• 대한한방부인과학회지
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• 제32권2호
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• pp.71-86
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• 2019

Objectives: The purpose of this study is to assess the quality of case reports from the Journal of Obstetrics and Gynecology of Korean Medicine. Methods: Case reports were selected from the Obstetrics and Gynecology of Korean Medicine from January 2015 to March 2019, by utilizing Oriental Medicine Advanced Searching Integrated System (OASIS). The quality of the reports were reviewed based on the Consensus-based Clinical Case Reporting Guideline Development (CARE) guideline. Results: Total of 41 case reports were finally selected for the assessment. 69.23% of the case reports included necessary information based on the CARE guideline but the rest of the reports did not. More than 50% of the reports were missing data regarding 'Diagnostic challenges', 'Intervention adherence and tolerability', 'Adverse and unanticipated events', or 'Patient perspective or experience', and 'Informed consent'. Also, the reports did not include 'Key word', 'timeline'. Conclusions: Case reports from the Journal of Obstetrics and Gynecology of Korean Medicine have important role in women. Efforts are needed to improve the quality of the case reports as well as to develop reporting guidelines for the Journal of Obstetrics and Gynecology of Korean Medicine.

• 임상간호연구
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• 제29권1호
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• pp.24-41
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• 2023

Purpose: This study aimed to update the previously published nursing practice guideline for prevention of venous thromboembolism (VTE). Methods: The guideline was updated according to the manuals developed by National Institute for Health and Care Excellence (NICE) and Scottish Intercollegiate Guidelines Network (SIGN), and a Handbook for Clinical Practice Guideline Developer Version 10. Results: The updated nursing practice guideline for prevention of VTE was consisted of 16 domains, 46 subdomains, and 216 recommendations. The recommendations in each domain were: 4 general issues, 8 assessment of risk and bleeding factors, 5 interventions for prevention of VTE, 18 mechanical interventions, 36 pharmacological interventions, 36 VTE prevention starategies for medical patients, 25 for cancer patients, 13 for pregnancy, 8 for surgical patients, 7 for thoractic and cardiac surgery, 16 for orthopedic surgery, 10 for cranial and spinal surgery, 5 for vascular surgery, 13 for other surgery, 3 educations and information, and 2 documentation and report. For these recommendations, the level of evidence was 32.1% for level I, 51.8% for level II, and 16.1% for level III according to the infectious diseases society of America (IDSA) rating system. A total of 112 new recommendations were developed and 49 previous recommendations were deleted. Conclusion: The updated nursing practice guideline for prevention of VTE is expected to serve as an evidence-based practice guideline for prevention of VTE in South Korea. It is recommended that this guideline will disseminate to clinical nursing settings nationwide to improve the effectiveness of prevention of VTE practice.

• 대한골대사학회지
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• 제25권4호
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• pp.195-211
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• 2018

Background: To develop guidelines and recommendations to prevent and treat glucocorticoid (GC)-induced osteoporosis (GIOP) in Korea. Methods: The Korean Society for Bone and Mineral Research and the Korean College of Rheumatology have developed this guideline based on Guidance for the Development of Clinical Practice Guidelines ver. 1.0 established by the National Evidence-Based Healthcare Collaborating Agency. This guideline was developed by adapting previously published guidelines, and a systematic review and quality assessment were performed. Results: This guideline applies to adults aged ${\geq}19years$ who are using or plan to use GCs. It does not include children and adolescents. An initial assessment of fracture risk should be performed within 6 months of initial GC use. Fracture risk should be estimated using the fracture-risk assessment tool (FRAX) after adjustments for GC dose, history of osteoporotic fractures, and bone mineral density (BMD) results. All patients administered with prednisolone or an equivalent medication at a dose ${\geq}2.5mg/day$ for ${\geq}3months$ are recommended to use adequate calcium and vitamin D during treatment. Patients showing a moderate-to-high fracture risk should be treated with additional medication for osteoporosis. All patients continuing GC therapy should undergo annual BMD testing, vertebral X-ray, and fracture risk assessment using FRAX. When treatment failure is suspected, switching to another drug should be considered. Conclusions: This guideline is intended to guide clinicians in the prevention and treatment of GIOP.

• Biomolecules & Therapeutics
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• 제17권1호
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• pp.1-11
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• 2009

Since the Committee for Proprietary Medicinal Products (CPMP) of the European Union issued in 1997 a "points to consider" document for the assessment of the potential for QT interval prolongation by non-cardiovascular agents to predict drug-induced torsades de pointes (TdP), the QT liability has become the critical safety issue in the development of pharmaceuticals. As TdP is usually linked to delayed cardiac repolarization, international guideline (ICH S7B) has advocated the standard repolarization assays such as in vitro IKr (hERG current) and in vivo QT interval, or in vitro APD (as a follow up) as the best biomarkers for predicting the TdP risk. However, the recent increasing evidence suggests that the currently used above biomarkers and/or assays are not fully predictive for TdP, but also does not address potential new druginduced TdP due to the selective disruption of hERG protein trafficking to the cell membrane or VT and/or VF with QT shortening. There is, therefore, an urgent need for other surrogate markers or assays that can predict the proarrhythmic potential of drug candidate. In this review, we provide an ideal pre-clinical strategy to predict the potentials of QT liability and lethal arrhythmia of the drug candidates with recent issues in this field in mind, not at the expense of discarding therapeutically innovative drugs.

• 대한한방소아과학회지
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• 제32권3호
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• pp.131-140
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• 2018

Objectives The purpose of this study is to assess the quality of case reports from the Journal of Pediatrics of Korean Medicine. Methods Case reports were selected from the Journal of Pediatrics of Korean Medicine from January 2015 to April 2018, by utilizing Oriental Medicine Advanced Searching Integrated System (OASIS). The quality of the reports were reviewed based on the Consensus-based Clinical Case Reporting Guideline Development (CARE) guideline. Results Total of 13 case reports were finally selected for the assessment. 73.08% of the case reports included necessary information based on the CARE guideline but the rest of the reports did not. More than 50% of the reports were missing data regarding 'Timeline', 'Diagnostic challenges', 'Intervention adherence and tolerability', 'Adverse and unanticipated events', or 'Patient perspective or experience'. Also, the reports did not include 'Key word', 'Introduction in abstract', 'Case presentation in abstract', or 'The rationale for conclusions' information. Conclusions Case reports from the Journal of Pediatrics of Korean Medicine have important role in pediatrics. Efforts are needed to improve the quality of the case reports as well as to develop reporting guidelines for the Journal of Pediatrics of Korean Medicine.

• 임상간호연구
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• 제22권3호
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• pp.285-293
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• 2016

Purpose: The purpose of this study was aimed to develop evidence-based nursing practice guideline for preventing intermittent urinary catheterization (IUC) related complications using guideline remake process. Methods: Guideline remake process was conducted according to guideline adaptation manual developed by Gu et al (2012) which consisted of three main phases and 9 modules including a total of 24 steps. Results: Newly developed IUC guideline consists of introduction, overview of intermittent catheterization, summary of recommendations, recommendations, references, and appendices. There were 50 recommendations in 5 sections including assessment, equipments, catheterization, complications management, and education/consult. Three recommendations (6%) were graded A, and five (10%) and 41 recommendations(82%) were B and C, respectively. Conclusion: The IUC remade-guideline was developed based on evidence-based nursing and therefore, this guideline is recommended to be disseminated and utilized by nurses nationwide to improve the quality of care for IUC and to decrease the IUC related complications.

• 임상간호연구
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• 제25권1호
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• pp.1-14
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• 2019

Purpose: This study was done to develop a evidence-based guideline for pain assessment and management in Korea by adapting previously developed pain guidelines. Methods: The guideline adaptation process was conducted using 24 steps according to the guideline adaptation manual developed by Hospital Nurses Association in 2012. Results: The newly developed pain management guideline consisted of 9 domains and 234 recommendations. The number of recommendations in each domain was: 13 general instruction items, 51 pain assessments, 14 pain interventions, 66 pharmacological interventions for acute pain, 41 pharmacological interventions for chronic cancer pain, 35 pharmacological interventions for chronic noncancer pain, 21 non-pharmacological interventions, 2 documentations, 10 nursing education items, for pain. Conclusion: The findings suggest that the new pain management guideline can be used to address pain in hospital settings.

• Tuberculosis and Respiratory Diseases
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• 제80권3호
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• pp.221-225
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• 2017

Since 2015, the Health Insurance Review and Assessment Service (HIRA) has performed annual qualitative assessments of asthma management provided by all medical institutions that care for asthma patients in Korea. According to the third report of qualitative assessment of asthma management in 2017, the assessment appears to have contributed to improving the quality of asthma care provided by medical institutions, especially primary clinics. However, there is still a gap between the ideal goals of asthma management and actual health care policies/regulations in real clinical settings, which leads to the state of standstill with respect to the quality of asthma management despite considerable efforts such as the qualitative assessment of asthma management by national agencies such as the HIRA. At this point, a harmonized approach is needed to raise the level of asthma management among several components including medical policies, efforts of academic associations such as education and distribution of the guideline for management, and reliable financial support by the government.

• 임상간호연구
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• 제21권1호
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• pp.31-42
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• 2015

Purpose: This study was done to develop evidence-based nursing practice guidelines to prevent complications related to indwelling urinary catheterization (IUC) in patients in Korea. Methods: A guideline adaptation process was conducted according to the guideline adaptation manual which consists of three main phases, and 9 modules with a total of 24 steps. Results: The newly developed IUC guideline consisted of an introduction, urinary catheterization, summary of recommendations, recommendations, references, and appendices. There were 110 recommendations in 8 sections including assessment, equipment, catheter insertion, catheter maintenance, catheter change, catheter removal, management of complications, and education/consultation. For the grade of recommendations, there were 6.4% for A, 22.7% for B, 67.3% for C. Conclusion: The IUC guideline was developed based on evidence and therefore it is recommended that this guideline be disseminated and utilized by nurses nationwide to improve the quality of care for patients with IUC and decrease complications related to IUC and that it be revised regularly.

• 대한예방한의학회지
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• 제23권2호
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• pp.67-76
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• 2019

Objectives : The publication of systematic reviews (SRs) has increased significantly over the years, and systematic reviews are considered to have the strongest evidence as they are at the top of the hierarchy of evidence pyramid. In this study, a thorough assessment of all SRs published in Journal of Society of Preventive Korean Medicine (JSPKM) was performed to evaluate their reporting quality and methodological quality to better improve the quality of SRs in JSPKM. Methods : JSPKM website was searched to include all SRs published in JSPKM from 1997 to 2018. Two independent researchers assessed the SRs using A MeaSurement Tool to Assess systematic Reviews (AMSTAR, formerly known as Assessment of Multiple Systematic Reviews) tool checklist for methodological quality assessment, and Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline checklist for reporting quality assessment. Results : Out of 618 published articles published in JSPKM from 1997 to 2018, only 3 SRs were identified as SRs. For AMSTAR methodological quality scoring, the average score of 3 SRs was 3.0 out of 11 which is low quality level. For PRISMA reporting quality items, the 3 SRs reported 17.3 items on average out of 27 items. The 3 identified SRs did not provide information on protocol or registration which is included in both AMSTAR assessment tool and PRISMA guideline. Conclusions : Improvements on reporting quality and methodological quality of SRs using relevant tools or guidelines are needed to assure the quality of SRs published in JSPKM so that their conclusions will be more transparent and reliable for decision-making in healthcare and the best clinical practice.