• Title/Summary/Keyword: combinatorial

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Effects of annealing atmosphere on optical and electrical properties of Zn doped ITO films synthesized by combinatorial sputter system

  • Kim, In-Gi;Kim, Seong-Dae;Heo, Gi-Seok;Kim, Jin-Hyeok;Kim, Tae-Won
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2008.11a
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    • pp.153-153
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    • 2008
  • 최근 투명전극물질이 LCD, 박막태양전지, smart window, 유기발광소자 등에 폭넓게 이용됨에 따라 그 수요가 급격이 늘어나고 있다. 이러한 투명전극 물질로는 Al : ZnO, Ga : ZnO, $MgIn_2O_4$, $AgSbO_3$, $InGaZnO_4$, ITO, Zn:ITO 등이 있으며 이중 ITO 계 산화물은 우수한 전기적 특성을 바탕으로 이미 상용화 되어있는 상태이다. 그러나 ITO 계 산화물은 indium 의 희소성과 높은 가격 때문에 폭 넓은 분야의 상용화가 어려운 실정이며, 수소 플라즈마 분위기에 화학적으로 불안정한 특성은 Si 박막태양전지 응용에 큰 문제가 되고 있다. 이에 본 연구는 박막태양전지용 ITO 계 투명전극의 indium양을 줄이면서 화학적으로 안정하고, 전기적 특성이 향상된 박막을 제조하기 위해 combinatorial sputter를 이용하여 Zn의 도핑량을 연속적으로 변화시킨 ITO 박막을 제조하였다. 또한 광학적 전기적 특성의 향상을 위해 vacuum, $H_2$, $O_2$ 분위기에서 열처리 후 각 박막의 특성 변화를 관찰하였다.

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Microfluidic System Based High Throughput Drug Screening System for Curcumin/TRAIL Combinational Chemotherapy in Human Prostate Cancer PC3 Cells

  • An, Dami;Kim, Kwangmi;Kim, Jeongyun
    • Biomolecules & Therapeutics
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    • v.22 no.4
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    • pp.355-362
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    • 2014
  • We have developed a fully automated high throughput drug screening (HTDS) system based on the microfluidic cell culture array to perform combinational chemotherapy. This system has 64 individually addressable cell culture chambers where the sequential combinatorial concentrations of two different drugs can be generated by two microfluidic diffusive mixers. Each diffusive mixer has two integrated micropumps connected to the media and the drug reservoirs respectively for generating the desired combination without the need for any extra equipment to perfuse the solution such as syringe pumps. The cell array is periodically exposed to the drug combination with the programmed LabVIEW system during a couple of days without extra handling after seeding the cells into the microfluidic device and also, this device does not require the continuous generation of solutions compared to the previous systems. Therefore, the total amount of drug being consumed per experiment is less than a few hundred micro liters in each reservoir. The utility of this system is demonstrated through investigating the viability of the prostate cancer PC3 cell line with the combinational treatments of curcumin and tumor necrosis factor-alpha related apoptosis inducing ligand (TRAIL). Our results suggest that the system can be used for screening and optimizing drug combination with a small amount of reagent for combinatorial chemotherapy against cancer cells.

A Study on the AHP based Evaluation Criteria for the Combinatorial Technology of Smart Water Grid (AHP를 활용한 SWG 조합기술 평가기준에 관한 연구)

  • Kim, Yun-Jung;Kwark, Dong-Geun;Kim, Won-Tae;Kim, Jeong-Joo;Shin, Heung-Sup;Kim, Yong-Sung;Kim, Sang-Seon;Kim, Chae-Soo
    • Journal of Korean Society of Water and Wastewater
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    • v.28 no.1
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    • pp.103-110
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    • 2014
  • In this study, the evaluation criteria of performance and applicability is developed to rank the combinatorial technologies for SWG (Smart Water Grid) system using AHP (Analytic Hierarchy Process) method. Security, safety, solution, suitability and sustainability which are goals of SWG technology, are used as upper level hierarchy elements. And three detailed elements for each upper level hierarchy are adopted as the lower level hierarchy. The weighted value which represents the importance of each element, could be determined through questionnaires accomplished by groups of specialists who are engaged in relevant waster industry and research area. To assess the accuracy of the evaluation criteria developed in this study, a simulation on four decision alternatives for smart water grid was carried out as an evaluation. Consequently which showed 90 % of accuracy.

Long-term quality control of self-compacting semi-lightweight concrete using short-term compressive strength and combinatorial artificial neural networks

  • Mazloom, Moosa;Tajar, Saeed Farahani;Mahboubi, Farzan
    • Computers and Concrete
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    • v.25 no.5
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    • pp.401-409
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    • 2020
  • Artificial neural networks are used as a useful tool in distinct fields of civil engineering these days. In order to control long-term quality of Self-Compacting Semi-Lightweight Concrete (SCSLC), the 90 days compressive strength is considered as a key issue in this paper. In fact, combined artificial neural networks are used to predict the compressive strength of SCSLC at 28 and 90 days. These networks are able to re-establish non-linear and complex relationships straightforwardly. In this study, two types of neural networks, including Radial Basis and Multilayer Perceptron, were used. Four groups of concrete mix designs also were made with two water to cement ratios (W/C) of 0.35 and 0.4, as well as 10% of cement weight was replaced with silica fume in half of the mixes, and different amounts of superplasticizer were used. With the help of rheology test and compressive strength results at 7 and 14 days as inputs, the neural networks were used to estimate the 28 and 90 days compressive strengths of above-mentioned mixes. It was necessary to add the 14 days compressive strength in the input layer to gain acceptable results for 90 days compressive strength. Then proper neural networks were prepared for each mix, following which four existing networks were combined, and the combinatorial neural network model properly predicted the compressive strength of different mix designs.

Development of a Naval Vessel Compartment Arrangement Application using Differential Evolution Algorithm (Differential evolution 알고리즘을 이용한 생존성 기반의 함정 격실배치 애플리케이션 개발)

  • Kim, Youngmin;Jeong, Yong-Kuk;Ju, SuHeon;Shin, Jong-Gye;Shin, Jung-Hack
    • Korean Journal of Computational Design and Engineering
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    • v.19 no.4
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    • pp.410-422
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    • 2014
  • Unlike other weapon systems, a naval vessel has unique characteristics in that the vessel itself is a naval unit. In limited space, compartments with various objectives and characteristics need to be arranged, so that vessel performance is maximized. This paper studied a compartment arrangement algorithm that considers activity relationships among compartments and survivability of a vessel. Based on the study, a compartment arrangement application is developed that can generate various layout alternatives swiftly. The application developed in this study aims at automating a two dimensional compartment layout problem. A combinatorial optimization is performed with the differential evolution algorithm to achieve the optimized layout.

Effects of $H_2$ plasma treatments on the physical properties of Ga or Zn doped ITO films synthesized by combinatorial sputter system

  • Kim, Seong-Dae;Heo, Gi-Seok;Lee, Jong-Ho;Kim, Tae-Won
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2008.06a
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    • pp.225-225
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    • 2008
  • ITO (Indium-tin oxide) 박막은 평판디스플레이, 유기발광소자, 박막태양전지 등 다양한 광전자소자의 투명전극으로 폭 넓게 이용되고 있다. 하지만 Si 박막태양전지의 투명전극에 요구되는 특성으로는 가시광 영역에서의 고투과율 및 고전도도 외에, 수소 플라즈마 분위기에서의 화학적 고안정성이 강하게 요구된다. 왜냐하면, 최근 Si 박막태양전지의 고효율화를 위해 미결정질 Si 박막 및 나노결정 Si 박막이 이용되고 있는데, 이러한 박막은 Si 원료가스를 고농도의 수소가스로 희석한 공정조건에서 플라즈마 CVD 증착기술을 이용하여 제조되기 때문에 투명 전극재료가 화학적으로 안정하지 않으면 계면특성의 열화로 인해 태양전지 효율이 저하되는 요인으로 작용하기 때문이다. 본 연구에서는 박막태양전지용 ITO계 투명전극의 수소 플라즈마에 대한 물리적 특성 변화를 조사하기 위하여 combinatorial sputter를 이용해 Ga 및 Zn의 도핑량을 연속적으로 변화시킨 ITO 박막을 제조하였고, $H_2$ plasma 중에 일정 시간 노출 시킨 후 박막의 물리적 특성 변화를 관찰하였다.

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Combinatorial studies on the work function characteristics for Nb or Zn doped indium-tin oxide electrodes

  • Heo, Gi-Seok;Kim, Sung-Dae;Park, Jong-Woon;Lee, Jong-Ho;Kim, Tae-Won
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2008.06a
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    • pp.159-159
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    • 2008
  • Indium-tin oxides (ITO) films have been widely used as transparent electrodes for optoelectronic devices such as organic light emitting diodes (OLEDs), photovoltaics, touch screen devices, and flat-paneldisplay. In particular, to improve hole injection efficiency in OLEDs, transparent electrodes should have high work-function besides their transparency and low resistivity. Nevertheless, few studies have been made on engineering the work function of ITO for use as an efficient anode. In this study, the effects of a wide range of Nb or Zn doping rate on the changes in work functions of ITO anode were investigated. The Nb or Zn doped ITO films were fabricated on glass substrates using combinatorial sputtering system which yields a linear composition spread of Nb or Zn concentration in ITO films in a controlled manner by co-sputtering two targets of ITO and Nb2O5 or ITO and ZnO. We have also examined the resistivity, transmittance, and other structural properties of the Nb or Zn-doped ITO films. Furthermore, OLEDs employing Nb or Zn-doped ITO anodes were fabricated and the device performances were investigated concerned with the work function changes.

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ON THE SIMPLICIAL COMPLEX STEMMED FROM A DIGITAL GRAPH

  • HAN, SANG-EON
    • Honam Mathematical Journal
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    • v.27 no.1
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    • pp.115-129
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    • 2005
  • In this paper, we give a digital graph-theoretical approach of the study of digital images with relation to a simplicial complex. Thus, a digital graph $G_k$ with some k-adjacency in ${\mathbb{Z}}^n$ can be recognized by the simplicial complex spanned by $G_k$. Moreover, we demonstrate that a graphically $(k_0,\;k_1)$-continuous map $f:G_{k_0}{\subset}{\mathbb{Z}}^{n_0}{\rightarrow}G_{k_1}{\subset}{\mathbb{Z}}^{n_1}$ can be converted into the simplicial map $S(f):S(G_{k_0}){\rightarrow}S(G_{k_1})$ with relation to combinatorial topology. Finally, if $G_{k_0}$ is not $(k_0,\;3^{n_0}-1)$-homotopy equivalent to $SC^{n_0,4}_{3^{n_0}-1}$, a graphically $(k_0,\;k_1)$-continuous map (respectively a graphically $(k_0,\;k_1)$-isomorphisim) $f:G_{k_0}{\subset}{\mathbb{Z}}^{n_0}{\rightarrow}G_{k_1}{\subset}{\mathbb{Z}^{n_1}$ induces the group homomorphism (respectively the group isomorphisim) $S(f)_*:{\pi}_1(S(G_{k_0}),\;v_0){\rightarrow}{\pi}_1(S(G_{k_1}),\;f(v_0))$ in algebraic topology.

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An Efficient Vehicle Routing Heuristic for Various and Unsymmetric Forward and Backward Vehicle Moving Speed (왕복비대칭 가변이동속도에서의 효율적 배송차량경로 탐색해법 연구)

  • Moon, Geeju;Park, Sungmee
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.36 no.3
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    • pp.71-78
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    • 2013
  • An efficient vehicle routing heuristic for different vehicle moving times for forward and backward between two points is studied in this research. Symmetric distance or moving times are assumed to move back and forth between two points in general, but it is not true in reality. Also, various moving speeds along time zones are considered such as the moving time differences between rush hours or not busy daytimes. To solve this type of extremely complicated combinatorial optimization problems, delivery zones are specified and delivery orders are determined for promising results on the first stage. Then delivery orders in each zone are determined to be connected with other zones for a tentative complete delivery route. Improvement steps are followed to get an effective delivery route for unsymmetric-time-varing vehicle moving speed problems. Performance evaluations are done to show the effectiveness of the suggested heuristic using computer programs specially designed and developed using C++.

Development of New Dihydropyran Linker for Solid-Phase Reaction

  • Ryu, Joon-Hyung;Jeong, Jin-Hyun
    • Archives of Pharmacal Research
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    • v.22 no.6
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    • pp.585-591
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    • 1999
  • The linker which plays a role in connecting a polymer with a scaffold has become an important part n solid-phase reaction. To develop a new linker for alcohols and carbohydrates, dihydropyran moiety was selected in this study. New linker, 1-($4^{l},5^{l}$-dihydro-5H-pyranyl)-7-hydroxyheptan-3-one (5) was synthesized via four steps from $\delta$-valerolactone. This can be called as DDHP-linked Wang resin due to double dihy-dropyran rings. To the one pyran ring of new linker 5 was added Wang resin and other alcohols and carbohydrates as scaffolds were then added successfully to the another pyran ring. Carbohydrate and hydroxyl resins were connected via new linker in a 70% loading yield. The detachment of glucose moiety in the presence of PPTS (2 equiv.) in 1:1 n-buteanol/1,2-dichloroethane at $60^{\circ}C$ for 12 h was carried out quantitatively. When certain combinatorial chemical works are carried out using this dihydropyran linker, Wang resin itself can be recovered. Its fact is particularly very important in industry, because recovered resins can be recycled.

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