• 한국작물학회지
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• 제35권4호
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• pp.352-361
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• 1990

동해안 랭조풍지대의 풍해 대표지역인 경북 영덕지방에서 1986년부터 1989년가지 4개년간 방풍강의 강목에 다른 풍해 경감효과와 농가포장 설치효과를 종합하면 다음과 같다. 1. 동해안 랭조풍지대의 1979년부터 1989년까지 11년간 태풍에 의한 백수 피해의 발생빈도는 8월 10일부터 9월 10일 사이에 높아 이 지역의 수도 안전출수한계기는 8월 10일 이전이 안전하다고 생각된다. 2. 이 지대는 태풍 통과시 증발계수가 250이상으로 높아 백수피해 위험도가 높으며 풍해를 유발시키는 바람의 종류는 태백산맥을 넘어오면서 휀(Fohn) 현상에 의한 고온건조한 편서풍과 해양에서 내륙으로부터 한랭과습한 랭조풍이었으며 도작기간중 발생빈도는 각각 25, 20%였다. 3. 방풍강 설치에 의한 풍속 감속효과는 방풍강의 강목이 좁을수록 컸으며, 방풍강이 설치된 지점으로부터 1m 거리에서는 23%, 10m 거리에서는 34%, 20m 거리에서는 28%였으며 그 효과는 설치된 방풍강 높이의 10배까지 있었다. 4. 방풍강 설치에 의한 기상개선효과는 무방풍구에 비해 방풍강의 강목이 좁을수록 컸으며 기온은 최고 0.8$^{\circ}C$, 최저 0.7$^{\circ}C$, 평균 0.6$^{\circ}C$ 상승되었고 수온은 최고 0.5$^{\circ}C$, 최저 0.6$^{\circ}C$, 평균 0.5$^{\circ}C$ 상승되었으며 지온도 0.4$^{\circ}C$ 상승되었다. 5. 방풍강에 의한 생육개선효과는 무방풍구에 비하여 방풍강의 강목이 좁을수록 컸으며 출수촉진, 개체군 생장속도 및 광이용율 증진, 간장신장, 주당수수, 수당영화수, 임실율, 천립중 등이 증가하여 방풍강의 강목(0.5$\times$0.5cm)에 따른 증수효과는 10%, 농가포장 설치효과는 15% 증수되었다. 6. 답면수온이 낮은 동해안 랭조풍지대에서는 주당묘수를 늘리는 것이 수수 확보에 유리하여 13% 증수효과가 있었으며 그 효과는 무방풍구에서 더욱 현저하였다. 7. 방풍강 설치에 의한 풍속 경감으로 동화기관의 고엽방지효과로 완전미의 비율이 높아 미질개선의 효과가 있었으며 벼알의 변색정도가 감소되었고 변색정도가 심할수록 증숙율과 천립중이 떨어졌으며 그 정도와 부의 상관관계가 있었다. 이상의 결과를 종합하면 태풍 발생빈도가 높은 동해안 랭조풍지대에서는 품종과 이앙기를 조절하여 풍해를 회피하거나 방풍림이나 방풍강을 설치하여 풍해를 경감시키는 것이 수량 생산의 안전성을 향상시킬 수 있을 것으로 생각된다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제49권5호
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• pp.262-269
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• 2023

Objectives: Anterior maxillary sinus wall fractures are common in all types of maxillofacial trauma. They can result in various complications, including injury to the surrounding nerves. Owing to its anatomy, trauma to the maxillary antrum can result in injury to the middle superior alveolar nerve (MSAN) and the anterior superior alveolar nerve (ASAN). The purpose of this study is to evaluate neurosensory deficits (NSD) present in maxillary gingiva, incisors, and premolars after injury to the anterior wall of the maxillary antrum. Materials and Methods: This prospective study was conducted among 39 patients sustaining unilateral fractures of the anterior maxillary sinus wall. Clinical neurosensory tests including two-point discrimination and fine touch discrimination were performed to classify the extent of nerve injuries as mild, moderate, severe, or anesthetic. Additional temperature discrimination and pulpal sensibility tests (electric pulp testing and cold testing) were carried out. A comparison of radiographic fracture patterns and severity of nerve injury was done. Testing was carried out immediately after trauma and at 2-month follow-up. Results: More than half of the patients assessed in the study group presented with NSD of the teeth and gingiva after trauma. The incidence of deficits varied with the type of test used to measure them. Most frequently, patients presented with both loss of two point as well as fine touch discrimination thresholds. Severe nerve injuries were associated with loss of temperature discrimination clinically and displaced fractures radiographically. There was no significant relationship between the recovery of pulpal and gingival sensation. The patterns of injury and recovery in ASAN and MSAN were similar. Conclusion: NSD after trauma to the maxillary antrum is relatively common. Clinical loss of temperature discrimination and radiographic signs of fracture lines passing through the canalis sinuosus are predictors of persistent and severe oral NSD.

• The Korean Journal of Pain
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• 제23권2호
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• pp.109-115
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• 2010

Background: The pathophysiological and neurochemical changes following spinal injury are not yet elucidated. This study was designed to evaluate the morphological changes of the dorsal horn of the spinal cord and profiles of pain behaviors following intraspinal injection of NMDA in rats. Methods: Rats were randomized into three groups: a sham-operated control group and groups where the rats received 10 mM or 100 mM N-methyl-D-aspatate (NMDA) injected into their spinal dorsal horn. Following injection, hypersensitivity to cold and mechanical stimuli and excessive grooming behaviors were assessed serially for four weeks. Morphological changes of the spinal cord were evaluated four weeks after intraspinal injection. Results: Few animals in the NMDA groups developed hypersensitivity to cold and mechanical stimuli. The number of groomers and the severity of excessive grooming were significantly higher in the 100 mM NMDA group than those values of the control and 10 mM NMDA groups. The size of the neck region (lamina III-IV) was significantly smaller in the 100 mM NMDA group than in the control and 10 mM NMDA groups. Conclusions: In conclusion, intraspinal injection of NMDA in rats leads to the pathological sequela in the spinal cord and to excessive grooming behavior. These results support the use of NMDA and excessive grooming behavior after excitotoxic SCI as a model to study chronic pain after SCI.

• 대한한의학원전학회지
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• 제36권2호
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• pp.61-75
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• 2023

Objectives : This study aims to examine the multi-layered meanings of Li Dongyuan's concept of 'internal damage' through examining the origins of the 'internal damage' concept together with discussions derived from his 'Differentiation of Internal and External Damage'. Methods : Rather than Li's original works, those done by later doctors who were influenced by Li were thoroughly examined in this study to determine the relationships among internal and external damage, and external contraction. Results : Based on discussions related to the 'differentiation of internal and external damage' following Li, his concept of 'internal damage' could be understood as multi-layered, as it contains both spatial as well as pathogenic meaning. Therefore the meaning behind categorizations of internal and external damage, and internal damage and external contraction could be different. Li's 'internal damage' concept includes not only internal pathogen but elements of external contraction of wind and cold, which seems to have been integrated into the 'Cold Damage Theory' after Zhu Danxi, seemingly having changed the concept of cold damage. Therefore, discussions on the crossing between internal damage and external contraction have on one hand expanded the boundaries of each concept, while on the other hand, have caused confusion between the two at times. Conclusions : The concept of 'internal damage' has been widely accepted due to Li Dongyuan, on which related discussions have been centered. However, the concept was originally multi-layered, naturally leading to various discussions. Future studies should focus on the relationship of 'internal damage' with 'external damage' or 'external contraction', beyond the theories of Li.

• Applied Biological Chemistry
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• 제38권3호
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• pp.212-217
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• 1995

내한성이 약한 유채(B. napus)와 내한성이 강한 산동채(B. campestris)를 공시하여 발아초기단계에서의 장기저온순화처리가 peroxidase와 superoxide dismutase 활성도 및 동위효소 pattern에 미치는 영향을 분석하여 작물 내한성 기작을 생화학적으로 구명함과 아울러 내한성 관련 genetic marker를 탐색하고자 본 연구를 수행하였다. 장기저온순화시킨 유묘를 저온처리후 24시간 회복시켰을 경우, peroxidase 활성도는 유채와 산동채의 뿌리부위에서 각각 157%와 50%, 배축부위에서는 201%와 250% 정도 크게 증가하였고, superoxide dismutase 역시 배축 및 뿌리부위에서 크게 활성화가 일어남을 관찰할 수 있었다. 또한 배축부위에서의 단백질 함량도 유채는 약 11.4%, 산동채는 57.4% 증가하였다. 장기저온순화처리로 새로 생합성된 peroxidase 동위 효소들중 특히 5번 band(pl 6.4)는 유채와 산동채의 뿌리부위에서 모두 출현될 뿐만 아니라 내한성이 강한 산동채의 배축부위에서도 강하게 출현되어 내한성 관련 genetic marker로써의 이용 가능성을 높여 주었다. 이상의 결과와 전보의 결과들을 종합적으로 고찰하여 저온 shock에 따른 분자산소의 생화학적 상호전환 모델을 제시하여 작물 내한성 기작을 생화학적으로 추론하였다.

• The Korean Journal of Pain
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• 제24권4호
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• pp.185-190
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• 2011

Background: Spinal nerve ligation (SNL) injury in rats produces a pain syndrome that includes mechanical and thermal allodynia. Previous studies have indicated that proinflammatory cytokines such as tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) play an important role in peripheral mediation of neuropathic pain, and that altered dorsal root ganglion (DRG) function and degree of DRG neuronal apoptosis are associated with spinal nerve injury. The present study was conducted to evaluate the expression of TNF-${\alpha}$ and the extent of apoptosis in the dorsal root ganglion after SNL in rats. Methods: Sprague-Dawley rats were subjected to SNL of the left L5 and L6 spinal nerves distal to the DRG and proximal to the formation of the sciatic nerve. At postoperative day 8, TNF-${\alpha}$ protein levels in the L5.6 DRG were compared between SNL and naive groups using ELISA. In addition, we compared the percentage of neurons injured in the DRG using immunostaining for apoptosis and localization of activated caspase-3. Results: SNL injury produced significant mechanical and cold allodynia throughout the 7-day experimental period. TNF-${\alpha}$ protein levels were increased in the DRG in rats that had undergone SNL ($12.7{\pm}3.2$ pg/100 ${\mu}g$, P < 0.001) when compared with naive rats ($4.1{\pm}1.4$ pg/100 ${\mu}g$). The percentage of neurons or satellite cells co-localized with activated caspase-3 were also significantly higher in rats with SNL than in naive rats (P < 0.001, P < 0.05, respectively). Conclusions: SNL injury produces mechanical and cold allodynia, as well as TNF-${\alpha}$ elevation and apoptosis in the DRG.

• 생물환경조절학회지
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• 제30권4호
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• pp.320-327
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• 2021

최근 지구온난화에 의한 이상기상으로 겨울철 한파와 봄철 저온에 의한 농작물 피해가 심각하게 발생하고 있다. 특히 과수의 개화기 저온피해는 꽃눈의 생육단계에 따라 차이가 있으며 발육이 진전될수록 내한성이 약해져 개화 직전부터 낙화 후 1주까지 한계온도가 다르게 발생한다. 따라서 개화기가 빠른 사과 '홍로'가 '후지'보다 피해가 심각한 것이 일반적이나 2020년 4월 저온피해는 개화기가 늦은 '후지'의 피해가 심하게 발생하여그 원인을 분석하고자 본 연구를 수행하였다. 충북 보은군 사과나무 '후지'와 '홍로'를 동시에 재배하는 2농가를 대상으로 품종 간 피해율 실태조사를 실시하였다. 또한 정확한 품종 간 비교 분석을 위하여 생육단계가 동일한 시료를 선택하여 인위적으로 저온처리(-2.0℃, -4.0℃)를 하여 피해 정도를 조사하고, 원인 분석을 위해 조직 내 유리당과 호르몬 함량을 분석하였다. 실태조사 결과 2농가 모두 '후지'가 '홍로'보다 피해율이 높았으며, 특히 B농가(저지대, 평지) '후지'의 경우 피해율이 60.5%로 가장 높았다. 또한 동일한 생육단계의 시료를 사용한 인위적 저온 처리 시험결과에서도 '후지'와 '홍로' 품종 간 피해율에 유의한 차이가 있었다. 유리당 함량은 저온 피해율이 낮았던 '홍로'가'후지'보다 높았으며, 호르몬 분석 결과 정상 꽃눈보다 손상된 조직에서 ABA, IAA와 SA 함량이 높게 나타났다. 따라서 본 연구 결과 조직내 유리당 함량이 높으면 저온 피해율이 낮은 것을 확인할 수 있었으며, 특히 저온 피해율은 sorbitol 함량과 부의 상관관계를 이루고 있다.

• 한국응용곤충학회지
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• 제53권4호
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• pp.355-365
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• 2014

배추좀나방(Plutella xylostella)이 국내에서 월동이 가능한 지 명확하지 않았다. 본 연구는 배추좀나방의 내한성에 기초한 야외 노출 실험을 실시하여 월동 환경 조건을 결정하고, 동계 야외 지역의 배추좀나방 유충 서식지 관찰 및 성페로몬을 이용한 성충 모니터링을 통해 월동이 가능한 지 조사하였다. 또한 이들 월동집단의 유래를 추적하기 위해 다형유전좌위를 이용한 집단 분석을 실시하였다. 배추좀나방의 체내빙결점 보다 높은 $-5^{\circ}C$로 처리한 결과 모든 미성숙 발육태에서 뚜렷한 생존력 저하를 보여 직접적 냉해 피해를 주었다. 여기서 유충발육태는 가장 낮은 냉해 피해를 받았다. 그러나 $5^{\circ}C$로 장기간(4 주) 처리한 결과 냉해 피해는 없었지만, 유충의 경우 먹이가 없는 상태에서 치사율이 증가했다. 모든 발육태의 배추좀나방을 대상으로 겨울 기간 동안 야외조건에 노출시킨 결과 모든 발육태에서 생존력 저하를 나타냈다. 그러나 비가온 실내조건에서 저온 피해를 줄였으며 유충의 경우 먹이가 공급되면 생존력이 뚜렷하게 증가하였다. 동계 성페로몬 모니터링 결과 2014년도 최초의 성충발생일은 유사한 시기에 서로 다른 지역(약 260 Km 거리)에서 나타났으며 월동집단의 성충은 4월 상순까지 포획되었다. 지역간 이들 월동집단의 유전적 거리는 다형분자마커를 이용하여 분석되었으며 이들 월동집단들 사이에 뚜렷한 유전적 분화가 있는 것을 나타냈다. 본 연구는 배추좀나방의 국내 월동이 남쪽 지역 또는 기주 식물이 있는 시설재배지에서 가능한 것으로 제시하고 있다.

• 대한화상학회지
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• 제24권2호
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• pp.21-29
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• 2021

Purpose: Frostbite is a hazard to people exposed to cold environments. With the progression of modern industrial development and change of leisure behavior encountering cold environments, frequent accidental exposure to frostbite injury during work and human behavior is increasing, and the predisposing factors of frostbite were greatly changed than before. The purpose of this study was to make epidemiological analysis, and to review the treatment outcomes of frostbite. Methods: From March 2010 to February 2021, this study has included 27 patients with second- to third-degree frostbite injuries in Advanced Burn Reconstruction Center, Bundang Jesaeng Hosptial. A retrospective study was made about the distribution of age, gender, predisposing factors, prevalent area, type of managements, and the length of treatment period. Results: In our institution, acute management of frostbite patients has included rewarming, anticoagulation therapy (acetylsalicylic acid), and agents to improve vascular perfusion (lipo-prostaglandin E1 [Eglandin^®]). The 25 frostbite patients with second-degree frostbite (92.6%) were successfully managed by the conservative treatment alone with a mean of 20.3 days healing time. Two patients with third-degree frostbite (7.4%) also showed good outcomes after surgical reconstruction with a mean of 59 days healing time. In our clinical experiences of third-degree frostbite, definitive surgical reconstruction should be recommended to wait for more than 4~6 weeks for identification of clear demarcation of necrotic tissue caused by frostbite. In this study, 43 frostbite injuries site in 27 frostbite patients occurred. Among them, 15 patients (55.6%) had multiple-site frostbite injury. The most common predisposing cause of frostbite was refrigerant gas accidents (44.4%), followed by outdoor activity in cold environments (40.8%), misapplying ice pack for treatment purposes (7.4%), barefoot walking on the cold ground (3.7%), and loss of consciousness in cold grounds (3.7%). The most prevalent sites of frostbite injuries revealed as the hand (58.1%), followed by the foot (32.6%), face (7.0%), and abdomen (2.3%). And in the winter season from the November to March, the incidence rate of frostbite injuries was high at 74.1%. Conclusion: This study included 27 frostbite patients with 43 frostbite sites since last decade in a single institution at the community hospital. The frostbite patients with second-degree frostbite (92.6%) were successfully healed by the conservative treatment alone with a mean of 20.3 days healing time. The most common predisposing cause of frostbite was refrigerant gas accidents (44.4%), followed by outdoor activity in cold environments, etc. The most prevalent site of frostbite injuries was the hand (58.1%). And the most prevalent seasonal incidence of frostbite was from November to March (74.1%).

• Journal of Chest Surgery
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• 제49권4호
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• pp.232-241
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• 2016

Background: Paraplegia is a devastating complication following operations on the thoracoabdominal aorta. We investigated whether histidine-tryptophan-ketoglutarate (HTK) solution could reduce the extent of ischemia/reperfusion (IR) spinal cord injuries in a rat model using a direct delivery method. Methods: Twenty-four Sprague-Dawley male rats were randomly divided into four groups. The sham group (n=6) underwent a sham operation, the IR group (n=6) underwent only an aortic occlusion, the saline infusion group (saline group, n=6) underwent an aortic occlusion and direct infusion of cold saline into the occluded aortic segment, and the HTK infusion group (HTK group, n=6) underwent an aortic occlusion and direct infusion of cold HTK solution into the occluded aortic segment. An IR spinal cord injury was induced by transabdominal clamping of the aorta distally to the left renal artery and proximally to the aortic bifurcation for 60 minutes. A neurological evaluation of locomotor function was performed using the modified Tarlov score after 48 hours of reperfusion. The spinal cord was harvested for histopathological and immunohistochemical examinations. Results: The spinal cord IR model using direct drug delivery in rats was highly reproducible. The Tarlov score was 4.0 in the sham group, $1.17{\pm}0.75$ in the IR group, $1.33{\pm}1.03$ in the saline group, and $2.67{\pm}0.81$ in the HTK group (p=0.04). The histopathological analysis of the HTK group showed reduced neuronal cell death. Conclusion: Direct infusion of cold HTK solution into the occluded aortic segment may reduce the extent of spinal cord injuries in an IR model in rats.