• Title/Summary/Keyword: cold sensitivity

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Study of the Relationship between the Pain and the Weather (통증과 날씨와의 관련성 연구)

  • Lee, Chong-Woo;Kwon, Young-Dal
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.21 no.2
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    • pp.571-577
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    • 2007
  • The purpose of this study was to investigate the relationship between the pain and the weather. One hundred ninety three patients treated for pain were recruited for this study. All subjects completed a 8-item weather and pain questionnaire to find out whether the pain are related to change in the weather, Of all subjects, 126 patients(65.3%) believed that change in the weather affected their pain. Of theses 126 patients, 85 patients(67.5%) reported that their pain was affected before weather changes, 44 patients(34.9%) stated that their pain was affected during weather changes. Damp/Rainy(n=91, 72.2%) and cold(n=60, 47.6%) conditions were mostly considered to have influence on pain. Of all subjects, 125 patients(64.8%) believed that change in the weather affected their mood. In the female group, a tendency to have pain or mood sensitivity to change in the weather was significantly higher than the male group(p=0.006, p=0.003) In the non-religious group, a tendency to have pain or mood sensitivity to change in the weather was significantly higher than the religious group(p=0.006, p=0.004). Of the pain sensitive group to change in the weather, 97 patients(77.0%) reported that they also have mood sensitivity to change in the weather(p=0.000). In the pain or mood sensitive group to change in the weather, their pain intensity(VAS) was significantly higher than the other group(p=0.000, p=0.021). The results of this survey give support to the idea that most patients with pain believe that weather has an important impact on their pain. Further investigations are needed to identify the mechanisms involved in the effects of weather changes on pain.

The Evaluation of Usefulness of Pixelated Breast-Specific Gamma Imaging in Thyroid scan (Pixelated Breast-Specific Gamma Imaging(BSGI) 감마 카메라를 이용한 갑상선 검사의 유용성 평가)

  • Jung, Eun-Mi;Seong, Ji-Hye;Yoo, Hee-Jae
    • The Korean Journal of Nuclear Medicine Technology
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    • v.15 no.1
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    • pp.90-93
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    • 2011
  • Purpose: A Pixelated BSGI gamma camera has features to enhance resolution and sensitivity and minimize the distance between detector and organs by narrow FOV. Therefore, it is known as useful device to examine small organs such as thyroid, parathyroid and gall bladder. In general, when we would like to enlarge the size of images and obtain high resolution images by gamma camera in nuclear medicine study, we use pinhole collimator. The purpose of this study is to evaluate the usefulness of Pixelated BSGI gamma camera and to compare to it using pinhole collimator in thyroid scan which is a study of typical small organs. Materials and methods: (1) The evaluation of sensitivity and spatial resolution: We measured sensitivity and spatial resolution of Pixelated BSGI with LEHR collimator and Infinia gamma camera with pinhole collimator. The sensitivity was measured by point source sensitivity test recommended by IAEA. We acquired images considering dead time in BSGI gamma camera for 100 seconds and used $^{99m}TcO4-\;400{\mu}Ci$ line source. (2) The evaluation of thyroid phantom: The thyroid phantom was filled with $^{99m}TcO4-$. After set 300 sec or 100 kcts stop conditions, we acquired images from both pixelated BSGI gamma camera and Infinia gamma camera with LEHR collimator. And we performed all thyroid studies in the same way as current AMC's procedure. Results: (1) the result of sensitivity: As a result, the sensitivity and spatial resolution of pixelated BSGI gamma camera were better than Infinia's. The sensitivities of pixelated BSGI and Infinia gamma camera were $290cps/{\mu}Ci$ and $350cps/{\mu}Ci$ respectively. So, the sensitivity of pixelated BSGI was 1.2 times higher than Infinia's (2) the result of thyroid phantom: Consequently, we confirmed that images of Pixelated BSGI gamma camera were more distinguishable between hot and cold spot compared with Infinia gamma camera. Conclusion: A pixelated BSGI gamma camera is able to shorten the acquisition time. Furthermore, the patients are exposed to radiation less than before by reducing amount of radiopharmaceutical doses. Shortening scan time makes images better by minimizing patient's breath and motion. And also, the distance between organ and detector is minimized because detector of pixelated BSGI gamma camera is small and possible to rotate. When patient cannot move at all, it is useful since device is feasible to move itself. However, although a pixelated BSGI gamma camera has these advantages, the effect of dead time occurs over 2000 cts/s since it was produced only for breast scan. So, there were low concentrations in organ. Therefore, we should consider that it needs to take tests to adjust acquisition time and amount of radiopharmaceutical doses in thyroid scan case with a pixelated BSGI gamma camera.

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Effects of GaAs (904 nm) Low Level Laser Therapy on Dentin Hypersensitivity (과민치아에 대한 904nm GaAs 반도체레이저의 효과)

  • Won, Tae-Hee;Kim, Ki-Suk
    • Journal of Oral Medicine and Pain
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    • v.36 no.4
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    • pp.215-224
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    • 2011
  • The aim of the study was to investigate the effects of 904 nm GaAs laser irradiation for patients with hypersensitive teeth and to find the possibility of clinical use of this Low Level Laser Therapy (LLLT) for the control of hypersensitive teeth. Eleven patients visited Dept. of Oral Medicine, Dankook University participated in this study. Each patient contributed at least two or more contralateral pairs of hypersensitive teeth with exposed dentine at cervical surfaces. Total number of teeth used from subjects participated in this study was 50: 25 experimental and control teeth respectively. All participants were treated with 904 nm GaAs diode laser every week during 4 weeks. Tactile and cold (ice stick) tests were carried out before LLLT every week during 4 weeks and 1 week later after the last LLLT by measuring visual analogue scale (VAS) of patients and by measuring a score of electrical pulp tester (EPT) simultaneously. The VAS score in tactile test decreased significantly with time, but there was not statistically difference between those of groups. The score of EPT in the experimental group was significantly higher than that of control group, although there was no change with time. In cold test, there was significant difference between two groups and cold sensitivity of the experimental group significantly decreased with time after every LLL irradiation, compared with that of control group. Based on the results, it is suggested that the 904 nm GaAs laser irradiation could be positively used as an effective, reversible method in treating cervical dentine hypersensitivity.

The effects of rolling process on microstructures and high temperature tensile properties of Al-Mg alloy (Al-Mg합금의 압연변수에 다른 미세구조의 변화와 고온인장특성)

  • Kim, Tae-Kue;Jeon, C.H.;Kwun, S.I.;Park, Jong-Woo
    • Journal of the Korean Society for Heat Treatment
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    • v.10 no.2
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    • pp.81-92
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    • 1997
  • The effect of alloying elements, precipitate size, its distribution, and dislocation substructure resulted from warm rolling or cold rolling in the superplastic Al-Mg alloy system was investigated. One of the major requirements for fine structure superplasticity is that the grain size should be very small. Fine grain structure is controlled by the dislocation substructure and the dynamic recrystallization during hot or warm working. The recovery of Al-Mg base alloys was constrained resulting in relatively high dislocation density when the alloys were warm rolled. In particular, Al-Mg-Zr alloy exhibited the smallest sub-grain size among Al-Mg alloys containing Mn, Cu, Zr as a third element. The Al-Mg-Mn alloy cold rolled 80% after hot rolling showed the maximun strain rate sensitivity exponent, m, of 0.75 under strain rate of $7.1{\times}10^{-4}/s$ at $500^{\circ}C$. The elongation of the alloys was limited in spite of high m values due to large dispersoids containing appreciable amount of Fe impurities.

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Pile bearing capacity prediction in cold regions using a combination of ANN with metaheuristic algorithms

  • Zhou Jingting;Hossein Moayedi;Marieh Fatahizadeh;Narges Varamini
    • Steel and Composite Structures
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    • v.51 no.4
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    • pp.417-440
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    • 2024
  • Artificial neural networks (ANN) have been the focus of several studies when it comes to evaluating the pile's bearing capacity. Nonetheless, the principal drawbacks of employing this method are the sluggish rate of convergence and the constraints of ANN in locating global minima. The current work aimed to build four ANN-based prediction models enhanced with methods from the black hole algorithm (BHA), league championship algorithm (LCA), shuffled complex evolution (SCE), and symbiotic organisms search (SOS) to estimate the carrying capacity of piles in cold climates. To provide the crucial dataset required to build the model, fifty-eight concrete pile experiments were conducted. The pile geometrical properties, internal friction angle 𝛗 shaft, internal friction angle 𝛗 tip, pile length, pile area, and vertical effective stress were established as the network inputs, and the BHA, LCA, SCE, and SOS-based ANN models were set up to provide the pile bearing capacity as the output. Following a sensitivity analysis to determine the optimal BHA, LCA, SCE, and SOS parameters and a train and test procedure to determine the optimal network architecture or the number of hidden nodes, the best prediction approach was selected. The outcomes show a good agreement between the measured bearing capabilities and the pile bearing capacities forecasted by SCE-MLP. The testing dataset's respective mean square error and coefficient of determination, which are 0.91846 and 391.1539, indicate that using the SCE-MLP approach as a practical, efficient, and highly reliable technique to forecast the pile's bearing capacity is advantageous.

Cold Shock Response and Low Temperature Stable Transcript of DEAD-box RNA Helicase in Bacillus subtilis (DEAD-box RNA Helicase 유전자가 결핍된 Bacillus subtilis의 저온 충격 반응성과 저온 안정성 전사물)

  • Oh, Eun-Ha;Lee, Sang-Soo
    • Korean Journal of Microbiology
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    • v.47 no.4
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    • pp.289-294
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    • 2011
  • We investigated the cold shock sensitivity of DEAD-box RNA helicase gene deleted strains of in Bacillus subtilis CU1065. To understand cold shock effects, cells were cultivated at $37^{\circ}C$ to log phase ($O.D_{600}$=0.5-0.6) and then temperature was shifted to $15^{\circ}C$. Cold shock slow down the growth rate of wild type and deleted strains of DEAD-box RNA helicase gene (ydbR, yfmL, yqfR, deaD). The growth rate of ydbR deleted strain is 5 times severely reduced compared to that of wild type strain (CU1065). But the growth rate of other three (yfmL, yqfR, deaD) deleted strains is nearly equal to the growth rate of wild type. Compared to $37^{\circ}C$, the amount of ydbR and yqfR mRNA transcripts are increased at the growth temperature of $15^{\circ}C$. On the other hands the mRNA transcripts of yfmL and deaD are not changed at both conditions of $37^{\circ}C$ and $15^{\circ}C$. Upon cold shock treatment ydbR mRNA transcript is clearly increased. After treatment of rifampicin (bacteria transcription inhibitor) the amount of ydbR mRNA was measured. Temperature shift from $37^{\circ}C$ to $15^{\circ}C$ and rifampicin treatment showed slowly decay of ydbR mRNA. But at $37^{\circ}C$ and rifampicin treatment ydbR mRNA is rapidly reduced. These results showed that cold shock induction of ydbR mRNA resulted from the stability of ydbR mRNA and not from the transcription induction of ydbR. In relation to these results, we found the cold box element of csp (cold shock protein gene) in 5' untranslated region of ydbR gene. Cold shock induction of ydbR is caused by the stability of ydbR mRNA like the stability of csp mRNA.

Synthesis and Characterization of Comb-Type Grafted Polymer Hydrogels with Low Temperature Sensitivity (저온 감열 특성을 가지는 Comb-Type Grafted Polymer Hydrogels의 합성 및 특성평가)

  • Taek Kyu Jung;Sung Soo Kim;Byung Cheol Shin
    • Journal of the Korean Chemical Society
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    • v.47 no.1
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    • pp.59-66
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    • 2003
  • The comb-type grafted polymer hydrogels, which composed of N-isopropylacrylamide monomer and oligo(N-isopropylacrylamide-co-tert-butylacrylamide) [oligo(NIPAAm-co-t-BAM)], were synthesized by redox polymerization in 5~10% methanol aqueous solution using ammonium peroxodisulfate (APS) at 4 oC for 24h. The lower critical solution temperatures (LCSTs) of the comb-type grafted hydrogels were decreased with increase of t-BAM content in the grafted copolymer. We observed the effect of crosslinker and concentration of oligo(NIPAAm-co-t-BAM) on the shrinking/swelling ratio of hydrogels. Changes of shrinking/swelling ratio were decreased with increase of concentration of crosslinker. The increase of grafted oligo(NIPAAm-co-t-BAM) in the hydrogel shows an fast changes of shrinking/ swelling rate. The comb-type grafted hydrogels are expected to be valuable for the sensing materials of time-temperature labels(TTLs).

Potential Damage Region Investigation of WC-Co Cemented Carbide Die Based on Finite Element Analysis of Cold Forging Process (냉간 단조 공정의 유한 요소 해석에 기반한 WC-Co 초경 금형의 파손 위험 영역 평가)

  • Ryu, S.H.;Jung, S.H.;Jeong, H.Y.;Kim, K.I.;Cho, G.S.;Noh, W.
    • Transactions of Materials Processing
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    • v.31 no.6
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    • pp.376-383
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    • 2022
  • The potential damage region of a WC-Co cemented carbide die is investigated for cold forging process of a wheel-nut by numerical simulation with its chemical composition considered. Numerical simulation is utilized to calculate internal stress, especially for the WC-Co die, during the forging process. Finite element model is established, in which the elasto-plastic properties are applied to the work-piece of bulk steel, and elastic properties are considered for the lower die insert of the WC-Co alloy. This stress analysis enables to distinguish the potential damage regions of the WC-Co die. The regions from calculation are comparatively analyzed along with the crack area observed in the die after repetitive manufacturing. Effect of chemical composition of the WC-Co is also evaluated on characteristics of potential damage region of the die with variance of mechanical properties considered. Derived from Mohr-Coulomb fracture model, furthermore, a new stress index is presented and used for die stress analysis. This index inherently considers hydrostatic pressure and is then capable of deducing wide range of its distribution for representing stress state by modification of its parameter implying pressure sensitivity.

Evaluation of Heat Waves Predictability of Korean Integrated Model (한국형수치예보모델 KIM의 폭염 예측 성능 검증)

  • Jung, Jiyoung;Lee, Eun-Hee;Park, Hye-Jin
    • Atmosphere
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    • v.32 no.4
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    • pp.277-295
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    • 2022
  • The global weather prediction model, Korean Integrated Model (KIM), has been in operation since April 2020 by the Korea Meteorological Administration. This study assessed the performance of heat waves (HWs) in Korea in 2020. Case experiments during 2018-2020 were conducted to support the reliability of assessment, and the factors which affect predictability of the HWs were analyzed. Simulated expansion and retreat of the Tibetan High and North Pacific High during the 2020 HW had a good agreement with the analysis. However, the model showed significant cold biases in the maximum surface temperature. It was found that the temperature bias was highly related to underestimation of downward shortwave radiation at surface, which was linked to cloudiness. KIM tended to overestimate nighttime clouds that delayed the dissipation of cloud in the morning, which affected the shortage of downward solar radiation. The vertical profiles of temperature and moisture showed that cold bias and trapped moisture in the lower atmosphere produce favorable conditions for cloud formation over the Yellow Sea, which affected overestimation of cloud in downwind land. Sensitivity test was performed to reduce model bias, which was done by modulating moisture mixing parameter in the boundary layer scheme. Results indicated that the daytime temperature errors were reduced by increase in surface solar irradiance with enhanced cloud dissipation. This study suggested that not only the synoptic features but also the accuracy of low-level temperature and moisture condition played an important role in predicting the maximum temperature during the HWs in medium-range forecasts.

On the Design of Power Supply System for Freight Train Reefer Container Based on Simulation

  • Kim, Joouk;Hwang, Sunwoo;Lee, Jae-Bum;Hwang, Jaemin;Chae, Uri
    • International Journal of Internet, Broadcasting and Communication
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    • v.14 no.3
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    • pp.249-257
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    • 2022
  • In recent years, if we order food by easily accessing the online market with our smartphone, we can receive the product in a fresh state at dawn the next day. Cold chain is an industry that can create high added value because it has both the characteristics of general logistics and sensitivity to temperature. Based on the electrical specifications derived from the reefer container capacity requirement investigation, we proved that power supply to up to 33 reefer containers can be made by using three additional auxiliary power supplies which are applied for freight trains in Korea. In this paper, we conducted a research on a design of power supply system for freight train reefer container based on simulation as a basic research necessary for low-temperature distribution and cold chain construction based on the reefer container railroad. Consequently, the simulation was conducted using the three-phase inverter diagram in PSIM and the SVPWM (3-harmonic injection method) control technique, and it was verified that the required power voltage was satisfied with 622Vdc, which is lower than the input voltage of general SPWM of 718Vdc. The details of this paper could be used as a foundational study for constructing cold chains based on a reefer container dedicated to freight trains in the future.