• Korean Medical Education Review
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• v.14 no.2
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• pp.102-108
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• 2012

This study developed a test entitled Clinical Critical Thinking Skills (CCTS) by using item response theory (IRT) and examined its validity. In the development stage, data obtained from a convenience sample of 627 undergraduate nursing students were analyzed using a discrimination and difficulty index with the TestAn 1.0 program. In the evaluation stage, data from a convenience sample of 284 nursing and non-nursing students were analyzed using a discrimination and difficulty index with the BILOG-MG program. Criterion validity was verified by the group comparison method. Five items received low discrimination index scores according to the IRT results. In terms of the criterion validity, CCTS scores differed according to major (t=2.21, p=0.028), location of high school (F=4.35, p=0.014), clinical experience (t=5.66, p=0.004), and grade point average (F=7.17, p< 0.001). The CCTS can be used to measure critical thinking skills in the clinical setting.

• Journal of Korean Clinical Nursing Research
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• v.20 no.3
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• pp.372-383
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• 2014

Purpose: The purpose was to determine the content validity of a semantic revision of items on a reliable and valid instrument, the Sieloff-King Assessment of Group Outcome Attainment (Power) within Organizations in Korea (K-SKAGOAO). Methods: The target population for research was chief nurse officers (CNOs) of all hospital within Korea. A sample of 303 hospitals from across the Korea was selected through a stratified random sampling process. A total of 174 CNOs comprised the final sample. Psychometric evaluation of the K-SKAGOAO included: (a) criterion-related validity (b) factor analysis and (c) internal consistency reliability using Cronbach's alpha coefficients. Results: The Convergent validity and criterion-related validity were supported. Cronbach's alpha coefficient for the K-SKAGOAO was .95. Subscale alphas ranged from .60 to .86. Conclusion: The K-SKAGOAO and related subscales show validity and internal reliability. A nursing group of any size can use the K-SKAGOAO to both assess the group's level of outcome attainment and develop strategies to further improve that level.

• Proceedings of the KOSOMBE Conference
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• v.1992 no.05
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• pp.118-120
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• 1992

We have developed and been using laboratory order communication system which is a computerized laboratory request and reception system wi th bar code between inpatient or outpatient and the clinical laboratory in Chungbuk National Unversity Hospital. Work flows are as follows: Tests are requested by the physicians through hospital information system without issuing request forms. Bar code stickers containing demographics of patient and other informations such as sample number, slip code and specimen code are printed and attached to smaple tubes. At the department of clinical pathology, smaples are received through the bar code reader. Area numbers are automatically created and laboratory work numbers are determined. Worklists can be issued by each section of laboratory when needed. Our order communication system alleviates the human labor such as specimen labelling and making worklist and reduces clerical errors that occur from sample collection to laboratory analysis.

• Korean Journal of Clinical Laboratory Science
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• v.43 no.4
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• pp.133-137
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• 2011

The monitoring of heparin therapy is using almost aPTT assay. This study is compare to estimating aPTT therapeutic range using in vitro heparin-spiked sample and aPTT therapeutic range using in vivo heparin-treated sample. Normal pooled plasma was collected from 20 healthy representative individuals. 11 concentration of heparinized plasmas from 0 U/mL to 1.0 U/mL at intervals of 0.1 U/mL made by addition of heparin to normal pooled plasma were measured aPTT. The aPTT therapeutic range was performed through correlation analysis between heparin level 0.2 to 0.4 U/mL and aPTT. 30 plasmas from patients on heparin therapy were measured aPTT and anti-Xa activity. The aPTT therapeutic range was performed through correlation analysis between anti-Xa activity 0.3 to 0.7 U/mL and aPTT. The aPTT therapeutic range corresponded by heparin level-vs-aPTT value regression analysis was 60.7 to 102.4 seconds. The aPTT therapeutic range corresponded by anti-Xa activity-vs-aPTT value regression analysis was 85.3 to 147.5 seconds. The validation of heparin sensitivity using in-vitro heparin sample was not considered. The establishing aPTT therapeutic range is recommended anti-Xa activity using in-vivo sample.

• Korean Journal of Biological Psychiatry
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• v.19 no.4
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• pp.153-158
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• 2012

Understanding of a clinical trial is essential in developing clinical guideline and adopting evidence based practice. In designing and executing clinical trials, following ethical requirements should be considered : social value, scientific validity, fair subject selection, informed consent, favorable risk-benefit ratio, institutional review board, and respect for human subjects. According to the stage of drug development, purpose of trials, accumulated scientific data, clinical trials for drug development are classified as phase 1, 2, 3, and 4. Phases of clinical trials can be overlapped and the judgment of entering into the next phase should be considered highly strategically. In reading, evaluating and interpreting clinical trial reports, various skills and challenges exist. Patient sample composition, trial duration, selection of endpoints, responders and non-responders, placebo effect, patient recruitment, and extrapolation to the real world are the examples of those challenges. Treatment success will come from the well balanced approach of evidence based decision making and consideration of specific single case.

• Proceedings of the Korean Statistical Society Conference
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• 2002.11a
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• pp.79-83
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• 2002

A phase III clinical trial of a new drug for neutropenia induced by chemotherapy is presented and consider adding random effects in crossover design which was used in the clinical study. The diagnostics for its heteroscedasticity based on score statistic is derived for detecting homoscedasticity of errors in crossover design. A small simulation study is peformed to investigate the finite sample behaviour of the test statistic which is known to have an asymptotic chi-square distribution under the null hypothesis.

• Quality Improvement in Health Care
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• v.7 no.2
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• pp.168-179
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• 2000

Background : Economic evaluation of clinical pharmacokinetic consultation services for theophylline, which is being widely used recently, is considered in patients for both proper care and cost efficiency. Mathods : This is a cost-benefit analysis of clinical pharmacokinetic consultation service for theophylline. Trial groups were chosen from 2 general hospitals which was performing clinical pharmacokinetic consultation- services in 1998. Control group was chosen from another one general hospital. The analysis includes 25 patients (sample patients) for trial group and 17 patients for control group. Results : On the basis of incremental analysis, it is estimated that the total (direct and indirect) annual costs of the clinical, pharmacokinetic services of theophylline for the patients in the trial group was about \65 million, whereas total annual benefits from those services was estimated to be about \551 million. The net benefits incurred to the sample patients, thus calculated, was about \485 million per year. In the analysis, we assumed that indirect benefits accruing to those services were non-existent. If that amount was included, the estimated net benefits would be much greater than the calculated one. Conclusion : We found that clinical pharmacokinetic consultation services for theophylline could produce more marginal benefits than marginal costs by those services from the social point of view. More controlled prospective trial in the future would be helpful for affirmation of the results of this study.

• Journal of Preventive Medicine and Public Health
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• v.15 no.1
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• pp.111-114
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• 1982

To determine Pb level in blood, we usually .used to pull out about 5ml blood from venous vessel and this sample was digested with acids to decompose organic matter and then determined the Pb contents by Atomic Absorption Spectrophotometer with flame. But recent trend in quan titating Pb in small amount of sample is very much recommended in clinical chemistry specially pediatrics, and industrial hygiene and occupational health area. Authors tried to determine Pb contents in small amount blood of $25{\mu}l$ by using capillary tube method and got the possibility of determination of ng amount of Pb in $25{\mu}l$ whole blood sample without any pretreatment of sample.

• Korean Journal of Clinical Laboratory Science
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• v.52 no.3
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• pp.261-270
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• 2020

This study reviewed the quality addition rate, calculation, and application criteria needed to identify the possibility of additional medical technologists in the field for new certification and professional manpower to provide a superior laboratory. The six institutions that participated in the study were the size of large hospitals with more than 1,000 beds, with an average of five full-time laboratory physicians (also called clinical pathologists) and an average of 53 medical technologists, with 10.6 per laboratory physician. An analysis of the time required for each activity category of medical technologists revealed decreasing behavior during the analysis. In contrast, the ratio of the comprehensive pre-analysis activities was high due to the strengthening of laboratory operations and quality control. During the analysis, the proportion of biochemistry tests was high, and post-analysis of most of the results was performed. Hence, improving the quality of sample testing requires significant time, and appropriate personnel are required. In conclusion, the recruitment of medical technologists is also a key component to improving the sample quality, and corresponding personnel regulations are necessary.

• Journal of radiological science and technology
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• v.22 no.1
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• pp.79-85
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• 1999

This is an exploratory study to describe clinical demonstration patterns assessment and training-related problems(TRP) in Korea. A probability sample was drawn from Nation-Wide area by a multi-stage cluster sampling. This study in radiotechnological students of college over two years from 1997. Clinical demonstration patterns in this study involve a fundamental concept of radiotechnological students, a general notion of clinical demonstration, a rates of satisfaction in clinical demonstration, clinical demonstration patterns assessment, and training-related problems(TRP). High prevalence rates of clinical demonstration were found in male, students over twenty-four years old, those who perform at least hospital in college of medicine.