• 동의생리병리학회지
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• 제25권6호
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• pp.1044-1049
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• 2011

The purpose of this study was to study clinical characteristics of patients complained of tremor and to evaluate availability of oriental medical treatment. This observation was made on 36 cases that were hospitalized in the Semyung University Oriental Medicine Hospital and evaluated tremor using clinical rating tremor scale(CRTS). The ratio of patients were essential tremor(50%), parkinson's disease(13.9%), psychogenic tremor(13.9%), physiologic tremor(11.1%), cerebellar tremor(11.1%). CRTS score of essential tremor patients decreased significantly. Physiologic tremor patients's CRTS score were under 15 points. Every patient's scores decreased. Two patients's score decreased to 0 point. Every patient were treated with Bojungikki-tang-gamibang. CRTS scores of psychogenic tremor patients were various.(4~24 points) Two patients's scores decreased to 0 point. The CRTS scores of three cases among four patients with cerebellar tremor were not changed. Changes of CRTS score between oriental medication group and western-oriental combined medication group were statistically significant. Changes of CRTS score between over 15 points group and under 15 points group were statistically significant. Kejigayongolmoryo-tang was one of the most widely used herbal medication, which was diagnosed as ascendant hyperactivity of liver yang.

• 대한한방내과학회지
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• 제42권5호
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• pp.1102-1108
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• 2021

Objective: This report describes the case of a patient with essential tremors of the mouth and hands, which were improved by Yeokhan-san treatment. Methods: To relieve the symptoms, Korean medicine treatments, including Yeokhan-san, Ohaeng-Hwa acupuncture, and electronic moxibustion, were performed. To evaluate the effects of the treatments, the visual analog scale and Fahn-Tolosa-Marin clinical rating scale for tremor were used. Results: After the treatment, the patient's clinical symptoms were improved. The visual analog scale score decreased from 10 to 2 for the hand tremor and from 10 to 1 for the mouth tremor. The Fahn-Tolosa-Marin tremor scores decreased from 3 to 1 for both the hand and mouth tremors. Conclusions: The present case suggests that Yeokhan-san and Ohaeng-Hwa acupuncture are effective for the treatment of essential tremor.

• 대한한방내과학회지
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• 제42권2호
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• pp.152-164
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• 2021

Objective: This case reports on the effect of traditional Korean medicine (TKM) treatment in a patient with psychogenic dystonia. Methods: A patient with generalized tremor and gait disturbance diagnosed as psychogenic dystonia was treated with Yokukan-san-gami, Jakyakgamcho-tang, Yikgeebohyul-tang, acupuncture, moxibustion, and cupping for 6 weeks. Symptom improvement was evaluated with the unified dystonia rating scale (UDRS) and the Toronto Western spasmodic torticollis rating scale (TWSTRS). Results: After 6 weeks of TKM treatment, the UDRS and TWSTRS decreased, and the patient's clinical symptoms, including generalized tremor and gait disturbance, improved. Conclusions: This case shows that TKM treatment may be effective for improving psychogenic dystonia.

• 동의신경정신과학회지
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• 제28권2호
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• pp.95-107
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• 2017

Objectives: This study was performed to review studies on Essential Tremor (ET) in Traditional Chinese medicine (TCM). Methods: We reviewed papers in the China National Knowledge Infrastructure (CNKI) from 2007~2016. Search keywords were 原发性震颤, 特发性震颤, essential tremor and idiopathic tremor, and excluded non-clinical studies, non-related to ET or TCM studies, theses for degrees and non-Randomized Controlled Trial (RCT). The quality of the articles was assessed by Jadad scale and the Risk of Bias (RoB). Results: Thirteen studies were selected. 'Criteria for the diagnosis of ET' was most frequently used as diagnostic criteria. 'Tremor rating scale' was primarily used for outcome measurement. Meta-analysis of nine trials revealed the effective rate of acupuncture and Western medicine (WM+Acu) groups was significantly higher compared to the WM group (RR: 1.48, 95 percent CI: 1.20 to 1.82, p=0.0002, $I^2=0$ percent) and tremor rating scale was also significantly decreased in the treatment group (MD: -1.35, 95 percent CI: -2.17 to -0.54, p=0.001, $I^2=0$ percent). Also, effective rates of Electro-acupuncture (EA) and Chinese herbal medicine (CHM) groups were significantly higher than that of the WM group {(RR: 1.53, 95 percent CI: 1.22 to 1.92, p=0.0003, $I^2=0$ percent) in EA vs. WM and (RR: 1.35, 95 percent CI: 1.16 to 1.57, p<0.0001, $I^2=0$ percent) in CHM vs. WM}. However, the quality of selected clinical studies was poor. Conclusions: Treatment of ET in TCM may be more effective and safe than in Western medicine. Therefore, we hope this study will lead to further clinical research on treatment of ET in Korean medicine.

• 대한한방내과학회지
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• 제37권4호
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• pp.653-660
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• 2016

Objectives: The purpose of this study was to investigate the effects of Korean medicine on patients with idiopathic Parkinson’s disease.Methods: The charts of 47 patients diagnosed with idiopathic Parkinson’s disease in the Department of Internal Korean medicine, Stroke and Neurological Disorders Center, Kyung Hee University Hospital, Gangdong between August 2012 and July 2016 were reviewed. The Unified Parkinson’s disease rating scale (UPDRS) was administered before and after treatment with Korean medicine.Results: Thee average UPDRS Ⅱ+Ⅲ, UPDRS Ⅱ, and UPDRS Ⅲ of the 47 patients decreased significantly from 22.26±15.15, 10.19±7.53, and 12.06±8.35, respectively, pretreatment to 16.96±13.63, 7.47±6.44, and 9.49±7.73, respectively, post-treatment. The average postural instability and gait difficulty (PIGD), tremor, and bradykinesia also significantly improved post-treatment.Conclusions: These results provide evidence that Korean medicine can improve the activities of daily living and motor function of patients with idiopathic Parkinson’s disease. In particular, Korean medicine may be effective for the treatment of PIGD, tremor, and bradykinesia.

• 사상체질의학회지
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• 제28권2호
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• pp.193-204
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• 2016

Objectives This case study is about a Taeeumin patient with advanced Parkinson's disease identified as Dry-heat (Joyeol) pattern. In this study, we report significant improvement of non-motor and motor symptoms after treatment with Cheongsimyeonja-tang.Methods The patient was identified as Taeeumin Dry-heat (Joyeol) pattern and treated with Cheongsimyeonja-tang and acupuncture. The Unified Parkinson Disease Rating Scale (UPDRS) was used to assess the overall functions of the patient. And the global assessment scale (GAS) was used to assess the improvements of dizziness, bradykinesia and tremor after the treatment.Result and Conclusion The UPDRS total score decreased from 138 points to 86 points after 5 weeks treatment. And symptoms of dizziness caused by hypotension, bradykinesia, and tremor showed significant improvement in GAS after the treatment. Furthermore, sleep disturbance and constipation were reported to be improved after the treatment. In conclusion, this study shows that Sasang constitutional medicine can be effective treatment for Taeeumin patient with advanced Parkinson's disease having orthostatic hypotension.

• 사상체질의학회지
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• 제26권2호
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• pp.194-204
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• 2014

Objectives The aim of this study was to examine significant improvement of gait ataxia, vertigo and tremor after treatment with Sipyimigwanjung-tang, Hyangsayangwi-tang in a Soeumin Greater Yin Symptomatology patient Diagnosed as Cerebellar ataxia. Methods The patient was diagnosed with Soeumin Greater Yin Symptomatology and treated with Soeumin's constitutional medications and acupuncture. The primary outcome measures for this study were the Unified Multiple System Atrophy Rating Scale(UMSARS) and Cerebellar function test to assess the overall function of patient. Secondary outcome assessment included Global Assessment Scale(GAS), change of patient's sleep, stool and digestion. Results The symptoms of gait ataxia, vertigo and tremor decreased from GAS 100 to GAS 0~40 after treatment, and the UMSARS score decreased in Part I, II. Conclusions This case showed that Sasang Constitutional medicine treatment can be effective treatment method for cerebellar ataxia. We consider that consistent treatment can contribute to improve the patient's quality of life.

• 사상체질의학회지
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• 제29권4호
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• pp.376-386
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• 2017

Objectives This case study is about a Taeeumin patient with Parkinson's disease identified as Dry-heat (Joyeol) pattern. In this study, we report significant improvement of motor and non-motor symptoms of this patient after Sasang constitutional medicine treatment. Methods The patient was identified as Taeeumin Dry-heat pattern and treated with Cheongsimyeonja-tang and acupuncture. The Unified Parkinson Disease Rating Scale(UPDRS) was used to assess the overall function of the patient. And the Global Assessment Scale (GAS) was used to assess the change of bradykinesia, tremor and dry mouth after the treatment. Results The UPDRS total score decreased from 145 points to 77 points after 5 weeks treatment. And symptoms of bradykinesia, tremor and dry mouth showed significant improvement in GAS after the treatment. Furthermore, constipation, sleep disturbance, dysuresia and anorexia were reported to be improved after treatment. Conclusions This study shows that Sasang constitutional medicine can be effective treatment for motor and non-motor symptoms caused by Parkinson's disease.

• Annals of Clinical Neurophysiology
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• 제11권1호
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• pp.9-15
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• 2009

Background: To investigate the differences of locomotor dynamics between Parkinson's disease (PD) patients with tremor dominant symptom and patients with postural instability dominant symptom. Methods: 66 subjects with PD were classified into two subgroups, tremor-dominant group and postural instability and gait disorder group by Unified Parkinson's disease rating scale (UPDRS). The spatial, temporal and electrodynamic gait parameters were recorded automatically using computerized 3-D motion analysis system with electrogoniometer. Results: There was no significant difference in cadence, pelvic tilt range, hip flexion range, knee flexion range and ankle dorsiflexion range. Postural instability and gait disorder group showed decreased gait velocity, short stride length, decreased range of motion in pelvic obliquity, pelvic rotation and ankle plantar flexion. Conclusions: There was meaningful difference in locomotor dynamics between Parkinson's disease(PD) patients with tremor dominant symptom and patients with postural instability dominant symptom.

• 대한의용생체공학회:의공학회지
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• 제35권4호
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• pp.81-86
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• 2014

One of the methods for Parkinson's disease(PD) tremor evaluation is the Clinical Tremor Rating Scale(CTRS). However, the method has some limitations that clinician ratings can vary because the scores are subjectively rated. In addition, most researches usually collected data measured on the more affected arm. In this study, we developed a portable wearable system(SNUMAP system) for measuring PD tremor. The SNUMAP system captures 3-dimensional motion using tri-accelerometer and tri-gyroscope on finger and wrist. 40 PD patients participated in resting tremor and postural tremor tasks, while wearing the system on both hands simultaneously. Estimated tremor scores from Leave-One-Out Cross Validation for regression were highly correlated to the average clinician CTRS scores for rest tremor($r^2$ = 0.87, RMSE = 0.48) and postural tremor($r^2$ = 0.82, RMSE = 0.48). Therefore, the quantitative assessment model can improve treatment of PD patients.