• Journal of Pharmacopuncture
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• v.12 no.2
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• pp.21-29
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• 2009

Objective : This study was carried to identify the anatomical component of FTMM(Foot Taeyang Meridian Muscle) in human lower limb, and further to help the accurate application to real acupuncture. Methods : FTM at the surface of the lower limb was labelled with latex. And cadaver was stripped off to demonstrate muscles, nerves and the others and to display the internal structures of FTMM, being divided into outer, middle, and inner layer. Results : FTMM in human lower limb is composed of muscles, nerves, ligaments etc. The internal composition of the FTMM in human lower limb are as follows : 1) Muscle : Gluteus maximus. biceps femoris, semitendinosus, gastrocnemius, triceps calf, fibularis brevis tendon, superior peroneal retinacula, calcaneofibular ligament, inferior extensor retinaculum, abductor digiti minimi, sheath of flexor tendon at outer layer, biceps femoris, semimembranosus, plantaris, soleus, posterior tibialis, fibularis brevis, extensor digitorum brevis, flexor digiti minimi at middle layer, and for the last time semimembranosus, adductor magnus, plantaris, popliteus, posterior tibialis, flexor hallucis longus, dorsal calcaneocuboidal ligament at inner layer. 2) Nerve : Inferior cluneal nerve, posterior femoral cutaneous n., sural cutaneous n., proper plantar branch of lateral plantar n. at outer layer, sciatic nerve, common peroneal n., medial sural cutaneous n., tibial n. at middle layer, and for the last time tibial nerve, flexor hallucis longus branch of tibial n. at inner layer. Conclusions : This study proves comparative differences from already established studies from the viewpoint of constituent elements of FTMM in the lower limb, and also in the aspect of substantial assay method. We can guess that there are conceptional differences between terms (that is, nerves which control muscles of FTMM and those which pass near by FTMM) in human anatomy.

• Herbal Formula Science
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• v.16 no.1
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• pp.131-145
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• 2008

With tablets and powder, decoction has been a widely-used method of medicine formula. However, for these formulas have unique bitter tastes and flavors of herbal component materials as it is, the compliance of herbal medicine is severly decreased especially for female and younger patients. Consequently, expected treatment effects can't be acquired completely. If loathsome tastes and flavors of decoction were effectively reduced while pharmacological activity were kept intact, the compliance could be promoted Chong-Myung-Tang has been widely prescribed for student patients with memory This study shows that Chong-Myung-Tang+chocolate have no difference from Chong-Myung-Tang in terms of pharmacological activity. Sensory difference with net chocolate was also surved. In order to observe the difference of Chong-Myung-Tang+chocolate and Chong-Myung-Tang, memory impairment was induced by intraventricular injection of $A{\beta}_{25-35}$ peptides on mice and Chong-Myung-Tang and Chong-Myung-Tang+chocolate were administered orally for 14 days. In water maze task, improvement of learning ability during acquisition period and significant increase of memory score during retention period resulted from the treatment of Chong-Myung-Tang and Chong-Myung-Tang+chocolate with respect to the $A{\beta}-injected$ control animals. Furthermore, the $A{\beta}_{25-35}$ toxicity on the hippocampus was assessed with immunohistochemistry (Bax, TUNEL), and differences in antioxidant activity was observed through TBARS and DPPH test. We employed sensory tests using chocolate flavor, herb flavor, and bitter taste & hardness as standards to show sensory differences with net chocolate. In this study, it is demonstrated that Chong-Myung-Tang+chocolate do not disturb the pharmacological activity of Chong-Myung-Tang, and have no sensory difference with net chocolate. Chong-Myung-Tang+chocolate can be used to enhance the compliance remarkably and thought of as an effective, functional formula to maximize expected treatment.

• The Journal of Korean Medicine
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• v.32 no.3
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• pp.1-9
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• 2011

Objectives: This study was carried out to observe the foot gworeum meridian muscle from a viewpoint of human anatomy on the assumption that the meridian muscle system is basically matched to the meridian vessel system as a part of the meridian system, and further to support the accurate application of acupuncture in clinical practice. Methods: Meridian points corresponding to the foot gworeum meridian muscle at the body surface were labeled with latex, being based on Korean standard acupuncture point locations. In order to expose components related to the foot gworeum meridian muscle, the cadaver was then dissected, being respectively divided into superficial, middle, and deep layers while entering more deeply. Results: Anatomical components related to the foot gworeum meridian muscle in human are composed of muscles, fascia, ligament, nerves, etc. The anatomical components of the foot gworeum meridian muscle in cadaver are as follows: 1. Muscle: Dorsal pedis fascia, crural fascia, flexor digitorum (digit.) longus muscle (m.), soleus m., sartorius m., adductor longus m., and external abdominal oblique m. aponeurosis at the superficial layer, dorsal interosseous m. tendon (tend.), extensor (ext.) hallucis brevis m. tend., ext. hallucis longus m. tend., tibialis anterior m. tend., flexor digit. longus m., and internal abdominal oblique m. at the middle layer, and finally posterior tibialis m., gracilis m. tend., semitendinosus m. tend., semimembranosus m. tend., gastrocnemius m., adductor magnus m. tend., vastus medialis m., adductor brevis m., and intercostal m. at the deep layer. 2. Nerve: Dorsal digital branch (br.) of the deep peroneal nerve (n.), dorsal br. of the proper plantar digital n., medial br. of the deep peroneal n., saphenous n., infrapatellar br. of the saphenous n., cutaneous (cut.) br. of the obturator n., femoral br. of the genitofemoral n., anterior (ant.) cut. br. of the femoral n., ant. cut. br. of the iliohypogastric n., lateral cut. br. of the intercostal n. (T11), and lateral cut. br. of the intercostal n. (T6) at the superficial layer, saphenous n., ant. division of the obturator n., post. division of the obturator n., obturator n., ant. cut. br. of the intercostal n. (T11), and ant. cut. br. of the intercostal n. (T6) at the middle layer, and finally tibialis n. and articular br. of tibial n. at the deep layer. Conclusion: The meridian muscle system seemed to be closely matched to the meridian vessel system as a part of the meridian system. This study shows comparative differences from established studies on anatomical components related to the foot gworeum meridian muscle, and also from the methodical aspect of the analytic process. In addition, the human foot gworeum meridian muscle is composed of the proper muscles, and also may include the relevant nerves, but it is as questionable as ever, and we can guess that there are somewhat conceptual differences between terms (that is, nerves which control muscles in the foot gworeum meridian muscle and those which pass nearby) in human anatomy.

• Korean Journal of Plant Taxonomy
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• v.44 no.2
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• pp.119-131
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• 2014

A comparative study of leaf anatomy in tribe Sorbarieae (Adenostoma, Chamaebatiaria, Sorbaria, Spiraeanthus) including one related genus Lyonothamnus was carried out using light microscopy. Anatomical characteristics of the leaf blade and midrib were described and taxonomically evaluated. The anatomical characters which described in this study are as follows: thickness of leaf midrib, blade in cross section, cuticle, epidermal cell, stoma, trichome, mesophyll, crystal, main vasculature type. All features were compared and the vascular patterns of midrib were distinguished two types. - Type 1: Trace tripartite (Adenostoma), Type 2: Trace continuous, subtype 2A: flat arc (Chamaebatiaria, Spiraeanthus), subtype 2B: U-shape arc (Lyonothamnus, Sorbaria). In conclusion, some of leaf anatomical characters (e.g., cuticle, epidermal cell, trichome, mesophyll, main vasculature type) can be useful for diagnostic features. Hypostomatic type, dorsiventral mesophyll, Ushape vasculature type would constitute a major characters for genus Sorbaria in Sorbarieae. The detailed anatomical description of studied taxa is provided, and its systematic importance is also briefly discussed.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.5
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• pp.416-421
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• 2015

This study was performed to comparative investigate the distribution of primary sensory and motor neurons associated with Daereung(PC7) acupoints by using neural tracing technique. A total 16 SD rats were used in the present study. After anesthesia, the rats received microinjection of 6 ㎕ of cholera toxin B subunit(CTB) into the corresponding sites of the acupoints Daereung(PC7), in the human body for observing the distribution of the related primary sensory neurons in dorsal root ganglia(DRGs) and motor neurons in the spinal cord(C3∼T4) and sympathetic ganglia. Three days after the microinjection, the rats were anesthetized and transcardially perfused saline and 4% paraformaldehyde, followed by routine section of the DRGs, sympathetic chain ganglia(SCGs) and spinal cord. Labeled neurons and nerve fibers were detected by immunohistochemical method and observed by light microscope equipped with a digital camera. The labeled neurons were recorded and counted. From this research, the distribution of primary sensory and motor neurons associated with Daereung(PC7) acupoints were concluded as follows. Muscle meridian related Daereung(PC7) controlled by spinal segments of C5∼T1, C6∼T4, respectively.

• The Korea Journal of Herbology
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• v.33 no.3
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• pp.11-18
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• 2018

Objectives : Saururus chinensis and Houttuynia cordata (Saururaceae) are perennial herbs using for medicinal purposes in Korea. The objectives of this study are to compare anatomical key characters between two medicinal plants and to provide fundamental information for the identification of two herbal medicines by using anatomical features. Methods : Cross-sections of root, rhizome, stem, petiole, and leaf for each species were observed in this study. Materials were analyzed through dehydration, paraffin embedding and micro-sectioning, and double staining with Safranin O and Fast-Green FCF. Observations of permanent preparation were conducted using light microscope. Results : S. chinensis and H. cordata were distinguished with anatomical differentiations; Idioblasts with essential oil were scattered in the parenchyma cell of cortex, pith, and phloem of S. chinensis, on the other hand, in H. cordata, idioblasts were distributed ring-shaped in the cortex of the root. S. chinensis had two cycles of vascular bundles in the stem while H. cordata had one cycle. Hypodermis layer was conspicuous in a stem of H. cordata, crystals were observed the only parenchyma in a stem of S. chinensis, and epidermal oil cells were developed in the epidermis of H. cordata. S. chinensis had air cavity at the cortex and pith of the stem. The shape of cross-section was polygonal in the stem of S. chinensis and was circular in the stem of H. cordata. Conclusions : We investigated anatomical study of Korean S. chinensis and H. cordata. To identify two herbal medicines, we considered main anatomical features and provided identification key here.

• Journal of Oriental Neuropsychiatry
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• v.24 no.1
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• pp.27-44
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• 2013

Objectives : This study was designed to investigate the effects of Gastrodia elata Blume on the improvement of memory. Methods : This study was a 12 week, double blind, comparative clinical study. There were eligible who worked with a group of healthy seniors, all 60 years of age or older. 50 subjects were randomized either to Gastrodia elata Blume in powder form and steep in hot water or placebo. We measured the faculty of memory by using K-DRS, MMSE-K, Digit Span, Letter Fluency Test, Word List Memory Test, and the Trail Making Test, and after 12 weeks we measured the faculty of memory again using the same methods. Results : Gastrodia elata Blume steeps in the hot water group significantly increased. Initiation, perseveration level, and Memory level of K-DRS and MMSE-K score. There were no considerable differences between three groups in Digit Span and Trail Making Test score. Gastrodia elata Blume group showed significant advances in Letter Fluency Test and recognition of Word List Memory Test. Conclusions : The results suggest that Gastrodia elata Blume may have positive effects on memory improvement and function of the frontal lobe activation.

• The Journal of the Korean dental association
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• v.9 no.5
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• pp.235-239
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• 1971

The effects of folic acid on the oral mucosa of albino rats were histochemically studied in the twenty four male rats, weighing abut 100gm. Seven groups of 3 each were injected with 0.2ml folic acid (folic acid 0.5mg. was dissolved in physiological saline 0.2ml) subcutaneously, during 1,2,3,5,7,10 and 14 days respectively. Oral mucosa of rats sere removed from upper molar region and fixed in 10% formalin, cold absolute alcohol, Carnoy's solution and acetone. The serial sections were histochemically stained by McManu's PAS reaction, Mowry's metachromasia, alloxan-Schiff reaction, and azo dye method for alkaline phosphatase. The comparative staining method was hematoxylin-eosin stain. The results were as follows: 1) Alkaline phosphatase reaction of stratum spinosum and stratum granulosum tended to increase after 7 and 10 days of folic acid administration. 2) PAS reactions of basement membrane and lamina propria increased after folic acid administration. 3) Metachromasia of stratum spinosum and stratum granulosum were slightly increased after 3,5 and 7days of folic acid administration and returned to the level of Control after 10 days. 4) In the oral mucosa, alloxan-Schiff reaction increased after 7 days of folic acid administration.

• Journal of Plant Biology
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• v.34 no.1
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• pp.9-18
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• 1991

This study deals with the effect of dwarf growth on xylem structure, especially on the dimension of xylem elements described for 12 species of naturally occuring dwarf trees. The length and tangential diameter of tracheary elements and fibers in dwarf trees appear to be shorter and narrower than those in normal trees. Radial width and cell number of the same annual rings are narrower and smaller in dwarf trees than those in normal trees. Height of rays in dwarf trees is lower than that in normal trees. Dwarf conifers appear to have higher ratio, of latewood to earlywood than that in normal trees. In the hardwood species studied, mesomorphy of vessel elements is lower in dwarfs than that in normal trees. It can be concluded that this dwarf growth occurs as a result of extremely slow growth by environmental stress such as water deficiency.ciency.

• Korean Journal of Veterinary Research
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• v.15 no.2
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• pp.271-277
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• 1975

한국재내산양(韓國在來山羊) 11두(頭)의 흉벽근(胸壁筋)을 절개하여 관찰하였던 바 다음과 같은 결과(結果)를 얻었다. 1. 산양(山羊)의 흉벽(胸壁)에는 횡격막을 포함하여 11개의 筋들을 확인할 수 있었다 : 전배거근(前背鋸筋) M. serratusdorsalis cranialis, 후배거근(後背鋸筋) M. serratus dorsalis caudalis, 사각근(斜角筋) M. scalenus, 늑횡근(肋橫筋) M. transversus costarum, 늑골거근(肋骨擧筋) Mm. levatores costarum, 외늑간근(外肋間筋) Mm. intercostales externi, 내늑간근(內肋間筋) Mm. intercostales interni, 늑연골간근(肋軟骨間筋) Mm. intercartilaginei, 늑골후인근(肋骨後引筋) M. retractor costae, 흉횡근(胸橫筋) M. transversus thoracis, 횡격막(橫隔膜) Diaphragma. 2. 전배거근(前背鋸筋)의 발달이 아주 미약하여 단지 1예(例)에서만 볼 수 있었다. 3. 사각근(斜角筋)은 천부(淺部)(M. scalenus supracostalis)와 심부(深部)(M. scalenus primal costae)로 구분되었으며 이들은 각각 배(背), 복(腹)으로 나누어졌고, 천부(淺部)는 제 1늑골 및 제 3~4늑골에서 기시(起始)하고 있었다. 4. 늑연골간근(肋軟骨間筋)은 제 7늑간에서는 양쪽 늑골이 서로 밀접하게 붙어있어 나타나지 않았으며, 제 1늑간 부터 제 6늑간 사이에서는 섬유방향이 거의 수평으로 향하고 있어 내늑간근(內肋間筋)의 연장으로 보이고 제 8늑간 부터 마지막 늑간사이에서는 거의 수직으로 향하고 있어 외늑간근(外肋間筋)의 연장으로 보인다.