• 대한예방한의학회지
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• 제4권2호
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• pp.25-56
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• 2000

Trace element are involved in enzymatic activities, immunological reactions. physiological mechanisms. Deficiency in some trace elements, such as iron and iodine. is still an important health problem, The role of trace elements deficiency is suspected in various clinical situations and is now confirmed by well designed supplementation studies. However, the importance of trace elements as chinese herbal constituents is not sufficiently appreciated by the oriental medical profession, although in recent years a significant increase of new finding on their essential character in chinese herbal medicine occurred. It is well known that herbal medicine contains a variety of trace elements which would show therapeutic effects with active components in herbal medicine . In china, recent work showed some positive correlation between trace element and traditional chinese medicine (TCM) in terms of therapeutic effects even if their role in therapeutic effects is still obscure. In korea, not much attention has been on the therapeutic importance of trace element contained in herbal medicine Here, the therapeutic effects of trace element in TCM were reviewed and summarized. 1. Iron, copper, zinc and manganese are mainly contained in TCM. In addtion, chromium, magnesium, molybdenum, nickel, alminium, cobalt, arsenic and selenium has been studied for their therapeutic effects 2. Zinc, is decreased in patients who have deficiency of kindney(腎虛) and chronic disease. Fe is decreased in patients who have deficiency of blood(血虛). However copper is increased in patients who have chronic disease and hepatic disease.3 Iron concentration is high in herbs used for tonifying and nourishing yin or blood(補陰補血藥) Zinc concentration is high also in herb used for tonifying kidiney and vital essence(補腎補精藥). In addition. copper concentration Is high in herb used for replenishing qi(補氣藥) 4 In herbal drugs, the therapeutic substances in TCM are not only organic but also inorganic. It seems that trace elements would be one of components in herb for its therapeutic effects. This indicates that therapeutic effects of TCM should be extended not only to herb itself, bur also to trace elements contained in herb.

• Asian Pacific Journal of Cancer Prevention
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• 제15권3호
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• pp.1187-1192
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• 2014

Background: To correlate breast cancer subtypes with prognostic factors, microvessel density (MVD), vascular endothelial growth factor (VEGF) expression and clinical features. Materials and Methods: One hundred cases of primary breast carcinoma were classified using biomarkers on tissue microarray as: luminal A [estrogen receptor (ER)+, HER2-, $Ki-67{\leq}14%$], luminal B [ER+, HER2+ or ER+, HER2-, Ki-67>14%], HER2, triple negative basal-like (TNB) [any basal cytokeratins (CKs, 5, 14, 17) and/or endothelial growth factor receptor (EGFR) expression], and TN without such markers [TNN, null], and assessed for p53, vimentin, VEGF and CD31 immunoperoxidase. Results: Of the 100 cases (mean age, 51 years; mean tumor size, 3.2cm; 56% with nodal metastasis; 89 invasive ductal carcinomas, not otherwise specified, 4 invasive lobular carcinomas, 3 metaplastic carcinomas, and 4 other types) there were 39 luminal A, 18 luminal B, 18 HER2, 15 TNB and 10 TNN. The positivities of basal-like markers in the basal-like subtype were 78.3% for CK5, 40% for CK14, 20% for CK17, 46.7% for EGFR. There was no significant difference in age distribution, tumor size, degree of tubular formation, pleomorphism, lymphovascular invasion, nodal metastasis, MVD, VEGF expression and survival among subgroups. TNs demonstrated significantly higher tumor grade, mitotic count, Ki-67 index, p53 and vimentin and decreased overall survival compared with nonTN. Conclusions: The distribution of breast cancer subtypes in this study was similar to other Asian countries with a high prevalence of TN. The high grade character of TN was confirmed and CK5 expression was found to be common in our basal-like subtype. No significant elevation of MVD or VEGF expression was apparent.

• 대한한의학원전학회지
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• 제33권4호
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• pp.1-19
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• 2020

Objectives : This paper aims to understand the meaning and utilitarian values of 'Jongyong(從容)' in medicine by studying its meaning in the 『Huangdineijing』. Methods : Examples of 'Jongyong(從容)' usages in Chinese literature and classical texts were studied first. Next, the similarities and characteristics of its contexts in discourses between Leigong and Huangdi were examined, followed by further examination of the overall meanings of the six chapters, 「Shicongronglunpian(示從容論篇)」, 「Zhuzhijiaolunpian(著至敎論篇)」, 「Shuwuguolunpian(疏五過論篇)」, 「Zhengsishilunpian(徵四失論篇)」, 「Yinyangleilunpian(陰陽類論篇)」, 「Jiejingweilunpian(解精微論篇)」 and the verses that include 'Jongyong(從容).' Results : Generally 'Jongyong(從容)' describes a resilient attitude that responds appropriately and calmly to difficult external situations while maintaining one's character, or refers to one's general behavior. In the 『Huangdineijing』, 'Jongyong(從容)' is only mentioned in discourses between Leigong and Huangdi, which talks about ancient East Asian clinical medicine in general, its transmission and education. Here, the meaning of 'Jongyong(從容)' could be summarized as an expansion of analogical thinking[引比類], medical work that involves the physician's commitment(人事), and detailed measurement of yinyang difference in the body(刑法, 陰陽, 治數). Discussion : In ancient East Asian medicine, the meaning of 'Jongyong(從容)' is closer to measurement of the yinyang difference rather than differentiation of the five element analogy. It is a medical practice that measures the shape, volume, length, area, height, concentration etc. of the human body in numerical figures to allow for the most subtle comparison, which was an important aspect of the physician's work that needed to be demonstrated, educated and transmitted to later generations to enable continuity of the medical profession.

• 대한한방내과학회지
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• 제37권1호
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• pp.1-7
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• 2016

Objectives: This study aimed to investigate the sociodemographic factors of stroke patients.Methods: Patients were hospitalized at Korean medical hospitals with cerebral hemorrhage and infarction and then discharged between September 2013 and August 2014. We investigated the patients’ general character and risk factors, then the patients were classified according to the regions where they reside.Results: The results indicated that having hypertension and diabetes mellitus as an underlying disease was more common in stroke patients from the country. No other statistical significance was noted among the indexes of any other results.Conclusions: Based on these results, hypertension, and diabetes mellitus were more important risk factors in patients from the country than they were for city residents. Further large-scale studies are needed to generalize the findings of this study.

• 사상체질의학회지
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• 제15권3호
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• pp.33-61
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• 2003

This paper was written in order to study the correlation of Taeumin's symptomatic phamacology to Chinese Febrile medicine. Through the symptoms and Clinical cases, treatments of the epidemic febrile disease in ${\ulcorner}Dongyi$ Suse $Bowon\{lrcorner}$ , the symptomatic phamacology for Taeumin was compared with chinese febrile medicine. The following conclusions were reached as a result of comparing the epidemic febrile disease in Taeumin with Chinese febrile medicine. 1. The concept of the epidemic febrile disease in Chinese febrile medicine is wider than that of the epidemic febrile disease in ${\ulcorner}Dongyi$ Suse $Bowon\{lrcorner}$ 2. The cause of the epidemic febrile disease in Chinese febrile medicine is fevershiness almost, but the So-byung(An Natural-Ordinary Disease) of Taeumin in ${\ulcorner}Dongyi$ Suse $Bowon\{lrcorner}$ is the basic method to diagnose the symptom of the epidemic febrile disease. 3. The So-byung of Taeumin in ${\ulcorner}Dongyi$ Suse $Bowon\{lrcorner}$ is divided into feverish symptom and cold symptom according to the so-byung. 4. In ${\ulcorner}Dongyi$ Suse $Bowon\{lrcorner}$, The method of a curative means is based on differing dimensions of the Visera and bowels, but Chinese Febrile Medicine has a equal curative means irrelevant to a patient's character.

• 대한통합의학회지
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• 제1권3호
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• pp.97-109
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• 2013

Purpose : The purpose of this study work for the therapy and how students perceive the occupational therapist was to find out how. Method : The subjects in Busan and Kyungnam located in three two-year colleges and four-year clinical experience of two college students completed work therapeutics were expressed any research to understand the purpose of those who agreed to participate in the survey responded to the 175 people working Therapeutics two, three, four grades were included in the study. Result : 1. Education according to the image of the occupational therapist in grades four-year professional, the value and worth, the patient understand the position was higher in order. 3-year sophomore highly skilled in, the patient understand the position, sincerity was higher in order. 2. Gender occupational therapist who specializes in images for men, the value and worth, high practician was higher in women who were professional, the value and worth, helfer as high. 3. Theory of motivation based on the value of occupational therapists and rewarding images aptitude and interest, high practician, attractive, intellectual was in order. Entrance examination scores as a professional party, value & worth, abuse of authority ceremony was in order. 4. Image by Place of Practice Rehabilitation Hospital occupational therapist who specializes in, high practician, intellectual was in order. Care in the hospital and rewarding value, the professional character, high practician was in order. Hospital and rewarding the value, who specializes in, hepfer was in order. University Hospital who specializes in, the value and worth, Attractive was in order. Conclusion : It had revealed that occupational image perception of occupational therapy student was positive.

• Journal of Korean Neurosurgical Society
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• 제52권5호
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• pp.472-475
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• 2012

Objective : The aim of this study is to establish the value of hand elevation test as a reproducible provocative test for the diagnosis of carpal tunnel syndrome (CTS). Methods : We had a prospective study of 45 hands of 38 patients diagnosed with CTS between April 2005 and February 2009. The diagnosis of CTS was based on the American Academy of Neurology clinical diagnostic criteria. Experimental and control group patients underwent Tinel's test, Phalen's test, carpal compression test and hand elevation test as provocative tests for CTS. Results : We used chi-square analysis to compare Tinel's test and Phalen's test, carpal compression test with hand elevation test. The sensitivity and specificity of the hand elevation test is 86.7% and 88.9% each. Tinel's test had 82.2% sensitivity and 88.9% specificity. Phalen's test had 84.4% sensitivity and 86.7% specificity. Carpal compression test had 84.4% sensitivity 82.2% specificity. Comparisons of sensitivity and specificity between hand elevation test and Tinel's test, Phalen's test, and carpal compression test had no statistically significant differences. To compare the diagnostic accuracies of four tests, the area under the non-parametric receiver operating character curve was applied. Conclusion : The hand elevation test has higher sensitivity and specificity than Tinel's test, Phalen's test, and carpal compression test. Chi-square statistical analysis confirms the hand elevation test is not ineffective campared with Tinel's test, Phalen's test, and carpal compression test.

• 동의신경정신과학회지
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• 제12궈1호
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• pp.11-27
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• 2001

In oriental medicine, from old times, psychological therapy has been regarded as physical therapy that has been inseparable from psychological therapy. The major objects for oriental psychological therapy is human emotions. Human emotions can be put in the seven feelings(七精) that include Joy(善), Anger(怒), Grief(思), Pity(悲), Fear(恐), Surprise(驚). The seven feelings are connected with human physiology. If each of the seven feelings if excessive, human physiology loses its valance. So the seven feelings are major causes of diseases. The specific character of oriental neuropsychiatry is to make use of the seven feelings in clinical treatment. These oriental neuropsychiatry therapies are performed through consultation with the patient. Of these therapies, Oh-Ji-Sang-Seung(五志相勝療法) is based on the theo교 of interrelation in five elements(metal, wood, water, fire, and earth) in oriental medicine. Specially the sequential subjugations of the five emotions are applied. The contents of Oh-Ji-Sang-Seung(五志相勝療法) include five subjugations of five emotions. Anxiety subjugates fear(思勝恐), fear subjugates joy(恐勝喜), joy subjugates pity(喜勝悲), pity subjugates anger(悲勝怒) and anger subjugates anxiety(怒勝思). The psychological therapy of Oh-Ji-Sang-Seung(五志相勝療法) can be applied in all area of neuropsychiatry. These days, many mental diseases such as Panic Disorder, Depression Somatoform disorders, and negative symptoms of Schizophrenia have been improved by Oh-Ji-Sang-Seung(五志相勝療法) therapy. Here, we present the treatment cases applied Oh-Ji-Sang-Seung(五志相勝療法) therapy in oriental medicine quoted from old oriental books and the latest treatment cases. Moreover, we hope that many oriental therapist will treat many different patients with mental disorders by Oh-Ji-Sang-Seung(五志相勝療法) therapy.

• Tuberculosis and Respiratory Diseases
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• 제53권3호
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• pp.349-353
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• 2002

여러 국내외 논문에서 hormone 치료는 우수한 효과를 나타내었으나 치료 종료 후 객혈이 다시 발생하여 추가적인 수술을 받는 경우가 많았으며, GnRH analogue의 장점에도 불구하고 hormone 치료로 완치된 예는 대부분 danazol에 의한 경우가 많았다. 저자들이 경험한 환자는 월경과 동반된 객혈, 월경주기에 따라 변하는 방사선학전 변화와 GnRH analogue 치료에 대한 극적인 증상의 호전 등의 전형적인 소견으로 폐실질 자궁내막증에 의한 catamenial hemoptysis로 진단되었다. 6회의 hormone 치료 기간동안 임상양상의 호전을 보였고, 치료를 중단한 후에도 재발의 증거가 없는 상태로 외래를 다니고 있다.

• 대한구순구개열학회지
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• 제11권1호
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• pp.1-12
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• 2008

In cleft palate patient, characteristic of speech disorder is the resonance disorder result from velopharyngeal incompetence. Clinically VPI caused by congenital factor as congenital palatal incompetence, submucosal cleft palate, and caused by acquired factor as CNS damage, tumor, palatal palsy. The clinicians more concerned about the speech disorders after cleft palate surgery rather than language pathologist. The resonance disorder devided for hypernasality, hyponasality and nasal emission, but as a rule, hypernasality is typical phenomenon of the resonance disorder. Traditionally clinicians and language pathologists evaluated four-stage or five-stage of hypernasality by subjective assessment. Although language pathologist is well-trained, results of the language level should be different. In late 1980s, Kay Elemetrics Corp. developed nasometer that objective nasalance identified with well-trained language pathologist and originate from nasometer Tonar I and II were developed by Fletcher. Therefore objective nasalance test was possible, the nasometer used in hospital, collage and speech clinic both and home and abroad. Standardization of the cleft palate speech assessment must be settled without delay because of different character result in different language and different assessment results by dialect in same language. In our study, we provide the data base for the standardization of cleft palate speech assessment which through report of objective assessment method, speech therapy effects and problems result in interdisciplinary teamwork by nasometer use in treatment of cleft palate patient.