• Archives of Plastic Surgery
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• v.45 no.6
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• pp.557-563
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• 2018

Background Numerous Dupuytren's fasciectomy techniques have been described, each associated with unique surgical challenges, complications and recurrence rates. We describe a common ground surgical approach to Dupuytren's disease; 3-dimensional fasciectomy (3DF). 3DF aims to address the potential contributors to the high recurrence rate of Dupuytren's disease and unite current limited fasciectomy practice that varies considerably between surgeons. Methods We describe the 3DF principles; raising thin skin flaps (addressing dermal involvement), excising diseased palmar fascia with a 3-5 mm clearance margin (treating highly locally recurrent conditions) and excising the vertical septae of Legueu and Juvara (providing deep clearance, hence addressing all potentially involved pathological tissue). The surgical outcomes between traditional limited fasciectomy (LF) and 3DF are compared. Results From the 786 operations included (n=585), postoperative recurrence rates were significantly lower for the 3DF group (2/145, 1.4%) than the LF group (72/641, 11.2%) (P= 0.001), and the time to recurrence was significantly longer ($5.0{\pm}0years$ vs. $4.0{\pm}0.2years$; P<0.0001). With recurrence excluded, there were no differences between the postoperative complication rates for 3DF (5/145, 3.5%) and LF (41/641, 6.4%) (P=0.4). Conclusions Our results suggest that 3DF leads to lower recurrence rates and a longer disease-free period for patients, without increasing complications. 3DF provides a safe, efficacious, common ground surgical approach in the treatment of Dupuytren's flexion deformity.

• Ocean and Polar Research
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• v.31 no.3
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• pp.265-276
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• 2009

Acartia hongi is the most dominant and widespread planktonic copepod in Gyeonggi Bay, Yellow sea. Ingestion rates and selectivity of A. hongi on phytoplankton and planktonic ciliates were determined in the laboratory. Ingestion rates of A. hongi on planktonic ciliates and phytoplankton increased in proportion to prey concentration increase. When A. hongi was fed with various mixture combinations of planktonic ciliates and phytoplankton, their ingestion rate on ciliates tended to increase as the percentage of ciliates in prey biomass increased. Clearance rate of A. hongi on planktonic ciliates was higher than for phytoplankton in all experiments without regard to relative percent of ciliate biomass. This trend suggests that A. hongi was preferentially preying on planktonic ciliates. Under mixed prey availability, it is likely that selective feeding and higher clearance rate of planktonic ciliates by A. hongi is related to the higher nutritional value of ciliates compared to phytoplankton. Therefore, our results suggest that selective ciliate feeding by A. hongi will positively benefit its growth and abundance, and as a result negatively impact the population dynamics of planktonic ciliates in Gyeonggi Bay.

• YAKHAK HOEJI
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• v.45 no.2
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• pp.205-213
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• 2001

The dopaminergic receptors were consisted of two distinct subtypes, $D_1$and $D_2$, each having different function. The present study was attempted to investigate the effects of R(-)-2,10,11-trihydroxy-N-n-propylnoraporphine (TNPA), a dopamine $D_2$receptor agonist, on renal function in dog. TNPA (5.0~15.0 $\mu$g/kg), when given into the vein, produced a dose-dependently antidiuresis along with the decrease in osmolar clearance ( $C_{osm}$) and urinary excretion of sodium and potassium ( $E_{Na}$ , and $E_{K}$). It also increased reabsorption rates of sodium and potassium in renal tubules ( $R_{Na}$ , $R_{K}$) without any changes in glomerular filtration rate (GFR), renal plasma flow (RPF) and free water clearance ( $C_{H2o}$). TNPA (0.5~1.5 $\mu$g/kg/min) infused into a renal artery decreased urine flow both in the experimental and the control kidneys. TNPA (1.5~5.0 $\mu$g/kg) administered via the carotid artery also greatly exhibited antidiuresis even at intravenously ineffective doses. Changes of renal function by TNPA given into both the renal artery and the carotid artery were almost the same aspect to those induced by intravenous TNPA. These results obtained from the present study suggest that TNPA produces antidiuresis by increasing the reabsorption rates of electrolytes in renal tubules, mainly distal tubule, through changing of central function.unction.

• The Korean Journal of Malacology
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• v.31 no.3
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• pp.203-212
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• 2015

This study was performed to describe the influence of temperature on the clearance rate and ingestion rate of the blue mussel, Mytilus galloprovincialis with three food organisms and habitat location (shell size) of mussel. Food organisms used in this experiments were Isochrysis galbana, Chaetoceros didymus and Prorocentrum dentatum. The size of mussels inhabiting higher midlittoral zone was smaller than those of lower midlittoral zone. Regardless of the kind of food organisms, filtration rates and ingestion rates of higher midlittoral mussels were higher than those of lower midlittoral mussels in experiment temperature conditions. The variation of filtration rate and ingestion rate showed same tendency with temperature. Filtration rates and ingestion rates increased with temperature, and recorded maximum values at $20-25^{\circ}C$ of temperature, and thereafter decreased gradually. Theoretical optimum temperatures showing maximum filtration rates and ingestion rates estimated from polynomial regression curves were also in the range of $20-25^{\circ}C$. Blue mussels showed different variation of filtration rate and ingestion rate with the kind of food organisms. Filtration rates and ingestion rate based on cell number were similar regardless of habitat location(tidal elevation) and food organisms. Ingestion rates based on carbon content showed very high values in case of P. dentatum beside I. galbana and C. didymus as food organism.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.30 no.4
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• pp.195-203
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• 2018

Mohair is widely used as an airtight material for filling the gap between a window frame and sash. The purpose of this study is to investigate infiltration rate and opening force of sliding windows according to the mohair installation conditions. Infiltration experimental apparatus was set up, and the experimental results were applied to windows to find a correlation between infiltration rates and opening forces. When 4 rows of mohair were installed, the infiltration rate increase became 27.1% per clearance length increase of 1 mm, and the infiltration rate decrease became 5.7% per shortened length increase of 0.1 mm. For 4 rows of mohair, the opening force decreased by 28.2% as the clearance increased by 1 mm, and it increased by 9.3% as the shortened length increased by 0.1 mm.

• 한국해양학회지
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• v.30 no.5
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• pp.458-466
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• 1995

To clarify the role of protozooplankton in the microbial food web of Inchon coastal ecosystem, the grazing capacities and growth rates of heterotrophic flagellated (HFL) and ciliates were investigated. We measured the growth rates of bacteria, HFL, autotrophic flagellated (AFL) and ciliates using reverse flow (RF) filter set and obtained the clearance rates and ingestion rates of HFL and dilates by fluorescent labelled bacteria (FLB) method and isolation culture method from natural seawater of Inchon coastal area. The standing crops of bacteria, HFL, AFL and ciliates in this study area were 0.7∼1.5${\times}$10/SUP 6/ cells$.$ml/SUP -1/ 1,680∼2,180 cells$.$ml/SUP -1/, 1,090∼2,180 cells$.$ml, and 3,600∼5,700 cells$.$l/SUP -1/, respectively. The mean growth rates of bacteria, HFL, AFL and ciliates were 0.039 h/SUP -1/, 0.032∼0.033h/SUP -1/, 0.015∼ 0.025h/SUP -1/and 0.021h/SUP -1/, respectively. The growth rates of protozooplankton of Inchon coastal waters were relatively low. Mean grazing rate of HFL, AFL and ciliates were0.039 h/SUP -1/, 0.032∼0.033h/SUP -1/,0.015∼ 0.025h/SUP -1/and 0.021h/SUP -1/, respectively. The growth rates of protozooplankton of Inchon coastal waters were relatively low. Mean grazing rate of HFL on bacteria was 0.055h/SUP -1/. Mean grazing rates of ciliates on HFL was relatively high of 0.057 h/SUP -1/, while the grazing rate of ciliates on AFL was low of 0.019h/SUP -1/. The clearance rates and ingestion rates of HFL on bacteria were 3.6∼61.8nl$.$HFL$.$h/SUP -1/ and 6∼52 BAC. HFL$.$h/SUP -1/ respectively. FLB grazing experiment showed low values, while natural bacteria experiment showed high value meaning high grazing pressure on total bacteria. The clearance rates and ingestion rates of Tintinnopsis sp., dominant ciliates in Inchon coastal waters, were 3.2∼4.6 ul$.$CIL/SUP -1/$.$h/SUP -1/ and 5∼6 cells$.$CIL/SUP -1/$.$h/SUP -1/ respectively, showing higher values in the high tide than low tide. The ingestion rates of ciliates implies that ciliate took up 17∼20% of total nanoflagellates of Inchon coastal waters.

• YAKHAK HOEJI
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• v.29 no.3
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• pp.130-143
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• 1985

Bumetanide, when given intravenously in dogs, induced a potent diuresis with an increased amounts of sodium and potassium excreted in urine due to inhibition of reabsorbing them in renal tubule. Furthermore, clearances of osmolar substance and para-aminohippuric acid were increased, but clearace of free water diminished without any change of creatinine clearance. Bumetanide, administered directly into a renal artery, elicited diuresis only in the infused(experimental) kidney by the same mode of action as in the intravenous cases in renal function of the dog. Renal effects of intravenous bumetanide after pretreatment with the small dose of indomethacin (5.0mg/kg) revealed reduction only in clearance of paraaminohippuric acid. However the much dose of indomethacin (5.0mg/kg+5.0mg/kg/hr) or arachidonic acid showed a significant inhibition in the change rates of all renal function by bumetanide. Morover, pretreatment of probenecid also made a marked reduction in renal effects induced by bumetanide. From the above results, it is thought that bumetanide causes diuretic action due to dual mechanism inhibiting reabsorption of electrolytes in loop of Henle and increasing blood flow in kindney, that are provoked through the mediation of prostaglandins.

• Korean Journal of Clinical Pharmacy
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• v.3 no.2
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• pp.163-168
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• 1993

The influence of cimetidine pretreatment(100mg/kg, single i.p.) on the hepatic blood flow was investigated using pharmacokinetic parameters of indocyanine green(ICG) in the rat on the basis of hepacc perfusion-limited model. ICG(1mg/kg) was respectively administered via femoral and portal vein to the control and to the cimetidine-pretreated rats. The rate constant K12, K20 and the systemic clearance(CLt) of ICG were significantly(p<0.05) decreased ill the cimetidine-pretrea-to(B rats, but no significant diffirences were observed in hematocrit and liver weight. The biliary excretion rates of ICG were also decreased regardless of the route of administration in the cimetidine-pretreated rats. And also the hepatic blood flow in rats was decreased about $16\%$ by cimetidine. It may be concluded that the decreased hepatic blood flow with cimetidine mainly contributed to the decreased hepatic uptake and the decreased systemic clearance of ICG.

• Journal of Biosystems Engineering
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• v.20 no.4
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• pp.360-367
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• 1995

The effect of air vent holes, stacking methods of boxes and clearance between boxes on static pressure drop, were measured to design of pressure cooling system. Static pressure drops in air vent hole of carton box were measured for different hole opening ratio from 1% to 5%. Static pressure drop was expressed as a function of superficial velocity as second-degree polynomial. At given static pressure in plenum chamber, static pressure drop in boxes was shown as second-degree polynomial of the number of carton box in series stacking method, as first-degree polynomial in height and parallel stacking method. In pressure cooling of 24 boxes of Tsugaru apple, air flow rates through clearance between the boxes were shown 1.27 and 1.65 times than those of through the inside of boxes at the plenum pressure of 10mmAq and 20mmAq, respectively.

• Transactions of Materials Processing
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• v.24 no.5
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• pp.323-331
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• 2015

Impact extrusion is an economical and productive process that can replace the multistage deep drawing process for producing deep rectangular cases. In the current work, a three-dimensional finite element analysis of the impact extrusion process of a commercial purity aluminum alloy (AA1070) was performed to predict loads, material flow, and deformed shapes using the Hansel-Spittel rheology law, which describes the flow stress at various temperatures and strain rates. The role of various process parameters such as friction, clearance between punch and die, aspect ratio and thickness of billet on the process and the shapes was analyzed.