• Title/Summary/Keyword: clinical status

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Trends of clinical trials from 2014 to 2016 in South Korea

  • Huh, Ki Young;Hwang, Jun Gi;Lee, SeungHwan
    • Translational and Clinical Pharmacology
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    • v.26 no.4
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    • pp.172-176
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    • 2018
  • Mandatory registration of clinical trials in public registry can ensure the transparency of clinical trials. Public clinical trial registry of can provide current chronological and geographical distribution of clinical trial throughout the country. We used public clinical trial registry provided by Ministry of Food and Drug Safety to analyze current status of clinical trial from 2014 to 2016 in South Korea. The number of clinical trials in antineoplastic and immunomodulating agents area was the greatest, followed by cardiovascular system and antiinfectives for systemic use as a whole. From 2014 to 2016, overall number of clinical trials decreased while the number of phase I clinical trials increased. Seoul accounted for more than half number of clinical trials in Korea. Supports for clinical trials in non-metropolitan area needs to be considered.

The Effect of Initial Cognitive Status on the Recovery of Functional Status in Patients with Subacute Stroke (초기 인지상태가 아급성기 뇌졸중 환자의 기능상태 회복에 미치는 영향)

  • Hong, Jeong-Min;Kim, Min-Hee
    • PNF and Movement
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    • v.19 no.3
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    • pp.351-359
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    • 2021
  • Purpose: This purpose of this study was to investigate the effects of initial cognitive status on the recovery of functional status in patients with subacute stroke. Methods: The participants were 111 patients with subacute stroke, divided into two groups: mini-mental state examination (MMSE) <20 (n=49) group and MMSE ≥20 (n=62) group. Clinical evaluation scores were collected before and after rehabilitation. The repeated measurements ANOVA was used to confirm the changes in functional status before and after intervention in the two groups. Changes in functional status within the group were examined through a paired test. A Pearson correlation coefficient analysis was performed to identify the correlation between MMSE change amount and functional status score. Results: In each of the two groups, according to the initial cognitive status, the clinical evaluation score increased statistically significantly, but there was no difference between the two groups in the degree of significant increase. When examining the correlation between the MMSE change amount, according to the initial cognitive state and the functional state score change amount, it was found, only in the group with MMSE <20, that the larger the change in the MMSE score, the greater the functional state change of Berg balance scale, Rivermead Mobility Index, and motor assessment scale. This did not apply to the group with MMSE ≥20. Conclusion: Initial cognitive status should be considered when setting the patient's goal, and considering cognitive improvement when constructing a rehabilitation program is thought to have a positive effect on rehabilitation services.

Changes in health status of North Korean children and emerging health challenges of North Korean refugee children

  • Choi, Seong-Woo
    • Clinical and Experimental Pediatrics
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    • v.64 no.11
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    • pp.552-558
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    • 2021
  • The food shortage in North Korea is a serious situation that has spanned the mid-1990s to today. North Korean refugee children, even those born in North Korea, China, or South Korea, had poor nutritional status at birth; thus, their growth and nutritional status should be continuously monitored. This review focused on the health status of North Korean children and the nutritional status of North Korean refugee children upon settling in South Korea. Immediately after entering South Korea, North Korean refugee children were shorter and lighter than South Korean children and had a serious nutritional status. Over time, their nutrition status improved, but they remained shorter and lighter than South Korean children. A new obesity problem was also observed. Therefore, it is necessary to continuously monitor their growth and nutritional status.

Analysis of Participation Status in Clinical Nursing Education and Needs for Continuing Education among Clinical Nurses according to Hospital Type (의료기관 종별 간호사의 임상간호교육 참여 현황과 보수교육 요구 분석)

  • Shin, Sujin;Hwang, Eunhee;Kang, Youngmi;Oh, Hyunjoo
    • Journal of East-West Nursing Research
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    • v.26 no.2
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    • pp.196-204
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    • 2020
  • Purpose: This study investigates the participation status in clinical nursing education and nurses' continuing education needs to develop educational programs. Methods: Participants were 227 nurses working in medical institutions where nursing students practiced, and the selection criteria were nurses with more than two years of clinical education experience; data were collected using structured questionnaires. Results: More than half of the clinical nurses had completed a preceptor training program for clinical nursing education, and the subjects mainly educated by nurses were new graduate nurses and nursing students. The obstacles to clinical nursing education were lack of compensation, lack of manpower, lack of patient nursing time, excessive workload, and lack of knowledge as educators. The educational methods preferred in continuing education were small-group workshops and online education. The desired educational topics in continuing education were current nursing practice standards, simulation nursing education, and the role of clinical nursing educators. Conclusion: Based on our results, it is necessary to understand the importance of clinical nursing education, which is essential for clinical nurses, to prepare a specific system for them and to develop and operate a systematic education program according to medical institutions' characteristics.

Current Status and Future Direction of Nursing Education for Clinical Practice (간호학 임상실습교육의 현황과 발전방안)

  • Shin, Sujin;Yang, Eunbae B.;Hwang, Eunhee;Kim, Konhee;Kim, Yunju;Jung, Dukyoo
    • Korean Medical Education Review
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    • v.19 no.2
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    • pp.76-82
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    • 2017
  • The quantitative expansion of nursing schools has necessitated the qualitative improvement of nursing education, which requires the development of nursing education for clinical practice. To identify strategies for strengthening the educational capacity of clinical fields and nursing schools, this study first examined the current status of nursing education for clinical practice, and then proposed several prospective directions for education. Nursing clinical practice-related studies from several Korean and international electronic databases were reviewed. Insufficient training hospitals and lack of qualified clinical training instructors were the main problems found within nursing educational resources for clinical practice, while the simple practice contents based on observation and inadequate evaluations were the main problems found in nursing educational management for clinical practice. This study suggests better standards and educational accountability for training hospitals and programs to nurture human resources for clinical practice, as well as a variety of training methods to integrate practical training courses and the expansion of formation evaluation. Based on these results, it is necessary to establish governance for nursing education for clinical practice and clarify the role and standards of each practitioner, strengthen the educational role of the hospital, and improve the system. In addition, introducing various types of education methods and strengthening evaluation standards are needed in order to enhance nursing education for clinical practice.

Survey of Korean Medicine Military Doctors for Establishing Clinical Evidence of Korean Medicine Treatment in Military Medical Service (군진 한의학 근거 기반 구축을 위한 한의군의관 진료 현황 및 인식 조사 연구)

  • Kwon, O-Jin;Kim, Eun-Jung;Eom, Yu-Sik;Park, Sang-Min;Kim, Dongsu;Park, Hyo-Ju;Kim, Joo-Hee
    • The Journal of Korean Medicine
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    • v.38 no.3
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    • pp.73-85
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    • 2017
  • Objectives: The purpose of this study was to investigate the status of Korean medicine treatment, and to analyze problems and demands to provide basic data on Korean medicine in military medical services. Methods: This survey was completed by 30 volunteer Korean medicine military doctors on service via a web-based questionnaire system. The questionnaire was developed through in-depth interviews with Korean medicine military doctors and consisted of general information on the subject, overall characteristics of the medical environment, current status of Korean medicine care in each workplace, problems and needs, and related clinical evidence and education. Results: Korean medicine military doctors administered acupuncture treatment most frequently in clinical practice. The most common complaints were related to musculoskeletal diseases, which accounted for 86.5% of all diseases, including those of the respiratory, digestive, and nervous systems. Most of the problems in Korean medicine care were pointed out as being due to a lack of awareness of Korean medicine in the military. Many doctors were aware that it is necessary to establish clinical evidence for Korean medicine in the military, and were also positive about the possibility of performing clinical research in the military, but the experience of actual participation in clinical research or related education was uncommon. Conclusions: Korean medicine military treatment differs from private medical care due to the specificity of each workplace and the military medical system. In the future, it will be necessary to establish an appropriate Korean medicine treatment model in the military suitable for these characteristics and strategic plans for clinical evidence.

Influence of Nurses' Critical Thinking Disposition and Self-Leadership on Clinical Competency in Medium Sized Hospitals (중소병원 간호사의 비판적 사고성향과 셀프리더십이 임상수행능력에 미치는 영향)

  • Lee, Sun Hwa;Lee, Eun Ja
    • Journal of Korean Clinical Nursing Research
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    • v.24 no.3
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    • pp.336-346
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    • 2018
  • Purpose: This study was conducted to identify nurses'critical thinking disposition, self-leadership and clinical competency in small to medium sized hospitals less than 300beds. Methods: Data were collected using the questionnaire from 227 nurses in Incheon city and Gyeonggi province from March to April, 2017. The data were analyzed using t-test, ANOVA and $Scheff{\acute{e}}^{\prime}s$ test to identify differences in critical thinking disposition, self-leadership and clinical competency. Pearson correlation coefficients were used to identify the correlation among the study variables, and multiple regression was used to identify factors contributing to clinical competency. Results: There were significant differences in critical thinking disposition according to age, marital status, clinical career, career in currently working department and education about leadership. Significant differences in self-leadership were identified according to marital status, work position, working department, work type, education about leadership, and turnover intention. Clinical competency was significantly different depending on age, education, monthly income, work position, career in currently working department, work type, education about critical thinking disposition and education about leadership. Clinical competency was positively correlated critical thinking disposition and self-leadership. Critical thinking deposition, monthly income and self-leadership explained 30.1% of clinical competency of nurses working in small to medium sized hospitals. Conclusion: The results of this study suggest that we need to improve nurses'critical thinking disposition, self-leadership, and the clinical competency.

Dietary Life, Vitamin D Status and Blood Clinical Indices of University Laboratory Workers (대학 연구활동종사자의 식생활실태, 비타민 D 영양상태 및 혈액 임상지표 분석)

  • Hwang, Jung Hyun;Lee, Hong Mie;Kim, Jung Hee
    • Korean Journal of Community Nutrition
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    • v.24 no.3
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    • pp.245-256
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    • 2019
  • Objectives: Although the number of laboratory workers is constantly increasing every year, few studies have been conducted on the health and nutritional status of these research workers. This study determined the health status of laboratory workers by analyzing their anthropometric indices, dietary life, vitamin D status and blood clinical indices. Methods: The subjects consisted of 100 female laboratory workers. This study investigated their diet, anthropometric indices, vitamin D status and blood clinical indices. The subjects were divided into two groups according to their duration of working in a laboratory (<1 year, $${\geq}_-1year$$). Results: The average age and body mass index (BMI) of subjects were 23.18 years and $21.51kg/m^2$, respectively Those subjects with over 1 year employment ($${\geq}_-1year$$) had a significantly higher waist-hip ratio than that of the subjects with the less than 1 year employment (<1 year). The mean serum vitamin D level of all the subjects was 10.04 ng/mL, which is close to a level of vitamin D deficiency. There was a significantly higher average intake of calories in the over 1 year employment group as compared to that of the less than 1 year employment group. The frequency of eating sweet snacks was significantly higher for the over 1 year employment group. The correlation analysis showed a significant positive correlation between the serum 25-(OH)-vitamin D level and the time of exposure to sunlight, while dietary intake of vitamin D did not show correlation with the serum 25-(OH)-vitamin D level. However, the serum 25-(OH)-vitamin D level was also negatively correlated with both the percentage of body fat and visceral fat. Conclusions: Laboratory workers are a very high risk group in terms of their nutritional status of vitamin D. Therefore, they need greater time of exposure to sunlight as well as increasing their dietary consumption of vitamin D. In addition, it is important for laboratory worker to practice regular and balanced dietary habits in order to maintain a healthy life.

Myoclonic status epilepticus in hypoxic ischemic encephalopathy which recurred after somatosensory evoked potential testing

  • Kim, Seongheon;Kim, Yeshin;Kim, Sunghun;Lee, Seo-Young
    • Annals of Clinical Neurophysiology
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    • v.19 no.2
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    • pp.136-140
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    • 2017
  • A 77-year-old male with amyotrophic lateral sclerosis had a hypoxic event. After resuscitation, generalized myoclonus appeared and resolved after two days. Five days after the hypoxic event, myoclonic seizures re-emerged right after performing a somatosensory evoked potential and persisted for ten days. Electroencephalogram revealed frequent bi-hemispheric synchronous spike and waves in the central areas. We suggest that somatosensory evoked potential testing may trigger myoclonic status epilepticus. Underlying cortical degeneration associated with amyotrophic lateral sclerosis could attribute to this phenomenon.

Cefepime-induced nonconvulsive status epilepticus in a hemodialysis patient

  • Lee, Yoo Jin;Park, Bong Soo;Park, Kang Min;Kim, Il Hwan;Park, Jin Han;Park, Si Hyung;Kim, Yang Wook
    • Annals of Clinical Neurophysiology
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    • v.20 no.2
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    • pp.97-100
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    • 2018
  • Nonconvulsive status epilepticus (NCSE) is an unusual complication in patients treated with cefepime. An 82-year-old woman on maintenance hemodialysis was given cefepime for pneumonia. Her level of consciousness decreased since the administration of cefepime, and she was diagnosed with NCSE based on electroencephalography (EEG) findings. After discontinuation of cefepime, improvement was seen both in the level of consciousness and EEG findings. Clinicians should be aware of cefepime-induced NCSE, particularly in patients with renal failure.