• Smart Structures and Systems
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• 제25권6호
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• pp.719-732
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• 2020

Real-time hybrid simulation (RTHS) which combines physical experiment with numerical simulation is an advanced method to investigate dynamic responses of structures subjected to earthquake excitation. The desired displacement computed from the numerical substructure is applied to the experimental substructure by a servo-hydraulic actuator in real time. However, the magnitude decay and phase delay resulted from the dynamics of the servo-hydraulic system affect the accuracy and stability of a RTHS. In this study, a robust stability analysis procedure for a general single-degree-of-freedom structure is proposed which considers the uncertainty of servo-hydraulic system dynamics. For discussion purposes, the experimental substructure is a portion of the entire structure in terms of a ratio of stiffness, mass, and damping, respectively. The dynamics of the servo-hydraulic system is represented by a multiplicative uncertainty model which is based on a nominal system and a weight function. The nominal system can be obtained by conducting system identification prior to the RTHS. A first-order weight function formulation is proposed which needs to cover the worst possible uncertainty envelope over the frequency range of interest. Then, the Nyquist plot of the perturbed system is adopted to determine the robust stability margin of the RTHS. In addition, three common delay compensation methods are applied to the RTHS loop to investigate the effect of delay compensation on the robust stability. Numerical simulation and experimental validation results indicate that the proposed procedure is able to obtain a robust stability margin in terms of mass, damping, and stiffness ratio which provides a simple and conservative approach to assess the stability of a RTHS before it is conducted.

• 한국임상약학회지
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• 제23권3호
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• pp.232-238
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• 2013

Background: Although thromboembolism is common and one of the major causes of mortality in cancer patients, maintaining therapeutic anticoagulation effect with warfarin is challenging. This study aimed to determine the prevalence and the causes of non-therapeutic INR (International Normalized Ratio) in cancer patients. Methods: Medical and pharmacy records for cancer patients managed by the pharmacist-run anticoagulation service (ACS) between May, 2010 and April, 2011 at Seoul National University Hospital were retrospectively reviewed. The causes of non-therapeutic INR were identified and compared with the results from a former study with mechanical heart valve patients. Results: A total of 335 cancer patients and 6,737 patient-visits were analyzed producing 68% (n=4,590) of non-therapeutic INR readings. Eighty-five percent of the non-therapeutic INR readings were categorized as sub-therapeutic. Frequent causes linked to non-therapeutic INR included inadequate dosage adjustment (21.8%), changes in health status (11.8%), dietary changes (8.1%), and drug interactions (4.2%). More than half of the non-therapeutic INR values had no known etiology. As causes for non-therapeutic INR, changes in health status (p<0.0001), adverse reactions (p<0.0001), and dietary changes (p=0.017) were statistically more frequent in cancer patients than in patients with mechanical heart valves. Furthermore, exposure to sub-therapeutic INR were more prevalent in cancer patients than in patients with mechanical heart valve (p<0.0001). Conclusions: This study shows that there is a tendency to keep the level of INR low and that health status change, dietary change, and drug interactions are found to be frequent causes for non-therapeutic INR in cancer patients.

• 상하수도학회지
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• 제32권6호
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• pp.507-515
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• 2018

The results of the survey on water utilization status, the wasted water factor, the awareness, and the education and promotional activities of water saving in Daejeon City are as follows: The percentage of using tap valve with a closure was 66% when showering. 74% of water was used with closing the tap valve when washing faces with no water needed, it was still considered that there existed a wasting water. The most wasting reasons of water were found to be shower, bath, and laundry in order. In the awareness of practicing tap water saving, 9.1% of respondents acted actively, 53.4% of them were trying to practice it, and more than 63% had a positive awareness. In the contents of practicing saving water, locking water when soaping while showering, non-laundry of small quantity, and using cups when brushing teeth were top priorities. About 50% of the reasons for saving water was to practice purely saving water, when saving for economic help was excluded. The level of water saving awareness was not high when considering that the ratio of usage without water saving equipment and installation, and using method was relatively high when moving in. In order to make usage of water saving equipment more common, it was deemed necessary to provide information on the purchase of water saving equipment and to promote and educate the efficiency of saving of related products. More than about 90% of the respondents responded that water saving education or promotional activities had an effect of improving water saving awareness. The most effective method of education and promotional activities was found to be 40.4% by mass media activities, and 21.7% by promotions through mobile devices.

• 영재교육연구
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• 제18권2호
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• pp.239-264
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• 2008

일반아나 학습 부진아를 대상으로 진행된 많은 선행 연구에서 출생월에 따른 학교입학연령이 아동의 학업성취에 중요한 영향을 미치는 것으로 밝혀 왔으며, 우리나라 영재아를 대상으로 진행된 본 연구에서도 이러한 양상은 그대로 적용되는 것으로 나타났다. 과학영재교육원 초 중등 영재선발 과정에 응시한, 그리고 영재로 선발된 아동의 구성원이 학교입학연령에 따라 어떠한 양상을 나타내는지 알아본 결과, 2006, 2007학년도 영재선발 응시자 및 합격자 그룹 모두 각 학년에서 나이가 가장 많은 봄 출생아의 수가 월등히 많은 것으로 나타났다. 또한 이러한 초등학교 입학연령은 초등학교뿐만 아니라 중학교 단계에까지 아동의 학업성취에 영향을 미친다는 점이 밝혀졌다. 이러한 연구 결과들을 바탕으로 학교입학연령에 따른 아동의 학업성취의 차는 이들의 성숙의 차를 의미할 수 있다는 결론을 내리게 되며 또다른 아동에 비해 일찍 학교를 입학한 상당수의 아동이 학업성취에 있어서 열세하다는 시사점도 얻게 된다. 이 외에도 이러한 요인이 일반아와 부진아뿐만 아니라 영재선발에까지도 중요한 변인으로 작용한다는 결론은 우리가 주의 깊게 고려해 보아야 할 부분일 것이다.

• 대한토목학회논문집
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• 제26권2C호
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• pp.121-131
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• 2006

국내 숏크리트 강도기준은 고강도 숏크리트의 개발과 적용이 활발한 유럽과 비교해 볼 때 상대적으로 낮게 설정되어 있어서 고강도 숏크리트의 품질을 평가하기에는 어려움이 있다. 본 연구에서는 국내 숏크리트의 강도증진과 장기 내구성을 향상시킬 수 있는 방법을 모색하기 위해 현장실험을 실시하였다. 현장실험은 고품질 혼화재와 고성능 급결제를 적용한 고강도 숏크리트를 지향하였고, 숏크리트의 강도증진에 미치는 혼화재와 급결제의 영향을 파악하고자 하였다. 그리고 유럽통합규격(EFNARC)에 의거하여 품질평가를 수행하였는데, 실험결과 알칼리프리계 급결제를 사용한 경우의 초기강도 증진율이 90~97%로 가장 높게 나타나 초기강도 증진효과에 알칼리프리계 급결제가 효과적이었다. 또한, 실리카 흄을 혼입한 숏크리트는 압축강도가 45.2~55.8MPa, 휨강도가 5.01~6.66MPa로 혼입하지 않은 경우에 비해 각각 37~79%, 17~61%의 강도증진 효과가 나타났고, 실리카 흄 치환율은 7.5~10%일 때 강도증진 효과가 가장 우수한 것으로 나타났다. 현장실험 결과 국내 숏크리트의 고강도화를 위해서는 알카리프리계 급결제와 실리카 흄과 같은 고품질 혼화재의 사용이 필요할 것으로 판단된다.

• Steel and Composite Structures
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• 제21권2호
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• pp.289-302
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• 2016

A new kind of partially precast or prefabricated castellated steel reinforced concrete beam, which is abbreviated here as CPSRC beam, was presented and introduced in this paper. This kind of CPSRC beam is composed of a precast outer-part and a cast-in-place inner-part. The precast outer-part is composed of an encased castellated steel shape, reinforcement bars and high performance concrete. The cast-in-place inner-part is made of common strength concrete, and is casted with the floor slabs simultaneously. In order to investigate the shear performance of the CPSRC beam, experiments of six CPSRC T-beam specimens, together with experiments of one cast-in-place SRC control T-beam specimen were conducted. All the specimens were subjected to sagging bending moment (or positive moment). In the tests, the influence of casting different strength of concrete in the cross section on the shear performance of the PPSRC beam was firstly emphasized, and the effect of the shear span-to-depth ratio on that were also especially taken into account too. During the tests, the shear force-deflection curves were recorded, while the strains of concrete, the steel shapes as well as the reinforcement stirrups at the shear zone of the specimens were also measured, and the crack propagation pattern together with the failure pattern was as well observed in detail. Based on the test results, the shear failure mechanism was clearly revealed, and the effect of the concrete strength and shear span-to-depth ratios were investigated. The shear capacity of such kind of CPSRC was furthermore discussed, and the influences of the holes on the steel shape on the shear performance were particularly analyzed.

• 대한기계학회논문집B
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• 제36권7호
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• pp.759-765
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• 2012

1.7L 커먼레일 직접분사 디젤 엔진을 이용하여 1500rpm 3.9bar BMEP 조건에서 세가지 연소 전략에 따른 배기가스 배출 특성 및 탄화수소 종 분석을 수행하였다. 첫째 전략은 EGR 을 사용하지 않고 연료 분할 분사를 이용하는 방법(split injection), 둘째는 적절한 EGR 적용 및 단일 연료분사 방법(single-1)이며 셋째는 다량의 EGR 및 레일 압력 증대 등을 통한 저온디젤연소(single-2)이다. 본 실험 조건으로부터 split injection 방법과 single-1 방법은 PM-NOx 상반 관계를 보였고, single-2 방법은 PM-NOx 상관관계에서 벗어나 PM 및 NOx 동시 저감이 가능하였다. 탄화수소 종 분석 결과, THC 배출 경향과 동일하게 탄소번호에 관계없이 split injection 이 가장 적은 배출을 보였고, single-1 그리고 single-2 의 순서로 많이 배출하였다. 메탄, 아세틸렌 및 CO 의 THC 에 대한 비율은 공연비가 농후해 짐에 따라서 증가하였고 이는 공연비가 농후에 따른 연소 영역에서 산소 농도 감소로 열해리가 증가하였기 때문이다.

• 한국환경과학회지
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• 제19권3호
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• pp.379-387
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• 2010

Sediments of Little Scioto (LS) River in Ohio was contaminated by poor disposal of creosote from Baker Wood Creosoting Facility. Among the primary compounds of creosote, Polycyclic Aromatic Hydrocarbons (PAHs) are the most common ingredient PAHs are known for toxic, carcinogenic and mutagenic compounds. There are many difficulties to remove the PAHs in nature environment because their characteristics are having a less water-solubility, volatile and low mobility properties as increasing the molecular weight. The generation of hydroxyl radicals (${\cdot}OH$) and hydrogen peroxide ($H_2O_2$) forms as well as high temperature (5000 K) and pressure (1000 atm) by a physico-chemical effects of ultrasound during a cavitation collapse can promote the degradation and desorption of PAHs in sediment And it can also produces shock wave and microjets which are able to change the size and surface of particle in solid-liquid system as one of physical effects. Therefore, we explored to understand the role of particle size, the effect of elimination for PAHs concentration by ultrasound and optimize the conditions for ultrasonic treatment. The condition of various size of particles (> $150{\mu}m$, < $150{\mu}m$) and solid-liquid ratio (12.5g/L, 25g/L) for the treatment was considered and ultrasonic power (430 W/L) with liquid - hexane extraction and microwave extraction method were applied after ultrasound treatment.

• Asian-Australasian Journal of Animal Sciences
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• 제20권3호
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• pp.399-404
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• 2007

To elucidate the efficacy of different levels of microbial-fermented soy proteins (FSP) on piglet performance, a total of 240 weaned piglets ($L{\times}Y{\times}D$, $22{\pm}3$ d of age, $5.16{\pm}0.07$ kg initial BW) were allotted to 4 treatment diets comprising control, FSP-3%, FSP-6% and FSP-9%. The fermented soybean product named $Pepsoygen^{(R)}$ was utilized for the study. There were 15 pigs per pen and 4 pens per treatment. The control diet contained 15% soybean meal (SBM), and SBM for the treatment diets was replaced at 3, 6 and 9% with FSP, respectively. Experimental diets were fed from 0 to 14 d (phase-I) after weaning and then a common commercial diet was fed from 15 to 35 d (phase-II). There was a linear (p<0.05) increase in ADG and ADFI at both phases of measurement. The feed to gain ratio was also improved, showing a linear (p<0.01) trend as the level of supplementation increased. Except for phosphorus, the digestibility of all other nutrients was improved linearly (p<0.05) in the FSP added diets. However, villous height and crypt depth were not affected by dietary treatments. No special effect on intestinal morphology was noticed between FSP-added and control diets. In conclusion, the growth, digestibility of nutrients and morphological changes in weaned pigs fed FSP showed improved performance at higher levels of supplementation.

• 동의생리병리학회지
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• 제16권3호
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• pp.594-601
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• 2002

The current study was carried out to evaluate neuroprotective effects of Citri Pericarpium after transient global ischemia in gerbils. Male Mongolian gerbils weighing 60-80g were anesthetized with 2% isoflurane mixed with 30% oxygen and 70 % nitrogen. Bilateral common carotid arteries were occluded for 5 minute with microaneurysm dips. On 3 or 7 days after ischemic surgery, the gerbils were sacrificed. The brain were removed, embedded in paraffin and sectioned at 8㎛-thickness. Gerbils that received ischemic insult for 5 min showed extensive neuronal damage in the hippocampal CA1 region, and the number of viable neuronal cell was 51.0±2.5/mm, 32.2% of normal group at 7 days after ischemic surgery. In animals that underwent the extract of Citri Pericarpium treatment, the number of viable neuronal cell were significantly better preserved at 110.58±3.58/mm, 72.0% of normal group than those of ischemic group (P<0.01). In the immunohistochemistry of Bax and Bcl-2, the Citri Pericarpium treated group down-regulated the expression of Bax protein at 72hr after transient global ischemia. In contrast, Bcl-2 protein level was not changed. The appearance in TUNEL assay is similar to the pattern of Bax protein. The water extract of Citri Pericarpium significantly reduced the number of TUNEL-positive CA1 pyramidal neurons at 72hr. The results suggest that Citri Pericarpium has potential neuroprotective effects in the transient global ischemia and the increase in the ratio of Bcl-2 to Bax may contribute to the anti-apoptotic effect of Citri Pericarpium.