• Title/Summary/Keyword: cognitive significance

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Clinical Significance of Restless Legs Syndrome in Patients with Late Life Depression (노년기 우울증 환자의 하지불안증후군의 임상적 중요성)

  • Song, Jae Min;Park, Joon Hyuk;Kang, Ji Eon;Lee, Chang In
    • Korean Journal of Biological Psychiatry
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    • v.21 no.3
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    • pp.107-113
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    • 2014
  • Objectives Restless legs syndrome (RLS) is a sleep disorder characterized by uncomfortable and unpleasant sensations in the legs and an urge to move the legs, usually at night. The aim of this study is to investigate the incidence of RLS in patients with late life depression and its influence on various clinical outcomes such as severity of depression, sleep quality, cognitive function, and quality of life and accordingly, to elucidate the clinical significance of RLS in patients with late life depression (LLD). Methods This study enlisted 170 depressive patients aged 65 years or older from an outpatient clinic. Structured diagnostic interviews were performed using the Korean version of the Mini-International Neuropsychiatric Interview. All patients completed the questionnaires, including the International RLS Severity Scale, the Korean version of Short-Form 36-Item Health Survey (SF-36), and the Pittsburgh Sleep Quality Index (PSQI). The severity of depression was evaluated by the Korean form of the Geriatric Depression Scale (KGDS) and the level of global cognition was assessed by the Mini-Mental State Examination in the Korean version of The Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet (MMSE-KC). Results The incidence of RLS was 17.6% in LLD patients. RLS was more prevalent among the subjects with major depressive disorder (MDD) than those with minor depressive disorder or subsyndromal depressive disorder. The RLS group showed higher score in the KGDS than the Non-RLS group but the difference did not reach the statistical significance (p = 0.095, Student t-test). The mean PSQI score was significantly higher in the RLS group than in the Non-RLS group (p = 0.001, Student t-test). The MMSE-KC score was also lower in the RLS group than in Non-RLS group (p = 0.009, analysis of covariance). But, there was no difference in the score of SF-36 between the RLS group and the Non-RLS group. Conclusions RLS is common in LLD patients, especially in the patients with MDD and is associated with poor sleep quality and cognitive dysfunction, indicating that RLS is clinically significant in patients with LLD. Therefore, RLS should be considered as an important clinical issue in the management of LLD.

Correlation of the Neuropsychological Screening Battery (NSB) and Neuroanatomy for the Parkinson's Disease with Mild Cognitive Impairment by Using the Analysis of Cerebral Cortex Thickness in the Brain MRI (뇌 자기공명영상에서 대뇌 피질 두께 분석법을 이용한 파킨슨병의 경도인지장애 신경심리검사와 신경해부학적 상관관계)

  • Lee, Hyeonyong;Park, Hyonghu;Lee, Jaeseung;Im, Inchul
    • Journal of the Korean Society of Radiology
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    • v.8 no.4
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    • pp.163-170
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    • 2014
  • This study is to investigate neuro-anatomical correlation between neuropsychological results and cerebral cortex thickness of cognitive ability in the brain MRI targeting the patients with mild cognitive impairment. It was that 78 people who were diagnosed as first Parkinson's disease followed by neuropsychological screening battery(Parkinson's disease with mild cognitive impairment: 39 people; Parkinson's disease with normal cognition: 39 people) and 32 people of normal group were selected. Correlation between mild cognitive impairment and normal cognitive impairment and correlation between neuropsychological screening battery and cerebral cortex thickness in the brain MRI were performed by independent sample t-test or Pearson correlation coefficient and then level of significance of collected data was verified in p<0.05. As a result, cerebral cortex thickness of the Parkinson's disease with mild cognitive impairment in both side precuneas and right inferiortemporal lobe had statistically significant decrease. In addition, function of visuospatial ability, verbal and visual memory was reduced in neuropsychological screening battery for cognitive assessment. Especially, there was correlation between neuropsychological screening battery of verbal and visual memory anatomical left precuneus.

Understanding Information Culture: Conceptual and Implementation Issues

  • Oliver, Gillian
    • Journal of Information Science Theory and Practice
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    • v.5 no.1
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    • pp.6-14
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    • 2017
  • Information culture is a concept with multiple and sometimes conflicting definitions. Nevertheless at a time when social and cognitive aspects of information and communication systems are recognized as being of similar significance as the technological functionality, the concept of information culture is demonstrating considerable value. This paper explains the concept of information culture and considers its value from two main perspectives: firstly as providing an analytical tool, and secondly as a means of providing practitioners with insight and sensitivity to the organisational contexts of their workplaces.

Odontogenic Pain and Myofacial Pain: A Case Report (치성동통과 근막동통 : 증례보고)

  • 안은영;홍정표
    • Journal of Oral Medicine and Pain
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    • v.23 no.3
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    • pp.295-299
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    • 1998
  • Pain is a multidimensional experience that involves a complex interaction of sensory,affective and cognitive components. And especially, because of the emotional significance of orofacial pain, it is often a puzzing problem that clinicians are forced with from day to day. This case report describes differential diagnosis and management of dental and myofacial pain affected by psychological factors.

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The Relationship between Competition Anxiety and Performance Confidence in Amateur Baseball Player: The Moderated Mediation Effects of Cognitive Appraisal and Character Strength (아마추어 야구선수의 경쟁불안과 수행자신감과의 관계: 성격강점과 인지평가의 조절된 매개효과)

  • JinHee Son;SunYoung Park
    • The Korean Journal of Coaching Psychology
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    • v.7 no.3
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    • pp.197-225
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    • 2023
  • In this study, the impact of Competitive Anxiety on Cognitive Appraisal and Performance Confidence among Amateur baseball players was investigated, as well as the mediating role of Cognitive Appraisal in this relationship. Furthermore, the moderating effect of Character Strengths related to positive psychology on the relationship between Competitive Anxiety and Cognitive Appraisal was explored, dividing these Character Strengths into six virtues. To conduct this research, an online survey was administered to 201 Amateur baseball players aged 19 and above. The result of this study are as follows. First, it was found that the association between Performance Confidence and Competitive Anxiety is mediated by Cognitive Appraisal. Second, Character Strengths showed a moderating effect in the relationship between Cognitive Appraisal and Competitive Anxiety. Thirdly, statistical significance was shown for the moderated mediation effects. Specifically, it was established that values like Transcendence and Justice would considerably moderate the relationship. Notably, the degree to which Cognitive Appraisal declines as a result of Competitive Anxiety was found to be mitigated by Transcendence and Justice Character Strengths. In conclusion, based on the results of this study, implications, limitations were discussed.

Application and the Effect of Nutrition Education Program Based on the Social Cognitive Theory Among Middle School Girls (일부 여자 중학생 대상 사회인지이론기반 영양교육 프로그램의 적용 및 효과)

  • Kim, Jihea;Woo, Taejung;Lee, Kyoung Ae;Lee, Seung Min;Lee, Kyung-Hea
    • Korean Journal of Community Nutrition
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    • v.21 no.6
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    • pp.497-508
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    • 2016
  • Objectives: The purpose of this study was to evaluate the effect of nutrition education using materials based on social cognitive theory. Education topics focused on improving health-related and dietary self-awareness and behavior capability in adolescents. Methods: Participants were recruited from a middle school for girls; 67 students (educated group, n=34 and control group, n=33) participated. The education group received 12 lessons in club activity class. Self-administered surveys were conducted for each group before and after the nutrition education program. The questionnaires consisted of variables such as self-efficacy, outcome expectation, outcome expectancy, knowledge, and dietary practices based on the social cognitive theory. Education satisfaction was evaluated using a five-point Likert scale for two sections: a) teaching and learning and b) education results. The data were analyzed using a t-test and Chi Square-test (significance level: p < 0.05). Results: In the education group, post-education, there were significant differences in self-efficacy (p < 0.05), knowledge (p < 0.01), and dietary practices (p < 0.05), whereas outcome expectation and expectancy did not show any significant differences. None of the variables showed any significant differences in the control group. Educational satisfaction scores were $4.38{\pm}0.12$ (teaching and learning) and $4.14{\pm}0.15$ (education results). Conclusions: This study showed that improving adolescent's awareness and behavior capability has a positive effect on their dietary practices. Moreover, this study suggested that a theory-based determinant should be considered to improve dietary behavior among adolescents.

The Effects of One Year Exercise Program on Exercise Capacity & Cognitive Function in Male Patients with Dementia (1년간의 복합 운동프로그램이 남성 치매환자의 운동능력과 인지기능에 미치는 영향)

  • Kwak Yi-Sub;Um Sang-Yong
    • Journal of Life Science
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    • v.15 no.2 s.69
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    • pp.220-224
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    • 2005
  • The purpose of the present study is to investigate the effects of long-term exercise program on exercise capacity and cognitive function (MMSE) in male patients with dementia. 24 male patients were divided into two experimental groups : the exercise group (n=12) and the control group (n=12). The exercise group participated in regular exercise program for 12 months, and their exercise capacity (cardiopulmonary function, muscle strength, muscular endurance, flexibility, balance, agility) and MMSE (Mini-mental state examination) levels were evaluated at baseline (pre), after 6 months (mid) and after 12 months (post). The subjects carried on group-exercise of $VO_{2}max\;30\~60\%$, $30\~60$ minute a day, $2\~3$ times per week. Statistical techniques for data analysis was paired samples t-test. The level of statistical significance was ${\le}.05.$ The results of this study were summarized as follows: In the exercise group, there were significant differences in cardiopulmonary function, muscle strength, muscular endurance and MMSE at the times of pre & mid and pre & post, there were significant differences in balance and agility at the time of pre & post only, whereas there was no significant difference in flexibility following the long-term exercise. In the control group, there were no significant differences in all the times. Based on the results of this particular study, one year exercise program increases on the cognitive function & exercise capacity in male patients with dementia.

Whole Brain Radiation-Induced Cognitive Impairment: Pathophysiological Mechanisms and Therapeutic Targets

  • Lee, Yong-Woo;Cho, Hyung-Joon;Lee, Won-Hee;Sonntag, William E.
    • Biomolecules & Therapeutics
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    • v.20 no.4
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    • pp.357-370
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    • 2012
  • Radiation therapy, the most commonly used for the treatment of brain tumors, has been shown to be of major significance in tumor control and survival rate of brain tumor patients. About 200,000 patients with brain tumor are treated with either partial large field or whole brain radiation every year in the United States. The use of radiation therapy for treatment of brain tumors, however, may lead to devastating functional deficits in brain several months to years after treatment. In particular, whole brain radiation therapy results in a significant reduction in learning and memory in brain tumor patients as long-term consequences of treatment. Although a number of in vitro and in vivo studies have demonstrated the pathogenesis of radiation-mediated brain injury, the cellular and molecular mechanisms by which radiation induces damage to normal tissue in brain remain largely unknown. Therefore, this review focuses on the pathophysiological mechanisms of whole brain radiation-induced cognitive impairment and the identification of novel therapeutic targets. Specifically, we review the current knowledge about the effects of whole brain radiation on pro-oxidative and pro-inflammatory pathways, matrix metalloproteinases (MMPs)/tissue inhibitors of metalloproteinases (TIMPs) system and extracellular matrix (ECM), and physiological angiogenesis in brain. These studies may provide a foundation for defining a new cellular and molecular basis related to the etiology of cognitive impairment that occurs among patients in response to whole brain radiation therapy. It may also lead to new opportunities for therapeutic interventions for brain tumor patients who are undergoing whole brain radiation therapy.

Effects of the Forest Healing Program on Depression, Cognition, and the Autonomic Nervous System in the Elderly with Cognitive Decline

  • Lim, Young-suwn;Kim, Jaeuk;Khil, Taegyu;Yi, Jiyune;Kim, Dong-jun
    • Journal of People, Plants, and Environment
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    • v.24 no.1
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    • pp.107-117
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    • 2021
  • Background and objective: The purpose of this study is to investigate the effect of a forest healing program in terms of depression, neuropsychological and physiological benefits for the elderly. Methods: For this purpose, we developed a forest therapy program for the elderly who are vulnerable to dementia and conducted a total of 11 sessions of forest therapy activities in a forest once a week. We measured the changes in depression, resting-state Electroencephalography(EEG) and heart rate variability (HRV) before and after the program. There were 60 subjects aged over 65 yesrs old. 30 subjects participated in the forest therapy program, and the other were in the control group. The Geriatric Depression Scale was used to measure the level of depression, neuroNicle FX2 (Laxtha, Korea) was used to measure the resting-state EEG, and photoplethymogram (ubpulse T1, Laxtha, Korea) was used to measure the HRV. Results: The results showed that the depression index of the experimental group improved with statistical significance after the program (experiment group = 3.267 decrease of the mean). In the EEG measurement, the alpha-peak frequency at rest (experimental group = 0.227 Hz increase of the mean) was improved (mean increase = 0.23 in the experimental group, p < .05). The high frequency of HRV, which represents the parasympathetic nerve activity of the body's autonomous response, was also significantly improved (mean increase = 0.396 in the experimental group, p < .05). Conclusion: The results suggest that the forest therapy program can reduce the cognitive, psychological and physical risk factors of dementia for the elderly at risk of cognitive decline. Therefore, forest therapy activities may be suitable for the prevention of dementia in the elderly.

A study on the mother-infant intercation in teaching and feeding situation (모아상호작용에 관한 연구 - 교육과 수유상황을 중심으로)

  • Jo, Gyeol-Ja
    • The Korean Nurse
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    • v.29 no.5
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    • pp.54-68
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    • 1991
  • This study was conducted to provide the basic information for nursing intervention in infant teach. ing and feeding situation. The subjects were 30 pairs of mother and her infant(9 month) who were normally delivered at 3 university hospital in Seoul area. The data collection was conducted by observation using videotaperecord from September 27, 1989 to Feburary 26, 1990 in their home. The measulsement tools used by this researcher were Nursing child Assessment Teaching scale (NCATS) and Nursing child Assessment Feeding Scale(NCAFS) which was developed by Barnard. The higher sum of "yes" score means the higher mother-infant interaction level. Mother-Infant interaction behaviors in both sitution were based on 6 subcategories; sensitivity to cue, response to distress, social-emotional growth fostering, cognitive growth 'fostering, clarity of + cues, and responsiveness to parent. The data collected through above method were analyzed by mean and t-test and the results were as follows. 1. The sum of maternal behavior score was 40.2 out of 50.0 in teaching situation and 37.9 out of 50.0 in feeding situation. Out of the 4 subcategories on maternal behavior in both situation, the highest subcategory was shown by response to infant's distress and the lowest subcategory by cegnitive growth fostering. 2. The sum of infant behavior score was 14.7 out of 23 in teaching situation and 17.9 out of 26 in feeding situation. Out of the 2 categories on infant behavior in both situation, the highest sub categroy was shown by the clarity of infant's cue in both situation. 3. There was a statistical significance between father's educational level and mother-infant interaction in teaching situation; college group was higher than high school group, particulary in category of sensitivity to infant's cue and congnitive growth fostering. 4. There was a statistical significance in teaching situation between mother's educational level and mother-infant interaction;college group was higher than high school group, particulary sensitivity to infant cue, social-emotional growth fostering and cognitive fostering. 5. There was no statistical difference in between parent educational level and mother.infant interaction in feeding situation.situation.

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