• Radiation Oncology Journal
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• v.13 no.4
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• pp.359-368
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• 1995

Purpose : This is a retrospective analysis for pattern of failure, survival rate and prognostic factors of 114 patients with histologically proven invasive cancer of the uterine cervix treated with definitive irradiation. Materials and Methods : One hundred fourteen patients with invasive carcinoma of the cervix were treated with a combination of intracavitary irradiation using Fletcher-Suit applicator and external beam irradiation by 6MV X-ray at the Ewha Womans University Hospital between March 1982 and Mar 1990. The median age was 53 years(range:30-77 years). FIGO stage distribution was 19 for IB, 23 for IIA, 42 for IIB, 12 for IIIA and 18 for IIIB. Summation dose of external beam and intracavitary irradiation to point A was 80-90 Gy(median:8580 cGy) in early stage(IB-IIA) and 85-100 Gy(median:8850 cGy) in advanced stage(IIB-IIIB). Kaplan-Meier method was used to estimate the survival rate and multivariate analysis for progrostic factors was performed using the Log likelihood for Weibull Results : The pelvic failure rates by stage were $10.5{\%}$ for IB. $8.7{\%}$ for IIA, $23.8{\%}$ for IIB, $50.0{\%}$ for IIIA and $38.9{\%}$ for IIIB. The rate of distant metastasis by stage were $0{\%}$ for IB, $8.7{\%}$ for IIA, $4.8{\%}$ for IIB. $0{\%}$ for IIIA and $11.1{\%}$ for IIIB. The time of failure was from 3 to 50 months and with median of 15 months after completion of radiation therapy. There was no significant coorelation between dose to point A($\leq$90 Gy vs >90 Gy) and pelvic tumor control(P>0.05). Incidence rates of grade 2 rectal and bladder complications were $3.5{\%}$(4/114) and $7{\%}$(8/114), respectively and 1 patient had sigmoid colon obstruction and 1 patient had severe cystitis. Overall 5-year survival rate was $70.5{\%}$ and disease-free survival rate was $53.6{\%}$. Overall 5-year survival rate by stage was $100{\%}$ for IB, $76.9{\%}$ for IIA, $77.6{\%}$ for IIB $87.5{\%}$ for IIIA and $69.1{\%}$ for IIIB. Five-rear disease-free survival rate by stage was $81.3{\%}$ for IB, $67.9{\%}$ for IIA, $46.8{\%}$ for IIB, $45.4{\%}$ for IIIA and $34.4{\%}$ for IIIB. The prognostic factors for disease-free survival rate by multivariate analysis was performance status(p= 0.0063) and response rate after completion of radiation therapy(p= 0.0026) but stage, age and radiation dose to point A were not siginificant. Conclusion : The result of radiation therapy for early stage of the uterine cervix cancer was relatively good but local control rate and survival rate in advanced stage were poor inspite of high dose irradiation to point A above 90 Gy. Prospective randomized studies are recommended to establish optimal tumor doses for various stages and volume of carcinoma of uterine cervix, And ajuvant chemotherapy or radiation-sensitizing agents must be considered to increase the pelvic control and survival rate in advanced cancer of uterine cervix.

• Journal of Digital Convergence
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• v.13 no.8
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• pp.375-385
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• 2015

This study aims to identify geographical variations and factors that affect smoking rates. The data are collected from the Community Health Survey conducted between 2009 and 2011 by Korea Centers for Disease Control and Prevention and other government organizations. Correlation and multiple regression analysis were used to examine the factors influencing smoking rates. For the purpose of investigating regional variations, we employed a decision tree model. The study has found that the significant factors associated with geographical variations in the smoking rates were the rate of hazardous drinking, the completion rate of hypertension education, the experience rate of anti-smoking campaigns, stress awareness rate, hypertension prevalence, health insurance cost, diabetes prevalence, obesity rate, and strength training rate. Convergence-based analysis on geographical variations of the smoking rates is highly important when the regionally customized healthcare programs is implemented. In the future, it is necessary to develop effective program and customized approach for the regions of high smoking rates. Our study is expected to be used as meaningful data for the design of effective health care programs and assessments to lead effective non-smoking program.

• Korean journal of applied entomology
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• v.55 no.4
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• pp.445-452
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• 2016

Exorista japonica is one of the major natural enemies of noctuid larvae, Mythimna separata and Spodoptera litura. The examined parasitoid was obtained from host species M. separata, collected at Gimje city and identified by DNA sequences (partial cytochrome oxidase I, 16S, 18S, and 28S). For purposed of this study, laboratory reared S. litura served as the host species for the development of the E. japonica. The developmental period of E. japonica immature stages were investigated at seven constant temperatures (16, 19, 22, 25, 28, 31, $34{\pm}1^{\circ}C$, RH 20~30%). Temperature-dependent developmental rates and development completion models were developed. E. japonica was successfully developed from egg to adult in $16{\sim}31^{\circ}C$ temperature regimes. Developmental duration was the shortest at $34^{\circ}C$ (8.3 days) and the longest at $16^{\circ}C$ (23.4 days) from egg to pupa development. Pupal development duration was the shortest at $28^{\circ}C$ (7.3 days). Total immature-stage development duration decreased with increasing temperature, and was the shortest at $31^{\circ}C$ (16.3 days) and the longest at $16^{\circ}C$ (45.4 days). The lower developmental threshold was $7.8^{\circ}C$ and thermal constant required to complete total immature-stage development was 370.4 degree days. Among four non-linear temperature-dependent developmental rate models, Briere 1 model had the highest adjusted R-squared (0.96). The distribution model of development completion for total immature stage development of E. japonica was well described by all model ($r^2_{adj}=0.90$) based on the standardized development duration. These results of study would be necessary not only to develop population dynamics model but also to understand fundamental biology of E. japonica.

• Archives of Pharmacal Research
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• v.10 no.1
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• pp.60-66
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• 1987

A procedure utilizing high pressure liquid chroatography coupled with UV detection is described for the determination of blood concentration of higenamine. Deproteinized serum was pretreated with$C_{18}$(Sep-pak $C_{18}$ cartridge) and the 70% EtOH eluent was applied onto a reversed-phase column ($\mu$ Bondapak $C_{18}]$) with a 15% acetonitrile in 0.05 N $NaH_2$$PO_4$-trichloroacetic acid mixed buffer (pH 2.8) as a mobile phase. With the UV detection at 232 nm, the retention times of higenamine and 1, 2, 3, 4-tetrahydropapaveroline, an internal standard, were 5.2 min and 3.9 min respectively. The blood concentration of higenamine was meausred at regular intervals after i. v. injection of higenamine to rabbit. A drastic decrease in higenamine concentration to 30% of the maximum value obtained immediately after the injection, was observed during the first 1-2 min period and thereafter the rate of decrease was slowed down. The analytical result seemed to coincide with the pharmacological effect of higenamine exerting the maximum chronotropic and hypotensive effect at the completion of the injections which were progressively recovered.

• Journal of the Ergonomics Society of Korea
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• v.30 no.2
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• pp.285-290
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• 2011

Due to the ageing-related degradation in physical and cognitive abilities, the elderly have difficulty in car driving and this is related to the high rate of car accidents among them. This study investigated the kinematic characteristics of old drivers' steering in right turning at intersections by comparing with young drivers. Thirteen old(60~70) and thirteen young(20~30) drivers who participated in the experiment turned their cars right side at intersections in a driving simulator. As results, the completion time of right turning at intersection of old drivers was larger than that of young drivers. The speeds of vehicle at the beginning and ending point of the right turning area of old drivers were smaller than those of young drivers, and also the steering angle at the ending point of the turning area of the former was smaller than that of the latter. The normalized jerk of old driver's steering was significantly larger than that of young drivers. These results indicate that old drivers modify their steering movement repeatedly and take the driving strategy of avoiding risks due to their reduced physical capabilities.

• KIEAE Journal
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• v.17 no.2
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• pp.5-12
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• 2017

Purpose: Under the purpose of presenting the adequate remodeling period for the improvement of thermal insulation performance of external walls in deteriorated buildings, the change in external wall and residential environment problem(dew condensation) due to aged deterioration after the apartments were constructed in Korea were analyzed. Method: Temperature Difference Ratio Outside(TDRo) and Heat Flow Meter(HFM) were used as measurement methods to evaluate the thermal insulation performance of deteriorated buildings. For TDR evaluation, thermo-graphic camera was used to measure and analyze the surface temperature of external wall. Also, dew condensation evaluation was analyzed using the Temperature Difference Ratio Inside(TDRi). Result: As a result of analyzing thermal performance through TDRo, the first decline point of thermal insulation performance began after 14-16 years have passed since construction was completed, and after 20 years have passed the decline point of thermal insulation performance reappeared. As a result of analyzing U-value with HFM measurement method, the decline rate of external wall's thermal insulation performance is lower than 2% in average at around 5 years after completion, and 8.7% in average at 10-15 years, and over 10.2% in average at 20 years.

• Journal of the Korea Institute of Building Construction
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• v.11 no.3
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• pp.238-246
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• 2011

Choosing the best-performance materials is a crucial task for the successful completion of a project in the construction field. In general, the process of material selection is performed through the use of information by a highly experienced expert and the purchasing agent, without the assistance of logical decision-making techniques. For this reason, the construction field has considered various artificial intelligence (AI) techniques to support decision systems as their own selection method. This study proposes the application of a systematic and efficient support vector machine (SVM) model to select optimal exterior materials. The dataset of the study is 120 completed construction projects in South Korea. A total of 8 input determinants were identified and verified from the literature review and interviews with experts. Using data classification and normalization, these 120 sets were divided into 3 groups, and then 5 binary classification models were constructed in a one-against-all (OAA) multi classification method. The SVM model, based on the kernel radical basis function, yielded a prediction accuracy rate of 87.5%. This study indicates that the SVM model appears to be feasible as a decision support system for selecting an optimal construction method.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2012.11a
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• pp.153-154
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• 2012

The accuracy of cost estimation at an early stage in school building project is one of the critical factors for successful completion. So many method and techniques have developed that can estimate construction cost using limited information available in the early stage. Among the techniques, Support Vector Machine(SVM) has received attention in various field due to its excellent capacity for self-learning and generalization performance. Therefore, the purpose of this study is to verify the applicability of cost prediction model based on SVM in school building project at the early stage. Data used in this study are 139 school building cost constructed from 2004 to 2007 in Gyeonggi-Do. And prediction error rate of 7.48% in support vector machine is obtained. So the results showed applicability of using SVM model for predicting construction cost of school building projects.

• Korean Journal of Construction Engineering and Management
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• v.4 no.4 s.16
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• pp.145-154
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• 2003

The change in environment of construction industry and the advancement of information technology require the improvement of construction project efficiency. However, construction industry still lacks performance-measuring tools that are the requirements of efficient project management system. In case of the schedule management system, schedule is usually being managed by result-oriented measurements such as completion time, spent cost, and progress rate, which are not good enough to control the overall continuity of work-flow. This research aimed to systemize the overall construction process and to develop the indicators for measuring performance of TACT activities during finishing work period that can contribute to the systemization of TACT management.

• Korean Journal of Remote Sensing
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• v.29 no.1
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• pp.115-121
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• 2013

The first geostationary satellite in Korea, COMS (Communication, Ocean, and Meteorological Satellite), has been operating properly since its successful completion of the IOT (In Orbit Test). COMS MI (Meteorological Imager) acquires Earth observation images from visible and infrared channels. This paper describes a method to compute the degradation of the COMS visible detectors and the result of the degradation during the two years of the operation. The visible channel detectors' performance was determined based on the comparison between the instrument-based measurements and ROLO model-based values. The degradation rate of the visible channel detectors of COMS MI showed a normal condition.