• 제목/요약/키워드: complex degradation

검색결과 444건 처리시간 0.025초

복합열화에 의한 형권 고정자권선의 절연신뢰성에 관한 연구 (A Study on the Insulation Reliablity of Form-Wound Stator Windings by Complex Degradation)

  • 이헌돈;김상걸;오현석;왕종배;김기준;이준웅
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 2000년도 하계학술대회 논문집
    • /
    • pp.152-155
    • /
    • 2000
  • PWM inverter-fed traction motor is able to occur problems by additive transient surge stress and harmonic loss in contrast with motor driven by 60Hz sine wave alternating source. Therefore in this paper, test method and standard of existed already were investigate, "thermal + electric" complex degradation test that considered additive degradation occurred by inverter drive carried out in order to obtain insulation reliability of traction motor driven by inverter. It seems that this test method confers large value of application at reliability estimation which the subject of complete motor not windings sample from now on.

  • PDF

CHIP promotes the degradation of mutant SOD1 by reducing its interaction with VCP and S6/S6' subunits of 26S proteasome

  • Choi, Jin-Sun;Lee, Do-Hee
    • Animal cells and systems
    • /
    • 제14권1호
    • /
    • pp.1-10
    • /
    • 2010
  • Previously we showed that CHIP, a co-chaperone of Hsp70 and E3 ubiquitin ligase, can promote the degradation of mutant SOD1 linked to familial amyotrophic lateral sclerosis (fALS) via a mechanism not involving SOD1 ubiquitylation. Here we present evidence that CHIP functions in the interaction of mutant SOD1 with 26S proteasomes. Bag-1, a coupling factor between molecular chaperones and the proteasomes, formed a complex with SOD1 in an hsp70-dependent manner but had no direct effect on the degradation of mutant SOD1. Instead, Bag-1 stimulated interaction between CHIP and the proteasome-associated protein VCP (p97), which do not associate normally. Over-expressed CHIP interfered with the association between mutant SOD1 and VCP. Conversely, the binding of CHIP to mutant SOD1 was inhibited by VCP, implying that the chaperone complex and proteolytic machinery are competing for the common substrates. Finally we observed that mutant SOD1 strongly associated with the 19S complex of proteasomes and CHIP over-expression specifically reduced the interaction between S6/S6' ATPase subunits and mutant SOD1. These results suggest that CHIP, together with ubiquitin-binding proteins such as Bag-1 and VCP, promotes the degradation of mutant SOD1 by facilitating its translocation from ATPase subunits of 19S complex to the 20S core particle.

Catechin Degradation by Several Fungal Strains Isolated from Mexican Desert

  • Aguilar Cristobal Noe;Mario Cruz;Raul Rodriguez;Gerardo Gutierrez-Sanchez;Ascencion Ramirez-Coronel;Christopher Augur
    • Journal of Microbiology and Biotechnology
    • /
    • 제14권2호
    • /
    • pp.426-429
    • /
    • 2004
  • Eleven fungal strains previously isolated from the Mexican desert were evaluated for their capacity to use catechin as carbon source in submerged cultures. At 2 g/l of catechin, all strains grew better than the control strains, Aspergillus niger Aa-20. Aspergillus niger PSH and Penicillium commune EH2 degraded 79.33% and 76.35% with degradation rates of 0.0065 and 0.0074 g/l/h, respectively, when an initial catechin concentration of 3 g/l was used. Obtained results demonstrated the potential biotechnological capacity of these fungal strains to use condensed tannins as carbon source.

Zerovalent iron-montmorillonite 복합체에 의한 chlorothalonil의 분해 (Degradation of Chlorothalonil by Zerovalent Iron-Montmorillonite Complex)

  • 최충렬;박만;이동훈;이인구;송경식;강상재;김장억
    • 한국환경농학회지
    • /
    • 제25권3호
    • /
    • pp.257-261
    • /
    • 2006
  • 본 연구에서는 유기성 화학물질로 오염된 지하수, 수질 및 토양의 효과적인 복원제로 활용되고 있는 ZVI의 반응성 및 안정성을 높이기 위하여 ZVI에 montmorillonite를 첨가하여 합성된 ZVI-Mt 복합체의 특성과 유기염소계 오염물질의 효과적인 제거제로서의 활용가능성을 조사하였다. X-선회절분석 결과 ZVI는 $44.9^{\circ}$ 부근에서 broad reflection peak를 나타내었으며, ZVI-Mt 복합체는 ZVI와 montmorillonite의 전형적인 peak가 관찰되었다. ZVI-Mt 복합체의 형태는 montmorillonite 층이 추형의 ZVI 입자를 부분적으로 둘러싸고 있었으며, ZVI가 공기 중의 산소에 의해 급격히 산화되는 것을 방지할 수 있는 구조적 형태를 나타내었다. ZVI-Mt 복합체에 의한 chlorothalonil의 분해율이 ZVI에 비해 보다 빠르고 높게 나타났으며, 반응 60분 후에는 chlorothalonil이 완전히 분해되었다. ZVI, ZVI-Mt(2:1) 및 ZVI-Mt (1:1) 모두 pH가 낮을수록 chlorothalonil의 분해가 잘 일어났으며, 모든 pH 영역에서 ZVI 보다 ZVI-Mt에 의한 chlorothalonil의 분해 효율이 높게 나타났다. 그러므로 기존의 방법에 의해 ZVI를 합성하는 것 보다는 montmorillonite를 혼합하여 복합체를 형성하는 것이 montmorillonite 층의 card section현상에 의해 ZVI의 환원력과 안정성을 증가시키는 것으로 나타났다.

Aeroengine performance degradation prediction method considering operating conditions

  • Bangcheng Zhang;Shuo Gao;Zhong Zheng;Guanyu Hu
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • 제17권9호
    • /
    • pp.2314-2333
    • /
    • 2023
  • It is significant to predict the performance degradation of complex electromechanical systems. Among the existing performance degradation prediction models, belief rule base (BRB) is a model that deal with quantitative data and qualitative information with uncertainty. However, when analyzing dynamic systems where observable indicators change frequently over time and working conditions, the traditional belief rule base (BRB) can not adapt to frequent changes in working conditions, such as the prediction of aeroengine performance degradation considering working condition. For the sake of settling this problem, this paper puts forward a new hidden belief rule base (HBRB) prediction method, in which the performance of aeroengines is regarded as hidden behavior, and operating conditions are used as observable indicators of the HBRB model to describe the hidden behavior to solve the problem of performance degradation prediction under different times and operating conditions. The performance degradation prediction case study of turbofan aeroengine simulation experiments proves the advantages of HBRB model, and the results testify the effectiveness and practicability of this method. Furthermore, it is compared with other advanced forecasting methods. The results testify this model can generate better predictions in aspects of accuracy and interpretability.

페놀수지/탄소섬유 열경화성 복합재료의 유리전이와 고온 분해과정에서 관찰되는 점탄성 특성 연구 (A Viscoelastic Study of Glass Transition and Degradation Processes of Phenolic Resin/Carbon Fiber Composites)

  • 남재도;;윤성철
    • 유변학
    • /
    • 제11권1호
    • /
    • pp.9-17
    • /
    • 1999
  • 본 연구에서는 페놀 수지/탄소섬유 복합재료가 상온에서부터 $400^{\circ}C$까지의 온도범위에서 유리 전이와 분해반응을 경험하면서 나타내는 점탄성 특징을 연구하였다. 가교 결합된 페놀메트릭스의 전형적인 유리전이에 따라 저장 탄성율(storage modulus)은 유리전이에 의하여 감소하였고 고무상태(rubbery state)에 도달함과 동시에 후경화 반응과 분해 반응 등을 포함하는 복합적인 고온반응에 의하여 증가하다가, 최대점을 보인 후 다시 감소하는 모습을 보였다. 유리전이 과정은 시간-온도 중첩원리에 따라 해석하였으나, 분해반응이 수반된 고온에서의 점탄성 특징은 저장 탄성율을 수직 및 수평 방향으로 이동시키어 마스터 커브를 완성 할 수 있었다. 이러한 실험적 결과를 토대로 아레니우스식과 Havriliak-Negami식에서 유추된 점탄성 모델을 이용하여 유리전이와 분해반응이 연속적으로 진행되는 과정을 정량적을 해석할 수 있었다. 이때의 완화시간은 유전이 과정을 통하여 감소하다가 고무상태에 이르러 최소값을 보여주고 이후로는 고온반응에 의하여 증가하는 모습을 보여주었다. 본 연구에서 제안된 점탄성 해석 방법은 반응이 수반된 열경화성 복합재료가 보여주는 점탄성 계수의 복잡한 거동을 온도와 주파수(frequency)에 따라 정확하게 묘사함으로서 이 모델링의 유용성을 증명 할 수 있었다.

  • PDF

전기철도용 견인전동기의 복합가속열화 상태진단에 관한 연구 (A Study on the Complex Accelerating Degradation and Condition Diagnosis of Traction Motor for Electric Railway)

  • 왕종배
    • 한국전기전자재료학회논문지
    • /
    • 제15권1호
    • /
    • pp.93-101
    • /
    • 2002
  • In this study, the stator form-winding sample coils based on silicone resin and polyimide were made for fault prediction and reliability estimation on the C-Class(200$\^{C}$ ) insulation system of traction motors. The complex accelerative degradation was periodically performed during 10 cycles, which was composed of thermal stress, fast rising surge voltage, vibration, water immersion and overvoltage applying. After aging of 10 cycles, the condition diagnosis test such as insulation resistance '||'&'||' polarization index, capacitance '||'&'||' dielectric loss and partial discharge properties were investigated in the temperature range of 20 ∼ 160$\^{C}$. Relationship among condition diagnosis tests was analyzed to find a dominative degradation factor and an insulation state at end-life point.

견인전동기의 복합가속열화 상태진단에 의한 고장예측 및 신뢰성 평가 (Fault Prediction & Reliability Estimation of the Traction Motor by the Complex Accelerating Degradation and Condition Diagnosis)

  • 왕종배;김명룡
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 2000년도 하계학술대회 논문집
    • /
    • pp.763-766
    • /
    • 2000
  • In this paper, stator form-winding sample coils based on silicone resin and polyimide were made for fault prediction and reliability estimation on the 200 Class insulation system of traction motors. The complex accelerative degradation was performed by periods during 10 cycles, which was composed of thermal stress, fast rising surge voltage, vibration, water immersion and overvoltage applying. After aging of 10 cycles, condition diagnosis test such as insulation resistance & polarization index, capacitance & dielectric loss and partial discharge properties were investigated in the temperature range of 20∼160$^{\circ}C$. Relationship among condition diagnosis test was analyzed to find an dominative degradation factor and an insulation state at end-life point.

  • PDF

오메프라졸과 베타-시클로덱스트린과의 포접화합물 형성에 따른 특성 (Studies on the Formation of Inclusion Complex between Omeprazole and $\beta$-cyclodextrin)

  • 소재일;이창현;이계주
    • 약학회지
    • /
    • 제35권5호
    • /
    • pp.372-378
    • /
    • 1991
  • To increase the stability and bioavailability of Omeprazole(OMP), which is used newly as a proton-pump inhibitor, inclusion complex of OMP with $\beta$-cyclodextrin($\beta$-CD) was prepared by coprecipitation method and its characteristics were ascertained by means of solubility test, DSC, IR, and the accelerated stability analysis. The type of OMP inclusion complex is classified as Bs-type on phase solubility diagram, and the stoichiometric ratio of OMP: $\beta$-CD complex is 1:2 and formation constant is 80.82/mole. The solubility of the complex could be increased remarkably by complexation compare with OMP. Degradation process of both OMP and OMP complex followed apparent first-order kinetics, of which degradation rate constants and activation energies are k$_{25}$=8.1$\times$10$^{-4}$/day, E$_{a}$=22 Kcal/mole (OMP), and k$_{25}$=4.65$\times$10$^{-6}$/day, E$_{a}$=35 Kcal/mole (complex), respectively. These results show the increase of the stability and solubility of OMP markedly, therefore it is believed that the improvement of stabilization for OMP by inclusion complexation might be practically available.

  • PDF

Interaction of pharmaceuticals with betacyclodextrin III Influence of Betacyclodextrin on Phenobarbital Hydrolysis

  • Min, Shin-Hong
    • 약학회지
    • /
    • 제16권4호
    • /
    • pp.155-161
    • /
    • 1972
  • The hydrolysis of phenobarbital is decelerated in alkaline solution by betacyclodextrin. The betacyclodextrin inhibits the degradation of phenobarbital up to 1.5 fold in the system containing 1% betacyclodextrin. The degradation mechanism in systems containing betacyclodextrin is the same that in system without complexing agent, although the rate constants are different. The pH dependence of the hydrolysis rate deceleration is compared with the ionization percent of betacyclodextrin. The results indicate that a direct relationship does not exist between the ionization of betacyclodextrin. It seems reasonable therefore that the phenobarbital undergoes a stable complex with betacyclodextrin and complex formation would provide a better shield for the phenobarbital from hydroxyl ion attack.

  • PDF