• 대한약학회:학술대회논문집
• /
• 대한약학회 2005년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
• /
• pp.90-95
• /
• 2005

• Journal of Nutrition and Health
• /
• 제35권10호
• /
• pp.1070-1080
• /
• 2002

This study was designed to obtain the information concerning food intake, dietary habits, functional status, health condition and cognitive status of the elderly using public health center in Ulsan area. The subjects of this study consisted 154 elderly persons aged 60~82 years. Interviews were conducted using the health habits and food frequency questionnaires to provide basic information for nutrition education program. We evaluated the current food intake, dietary cholesterol intake (cholesterol index), functional status, cognitive function and blood analysis of the subjects. The results of this study were as follows : Mean age of the subjects was 68.7 $\pm$ 6.7years. The average cognitive status score of the subjects was 7.9 $\pm$ 2.0 (full score was 10.0). Male had a higher cognitive status score than female. There was significant difference between cognitive status score and age, education level, pocket money, physical activity and living condition. The subjects who had a higher cognitive status score ate more fish and meats group and milk and milk products than the subjects had a lower cognitive status score. And hemoglobin level, serum triglyceride, HDL-cholesterol and atherogenic index affected to cognitive status while fasting blood glucose and LDL-cholesterol did not any effect on cognitive status. These results have demonstrated that various socioeconomic variables and food intake pattern and nutritional status affect on cognitive status with aging and suggest that proper nutrition education and adequate nutrient intake in quality and quantity are essential in maintaining cognitive status in later life.

• Journal of Community Nutrition
• /
• 제5권3호
• /
• pp.173-177
• /
• 2003

This study was done to investigate the relationship of socioeconomic status and food intake to cognitive status of the older population. The subjects of this study consisted of 214 older persons aged 60 - 84 years. Interviews were conducted using the health-related habits and food frequency questionnaires to provide basic information for nutrition education program. We evaluated the current food consumption-pattern and cognitive status of the subjects. The results of this study were as follows： Mean age of the subjects was 69.7${\pm}$7.4 years. The average cognitive function score of the subjects was 7.9${\pm}$2.0 (full score was 10.0). Male had a higher cognitive status score than female. There was significant difference between cognitive status score and age, education level, pocket money, physical activity and family type. The subjects who had a higher cognitive status score ate more fish and meats group and milk and milk products than the subjects that had a lower cognitive status score. These results have demonstrated that various socioeconomic variables and food intake pattern affect on cognitive status with aging and suggest that proper nutrition education and adequate nutrient intake in quality and quantity are essential in maintaining cognitive status in later life.

• Osong Public Health and Research Perspectives
• /
• 제8권5호
• /
• pp.308-317
• /
• 2017

Objectives: We aimed to examine the effects of various leisure activities on cognitive impairment in young-old (aged 65-74 years) and old-old (aged ${\geq}75$ years) adults. Methods: In total, 10,279 elderly Korean individuals from the 2014 Korean National Survey on Older Adults' cohort were enrolled in our study. Cognitive impairment was assessed using the standardized score of the Mini-Mental State Examination for Dementia Screening, whereas leisure activities were recorded via self-reporting of the extent and type of leisure activity the subjects involved in over the past year. Multivariate logistic regression was used to assess the effect of leisure activities on cognitive impairment, while controlling for potential covariates. Results: The subjects were more likely to participate in cognitive activities than in non-exercise physical activities. After controlling for selected covariates, involvement in cognitive activities was found to be a significant predictor of cognitive impairment in both the groups, whereas involvement in non-exercise physical activities was not a predictor of cognitive impairment in individuals aged ${\geq}75$ years. Moreover, depressive symptoms, rural residence, and hearing difficulties were common predictors of cognitive impairment among elderly-Korean-individuals. Conclusion: Leisure activity involvement may help delay cognitive impairment, which is often concomitant with aging. Hence, an early intervention service may significantly benefit both young-old and old-old individuals.

• 대한지역사회작업치료학회지
• /
• 제9권2호
• /
• pp.13-22
• /
• 2019

목적 : 본 연구는 정상노화 과정에 따른 일화기억 저하 양상을 일화기억의 하위요소인 사물, 공간위치, 시간순서 기억을 중심으로 파악하고자 하였다. 연구방법 : 20대부터 80대 이상까지의 건강한 젊은 성인과 노인 77명이 본 연구에 참여하였으며, 일화기억을 평가하기 위한 컴퓨터 인지과제를 수행하였다. 인지과제는 사물, 공간위치, 시간순서 기억을 각각 평가하기 위한 세 가지 항목으로 구성되어 있었으며, 주변에서 흔하게 볼 수 있는 사진 10장을 이용하여 검사를 진행하였다. 사진 10장을 본 이후에 사진 속의 사물의 종류, 사물의 위치, 사진이 제시된 순서를 물어보는 과정을 통해 평가를 진행하였으며, 각 하위검사의 정답률을 연령대별로 분석하였다. 결과 : 연구 결과, 사물과 공간위치 기억은 정상노화에 큰 영향을 받지 않는 반면, 시간순서 기억은 정상노화 과정 속에서 큰 폭으로 저하되는 것을 알 수 있었다. 세부적으로 살펴보면 시간순서 기억은 40대 이상부터 20~30대에 비해 유의한 저하가 발생하는 것을 관찰할 수 있었고 80대 이후에는 사물 기억이 가장 높은 것으로 확인되었다. 즉 정상 노화 과정에 따라 시간순서 기억이 가장 먼저 감소되고 사물 기억이 가장 마지막에 저하되는 것을 확인하였다. 결론 : 본 연구는 정상노화 과정에 따른 일화기억의 하위요소별 저하 양상을 제시하였다. 사물 기억에 초점을 맞춘 기존의 신경심리학적 검사들을 통해 제한적으로 확인하였던 공간위치와 시간순서 기억의 저하 양상을 세부적으로 확인할 수 있었다. 본 연구 결과는 정상노화에 따른 일화기억의 저하에서 벗어난 일화기억의 손상을 선별하는데 도움이 될 것이며, 정상노인에게 시행되는 예방적인 인지 중재에 공간위치와 시간순서 기억의 훈련이 포함되어야 할 근거를 제시한다.

• 통합자연과학논문집
• /
• 제16권2호
• /
• pp.61-67
• /
• 2023

Human body ages differently due to environmental, genetic and pathological factors. DNA methylation patterns also differs depending on various factors such as aging and several other diseases. The aging clock model, which uses these differences to predict age, analyzes DNA methylation patterns, recognizes age-specific patterns, predicts age, and grasps the speed and degree of aging. Aging occurs in everyone and causes various problems such as deterioration of physical ability and complications. Alzheimer's disease is a disease associated with aging and the most common brain degenerative disease. This disease causes various cognitive functions disabilities such as dementia and impaired judgment to motor functions, making daily life impossible. It has been reported that the incidence and progression of this disease increase with aging, and that increased phosphorylation of Aβ and tau proteins, which are overexpressed in this disease and accelerates epigenetic aging. It has also been reported that DNA methylation is significantly increased in the hippocampus and entorhinal cortex of Alzheimer's disease patients. Therefore, we calculated the biological age using the Epi clock, a pan-tissue aging clock model, and confirmed that the epigenetic age of patients suffering from Alzheimer's disease is lower than their actual age. Also, it was confirmed to slow down aging.

• PNF and Movement
• /
• 제12권4호
• /
• pp.217-224
• /
• 2014

Purpose: The purpose of this study is to analyze the hand functions of elderly persons according to their cognitive status and age. Methods: A total of 65 persons voluntarily participated in the study. The subjects were divided into three groups: impairment cognitive group, normal cognitive group, adult group (persons in their twenties). Assessment of cognitive status was performed using a mini-mental state examination for Koreans (MMSE-K). Hand function was assessed using the Purdue pegboard test. The collected data were analyzed using a one-way ANOVA and Pearsonn Acorrelation. Results: There were significant differences in hand functions in the three groups. Post-hoc test results showed significant differences between each group. There were statistically significant differences in the correlation among hand functions, cognitive status, and age. The findings of this study suggest that hand functions have a positive correlation with cognitive status. However, a negative correlation was found between hand function and age. Conclusion: According to the study's results, hand functions are correlated with age and cognitive functions in elderly persons. This study suggests that hand rehabilitation with cognitive intervention increases hand functions in elderly persons.

• 한국노년학
• /
• 제39권4호
• /
• pp.801-824
• /
• 2019

현 고령화 사회로 치매에 대한 관심이 높아지고 있다. 하지만 치매예방에 대한 국가 차원의 프로그램이 미흡한 실정이다. 치매 예방 프로그램과 보급을 위해, 인지 기능 향상 프로그램을 실시하고 인지 기능 변별력, 구성력, 사고력, 기억력, 집중력으로 나누어 평가하여, 이러한 프로그램이 노인의 인지 기능에 구체적으로 어떤 영향을 미치는지 알아보고자 한다. 실버인지 건강 프로그램을 편성하고, 실험 군과 대조군을 모집해 3개월 동안 프로그램을 실시하고 실험 군과 대조군을 대상으로 MMSE-DS, 노인 우울척도, 인지영역테스트 실시하여 설문조사 방법을 통해 전후를 비교, 분석한다. 연구결과는 다음과 같다. 1. 프로그램 진행 전과 후의 인지 기능, MMSE-DS, 노인 우울척도를 비교한 결과 인지건강프로그램이 인지기능, MMSE-DS 및 노인우울척도 개선에 유의한 효과가 있었다. 2. 인지 기능을 5개 영역으로 나누어 테스트한 결과 기억력, 사고력, 집중력, 변별력, 구성력 순으로 향상되었다. 3. 인지건강 프로그램 실시 후 기억력과 사고력이 가장 많은 변화를 보였는데 뇌의 노화가 기억력과 사고력 부분에 많이 일어나므로, 이에 대한 집중적인 교육이 더 좋은 효과를 가져 올 수 있다.

• 가정과삶의질연구
• /
• 제21권2호
• /
• pp.145-154
• /
• 2003

As the life-expectancy is ever-increasing, and the proportion of the elderly population is growing steadily in every society of the world, it is ever more important to establish what factors allow certain elderly people to age successfully and remain relatively independent while others grow old less successfully and require extensive intervention. However, there is no consensus yet as to what successful aging means. Researchers have defined successful aging in a variety of ways. This study attempted to define the concept of successful aging and to clarify some dimensions of it through literature review. Previous approaches of studying successful aging and related themes were examined. Early perspectives including activity, disengagement, and continuity theories, Selective Optimization with Compensation (SOC) model by Baltes and Baltes, three different conceptions of successful aging, that is, psychological well-being, physical health, and wisdom, and MacArthur research on successful aging have been reviewed for this study. The definition derived from the review is: Keeping up continuous developmental processes to achieve wisdom or ego-integrity, without suffering any major disabilities in either physical or mental functioning, while maintaining psychological well-being and employing SOC strategies, and participating in positive relationships with significant others. The dimensions of successful aging are 1) personal resources, including physical health, cognitive competences, self esteem, and social support 2) adaptation process of SOC, and 3) psychological aspects, including psychological well-being and wisdom.

• 한국식생활문화학회지
• /
• 제17권3호
• /
• pp.289-298
• /
• 2002

This study was conducted to find sensitive indicator of food intake and specific food group related to cognitive function and to analyze the pathway among factors affecting food intake and cognitive function of the aged. 179 people over 50 years old were investigated and all the data were analyzed by SPSS 10.0 package. Food frequency was more sensitive indicator to show the relationship between food intake and cognitive function of the aged than the numbers of standard amount of food eaten. Consumption of grains and starch, meat, fish, eggs and beans were strongly related to cognitive function of the aged and intake of vegetables and fruits also have relationship with it. Moreover, the more frequent eating the carbohydrate and the protein, the higher the cognitive level of the aged. Age, education period, income, blood pressure, duration after retirement, frequency of physical activity and BMI were correlated with food intake and cognitive function of the aged. Among them, age and frequency of physical activity were most strongly correlated with food intake, and education period with cognitive function of them. This investigation shows that more stable intake of carbohydrate and protein containing foods need to be supplied to low income aged and the importance of physical activity of the aged must be emphasized with food intake for better life of the aged.