Porcine circovirus type 2 (PCV2) is a notorious and ubiquitous virus in the swine industry. The susceptibility of the host to PCV2 infection is considered to be one factor associated with the dynamics of PCV2. The objective of this study was to verify the criteria for host susceptibility to PCV2, using blood parameters of post-weaned pigs naturally infected with the virus. The PCV2 DNA viral load, antibody titer, and leukopenia characteristics were measured in the serum extracted from the pigs at the 10th week. We classified the pigs into high (>5.0), intermediate (3.0 to 5.0), and low (<3.0) groups on the basis of the PCV2 viral load (log copies/ml), or as positive (${\leq}0.50$) and negative (>0.50) groups on the basis of antibody titer (sample-to-negative corrected ratio). Moreover, using these two categorized parameters, we suggested the criteria for classification into the susceptible and resistant groups. Statistical analyses revealed that pigs in the susceptible group had a significantly higher viral load (p<0.001) and negative antibody titer (p<0.001), as well as significantly lower leukocyte counts (p=0.018) and lower amounts of several leukocyte components (p<0.05), than pigs in the resistant group. We concluded that the susceptible group could be considered to have PCV2-induced leukopenia. Therefore, we suggest that the combined classifications of viral loads and anti-PCV2 antibodies can be used to determine PCV2-induced leukopenia in the subclinical PCV2 infection of post-weaned pig populations.
Journal of the Korea Academia-Industrial cooperation Society
/
v.17
no.8
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pp.133-139
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2016
In order to obtain a reasonable value for the thermal load to use in designs, a bridge specimen of a full-size steel box girder (bridge) was manufactured. The temperature data were measured at 21 points in the bridge specimen and 19 points in the steel box bridge. The steel box bridge specimen was installed in a similar direction to a nearby real one. The maximum effective temperatures in the bridge specimen and bridge were calculated for air temperatures in the range of $24^{\circ}C{\sim}38^{\circ}C$. The maximum effective temperature of the bridge specimen and bridge showed correlations of approximately 93.2% and 87.4%, respectively, compared with the Euro code. The maximum effective temperature calculated in this study was very close to the Euro code and the maximum temperature of the Highway Bridge Design Criteria. When the effective temperature obtained in the study is combined with the highest temperature calculated from the Contour map for each region, the design criteria for the thermal load in domestic bridge design, taking into consideration the characteristics of each region, can be established.
Recently, cabbage kimchi has occasionally been associated with the foodborne diseases of enteric viruses such as human norovirus (HuNoV). This study aimed to evaluate the correlation between microbial/physicochemical properties and persistence of HuNoV in experimentally contaminated cabbage kimchi fermented and stored at $4^{\circ}C$ or $10^{\circ}C$ for 28 days. Changes in organic acid content, lactic acid bacteria (LAB), acidity, pH, and salinity were analyzed. The recovery of structurally intact HuNoV was examined for up to 28 days post-inoculation, using a NoV GII.4 monoclonal antibody-conjugated immuno-magnetic separation method combined with quantitative real-time reverse transcription polymerase chain reaction. On day 0, LAB loads were $4.70log_{10}$ colony forming units/g and HuNoV GII.4 titers were $2.57log_{10}\;genomic\;copies/{\mu}l$, at both temperatures. After 28 days, intact HuNoV titers decreased to 1.58 ($4^{\circ}C$) and $1.04(10^{\circ}C)log_{10}\;genomic\;copies/{\mu}l$, whereas the LAB density increased. This correlated with a gradual increase in lactic acid and acetic acid at both temperatures. Our findings support a statistical correlation between changes in physicochemical properties and the recovery of structurally intact HuNoV GII.4. Moreover, we determined that the production of organic acid and low pH could affect HuNoV GII.4 titers in cabbage kimchi during fermentation. However, HuNoV GII.4 was not completely eliminated by microbial/physicochemical factors during fermentation, although HuNoV GII.4 was reduced. Based on this, we speculate that the persistence of HuNoV GII.4 may be affected by the continually changing conditions during kimchi fermentation.
This paper describes the forecast of power plant construction in a competitive korean electricity market. In Korea, KEPCO (Korea Electric Power Corporation, fully controlled by government) was responsible for from the production of the electricity to the sale of electricity to customer. However, the generation part is separated from KEPCO and six generation companies were established for whole sale competition from April 1st, 2001. The generation companies consist of five fossil power companies and one nuclear power company in Korea at present time. Fossil power companies are scheduled to be sold to private companies including foreign investors. Nuclear power company is owned and controlled by government. The competition in generation market will start from 2003. ISO (Independence System Operator will purchase the electricity from the power exchange market. The market price is determined by the SMP(System Marginal Price) which is decided by the balance between demand and supply of electricity in power exchange market. Under this uncertain circumstance, the energy policy planners such as government are interested to the construction of the power plant in the future. These interests are accelerated due to the recent shortage of electricity supply in California. In the competitive market, investors are no longer interested in the investment for the capital intensive, long lead time generating technologies such as nuclear and coal plants. Large unclear and coal plants were no longer the top choices. Instead, investors in the competitive market are interested in smaller, more efficient, cheaper, cleaner technologies such as CCGT(Combined Cycle Gas Turbine). Electricity is treated as commodity in the competitive market. The investors behavior in the commodity market shows that the new investment decision is made when the market price exceeds the sum of capital cost and variable cost of the new facility and the existing facility utilization depends on the marginal cost of the facility. This investors behavior can be applied to the new investments for the power plant. Under these postulations, there is the potential for power plant construction to appear in waves causing alternating periods of over and under supply of electricity like commodity production or real estate production. A computer model was developed to sturdy the possibility that construction will appear in waves of boom and bust in Korean electricity market. This model was constructed using System Dynamics method pioneered by Forrester(MIT, 1961) and explained in recent text by Sternman (Business Dynamics, MIT, 2000) and the recent work by Andrew Ford(Energy Policy, 1999). This model was designed based on the Energy Policy results(Ford, 1999) with parameters for loads and resources in Korea. This Korea Market Model was developed and tested in a small scale project to demonstrate the usefulness of the System Dynamics approach. Korea electricity market is isolated and not allowed to import electricity from outsides. In this model, the base load such as unclear and large coal power plant are assumed to be user specified investment and only CCGT is selected for new investment by investors in the market. This model may be used to learn if government investment in new unclear plants could compensate for the unstable actions of private developers. This model can be used to test the policy focused on the role of unclear investments over time. This model also can be used to test whether the future power plant construction can meet the government targets for the mix of generating resources and to test whether to maintain stable price in the spot market.
The dynamic behavior of dry sand under different vibration conditions is studied through laboratory experiments. Sinusoidal and random vibration experiments of sand are carried out in vertical direction under various surcharge loads. Five different sand samples are selected for the azperiment. They are composed of four different -size samples of particles and one sample which is simulated the field condition. In case of sinusoidal vibration, the change in relative density is measured with acceleration levels. To produce an acceleration, the vibration amplitude is maintained within the range of 0.4mm~0.6mm and the vibration frequency is changed within the range of 3Hz~40Hz. In case of random vibration, the combined sinusoidal acceleration is produced by a random vibration generator and the change in relative density is measured by an accelerometer. Based on the experimental results, it is found that the sandy soil is compacted to 94%~99% of relative density by vertical acceleration and the peak acceleration producing the maximum relative density is proportional to the difference between maximum and minimum void ratios. It is also found that the effect of surcharge loading : the greater the surcharge loading, the larger the change in relative density and the greater the acceleration required to change the relative density.
Ryu, Bo Rim;Kang, Ho Keun;Duong, Phan Anh;Lee, Jin Uk
Journal of Navigation and Port Research
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v.45
no.4
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pp.212-223
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2021
The objective of this study was to evaluate structural safety according to environmental conditions acting on the piping of offshore structure and the motion of the structure. As for conditions acting on the piping, the maximum and minimum temperature conditions were used to analyze the design conditions of N2 generator. The motion of the structure was calculated and applied according to the DNV(Det Norske Veritas) rule. Each condition was combined and a total of 26 load combinations were constructed according to thermal load, motion load, and presence or absence of pipe support. Analysis was performed using a commercial program MSC Patran/Nastran. Thermal analysis was performed by applying the steady-state method, Sol 153. Thermal-structural coupled analysis was performed using Sol 101, a linear-static method. As a result of the analysis, the stress tended to increase when temperature inside the pipe was lower in Set 1 and Set 2, when temperature was higher in Set 3, and when the temperature difference between the inside and outside of the pipe in Set 4 was increased. However, the sum of stresses in the condition with only temperature load and the condition with only the kinetic load did not show the same value as the stress in the composite load condition of two loads. That is, the influence of the motion load varied depending on the direction of motion, the arrangement of pipes, and the position of the support. Therefore, it is necessary to comprehensively consider the size and direction of the motion load acting on the piping, the arrangement of the piping, and the location of the pipe supports during the design of piping.
Water quality improvement processes for stagnant area consist mainly of technologies applying vegetation and artificial water circulation, and these existing technologies have some limits to handle pollution loads effectively. To improve the purification efficiency, eco-friendly technologies should be developed that can reinforce self-purification functions. In this study, a multi-functional floating island combined with physical chemical biological functions ((1) flotation and oxidization using microbubbles, (2) vegetation purification and (3) bio-filtration with improved adsorption capacity) has been developed and basic experiments were performed to determine the optimal combination conditions for each unit process. It has been shown that it is desirable to operate the microbubble unit process under conditions greater than $3.5kgf/cm^2$. In vegetation purification unit process, Yellow Iris (Iris pseudacorus) was suggested to be suitable considering water quality, landscape improvement and maintenance. When granular red-mud was applied to the bio-filtration unit process, it was found that T-P removal efficiency was good and its value was also stable for various linear velocity conditions. The appropriate thickness of filter media was suggested between 30 and 45 cm. In this study, the optimal design and operating parameters of the multi-functional floating island have been presented based on the results of the basic experiments of each unit process.
Journal of the Korea Academia-Industrial cooperation Society
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v.22
no.1
/
pp.511-519
/
2021
Slewing bearing is applied to the transmission of rotational power of the body and turret in a special vehicle for anti-aircraft weapons that overcomes the enemy flight system approaching at low altitudes with rapid response fire. When the turret load and impact load generated when shooting are combined in performing the combat mission of a special vehicle, structural stability must be secured to achieve a successful function. Among the components of the slewing bearing, the stability of the components against the complex loads acting by the turret drive and shooting was evaluated by considering the shape and material characteristics of the ring-gear, roller, and wire-race. As a research method for stability evaluation, based on engineering theory, the strength characteristics of the components were examined by numerical calculations. Finite element analysis was performed on components using the ANSYS analysis program. The results of theoretical analysis and the results of finite element analysis were very similar. A structural stability evaluation for the slewing bearing, which was performed mainly on the analysis, confirmed that the design strength of the slewing bearing determined in the preliminary design in the early stage of localization development was sufficient.
The CANDU element bowing is attributed to actions of both the thermally induced bending moments and the bending moment due to hydraulic drag and mechanical loads, where the bowing is defined as the lateral deflection of an element from the axial centerline. This paper consider only the thermally-induced bending moments which are generated both within the sheath and the fuel and sheath by an asymmetric temperature distribution with respect to the axis of an element The generalized and explicit analytical formula for the thermally-induced bending is presented in con-sideration of 1) bending of an empty tube treated by neglecting the fuel/sheath mechanical interaction and 2) fuel/sheath interaction due to the pellet and sheath temperature variations, where in each case the temperature asymmetries in sheath are modelled to be caused by the combined effects of (i) non-uniform coolant temperature due to imperfect coolant mixing, (ii) variable sheath/coolant heat transfer coefficient, (iii) asymmetric heat generation due to neutron flux gradients across an element and so as to inclusively cover the uniform temperature distributions within the fuel and sheath with respect to the axial centerline. As the results of the sensitivity calculations of the element bowing with the variations of the parameters in the formula, it is found that the element bowing is greatly affected relatively with the variations or changes of element length, sheath inside diameter, average coolant temperature and its variation factor, pellet/sheath mechanical interaction factor, neutron flux depression factor, pellet thermal expansion coefficient, pellet/sheath heat transfer coefficient in comparison with those of other parameters such as sheath thickness, film heat transfer coefficient, sheath thermal expansion coefficient and sheath and pellet thermal conductivities.
Journal of the Korean Society of Marine Environment & Safety
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v.24
no.5
/
pp.628-636
/
2018
Because large buoys are mainly made of steel, they are heavy and vulnerable to corrosion by sea water. This makes buoy installation and maintenance difficult. Moreover, vessel collision accidents with buoys and damage to vessels due to the material of buoys (e.g., steel) are reported every year. Recently, light buoys adopting eco-friendly and lightweight materials have come into the spotlight in order to solve the previously-mentioned problems. In Korea, a new lightweight buoy with a 7-Nautical Mile lantern adopting expanded polypropylene (EPP) and aluminum to create a buoyant body and tower structure, respectively, was developed in 2017. When these light buoys are operated in the ocean, the visibility and angle of light from the lantern installed on the light buoys changes, which may cause them to function improperly. Therefore, research on the performance of light buoys is needed since the weight distribution and motion characteristics of these new buoys differ from conventional models. In this study, stability estimation and motion analyses for newly-developed buoys under various environmental conditions considering a mooring line were carried out using ANSYS AQWA. Numerical simulations for the estimation of wind and current loads were performed using commercial CFD software, Siemens STAR-CCM+, to increase the accuracy of motion analysis. By comparing the estimated maximum significant motions of the light buoys, it was found that waves and currents were more influential in the motion of the buoys. And, the estimated motions of the buoys became larger as the sea state became worser, which might be the reason that the peak frequencies of the wave spectra got closer to those of the buoys.
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