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http://dx.doi.org/10.7231/jon.2013.24.1.027

The Verify of Memory Improvement by Gastrodia Elata Blume  

Kim, Woo-Chul (Department of Neuropsychiatry, College of Oriental Medicine, Dong-Shin University)
Jeong, Jong-Kil (Department of Herbology, College of Oriental Medicine, Dong-Shin University)
Kim, Jeong-Sang (Department of Anatomy, College of Oriental Medicine, Dong-Shin University)
Kim, Kyeong-Ok (Department of Neuropsychiatry, College of Oriental Medicine, Dong-Shin University)
Publication Information
Journal of Oriental Neuropsychiatry / v.24, no.1, 2013 , pp. 27-44 More about this Journal
Abstract
Objectives : This study was designed to investigate the effects of Gastrodia elata Blume on the improvement of memory. Methods : This study was a 12 week, double blind, comparative clinical study. There were eligible who worked with a group of healthy seniors, all 60 years of age or older. 50 subjects were randomized either to Gastrodia elata Blume in powder form and steep in hot water or placebo. We measured the faculty of memory by using K-DRS, MMSE-K, Digit Span, Letter Fluency Test, Word List Memory Test, and the Trail Making Test, and after 12 weeks we measured the faculty of memory again using the same methods. Results : Gastrodia elata Blume steeps in the hot water group significantly increased. Initiation, perseveration level, and Memory level of K-DRS and MMSE-K score. There were no considerable differences between three groups in Digit Span and Trail Making Test score. Gastrodia elata Blume group showed significant advances in Letter Fluency Test and recognition of Word List Memory Test. Conclusions : The results suggest that Gastrodia elata Blume may have positive effects on memory improvement and function of the frontal lobe activation.
Keywords
Gastrodia elata Blume; Memory; K-DRS;
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1 National Statistical Office. Estimated Future Population. 2011.
2 Cho MJ. Nationalwide Study on the Prevalence of Dementia in Korean Elders. Ministry for Health, Welfare and Family Affairs; 2008.
3 Korean Dementia Association. Dementia A Clinical Approach. Seoul: Academia; 2006;23-6, 63, 76, 391-2.
4 College of Oriental Medicine Neuropsychiatry Textbook Compilation Committee. The Oriental Neuropsychiatry. Seoul: Jipmoondang; 325-6.
5 Hwang WW, Kim JH. The Oriental Psychiatric Medicine. Seoul: Modern Medicine Publisher; 1989;605.
6 Kim CM, Shin MG, Ahn DG, et al. A Complete Translation Encyclopedia of Chinese Herbal Medicine. Seoul: Jungdam; 1999;4105-7.
7 Kim JH, Hwang HJ, Kim HY, et al. Effect of Scutellaria Baicalensis and Astrodia Elata on Learning and Memory Processes. The Journals of the Korean Oriental Medical Society. 2002;23(2):126, 134-5.
8 Choe JY. K-DRS Korean Edition Professional Outline. Seoul: Hakjisa; 1998;7-9, 12-8, 32-7.
9 Folstein MF, Folstein SE, Mchugh PR. “Minimental state”: A Practical Method for Grading the Cognitive State of Patients for Clinician. J Psychiaty Res. 1975;12:189-98.   DOI   ScienceOn
10 Kwon YC, Park JH. Standardization of Korean of the Mini-Mental State Examination (MMSE-K) for Use in the Elderly. Part II. Diagnostic Validity. Psychiatry Investigation. 1989;28(1):125-35.
11 Kim HG. Cognition Scale for Older Adults manual. Daegu: Neuropsy; 2007.
12 Spreen FO, Benton AL. Manual of Instructions for the Neurosensory Center Comprehensive Examination for Aphasia. Victoria, British Columbia, Canada: University of Victoria; 1977.
13 Kang YW, Chin JH, Duk. L. Na, et al. Brief Report: A Normative Study of the Korean Version of Controlled Oral Word Association Test (COWAT) in the Elderly. Korean Journal of Clinical Psychology. 2000;19(2):385-92.
14 Woo JI, Kim GU, Kim SY, et al. The Korean version of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD-K). Seoul: Seoul National University Publishing Department; 2003.
15 Lee KH. The Effect of Children's Field Independence - Dependence Cognitive Style and Executive Function on recall. Sungkyunkwan University master's dissertation; 2008.
16 Lee CY. The Effects of Cognitive-Behavioral Gameplay Program on the Executive Function of Young Children with Mild ADHD Symptoms. Duksung Woman's University master's dissertation; 2011.
17 Lee GG, et al. Department of Neurology, College of Medicine, Seoul National University. Neuroscience. Seoul: Beommun publisher; 2005;19-20.
18 Academy of Asian Studies. The Oriental Internal Medicine. Seoul: Yeogang Publisher; 1994;179-81.
19 Yoo HY. The Oriental Psychiatry. Seoul: Namsandang; 1988;57.
20 Heo J. Donguibogam. Seoul: The Society of Hyungsang Medicine Donguibogam publisher; 2006;2183.
21 Jung YS, Kang JH, Park SH, et al. Protective Effect of Gastrodia Elata on Neuronal Cell Damage in Alzheimer's Disease. Journal of Oriental Neuropsychiatry. 2010;21(2):136.
22 Youn YS, Lee JS. Effect of Gastrodiae Rhizoma on Apoptosis in Cerebral Infarction Induced by Middle Cerebral Artery Occlusion in Rats. Journal of Oriental Rehabilitation Medicine. 2009;19(3):1-13.
23 Lezak MD. Neuropsychological assessment. 4th ed. Oxford: Oxford University Press; 2004;371-4.
24 Moon SK, Kim YS, Park SU, et al. Effect of Gastrodia Elate BL Water Extract on Human Cerebral Blood Flow Using Transcianial Doppler. The Journals of the Korean Oriental Medical Society. 2005;26(1):115-22.