• Annals of Clinical Neurophysiology
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• 제1권1호
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• pp.47-54
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• 1999

The Doppler in neurosonologic examination could be applied to blood flow to determine its movement, the direction of its movement, and how fast it is. Indicies of the Doppler study denoted velocity, direction, and amount of RBC in the examined vessel. Systolic. diastolic, and mean blood flow velocities represent velocity of RBCs in a sample volume. Blood flow direction to the probe means direction of RBC to the probe. Size of amplitude displays toe amount of the RBCs passing the sample volume. Spectral broadening means presence of turbelence. The RBC movements and hemodynamics at the examined vessels can be estimated by analysis of Doppler indicies The formation and meaning of each of neurosonologic Doppler study is described in the present review.

• Journal of the Korean Statistical Society
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• 제32권1호
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• pp.33-46
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• 2003

The continual reassessment method (CRM) provides a Bayesian estimation of the maximum tolerated dose (MTD) in phase I clinical trials. The CRM has been proposed as an alternative design of the standard design. The CRM has been modified to improve practical feasibility and, recently, the likelihood approach CRM has been proposed. In this paper we investigate the consistency and asymptotic normality of the modified likelihood approach CRM in which the maximum likelihood estimate is used instead of the posterior mean. Small-sample properties of the consistency is examined using complete enumeration. Both the asymptotic results and their small-sample properties show that the modified CRML outperforms the standard design.

• 한국간호교육학회지
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• 제4권2호
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• pp.317-330
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• 1998

A descriptive-explanatory design was employed in this study. The purpose of this study was identify the level of assertiveness and clinical stress and the relationships between assertiveness and clinical stress in nursing students. A convenient sample of 143 nursing students was used for the study. The results of this study are as follows : 1) The level of assertiveness of nursing students was 3.65 in domain of contents, 3.68 in domain of voice, and 4.13 in domain of body language. Thus the level of asertiveness of nursing students was higher in body language. 2) The level of clinical stress of nursing students was 3.73 in domain of clinical education and evaluation by professors, 3.59 in domain of nurses, 3.32 in domain of human relationships, and 3.30 in domain of environment. Thus the level of clinical stress of nursing students was higher in clinical education and evaluation by professors. 3) The assertiveness of nursing students was found significantly related to human relationships. 4) The clinical stress of nursing students was found significantly related to satisfaction of nursing, satisfaction of clinical practice and priority of candidate for nursing. 5) The assertiveness of nursing students was not found significantly related to clinical stress in nursing students.

• 대한약침학회지
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• 제8권2호
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• pp.47-52
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• 2005

Objectives : This study was performed to examine effects of herbal acupuncture therapy on shoulder pain. Methods : Control group were treated by common acupuncture therapy and sample group were treated by common acupuncture therapy and herbal acupuncture therapy. We compared control group with sample group by VAS and ROM. Results : VAS of sample group were more decreased than control group. ROM of sample group were more improved than control group. Conclusion : The herbal acupuncture therapy may be good effects on the shoulder pain.

• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2733-2737
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• 2014

Objective: Molecular pathology tests are often carried for clinicopathological diagnosis and pathologists have established large collections of formalin-fixed, paraffin-embedded tissue (FFPE) banks. However, extraction of DNA from FFPE is a laborious and challenging for researchers in clinical laboratories. The aim of this study was to compare two widely used DNA extraction methods: using a QIAamp DNA FFPE kit from Qiagen and a Cobas Sample Preparation Kit from Roche, and evaluated the effect of the DNA quality on molecular diagnostics. Methods: DNA from FFPE non-small cell lung carcinoma tissues including biopsy and surgical specimens was extracted with both QIAamp DNA FFPE and Cobas Sample Preparation Kits and EGFR mutations of non-small cell lung carcinomas were detected by real-time quantitative PCR using the extracted DNA. Results and Conclusion: Our results showed that DNA extracted by QIAamp and Cobas methods were both suitable to detect downstream EGFR mutation in surgical specimens. Howover, Cobas method could yield more DNA from biopsy specimens, and gain much better EGFR mutation results.

• 한국간호교육학회지
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• 제15권1호
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• pp.72-80
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• 2009

Purpose: This study was designed to identify the prediction factors that influence nurses' organizational commitment. Method: The sample of this study consisted of 526 full-time nurses randomly picked at 19 general hospitals in Korea. The data was analyzed by computer using SPSS 15.0 for Pearson's correlation coefficient, and multiple regression analysis. Result: 1) According to general characteristics, nurses' organizational commitment levels among the sample were significantly different in age, religion, social status, marital status, clinical career, and department satisfaction. 2) Level of nurses' organizational commitment was average 2.70, job satisfaction 2.91, burnout 3.03, empowerment 3.36, autonomy 2.93, and self-efficacy 3.51. 3) Nurses' organizational commitment had significant positive correlations with job satisfaction, empowerment, self-regulation, social support, self-efficacy, clinical career, and personnel movement experience. On the other hand, it had significant negative correlations with occupational stress, burnout, and age. 4) The prediction factors which influence Nurses' organizational commitment were job satisfaction($\beta$=.405), burnout($\beta$=-.282), self-regulation($\beta$=.171), clinical career($\beta$=.135). These factors were approximately 49.6% reliable in explaining nurses' organizational commitment. Conclusion: These results can be used to develop hospitals' management strategies for increasing organizational commitment effectiveness and nursing productivity.

• 대한임상검사과학회지
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• 제44권3호
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• pp.124-127
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• 2012

Syphilis is an infectious and sexually transmitted chronic disease caused by Treponema pallidum. On the basis of clinical findings, the disease has been divided into a series of overlapping stages, which are used to help guide treatment and follow-up. Persons who have syphilis might seek treatment for signs or symptoms of primary infection, secondary infection and tertiary infection. Latent infections are detected by serologic testing. A presumptive diagnosis of syphilis is possible with the use of two types of serologic tests: nontreponemal tests and treponemal tests assay. The use of only one type of serologic test is insufficient for diagnosis, because each type of test has limitations, including the possibility of false-positive test results in persons without syphilis. KFDA published Koreans guideline of Sexually transmitted infections in 2011. Two hundred samples were tested by RPR card test and Mediace RPR test with simultaneously. The agreement between RPR card test and Mediace RPR test was 95%, the discrepant samples was 5%. The characteristics of 10 discrepant samples was RPR card Positive and Mediace RPR negative nine samples, RPR card negative and Mediace RPR positive one sample. The nine samples were confirmed as FTA-ABS by KFDA guideline of syphilis test algorism, all IgM test was Negative, all IgG test was reactive. So, these cases were past or latent syphilis. The one sample was false-positive reaction.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3785-3788
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• 2014

Purpose: To explore the clinical characteristics of bone metastasis (BM) in a large sample of preliminarily diagnosed nasopharyngeal carcinomas (NPCs). Methods: The sample consisted of 1,031 patients diagnosed with NPC at first visitg clinics between October 1989 and June 2012. Several parameters including metastasis locus, T/N staging, diagnosis, therapy and prognosis of BM were analyzed retrospectively. Results: In 70 patients who had been preliminarily diagnosed with BM, the incidence of BM in N0, N1, N2 and N3 stage was 5.7%, 17.2%, 50.2%, and 25.7%, respectively, while the incidence in T0, T1, T2 and T3 stage was 0%, 23.8%, 47.6% and 28.6% respectively. BM occurred in most common in vertebral column, rib, sternum, ilium and femur. Positive rate of Epstein-Barr virus antibody was 77.6%. The median survival time was 12 months. Conclusion: The incidence of BM in NPC preliminarily diagnosed is about 7% and it is related to N classification but not T classification.

• Journal of Acupuncture Research
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• 제18권2호
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• pp.175-185
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• 2001

Objectives : In order to study the effect of taping therapy on the activity of daily living of poststroke-hemiplegic patients, a clinical study was performed. Methods : Twenty patients with poststroke-hemiplegia were randomized into two groups. Ten patients treated with kinesio taping. The other ten patients didn't treat with kinesio taping. Tapes were applied to the Deltoid, Supraspinatus, Infraspinatus, Brachioradialis, Gluteus Maximus, Adductor muscles of the hip, Sartorius and Tibialis Anterior. The activity of daily living was measured with a modifted barthel index(MBI). The taping therapy was performed twice a week for 2 weeks. Results : In terms of improvement of activity of daily living, the smaple group showed statistically meningful increase after 2 times treatment compared with control group(p<0.05). In terms of self care score of MBI, the sample group showed statistically meningful increase after 1 time treatment with the control group(p<0.05). In terms of mobility score of MBI, the sample group showed statistically meningful increase after 3 times treatment with the control group(p<0.05). Conclusions : These results support that taping therapy is significantly effective in improvement of the activity of daily living of poststroke-hemiplegic patients.

• Restorative Dentistry and Endodontics
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• 제41권3호
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• pp.231-234
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• 2016