• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2000년도 춘계 학술대회 및 국제 감성공학 심포지움 논문집 Proceeding of the 2000 Spring Conference of KOSES and International Sensibility Ergonomics Symposium
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• pp.62-66
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• 2000

This study investigated the effects of certain specific wavelengths of lighting on the autonomic nervous system (ANS) using the heart rate variability (HRV) as an index. Six subjects with normal color vision participated n this study between 15:00 and 17:00 hr to neutralize any visual differences arising from circadian rhythm. The environmental conditions of the laboratory were maintained in complete darkness and the temperature was equilibrated at 24$\Box$ with a relative humidity of 60%. Subjects were only subjected to light stimulation when the pupil of dyes attained a minimum size of 2 mm by projecting illumination equalized with the same spectral radiance of 500-700 nm with 50-nm internal radiance. HRV was calculated from electrocardiogram (ECG) with systematic respiratory control at 0.35 Hz. The results suggest that illumination with certain wavelengths may induce ANS activation.

• 대한상한금궤의학회지
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• 제11권1호
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• pp.153-167
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• 2019

Objective : To explore the meaning of Eumyangyeokchahunobok-byung (陰陽易差後勞復病) through two cases and finding the relationship with the DSM-5 sleep-wake disorder. Methods : Following a disease pattern identification diagnostic system based on Shanghanlun provisions (DPIDS), we analyzed cases with chronic fatigue and diplopia caused after sleep disorders. The patients were treated with the Soshiho-tang and Yijoong-tang. Results : The two herbal medicines showed remarkable improvement in the patients. The sleep disorders and the secondary pathologies were rapidly relieved within a month. Conclusions : The patterns of sleep disorders of the two patients were found to be very similar to the circadian rhythm sleep-wake disorders, as described in DSM-5. Although the etymology of the Chinese characters has not been clearly known yet, it was possible to present the original hypotheses on 更and 了due to clinical inference.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1992년도 춘계학술대회
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• pp.181-183
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• 1992

90일간에 걸쳐 수집된 후천성 맹인의 체온데이타를 분석하였다. 이 데이타는 1일 주기 리듬을 갖고 있음을 잘 보여주었으며, 데이타 분석 방법으로는 시계열분석을 이용, 잡음을 제거하고 푸리에분석방법에 의하여 추정데이타를 만든후, 원 데이타와의 오차 자승항이 최소가 되는 주기를 찾는 방법을 사용하였다. 전체 데이타를 1일, 3일, 5일씩의 길이로 잘라서 분석을 하였으며 90여일에 걸친 분석 결과들을 모아 추정파형의 진폭과 서카디안 페이즈를 그래프로 도시하였다. 고찰결과, 1. 이 맹인의 체온데이타는 24, 25시간의 일정한 주기를 갖고있다. 2. 이 데이타는 24시간의 주기와 24, 25시간의 주기로 분리할 수 있다. 3. 따라서 1일 주기리듬의 체온데이타는 근소한 차이의 두 가지 성분이 존재함을 알 수 있다.라는 결론을 내릴 수 있었다.

• 수면정신생리
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• 제19권1호
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• pp.5-10
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• 2012

The release of hormones and the metabolism of human body are controlled by the circadian rhythm related to sleep-wake cycle. Growth hormone, prolactin, thyroid stimulating hormone, cortisol, glucose, and insulin-secretion rates fluctuate according to the sleep-wake cycle. In addition, sleep is related to the appetite regulation and carbohydrate and other energy metabolism. Hypocretin (orexin), an excitatory neuropeptide, regulates waking and diet intake, and the poor sleep increases diet intake. The short sleep duration increases one's body mass index and impairs the function of the endocrine and metabolism, causing increases in the risk of glucose intolerance and diabetes. The poor sleep quality and sleep disorders have similar impact on the metabolic function. In short, the sleep loss and the poor quality of sleep have a detrimental effect on the endocrine and energy metabolism. The improvement of sleep quality by the future research and appropriate clinical treatment would contribute to the decrease of the metabolic diseases such as diabetes.

• 수면정신생리
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• 제10권1호
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• pp.26-31
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• 2003

Restless leg syndrome (RLS) and periodic limb movement of sleep (PLMS), often concurrent, come under diagnosed disorders of sleep and treatable condition. RLS symptoms are evoked in the limbs at rest and increase in the evening and during the night. PLMS is characterized by periodic episodes of repetitive limb movements caused by muscle contractions during sleep. RLS is often associated with a sleep complaint and PLMS. Both RLS and PLMS represent one of the most commonly encountered sleep disorders in a primary care setting. The circadian rhythm and the presence of PLMS cause sleep disturbances in RLS. The emphasis on pathophysiology includes consideration of central nervous system localization, neurotransmitter, and the role of iron metabolism. Dopaminergic agents are considered the treatment of choice for RLS and PLMS. With proper diagnosis and effective treatment patients' ability to fall asleep and maintain sleep improves, and their sense of well being increases.

• 한국지역사회생활과학회지
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• 제18권4호
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• pp.681-686
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• 2007

This study was conducted to investigate the effects of the thermally different states of human feet on temperature regulation in winter season. Five healthy female students of age 20 volunteered as subjects to participate in the study. Physiological responses such as rectal temperature and skin temperatures as well as subjective responses of thermal comfort and thermal sensation were observed. Preferred clothing and preferred temperature were also evaluated in terms of behavioral temperature regulation. The results obtained through the experiment were statistically analyzed using paired t test. Rectal temperature was decreased greater (p<.01) and mean skin temperature was maintained higher (p<.01) in feet wanning than in feet cooling. Results of preferred clothing were coincident with those of general thermal sensation. There was a higher tendency to prefer temperature in feet wanning than feet cooling in the morning. It was concluded that keeping feet skin temperature lower in the early morning and higher in the late evening would be effective in terms of regulating circadian rhythm of core temperature.

• 수면정신생리
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• 제20권2호
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• pp.59-62
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• 2013

Alcohol has been used as sedatives historically. The effect of alcohol on sleep is different according to its dose, timing of ingestion, and drinking frequency. Sleep problems may play a role in the development and course of alcohol-related disorders. Insomnia in alcohol-dependent patients is common and early treatment of insomnia may reduce the rate of relapse. Sleep apnea, restless legs syndrome, periodic limbs movement disorder, and altered circadian rhythm may be more frequent in this patients. Management of sleep and alcohol problems is important in treating alcohol-related disorder and sleep disorders, respectively.

• 산업경영시스템학회지
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• 제30권2호
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• pp.58-66
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• 2007

This study is evaluation of shift-workers' sleep and social life related to hospital workers' performance and health. We researched shiftworkers' sleep, sleeping quality and social relations using a questionnaire method to shiftworkplace scattered Daejeon and Chungnam province. The results of shiftworkers' sleep are differ from habitual sleep. Social participations of shiftworkerse are interfered partially because of shiftwork. In preference, shiftworker preferred health to others because of physical load of shiftworks. Through result of this study about sleep and social life style, we hope to derive reduction methods of shift work fatigue and education for improvement of employers, for example an physiological and psychological accordance method, an health problem solving method and an social accordance method, etc.

• Journal of Plant Biology
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• 제25권1호
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• pp.21-36
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• 1982

The activity of photosystem II in isolated chloroplast form the leaves of Sedum sarmentosum was measured. The photoreduction rate of DCPIP by photosystem II showed the circadian rhythm with a peak at near midday sample for a continuing fine day and at near afternoon between nidday and sunset sample for a continuing cloudy day in summer. The optimum light intensity of photoreduction by photosystem II in the chloroplast preparation was about 5~9$\times$$10^4$ lux. The saturated light intensity was over 9$\times$$10^1$lux. Photosystem II activity was inhibited by even the lowest concentration of lead. When Pi and ATP of the same concentration as Pb were added to the reaction mixture containing Tris buffer lacking of Pi prior to Pb incubation, photosystem II activity was protected from Pb-inhibiting effect by the pretreament of Pi and ATP. It was assumed that Pb inhibiiton was probably due to one, P-depriving by the precipitates of $Pb_3$ $($Pb_4$)_2$ in the reaction mixture and the other, partially Pb-combing with Pi groups of the active site of photosystem II.

• 통합자연과학논문집
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• 제5권2호
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• pp.65-71
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• 2012

Neuropeptide Y (NPY), a 36-amino acid polypeptide, is a member of the pancreatic polypeptide family, which consists of NPY, peptide YY (PYY) and pancreatic polypeptide (PP). The neuropeptide Y (NPY) receptors called Y receptors belongs to G-protein coupled that are involved in a variety of physiological functions such as appetite regulation, circadian rhythm and anxiety. Five receptor subtypes have been cloned in mammals (Y1, Y2, Y4, Y5, and Y6) of which four are functional. In this short review, information about the functional NYP receptors was analyzed. Sequence analyses were done between these receptors to identify the relationships between them. Phylogram was generated between these receptors to identify the close homologue between these receptors. Our sequence analyses found that Y1 and Y4 receptors are close than the other receptors. Further structure based analysis could be useful to identify subtype selective antagonists and dual antagonists targeting Y1 and Y4 receptors.