• 제목/요약/키워드: coefficient permeability

검색결과 613건 처리시간 0.032초

Franz Diffusion Cell을 이용한 인진호 함유 경피제의 피부투과 특성 연구 (Permeation Characteristics of Transdermal Preparations Containing Artemisiae Capillaris Herba in Franz Diffusion Cell)

  • 김은남;박교현;김배환;정길생
    • 생약학회지
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    • 제49권2호
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    • pp.165-171
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    • 2018
  • Artemisiae Capillaris Herba is a dried aerial part of Asteraceae capillaris Thunb.(Compositae), which has been used in Korean traditional medicine for the treatment of various diseases. It has a variety of pharmacological activities and has been evaluated for potential as an active ingredient in cosmeceutical products. In the cosmetics industry, animal experiments is besides the major concern of ethics, there are few more disadvantages of animal experimentation like demand of skilled manpower, time consuming protocols and high cost. Therefore, various alternatives to animal experiments have been proposed. The purpose of this study was to investigate the skin permeation characteristics of chlorogenic acid and dimethyleculetin, which are constituent of Artemisiae Capillaris Herba by using Franz diffusion cell. As a result, skin permeability was characterized by flux(penetration rates) and $K_p$(permeability coefficient) value, chlorogenic acid had lower flux and $K_p$ than dimethylesculetin. According to the definitions of Marzulli, chlorogenic acid and dimethylesculetin would be classified as 'Moderate' and 'Very fast' respectively. In conclusion, skin permeation characteristics of chlorogenic acid and dimethylesculetin were confirmed through Franz diffusion cell, and suggests the direction of alternative method for skin permeation of natural compounds.

변성 셀룰로오즈 막내의 물의 상태 (The State of Water in Modified Cellulose Membranes)

  • 이순홍;이영무;김진일;김재진
    • 공업화학
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    • 제4권1호
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    • pp.125-131
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    • 1993
  • 두 종류의 변성 셀룰로오즈 막내의 물의 상태를 시차열분석계를 이용하여 분석하였다. 셀룰로오즈막들은 카르복시메틸 셀룰로오즈(CMC)-젤라틴 고분자전해질 복합체막과 아크릴산 가교 메틸셀룰로오즈(MC)전해질막이다. 동결수(자유수)와 비동결수(결합수) 양을 측정하여서 막을 통한 용질들의 투과도와의 관계를 조사하였다. 막내의 물의 상태는 막의 조성, 모폴로지, 그리고 수화도의 영향을 받는 것을 알았다. 수화된 막들을 통한 확산 투과도의 차이를 자유수와 결합수의 차이로 설명하였다.

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Soil-Bentonite 혼합토의 강도 특성 (Strength Characteristics of Soil-Bentonite Mixture)

  • 김광일;신동훈;임은상;김기영
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2009년도 춘계 학술발표회
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    • pp.844-851
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    • 2009
  • A soil mixture with low permeability and bentonite as an additive has been highly utilized as a cutoff material in landfills, banks, and dams. Even though it is anticipated that the water can seep through shear failures in the filter layer due to external loads and embankment loads during construction, usually only the coefficient of permeability of the soil mixture is considered rather than the changes of strength from the different amounts of additives. Therefore, the amount of bentonite was changed between 0%~4% in the soil mixture of the bed material to conduct a series of unconfined compressive strength, tensile strength, and shear strength tests on a specimen in order to study the characteristics of the strength. In the result, the unconfined compressive and tensile strength were increased along with the increased amount of bentonite in the low water content; however, the tensile strength in the consolidated-drained shear test generally showed similar values without significant changes.

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아스팔트순환골재를 이용한 투수성 콘크리트의 역학적 특성 (The Mechanical Properties of Porous Concrete using Recycled Asphalt Aggregate)

  • 이동욱;윤중만;김남식;강영민
    • 한국지반신소재학회논문집
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    • 제10권1호
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    • pp.37-42
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    • 2011
  • 본 연구에서는 아스팔트순환골재를 이용한 투수성 콘크리트의 역학적 특성을 알아보기 위하여 투수성 콘크리트의 단위시멘트량, 잔골재 비율, 물시멘트(w/c)비의 혼합율 변화에 따른 역학적 특성과 구조체로서 요구되는 소요강도에 대하여 분석하고자 하였다. 순환골재의 사용성을 높이기 위하여 입도조정 없이 13mm 아스팔트순환골재를 사용하였으며, 물시멘트비는 빈배합이 되도록 결정하였다. 분석결과 압축강도는 18.2~19.5Mpa을 보였으며 투수계수는 평균적으로 8.0E-02cm/sec 값을 나타내었다.

계측관리를 통한 방조제 바닥보호공의 침투거동분석 (Analysis of Seepage Behavior of Bottom Protection Layer by Filed Monitoring)

  • 강병윤;오영인;김기년;김현태
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2008년도 추계 학술발표회
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    • pp.806-813
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    • 2008
  • In this research, mainly research about the structural and functional stability of sea dyke with variation of seepage condition after final closure. The piezometric head (water head in embankment) monitoring system was installed at two representative final closure section. The dredged fine sand filling condition was evaluated by in-situ test results. Also, the numerical analysis was performed to determine the permeability of bottom protection layer filled with dredged fine sand by monitoring results. According to numerical back analysis results, the coefficient of permeability of bottom protection section of is $7.6{\times}10^{-6}$ m/sec. These results are noted that the bottom protection layer of sea dyke was strong and intensively filled with dredged sand. Also, based on the seepage analysis, the seepage flux of this sea dyke was calculated about $2.42m^3$/day/m which is 29% decreased value compare with adjacent sea dyke.

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Mathematical simulation of surfactant flushing process to remediate diesel contaminated sand column

  • Asadollahfardi, Gholamreza;Darban, Ahmad Khodadadi;Noorifar, Nazila;Rezaee, Milad
    • Advances in environmental research
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    • 제5권4호
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    • pp.213-224
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    • 2016
  • This paper presents a numerical model based on a UTCHEM simulator to simulate surfactant flushing process to remediate diesel contaminated sand column. For this purpose, we modeled remediation process under 10000 and 20000 ppm initial concentrations of diesel. Various percent-mass sodium dodecyl sulfate (SDS) considered in our model. The model results indicated that 0.3 percent-mass of SDS at 10000 ppm and 0.1 percent-mass of SDS at 20000 ppm initial diesel concentration had maximum removal perdition which is in agreement with the experiment results. For 10000 ppm diesel concentrations, the coefficient of determination ($R^2$) and index of agreement (IA) between the model result and the experimental data were 0.9952 and 0.9695, respectively, and for 20000 ppm diesel concentrations, $R^2$ and IA were 0.9977 and 0.9935, respectively. The sensitivity analysis of permeability illustrated that in all diesel concentrations and SDS percent-mass with increasing permeability the model resulted in more removal efficiency.

Boron removal from model water by RO and NF membranes characterized using S-K model

  • Kheriji, Jamel;Tabassi, Dorra;Bejaoui, Imen;Hamrouni, Bechir
    • Membrane and Water Treatment
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    • 제7권3호
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    • pp.193-207
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    • 2016
  • Boron is one of the most problematic inorganic pollutants and is difficult to remove in water. Strict standards have been imposed for boron content in water because of their high toxicity at high concentrations. Technologies using membrane processes such as reverse osmosis (RO) and nanofiltration (NF) have increasingly been employed in many industrial sectors. In this work, removal of boron from model water solutions was investigated using polyamide reverse osmosis and nanofiltration membranes. RO-AG, RO-SG, NF-90 and NF-HL membranes were used to reduce the boron from model water at different operational conditions. To understand the boron separation properties a characterization of the four membranes was performed by determining the pure water permeability, surface charge and molecular weight cut-off. Thereafter, the effect of feed pressure, concentration, ionic strength, nature of ions in solution and pH on the rejection of boron were studied. The rejection of boron can reach up to 90% for the three membranes AG, SG and NF-90 at pH = 11. The Spiegler-Kedem model was applied to experimental results to determine the reflection coefficient of the membrane ${\sigma}$ and the solute permeability $P_s$.

구체방수 콘크리트의 균열 자가치유 성능 (Self-Healing Performance of Concrete Using Admixture)

  • 이종윤;이한주;이용진
    • 한국안전학회지
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    • 제27권6호
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    • pp.109-114
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    • 2012
  • This study is the things to experiment and evaluate the performance of self-healing water-proofing on the concrete to be using the crystal growth composite waterproofing admixture. The cylinder to be making on the concrete by ${\varnothing}150{\times}300$ mm for evaluating the performance of self-healing water-proofing was aging 90 days and cut on a 50 mm. So, it prompted the crack and applied. After it measured the quantity of water to be flow the water throughout the crack part of the cylinder, it applied the basic formular of Darcy's law and calculated the coefficient of water permeability. So, it verified the performance of self-healing water-proofing on the basis of the changing shape of the water permeability. This experiment is the thing to be applied the general evaluation of the structure to demand the real watertightness on doing for the evaluating of performance of the quantity of water leak and self-healing water-proofing about the various penetration crack.

실리콘이 라미네이팅된 신축성 소재의 위생 및 안전성과 역학적 성능 (Analysis of Physical Performance, Hygiene and Safety of Silicone-Laminated Stretch Material)

  • 권명숙;정기수
    • 한국의류학회지
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    • 제31권1호
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    • pp.77-84
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    • 2007
  • The purpose of this study was to investigate and to compare the performances of silicone laminated materials sold for swimming cap in market, to get the basic data for product development. We selected 4 specimens and tested their air permeability, waterproofness and breathability. We also tested the physical and mechanical properties of the specimens using KES system. Silicone-laminated material was not bursted on high hydraulic pressure since silicone membrane gave waterproofness while PU/Polyester substrate gave elasticity. It didn't have air permeability and breathability at all. Any toxic materials such as Formaldehyde, Deldrin, PCP, Amin, TDBPP were not detected in silicone-laminated material and other materials. Silicone-laminated material had higher stretchability with the low force but it had lower elastic recovery and shape stability comparing to PU laminated material. It had lower flexibility than PU laminated material. It had lower unrecoverable amount in shearing direction. Friction coefficient was higher in silicone-laminated material than PU laminated material due to its surface stickiness. It was compressed easily and its compression resiliency was higher with compared to PU laminated material.

A Study for the Viscous Flow of Sodium Chloride Through a Cuprophane Membrane

  • Jee Jong-Gi;Kwun Oh Cheun;Jhon Mu Shik;Ree Taikyue
    • Bulletin of the Korean Chemical Society
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    • 제3권1호
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    • pp.23-30
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    • 1982
  • For the study of transport phenomena of an aqueous NaCl solution through a cuprophane membrane, a new apparatus was constructed. The volumc flow rate Q, the permeability coefficient U, and the permeability constant K were measured or determined by using this apparatus. The experimental temperature range was 5 to $35^{\circ}C$, and the applied pressure increments were 10 to 40 psi. By assuming that the cuprophane membrane is composed of n parallel cylindrical capillaries of circular cross-section and that the flow of the solution through the capillaries follows the Poiseulle law, the mean radius r of the capillaries and the number n of the latter in the membrane were evaluated. By using a reasonable assumption concerning the radius ${\eta}'$ of the species diffusing through the membrane, it was concluded that the contribution of the diffusive flow to the total flow rate Q is less than 10%. Thus, the Q was treated as the rate due to the viscous flow, and the viscosity ${\eta}_m$ of the solution in the membrane phase was evaluted, and it was found that ηm is nearly equal to ${\eta}_b$, the bulk viscosity of the solution. From this fact, it was concluded that in the capillaries, no change occurs in the physical state of the NaCl solution. The value of ( = 4.27 kcal/mole) and ${\Delta}Sm^{\neq}$(4.28 eu) were obtained for the viscous flow. A possible explanation was given.