• Title/Summary/Keyword: collapsing stage

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A Case of Idiopathic Collapsing Glomerulopathy Showing Aggravation on a Chronic Progressive Course (만성신질환의 경과 중 급성 악화를 보인 허탈성 사구체병증의 진단 1예)

  • Park, Jung Min;Hwang, Mun Ju;Jeong, Yo Han;Lee, Hansol;Park, Jong Won;Kim, Yong Jin
    • Journal of Yeungnam Medical Science
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    • v.29 no.2
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    • pp.102-105
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    • 2012
  • Collapsing glomerulopathy (CG) has become an important cause of end-stage renal disease (ESRD). First delineated from other proteinuric glomerular lesions in the 1980s, CG is now recognized as a common, distinct pattern of proliferative parenchymal injury that portends a rapid loss of renal function and poor responses to empirical therapy. The first cases in the literature trace back to human-immunodeficiency-virus(HIV)-negative patients who underwent biopsy in 1979. A 45-year-old male patient complained of hematuria and proteinuria eight years ago. He showed an abrupt serum creatinine increase from 1.75 to 2.65 mg/dL in the last preceding months. Afterwards, his serum creatinine progressively increased up to 6.82 mg/dL. Moreover, his 24 h urine protein level was determined to have reached 6,171 mg/day, as opposed to 670 mg/day a year earlier. Consequently, renal biopsy was performed, and its result showed collapsing glomerulopathy, compatible with the diagnosis. He has undergone continuous ambulatory peritoneal dialysis as renal replacement therapy. Thus, it is reported herein that a patient clinically diagnosed with chronic kidney disease eight years ago showed a sudden renal-function decrease and was clinicopathologically diagnosed with collapsing glomerulopathy based on the results of his renal biopsy.

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Altered Peripheral Nerve Excitability Properties in Acute and Subacute Supratentorial Ischemic Stroke (급성 및 아급성 천막상 허혈성 뇌졸중에서 발생하는 말초신경 흥분성 변화)

  • Seo, Jung Hwa;Ji, Ki Whan;Chung, Eun Joo;Kim, Sang Gin;Kim, Oeung Kyu;Paeing, Sung Hwa;Bae, Jong Seok
    • Annals of Clinical Neurophysiology
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    • v.14 no.2
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    • pp.64-71
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    • 2012
  • Background: It is generally accepted that upper motor neuron (UMN) lesion can alter lower motor neuron (LMN) function by the plasticity of neural circuit. However there have been only few researches regarding the axonal excitability of LMN after UMN injury especially during the acute stage. The aim of this study was to investigate the nerve excitability properties of the LMNs following an acute to subacute supratentorial corticospinal tract lesion. Methods: An automated nerve excitability test (NET) using the threshold tracking technique was utilized to measure multiple excitability indices in median motor axons of 15 stroke patients and 20 controls. Testing of both paretic and non-paretic side was repeated twice, during the acute stage and subacute stage. The protocols calculated the strength-duration time constant from the duration-charge curve, parameters of threshold electrotonus (TE), the current-threshold relationship from sequential sub-threshold current, and the recovery cycle from sequential supra-threshold stimulation. Results: On the paretic side, compared with the control group, significant decline of superexcitablity and increase in the relative refractory period were observed during the subacute stage of stroke. Additionally, despite the absence of statistical significance, a mildly collapsing in ('fanning in') of the TE was found. Conclusions: Our results suggest that supratentorial brain lesions can affect peripheral axonal excitability even during the early stage. The NET pattern probably suggests background membrane depolarization of LMNs. These features could be associated with trans-synaptic regulation of UMNs to LMNs as one of the "neural plasticity" mechanisms in acute brain injury.

Development of Falling-sensing Terminals and a System with Relay Function (중계 기능을 갖는 낙상 감지 단말기 및 시스템의 개발)

  • Jang, Duk-Sung
    • IEMEK Journal of Embedded Systems and Applications
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    • v.11 no.3
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    • pp.173-181
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    • 2016
  • Several falling-sensing terminals have been developed which are able to detect the fall/upset accident of the elderly and transmit the collapsing signals to the administrative server via RF communication using 400MHz bandwidth. Supposing there might be no communication problem within a sanatorium, just single terminal without relay function had been made as a prototype in the first stage of development. However some communication problems have discovered at the coner of the floor apart from the other floor diagonally in the same building. Same kind of problems have been happened in the area behind a steel fence or a car. To solve these kinds of communication problems, we have developed several terminals and added up relay function to them. In this paper we represented that the success ratio of the communication has been improved by using relay function among several terminals.

Electron-Microscopic Studies on the Spermiogenesis and Spermatozoa of the Allied Rock Wallaby(Petrogale assimilus) (캥거루우(Allied Rock Wallaby, Petrogale assimilus)의 정자완성(精子完成)과 정자(精子)에 관한 전자현미경적(電子顯微鏡的) 연구(硏究))

  • Kim, J.W.;Harding, H.R.;Shorey, C.D.
    • Applied Microscopy
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    • v.17 no.1
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    • pp.1-15
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    • 1987
  • Testes from the allied rock wallaby(Petrogale assimilus) have been examined by the electron microscopy in thin sections in order to examine spermiogenesis and structure of spermatozoa. The spermiogenesis can be divided into nine stages: early Golgi, late Golgi, collapsing, nuclear protrusion, condensation and flattening, nuclear shaping, rotation, nuclear ring contraction, and maturation. The acrosome has been abruptly formed following the collapse of expanded acrosomal vesicle without the cap stage described in the eutheria. The flatly condensed nucleus rotates obliquely to the axis of the axial filament complex and the folded acrosome covers the anterior third of the dorsal nuclear surface forming a wide subacrosormal space as the nuclear ring has contracted. The Sertoli cell reaction and spur are prominent during the nuclear protrusion and rotation stages. A mature spermatozoon has S-shape head which has an extended part reaching to the vicinity of the middle piece.

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Phenomenological Study on the Essential Meaning of Gentile New Yorkers -Focusing on Fashion Designers and Advertising Designers- (이방인 뉴요커의 본질적 의미에 대한 현상학적 연구 -패션디자이너와 광고디자이너를 중심으로-)

  • Oh, Hyun Jeong
    • Journal of the Korean Society of Clothing and Textiles
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    • v.39 no.6
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    • pp.910-923
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    • 2015
  • This phenomenological study is to understand the meaning and essence of experience from the perspective of a New Yorker. Participants were 11 Korean single women around 30 years old who work as fashion designers or advertising designers living and working in New York. Data were collected from November, 2013 to February, 2014, and one-to-one in-depth interviews were performed for data collection. Data analysis used the descriptive phenomenological method proposed by Giorgi. Phenomenological research is useful to understand the meaning of the experience for select cases and is used as an epoch and free variation method. The study results were identified from 70 common meanings to 14 exposed themes and 4 essentially themes from a gentile New Yorker's experience. The 4 essential themes were as follows. 1) Self-realization at the highest stage, 2) Indulge in the advanced culture of affluence and freedom, 3) Collapsing every day in depressed foreign workers, and 4) Becoming a rootless gentile New Yorker.

A Study on Product Planning of Knitwear Commodity (니트웨어 상품 기획의 실제적 연구)

  • Lee, In-Suk;Cho, Kyu-Hwa
    • Journal of Fashion Business
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    • v.12 no.1
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    • pp.1-15
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    • 2008
  • This study aims to consolidate the qualitative growth of knit design thru the creation of high value-added brand and design, in the state of active trend for competitive promotion of professional knit brand, by collapsing the border line between the knitwear market and the woven one. In accordance with the market situation of increasing a demand of knitwear products, I wish to awaken the importance of knit design thru this study, to survey domestic knit brand products and their planning directions and to plan for the high value-added knitwear products, thru presenting the problems of knit industry and developing knitwear design. This study is focused on showing process of planning and items developed personally by me in charge of developing products practically at the job site of knit industry. From the stage of planning for goods, I suggested the 2007 s/s goods of M company as a strategy of distinctiveness caused by the problems with rival companies, and also proposed a method conducted by the actual business. Setting up M company's s/s concept of the year 2007, I suggested a plan of quantity, time of forwarding, color, fabrics, etc. as well as the process and schedule thru order, and based on the above result, I made a planning for 2007 s/s knitwear for middle-aged women.

Development of Schizogenous and Lysigenous Aerenchyma in Rice Root

  • Kang, Si-Yong;Wada, Tomikichi;Choi, Kwan-Sam
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.43 no.2
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    • pp.77-82
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    • 1998
  • Aerenchyma development in rice (Oryza sativa L.) roots is quite important for adaptation to waterlogged or reduced soil conditions. Anatomical observations were carried out to clarify the development of schizogenous and lysigenous aerenchyma in elongating crown roots of rice. The crown roots of 3rd and 4th phytomer were taken from rice plants of the 8th leaf stage grown by hydroponic culture. The schizogenous intercellular spaces in the cortex of crown root tip were observed using a light microscope with semi ultra-thin sections and the lysigenous aerenchyma in mature tissue of crown root were observed using a cryo scanning electron microscope (cryo-SEM) with freezing fracture method. The schizogenous intercellular spaces in the root tip exist obviously in the middle portion of cortical cell layers close to the root-root cap junction, but not in root cap, stele and outer cell layers of cortex. The air spaces were formed at the junction of four neighbouring cells of inner cortex in the transverse sections, and between longitudinal cell layer connected along the root axis. Although many of those spaces were filled with liquid, some spaces seem to exist as air spaces. The lysigenous aerenchyma in the cortex, which hardly filled with liquid, emerged at 3-4 cm segment from the root tip and increased toward the basal region of root axis. The developing process of lysigenous aerenchyma was primarily separation of a radial row of cells caused by the shrinking and collapsing of cortical cells and then formation of septa along the radial cell rows by the fusion of cell wall with each other. These results suggest that the schizogenous and lysigenous aerenchyma playa role as a passage for the movement of oxygen into the root tip region where oxygen is required for respiration.

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DEUTERATED METHANOL (CH3OD) IN THE HOT CORE OF THE MASSIVE STAR-FORMING REGION DR21 (OH) (무거운 별 탄생 지역인 DR21(OH) 천체에 대한 중수소화된 메탄올(CH3OD) 관측연구)

  • Minh, Young Chol
    • Publications of The Korean Astronomical Society
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    • v.29 no.2
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    • pp.29-34
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    • 2014
  • We have observed the deuterated methanol, $CH_3OD$, toward the hot core MM1 in the massive star-forming region DR21 (OH) using the Submillimeter Array with a high angular resolution of about 1 arcsecond. The position of the hot core associated with the sub-core MM1a was confirmed to coincide with the continuum peak where an embedded young stellar object is located. The column density of $CH_3OD$ was found to be about $(2{\pm}1){\times}10^{16}cm^{-2}$ toward the MM1a center. The abundance ratio $CH_3OD/CH_3OH$ was measured to be ~ 0.45, which is about the median value for low mass star-forming cores but much larger than those of the massive star-forming cores. The ratio is believed to change depending on, for example, the chemical condition, the temperature and the density of the source. This ratio may further depend on the evolutionary phase especially in the massive-star-forming cores. The sub-core MM1a is thought to be in the very early phase of star formation. This large abundance ratio found in this source indicates that even the massive star-forming cores, during a relatively short period in the very early stage of star formation, may also show a chemical state resulted from the cold and dense pre-collapsing phase, the enhanced deuteration as found in low mass star-forming cores.

Improvement of Fire Detection in Rack-type Warehouses using FDS (FDS를 이용한 랙크식 창고의 화재감지 개선에 관한 연구)

  • Choi, Ki-Ok;Park, Moon-Woo;Choi, Don-Mook
    • Fire Science and Engineering
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    • v.33 no.5
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    • pp.55-60
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    • 2019
  • The occurrence of fire in rack-type warehouses may either lead to the warehouses getting entirely burned up or collapsing. This can be attrubuted to the high height of rack-type warehouses, in which combustibles are generally vertically stacked. These characteristics make it difficult to detect a fire early; because detectors are installed on the ceiling, these fires cannot be extinguished at an early stage. In this study, the flow of heat and smoke generated by a fire in a rack-type warehouse was analyzed using a fire dynamic simulator. Through this analysis, the optimal installation conditions of fire detectors for the early detection of fire in rack-type warehouses were confirmed. The analysis results confirmed that complex detection of heat and smoke is required for the early detection of fire in rack type warehouses. Furthermore, it was found that fixed temperature detectors are not suitable for these warehouses, resulting in the need to install heat-smoke hybrid detectors at every three rack levels.

Structural Geometry, Kinematics and Microstructures of the Imjingang Belt in the Munsan Area, Korea (임진강대 문산지역의 구조기하, 키네마틱스 및 미세구조 연구)

  • Lee, Hyunseo;Jang, Yirang;Kwon, Sanghoon
    • Economic and Environmental Geology
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    • v.54 no.2
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    • pp.271-283
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    • 2021
  • The Imjingang Belt in the middle-western Korean Peninsula has tectonically been correlated with the Permo-Triassic Qinling-Dabie-Sulu collisional belt between the North and South China cratons in terms of collisional tectonics. Within the belt, crustal-scale extensional ductile shear zones that were interpreted to be formed during collapsing stage with thrusts and folds were reported as evidence of collisional events by previous studies. In this study, we tried to understand the nature of deformation along the southern boundary of the belt in the Munsan area based on the interpretations of recently conducted structural analyses. To figure out the realistic geometry of the study area, the down-plunge projection was carried out based on the geometric relationships between structural elements from the detailed field investigation. We also conducted kinematic interpretations based on the observed shear sense indicators from the outcrops and the oriented thin-sections made from the mylonite samples. The prominent structures of the Munsan area are the regional-scale ENE-WSW striking thrust and the N-S trending map-scale folds, both in its hanging wall and footwall areas. Shear sense indicators suggest both eastward and westward vergence, showing opposite directions on each limb of the map-scale folds in the Munsan area. In addition, observed deformed microstructures from the biotite gneiss and the metasyenite of the Munsan area suggest that their deformation conditions are corresponding to the typical mid-crustal plastic deformation of the quartzofeldspathic metamorphic rocks. These microstructural results combined with the macro-scale structural interpretations suggest that the shear zones preserved in the Munsan area is mostly related to the development of the N-S trending map-scale folds that might be formed by flexural folding rather than the previously reported E-W trending crustal-scale extensional ductile shear zone by Permo-Triassic collision. These detailed examinations of the structures preserved in the Imjingang Belt can further contribute to solving the tectonic enigma of the Korean collisional orogen.