Inhibitory Aromatase Effects of Flavonoids from Ginkgo Biloba Extracts on Estrogen Biosynthesis |
Park, Yong Joo
(School of Pharmacy, Sungkyunkwan University)
Choo, Wun Hak (School of Pharmacy, Sungkyunkwan University) Kim, Ha Ryong (School of Pharmacy, Sungkyunkwan University) Chung, Kyu Hyuck (School of Pharmacy, Sungkyunkwan University) Oh, Seung Min (Department of Nanofusion Technology, Hoseo University) |
1 | Adlercreutz H (1995). Phytoestrogens: epidemiology and a possible role in cancer protection. Environ Health Perspect, 103, 103-12. DOI |
2 | Bahadoran Z, Karimi Z, Houshiar-rad A, et al (2013). Dietary phytochemical index and the risk of breast cancer: a case control study in a population of Iranian women. Asian Pac J Cancer Prev, 14, 2747-51. DOI ScienceOn |
3 | Balunas MJ, Kinghorn AD (2010). Natural compounds with aromatase inhibitory activity: an update. Planta Med, 76, 1087-93. DOI |
4 | Behan LA, Amir E, Casper RF (2015). Aromatase inhibitors for prevention of breast cancer in postmenopausal women: a narrative review. Menopause, 22, 342-50. DOI |
5 | Bernstein L, Ross RK (1993). Endogenous hormones and breast cancer risk. Epidemiol Rev, 15, 48-65. |
6 | Brueggemeier RW, Hackett JC, Diaz-Cruz ES (2005). Aromatase inhibitors in the treatment of breast cancer. Endocr Rev, 26, 331-45. DOI |
7 | Bulun SE, Sebastian S, Takayama K, et al (2003). The human CYP19 (aromatase P450) gene: update on physiologic roles and genomic organization of promoters. J Steroid Biochem Mol Biol, 86, 219-24. DOI |
8 | Cazzaniga M, Bonanni B (2012). Breast cancer chemoprevention: old and new approaches. J Biomed Biotechnol, 2012, 985620. |
9 | Chen S, Oh SR, Phung S, et al (2006). Anti-aromatase activity of phytochemicals in white button mushrooms (Agaricus bisporus). Cancer Res, 66, 12026-34. DOI ScienceOn |
10 | Chumsri S, Howes T, Bao T, et al (2011). Aromatase, aromatase inhibitors, and breast cancer. J Steroid Biochem Mol Biol, 125, 13-22. DOI |
11 | Cieza A, Maier P, Poppel E (2003). Effects of Ginkgo biloba on mental functioning in healthy volunteers. Arch of Med Res, 34, 373-81. DOI |
12 | Dubber MJ, Kanfer I (2004). High-performance liquid chromatographic determination of selected flavonols in Ginkgo biloba solid oral dosage forms. J Pharm Pharm Sci, 7, 303-9. |
13 | Eng ET, Ye J, Williams D, et al (2003). Suppression of estrogen biosynthesis by procyanidin dimers in red wine and grape seeds. Cancer Res, 63, 8516-22. |
14 | Harada N, Utsumi T, Takagi Y (1993). Tissue-specific expression of the human aromatase cytochrome P-450 gene by alternative use of multiple exons 1 and promoters, and switching of tissue-specific exons 1 in carcinogenesis. Proc Natl Acad Sci U S A, 90, 11312-6. DOI |
15 | Hong Y, Chen S (2006). Aromatase inhibitors: structural features and biochemical characterization. Ann N Y Acad Sci, 1089, 237-51. DOI |
16 | Huang SM, Temple R, Throckmorton DC, et al (2007). Drug interaction studies: study design, data analysis, and implications for dosing and labeling. Clin Pharmacol Ther, 81, 298-304. DOI |
17 | Iwase H, Yamamoto Y (2015). Clinical benefit of sequential use of endocrine therapies for metastatic breast cancer. Int J Clin Oncol, 20, 253-61. DOI |
18 | Kamat A, Alcorn JL, Kunczt C, et al (1998). Characterization of the regulatory regions of the human aromatase (P450arom) gene involved in placenta-specific expression. Mol Endocrinol, 12, 1764-77. DOI |
19 | Khan SI, Zhao J, Khan IA, et al (2011). Potential utility of natural products as regulators of breast cancer-associated aromatase promoters. Reprod Biol Endocrinol, 9, 91. DOI |
20 | Kellis JT, Jr., Vickery LE (1984). Inhibition of human estrogen synthetase (aromatase) by flavones. Science, 225, 1032-4. DOI |
21 | Kijima I, Phung S, Hur G, et al (2006). Grape seed extract is an aromatase inhibitor and a suppressor of aromatase expression. Cancer Res, 66, 5960-7. DOI |
22 | Kim MJ, Park YJ, Chung KH, et al (2013). The inhibitory effects of the standardized extracts of ginkgo biloba on aromatase activity in JEG-3 human choriocarcinoma cells. phytother res. |
23 | Kleijnen J, Knipschild P (1992). Ginkgo biloba. Lancet, 340, 1136-9. DOI |
24 | Kohler PO, Bridson WE (1971). Isolation of hormoneproducing clonal lines of human choriocarcinoma. J Clin Endocrinol Metab, 32, 683-7. DOI |
25 | Kudolo GB (2001). The effect of 3-month ingestion of Ginkgo biloba extract (EGb 761) on pancreatic beta-cell function in response to glucose loading in individuals with non-insulin-dependent diabetes mellitus. J Clin Pharmacol, 41, 600-11. DOI |
26 | Kudolo GB, Delaney DJ (2001). The effect of the ingestion of Ginkgo biloba extract on platelet lipid peroxidation. Clin Chem, 47, 51. |
27 | Lu DF, Yang LJ, Wang F, et al (2012). Inhibitory effect of luteolin on estrogen biosynthesis in human ovarian granulosa cells by suppression of aromatase (CYP19). J Agric Food Chem, 60, 8411-8. DOI |
28 | Mahmoud F, Abul H, Onadeko B, et al (2000). In vitro effects of Ginkgolide B on lymphocyte activation in atopic asthma: Comparison with cyclosporin A. Japanese J Pharmacol, 83, 241-5. DOI |
29 | Monteiro R, Azevedo I, Calhau C (2006). Modulation of aromatase activity by diet polyphenolic compounds. J Agric Food Chem, 54, 3535-40. DOI |
30 | Meiyanto E, Hermawan A, Anindyajati (2012). Natural products for cancer-targeted therapy: citrus flavonoids as potent chemopreventive agents. Asian Pac J Cancer Prev, 13, 427-36. DOI ScienceOn |
31 | Mu YM, Yanase T, Nishi Y, et al (2000). A nuclear receptor system constituted by RAR and RXR induces aromatase activity in MCF-7 human breast cancer cells. Mol Cell Endocrinol, 166, 137-45. DOI |
32 | Mukhopadhyay K, Liu Z, Bandyopadhyay A, et al (2015). Aromatase Expression Increases the Survival and Malignancy of Estrogen Receptor Positive Breast Cancer Cells. PLoS One, 10, 121136. |
33 | Oh SM, Chung KH (2004). Estrogenic activities of Ginkgo biloba extracts. Life Sci, 74, 1325-35. DOI |
34 | Oh SM, Chung KH (2006). Antiestrogenic activities of Ginkgo biloba extracts. J Steroid Biochem Mol Biol, 100, 167-76. DOI |
35 | Oh SM, Kim HR, Chung KH (2008). Effects of ginkgo biloba on in vitro osteoblast cells and ovariectomized rat osteoclast cells. Arch Pharm Res, 31, 216-24. DOI |
36 | Perez P, Pulgar R, Olea-Serrano F, et al (1998). The estrogenicity of bisphenol A-related diphenylalkanes with various substituents at the central carbon and the hydroxy groups. Environ Health Perspect, 106, 167-74. DOI |
37 | Plant N (2004). Strategies for using in vitro screens in drug metabolism. Drug Discov Today, 9, 328-36. DOI |
38 | Renoir JM, Marsaud V, Lazennec G (2012). Estrogen receptor signaling as a target for novel breast cancer therapeutics. Biochem Pharmacol. |
39 | Saarinen N, Joshi SC, Ahotupa M, et al (2001). No evidence for the in vivo activity of aromataseinhibiting flavonoids. J Steroid Biochem Mol Biol, 78, 231-9. DOI |
40 | Rigney U, Kimber S, Hindmarch I (1999). The effects of acute doses of standardized Ginkgo biloba extract on memory and psychomotor performance in volunteers. Phytother Res, 13, 408-15. DOI |
41 | Suganya J, Radha M, Naorem DL, et al (2014). In Silico docking studies of selected flavonoids--natural healing agents against breast cancer. Asian Pac J Cancer Prev, 15, 8155-9. DOI |
42 | To SQ, Knower KC, Cheung V, et al (2015). Transcriptional control of local estrogen formation by aromatase in the breast. J Steroid Biochem Mol Biol, 145, 179-86. DOI |
43 | Wang Y, Lee KW, Chan FL, et al (2006). The red wine polyphenol resveratrol displays bilevel inhibition on aromatase in breast cancer cells. Toxicol Sci, 92, 71-7. DOI |
44 | Yager JD, Davidson NE (2006). Estrogen carcinogenesis in breast cancer. N Engl J Med, 354, 270-82. DOI |
45 | Yue W, Brodie AM (1997). Mechanisms of the actions of aromatase inhibitors 4-hydroxyandrostenedione, fadrozole, and aminoglutethimide on aromatase in JEG-3 cell culture. J Steroid Biochem Mol Biol, 63, 317-28. DOI |