regulation of diesel engine emission, obligatory diesel particulate filter attachment in outworn diesel car, and close monitoring about health effects of DEP.

Numerical analysis on foam reaction injection molding of polyurethane, part B: Parametric study and real application

  • Han, HyukSu;Nam, Hyun Nam;Eun, Youngkee;Lee, Su Yeon;Nam, Jeongho;Ryu, Jeong Ho;Lee, Sung Yoon;Kim, Jungin
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • 제26권6호
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    • pp.258-262
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    • 2016
  • Foam reaction injection molding (FRIM) is a widely used process for manufacturing polyurethane foam with complex shapes. The modified theoretical model for polyurethane foam forming reaction during FRIM process was established in our previous work. In this study, using the modified model, parametric study for FRIM process was performed in order to optimize experimental conditions of FRIM process such as initial temperature of mold, thickness of mold, and injection amount of polymerizing mixture. In addition, we applied the modified model to real application of refrigerator cabinet to determine optimal manufacturing conditions for polyurethane FRIM process.

A Study On Heat Transfer and Flow Characteristics for Boring in Sewer by Rotating Cutter Tool (회전노즐장비 작동시 하수관내의 열전달 및 유동현상에 관한 연구)

  • Park Young-Ki;Lee Jang-Choon;Lee Dong-Joo
    • Journal of Environmental Science International
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    • 제15권1호
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    • pp.95-100
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    • 2006
  • Heat transfer and flow characteristics in a pipe in which the rotating cutting tool for boring a underground pipe without digging were considered in this study. The amount of heat generation due to the friction between the rotating cutter and pipe wall, mixing (low of air and water injected to cool down are the two important factors to design the boring machine Computational fluid dynamics analysis using the Eulerian mixture model and the standard $\kappa-\varepsilon$ turbulence model was used to analyze the complex phenomena in a pipe during the process. Results show that pipe wall temperature decreased with increasing the cooling water inlet velocity. it is also shown that pipe wail temperature was lowered when the cutter rotation speed was increased until 600 rpm. There was no further cooling effect over 600 rpm.

Investigation of Polishing Characteristics of Fused Silica Glass Using MR Fluid Jet Polishing (MR Fluid Jet Polishing 시스템에 의한 Fused Silica Glass 연마특성 고찰)

  • Lee, Jung-Won;Cho, Yong-Kyu;Cho, Myeong-Woo
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • 제21권5호
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    • pp.761-766
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    • 2012
  • Abrasive fluid jet polishing processes have been used for the polishing of optical surfaces with complex shapes. However, unstable and unpredictable polishing spots can be generated due to the fundamental property of an abrasive fluid jet that it begins to lose its coherence as the jet exits a nozzle. To solve such problems, MR fluid jet polishing has been suggested using a mixture of abrasives and MR fluid whose flow properties can be readily changed according to imposed magnetic field intensity. The MR fluid jet can be stabilized by imposed magnetic fields, thus it can remain collimated and coherent before it impinges upon the workpiece surface. In this study, MR fluid jet polishing characteristics of fused silica glass were investigated according to injection time and magnetic field intensity variations. Material removal rates and 3D profiles of the generated polishing spots were investigated. From the results, it can be confirmed that the developed MR fluid polishing system can be applied for stable and predictable precise polishing of optical parts.

Inhibitory Aromatase Effects of Flavonoids from Ginkgo Biloba Extracts on Estrogen Biosynthesis

  • Park, Yong Joo;Choo, Wun Hak;Kim, Ha Ryong;Chung, Kyu Hyuck;Oh, Seung Min
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권15호
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    • pp.6317-6325
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    • 2015
  • Ginkgo biloba extract (GBE) is a popular phytomedicine and has been used for disorders of the central nervous system, cardiovascular, renal, respiratory, and circulatory diseases. Although GBE is a complex mixture of over 300 compounds, its major components are 24% flavonoids and 6% terpene lactones. In this study, we tested the inhibitory effects of the three major flavonoids (kaempferol, quercetin, and isorhamnetin) from GBE, independently and as mixtures, on aromatase activity using JEG-3 cells (human placental cells) and recombinant proteins (human placental microsome). In both systems, kaempferol showed the strongest inhibitory effects among the three flavonoids; the flavanoid mixtures exerted increased inhibitory effects. The results of exon I.1-driven luciferase reporter gene assays supported the increased inhibitory effects of flavonoid mixtures, accompanied by suppression of estrogen biosynthesis. In the RT-PCR analysis, decreased patterns of aromatase promoter I.1 mRNA expressions were observed, which were similar to the aromatase inhibition patterns of flavonoids and their mixtures. The present study demonstrated that three flavonoids synergistically inhibit estrogen biosynthesis through aromatase inhibition, decrease CYP19 mRNA, and induce transcriptional suppression. Our results support the usefulness of flavonoids in adjuvant therapy for breast cancer by reducing estrogen levels with reduced adverse effects due to estrogen depletion.

Crowd Activity Classification Using Category Constrained Correlated Topic Model

  • Huang, Xianping;Wang, Wanliang;Shen, Guojiang;Feng, Xiaoqing;Kong, Xiangjie
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제10권11호
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    • pp.5530-5546
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    • 2016
  • Automatic analysis and understanding of human activities is a challenging task in computer vision, especially for the surveillance scenarios which typically contains crowds, complex motions and occlusions. To address these issues, a Bag-of-words representation of videos is developed by leveraging information including crowd positions, motion directions and velocities. We infer the crowd activity in a motion field using Category Constrained Correlated Topic Model (CC-CTM) with latent topics. We represent each video by a mixture of learned motion patterns, and predict the associated activity by training a SVM classifier. The experiment dataset we constructed are from Crowd_PETS09 bench dataset and UCF_Crowds dataset, including 2000 documents. Experimental results demonstrate that accuracy reaches 90%, and the proposed approach outperforms the state-of-the-arts by a large margin.

Fabrication of W-10wt.%Cu Powder for the Application of Metal Injection Molding (금속사출성형을 위한 W-10wt.%Cu 분말의 제조에 관한 연구)

  • 김순욱;손찬현;김영도;문인형
    • Journal of Powder Materials
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    • 제8권4호
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    • pp.245-252
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    • 2001
  • Recent remarkable progress in the semiconductor industry has promoted smaller size of semiconductor chips and increased amounts of heat generation. So, the demand for a substrate material to meet both the characteristics of thermal expansion coefficient and heat radiation has been on the increase. Under such conditions, tungsten(W)-copper(Cu) has been proposed as materials to meet both of the above characteristics. In the present study, the W-10wt.%Cu powders were synthesised by the mixing and hydrogen reduction of the starting mixture materials such as W-Cu, $W-CuCl_2$and $WO_3-CuCl_2$ in order to obtain the full densification. The W-10wt.%Cu produced by hydrogen reduction showed the higher interparticle friction than the simple mixed W-10wt%Cu because of the W agglomerates. In the dilatometric analysis the W-10wt.%Cu prepared from the $W-CuCl_2$was largely shrank by heating up $1400^{\circ}C$ at the constant heating rate of $5^{\circ}C$/min. The possibility of application of metal injection molding (MIM) was also investigated for mass production of the complex shaped W-Cu parts in semiconductor devices. The relationship between the temperature of molding die and the pressure of injection molding was analyzed and the heating up stage of 120-$290^{\circ}C$ in the debinding process was controlled for the most suitable MIM condition.

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