• 제목/요약/키워드: chronic health conditions

검색결과 317건 처리시간 0.031초

전문의약품 소비자광고가 생활습관 변화에 미치는 영향에 대한 연구 (The Impact of Direct-to-Consumer Advertising of Prescription Medications on Healthy Lifestyle)

  • 양혜경
    • 대한가정학회지
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    • 제50권4호
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    • pp.103-113
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    • 2012
  • 전문의약품 소비자광고가 미국에서 급속도로 증가함에 따라 광고가 소비자의 생활습관 변화에 미치는 영향에 대한 관심이 커지고 있다. 전문의약품 소비자광고에 대한 대부분의 선행 연구들이 광고가 소비자 수요에 미치는 영향에 초점을 맞추고 있는데 반해 소비자 행동 특히 건강관련 생활습관 변화에 미치는 영향에 관한 연구는 드물다. 본 연구는 2000년에서 2004년 사이의 미국 소비자 조사와 대중적인 소비자 잡지들에 실린 전문의약품 소비자광고들 중 고지혈증, 고혈압, 당뇨, 비만 치료제 광고를 데이터베이스화한 자료를 이용하여 개별 소비자 수준에서의 광고 노출을 산출하고, 규칙적인 운동, 운동 빈도, 식이 조절 행동에 미치는 영향을 선형확률모형을 이용하여 분석하였다. 본 연구 결과 고지혈증, 고혈압, 당뇨, 비만 등의 만성질환을 보유한 소비자들이 이들 치료제 광고에 노출되어 규칙적인 운동을 할 확률은 감소하는 것으로 나타났으나, 식이조절을 할 확률은 증가하는 것으로 나타났다. 개별 질환 치료제 광고 수준에서 광고 노출의 영향을 살펴본 결과, 고지혈증 보유자들의 경우 고지혈증 치료제 광고 노출이 증가할수록 주당 운동 빈도가 증가할 확률이 높아지는 것으로 나타났으나 고혈압, 비만 환자인 경우 이들 각각의 치료제 광고의 노출이 증가할수록 주당 운동 빈도와 식이 조절을 할 확률이 감소하는 것으로 나타났다. 또한 교육 수준이 낮은 소비자의 경우 광고 노출이 이들이 규칙적으로 운동을 하는데 정의 영향을 미치는 것으로 나타났다. 본 연구의 결과를 통하여 전문 의약품 소비자광고가 소비자와 관련 질환에 따라 다른 영향을 미친다는 것을 알 수 있다. 따라서 전문의약품 소비자광고가 소비자의 건강한 생활습관 향상에 도움이 되도록 하기 위해서는 꾸준한 모니터링이 중요하며, 전문의약품 소비자광고에 건강한 생활습관을 유도할 수 있는 메시지를 포함하도록 규제하는 것이 필요하다.

Determination of Appropriate Sampling Time for Job Stress Assessment: the Salivary Chromogranin A and Cortisol in Adult Females

  • Hong, Ran-Hi;Yang, Yun-Jung;Kim, Sang-Yon;Lee, Won-Young;Hong, Yeon-Pyo
    • Journal of Preventive Medicine and Public Health
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    • 제42권4호
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    • pp.231-236
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    • 2009
  • Objectives : This study was conducted to determine the appropriate sampling time of the salivary stress markers, chromogranin A (CgA) and cortisol as objective indices of job stress assessment in adult females. Methods : The subjects were 20${\sim}$39-year-old women (13 office workers, 11 sales-service workers, and 11 college students) who were eligible for the study and free of acute and chronic medical conditions. Salivary CgA and cortisol levels were determined by enzyme-linked immunosorbent assay (ELISA). Saliva samples were collected (2 $m{\ell}$ each) at 7:00, 8:00, 10:30, 12:00, 17:30, and 22:30 on a typical day. Salivary CgA and cortisol levels, according to sampling time, were compared among the three groups using general linear model. The full version of the Korean Occupational Stress Scale (KOSS), which includes socioeconomic characteristics, health behavior, workrelated characteristics, and BMI, was used to access the subjects' job stress. Multiple regression analysis of the job stressors identified by the KOSS was performed on salivary CgA and cortisol levels. Results : The salivary CgA level peaked at 7:00 (time of awakening), then decreased and were maintained at a low level throughout the day, and increased slightly at 17:30. The salivary cortisol level increased steeply within the 1st hour after awakening, followed by a gradual decrease by 12:00, and was then maintained at a low level throughout the day. The salivary cortisol levels of subjects who worked ${\leq}$5 days per week and graduated from the university were significantly lower at 8:00 (p=0.006). The salivary cortisol levels of non-smokers were significantly lower at 7:00 p=0.040) and 8:00 (p=0.003) compared to smokers. There were no significant differences in salivary CgA and cortisol levels at 10:30 and 12:00 in general characteristics. The regression coefficients on salivary CgA level were significant with interpersonal conflict at 17:30 and job insecurity at 22:30. Regression coefficients on salivary cortisol level were significant with organizational system and total job stressors at 17:30. Conclusions : We suggest that the appropriate sampling times for the salivary stress markers, CgA and cortisol, are at 7:00 (time of awakening), 8:00 (1 hour after awakening), 17:30 (early evening), and 22:30 (before sleep).

일개 종합병원을 이용한 농.어촌지역 퇴원환자의 질병분포에 관한 연구 (The Analysis of Disease Distribution of patients discharged from a general hospital in a farming and fishing village region)

  • 유은영;김율
    • 한국산학기술학회논문지
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    • 제11권12호
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    • pp.4863-4872
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    • 2010
  • 본 연구는 농 어촌지역 환자들을 대상으로 질병양상을 살펴보고 의료이용 실태를 분석하여 농 어촌지역 의료 관련 기관의 보건의료서비스 계획수립에 필요한 자료를 제공 하고자 시행되었다. 노령화가 진행된 농 어촌지역 G도 G군에 소재한 종합병원을 대상으로 2009년 7월부터 12월까지 6개월 동안 퇴원환자 2,365건 전수의 의무기록 자료를 토대로 분석하였다. 분석결과, 조사대상 환자의 성별은 남자 55.3%, 여자 44.7%, 연령별은 70세 이상 후기 고령자가 42%로 나타냈다. 입원유형별로는 외래경유 입원환자가 65.5%이며, 진료과목으로는 내과 49.7%, 정형외과 16.7%, 신경외과 13.8% 순이었다. 주 진단명(3단 분류)별 10대 다 빈도에서 S00-T98 18.4%, J00-J99 15.5%, I00-I99 11.5% 순이었다. 평균재원일수는 14.8일이었으며, 주 진단명을 포함한 상병개수는 평균 5.6개이었다. 주 진단명(3단 분류) 다빈도 10대에서 성별, 보험유형별, 입원경로, 연령별 분포 등이 통계적으로 유의한 차이가 있었다. 월별 주 진단명(3단 분류) 다 빈도 10대 분류 분포는 통계적 유의한 차이가 있었다. 주 진단명(3단 분류) 다 빈도 10대분류에 따른 평균재원일수와 상병개수는 통계적으로 유의한 차이가 있었다. 결론적으로, 농 어촌지역의 질병분포는 작업환경과 연중 신체적 무리가 가는 노동행위에 따른 외상성 질환 및 호흡기 질환과 노령화에 따른 각종 만성질환 등 이었다.

인공관절 전치환 성형 수술 전후의 일상활동 장애정도 및 삶의 만족도 비교연구 - 관절 질환 환자를 중심으로 - (A Comparative Study of the Handicaps in and Satisfaction with the Ordinary Life before and after the Plastic Operation for Artificial Joint Replacement-Centering around Those Who suffer from Joint Diseases)

  • 강신화
    • 근관절건강학회지
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    • 제3권1호
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    • pp.37-49
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    • 1996
  • The joint diseases threaten modern people's healthy life. They bring about a long pain, an anasarca, loss of joint function or even deformation and rigidity of joint, limiting people's ordinary activities much. The chronic joint patients may be subject to some hypochondria caused by anxiety for their life, social isolation, financial problem and physical disability. Therefore, this population should continue to be duely taken care of by medical personnels. In particular, nurses should adequately help these people to recover and improve their health through suitable adaptations. With such basic conceptions in mind, this study was aimed at reviewing these patients' conditions in their ordinary life before and after a plastic operation for artificial joint replacement as well as their satisfaction with their life. For this purpose, those patients who underwent some plastic operations for artificial joint replacement at university hospitals in Seoul from January 2, 1993 to June 30, 1995 were selected as the population of this study. Among them, 87 people were randomly sampled to answer a questionnaire designed specially. For the surveying tools, Jette's (1980) scale was applied to address the sample people's inconveniences experienced and supports received in their ordinary life, while the scale of Wood, Wylie & Sheafer was used to measure their satisfaction with their life. The collected data were analyzed for percentiles, means, SD, t-test and Pearson's correlations. The results of survey can be summarized as follows ; As a result of t-test the frequencies of other people's support before and after the plastic operation, it was disclosed that those who underwent the operation were supported less frequently. In addition, as a result of t-testing their satisfaction with life before and after the operation, it was found that the operation increased their satisfaction with life significantly. Meanwhile, as a result of t-test inconveniences, frequencies of supports and life satisfaction before and after the plastic operation for artificial knee replacement, it was disclosed that only the inconveniences were significantly reduced after the operation. In contrast, the t-test the variables before and after the plastic operation for artificial hip replacement, it was found that only the frequencies of other people's supports were significant reduced after the operation. Furthermore, the differences 6 months, one year and two years after the plastic operation for artificial joint replacement were t-tested on the variables. As a result, it was disclosed that people's inconvenience, frequencies of supports and life satisfaction were not improved 6 months after the operation but their frequencies of supports decreased significantly one year after, while their inconveniences and life satisfaction were significantly improved two years after. As a result of analyzing the variables with Pearson's correlations, inconveniences and frequency of supports were negatively correlated significantly with the life satisfaction. In conclusion, the plastic operation for artificial joint replacement significantly improved people's living inconveniences, reduced their frequency of other people's support and enhanced their satisfaction with life. To break don the plastic operation for artificial knee replacement improved patients' inconveniences, while the plastic operation for artificial hip replacement not only improved patients' inconveniences but reduced the frequencies of other people's support also. Finally, the finding that the plastic operation for artificial joint replacement brought about the improvement two years after suggests that this period is needed for the patients to adapt themselves to the post-operation conditions.

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농촌(農村) 주민(住民)들의 의료필요도(醫療必要度)에 관(關)한 연구(硏究) (A Study Concerning Health Needs in Rural Korea)

  • 이성관;김두희;정종학;정극수;박상빈;최정헌;홍순호;라진훈
    • Journal of Preventive Medicine and Public Health
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    • 제7권1호
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    • pp.29-94
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    • 1974
  • Today most developed countries provide modern medical care for most of the population. The rural area is the more neglected area in the medical and health field. In public health, the philosophy is that medical care for in maintenance of health is a basic right of man; it should not be discriminated against racial, environmental or financial situations. The deficiency of the medical care system, cultural bias, economic development, and ignorance of the residents about health care brought about the shortage of medical personnel and facilities on the rural areas. Moreover, medical students and physicians have been taught less about rural health care than about urban health care. Medical care, therefore, is insufficient in terms of health care personnel/and facilities in rural areas. Under such a situation, there is growing concern about the health problems among the rural population. The findings presented in this report are useful measures of the major health problems and even more important, as a guide to planning for improved medical care systems. It is hoped that findings from this study will be useful to those responsible for improving the delivery of health service for the rural population. Objectives: -to determine the health status of the residents in the rural areas. -to assess the rural population's needs in terms of health and medical care. -to make recommendations concerning improvement in the delivery of health and medical care for the rural population. Procedures: For the sampling design, the ideal would be to sample according to the proportion of the composition age-groups. As the health problems would be different by group, the sample was divided into 10 different age-groups. If the sample were allocated by proportion of composition of each age group, some age groups would be too small to estimate the health problem. The sample size of each age-group population was 100 people/age-groups. Personal interviews were conducted by specially trained medical students. The interviews dealt at length with current health status, medical care problems, utilization of medical services, medical cost paid for medical care and attitudes toward health. In addition, more information was gained from the public health field, including environmental sanitation, maternal and child health, family planning, tuberculosis control, and dental health. The sample Sample size was one fourth of total population: 1,438 The aged 10-14 years showed the largest number of 254 and the aged under one year was the smallest number of 81. Participation in examination Examination sessions usually were held in the morning every Tuesday, Wenesday, and Thursday for 3 hours at each session at the Namchun Health station. In general, the rate of participation in medical examination was low especially in ages between 10-19 years old. The highest rate of participation among are groups was the under one year age-group by 100 percent. The lowest use rate as low as 3% of those in the age-groups 10-19 years who are attending junior and senior high school in Taegu city so the time was not convenient for them to recieve examinations. Among the over 20 years old group, the rate of participation of female was higher than that of males. The results are as follows: A. Publie health problems Population: The number of pre-school age group who required child health was 724, among them infants numbered 96. Number of eligible women aged 15-44 years was 1,279, and women with husband who need maternal health numbered 700. The age-group of 65 years or older was 201 needed more health care and 65 of them had disabilities. (Table 2). Environmental sanitation: Seventy-nine percent of the residents relied upon well water as a primary source of dringking water. Ninety-three percent of the drinking water supply was rated as unfited quality for drinking. More than 90% of latrines were unhygienic, in structure design and sanitation (Table 15). Maternal and child health: Maternal health Average number of pregnancies of eligible women was 4 times. There was almost no pre- and post-natal care. Pregnancy wastage Still births was 33 per 1,000 live births. Spontaneous abortion was 156 per 1,000 live births. Induced abortion was 137 per 1,000 live births. Delivery condition More than 90 percent of deliveries were conducted at home. Attendants at last delivery were laymen by 76% and delivery without attendants was 14%. The rate of non-sterilized scissors as an instrument used to cut the umbilical cord was as high as 54% and of sickles was 14%. The rate of difficult delivery counted for 3%. Maternal death rate estimates about 35 per 10,000 live births. Child health Consultation rate for child health was almost non existant. In general, vaccination rate of children was low; vaccination rates for children aged 0-5 years with BCG and small pox were 34 and 28 percent respectively. The rate of vaccination with DPT and Polio were 23 and 25% respectively but the rate of the complete three injections were as low as 5 and 3% respectively. The number of dead children was 280 per 1,000 living children. Infants death rate was 45 per 1,000 live births (Table 16), Family planning: Approval rate of married women for family planning was as high as 86%. The rate of experiences of contraception in the past was 51%. The current rate of contraception was 37%. Willingness to use contraception in the future was as high as 86% (Table 17). Tuberculosis control: Number of registration patients at the health center currently was 25. The number indicates one eighth of estimate number of tuberculosis in the area. Number of discharged cases in the past accounted for 79 which showed 50% of active cases when discharged time. Rate of complete treatment among reasons of discharge in the past as low as 28%. There needs to be a follow up observation of the discharged cases (Table 18). Dental problems: More than 50% of the total population have at least one or more dental problems. (Table 19) B. Medical care problems Incidence rate: 1. In one month Incidence rate of medical care problems during one month was 19.6 percent. Among these health problems which required rest at home were 11.8 percent. The estimated number of patients in the total population is 1,206. The health problems reported most frequently in interviews during one month are: GI trouble, respiratory disease, neuralgia, skin disease, and communicable disease-in that order, The rate of health problems by age groups was highest in the 1-4 age group and in the 60 years or over age group, the lowest rate was the 10-14 year age group. In general, 0-29 year age group except the 1-4 year age group was low incidence rate. After 30 years old the rate of health problems increases gradually with aging. Eighty-three percent of health problems that occured during one month were solved by primary medical care procedures. Seventeen percent of health problems needed secondary care. Days rested at home because of illness during one month were 0.7 days per interviewee and 8days per patient and it accounts for 2,161 days for the total productive population in the area. (Table 20) 2. In a year The incidence rate of medical care problems during a year was 74.8%, among them health problems which required rest at home was 37 percent. Estimated number of patients in the total population during a year was 4,600. The health problems that occured most frequently among the interviewees during a year were: Cold (30%), GI trouble (18), respiratory disease (11), anemia (10), diarrhea (10), neuralgia (10), parasite disease (9), ENT (7), skin (7), headache (7), trauma (4), communicable disease (3), and circulatory disease (3) -in that order. The rate of health problems by age groups was highest in the infants group, thereafter the rate decreased gradually until the age 15-19 year age group which showed the lowest, and then the rate increased gradually with aging. Eighty-seven percent of health problems during a year were solved by primary medical care. Thirteen percent of them needed secondary medical care procedures. Days rested at home because of illness during a year were 16 days per interviewee and 44 days per patient and it accounted for 57,335 days lost among productive age group in the area (Table 21). Among those given medical examination, the conditions observed most frequently were respiratory disease, GI trouble, parasite disease, neuralgia, skin disease, trauma, tuberculosis, anemia, chronic obstructive lung disease, eye disorders-in that order (Table 22). The main health problems required secondary medical care are as fellows: (previous page). Utilization of medical care (treatment) The rate of treatment by various medical facilities for all health problems during one month was 73 percent. The rate of receiving of medical care of those who have health problems which required rest at home was 52% while the rate of those who have health problems which did not required rest was 61 percent (Table 23). The rate of receiving of medical care for all health problems during a year was 67 percent. The rate of receiving of medical care of those who have health problems which required rest at home was 82 percent while the rate of those who have health problems which did not required rest was as low as 53 percent (Table 24). Types of medical facilitied used were as follows: Hospital and clinics: 32-35% Herb clinics: 9-10% Drugstore: 53-58% Hospitalization Rate of hospitalization was 1.7% and the estimate number of hospitalizations among the total population during a year will be 107 persons (Table 25). Medical cost: Average medical cost per person during one month and a year were 171 and 2,800 won respectively. Average medical cost per patient during one month and a year were 1,109 and 3,740 won respectively. Average cost per household during a year was 15,800 won (Table 26, 27). Solution measures for health and medical care problems in rural area: A. Health problems which could be solved by paramedical workers such as nurses, midwives and aid nurses etc. are as follows: 1. Improvement of environmental sanitation 2. MCH except medical care problems 3. Family planning except surgical intervention 4. Tuberculosis control except diagnosis and prescription 5. Dental care except operational intervention 6. Health education for residents for improvement of utilization of medical facilities and early diagnosis etc. B. Medical care problems 1. Eighty-five percent of health problems could be solved by primary care procedures by general practitioners. 2. Fifteen percent of health problems need secondary medical procedures by a specialist. C. Medical cost Concidering the economic situation in rural area the amount of 2,062 won per residents during a year will be burdensome, so financial assistance is needed gorvernment to solve health and medical care problems for rural people.

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일부 농촌지역 거주 노인들에 대한 포괄적 노인평가 (Comprehensive Geriatric Assessment for Community Living Elderly in a Rural Area)

  • 이정애;신희영;정은경;신준호
    • 농촌의학ㆍ지역보건
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    • 제27권1호
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    • pp.21-31
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    • 2002
  • 일부 농촌 지역사회 거주 노인들의 신체적, 정신적, 기능적, 사회환경적 상태를 포함하는 포괄적 노인평가를 시행하여 지역사회 중심 노인보건사업의 기초자료를 얻고자 하였다. 전라남도 일개 군에서 층화 집락추출한 지역사회 거주 65세 이상 노인 388명을 대상으로 조사를 하였다. 조사내용은 노인들의 인구사회학적 특성, 현병력, 신체적, 정신적 건강상태, 일상생활활동(ADL), 도구적 일상생활활동(IADL) 및 대상노인들의 사회적, 환경적 평가를 포함하였다. 주요 연구결과는 다음과 같다. 1. 전체 388명 중 남자가 169명(43.6%)이었고 여자가 219명(56.4%)이었으며, 평균연령은 남자 $73.5{\pm}6.4$세, 여자 $74.0{\pm}6.2$세였다. 2. 조사노인 1인당 평균 1.6개의 질환을 가지고 있었으며, 3개 이상의 질환을 가지고 있는 노인들은 약 19%나 되었다. 3. 신체적 건강상태는 시각기능의 감소가 남녀 각각 50.9%, 65.3%로 다른 기능에 비해 가장 많았고, 씹거나 삼키는 데 어려움이 있는 구강기능의 감소도 34.3%, 39.3%로 그 다음을 차지하였으며, 상대적으로 상지, 하지 기능의 감소는 1-6% 정도로 적은 편이었다. 4. 정신적 건강상태는 단기 기억력으로 살펴 본 인지기능의 감소가 33.7%, 44.7%로 적지 않았고, 노인우울 평가를 이용하여 우울증 여부를 조사한 결과 남자에서 19.1%, 여자에서 24.9%이었다. 5. 일상생활활동(ADL) 평가 결과 6가지 모두 독립적으로 수행할 수 있는 노인이 남자 72.2%, 여자 58.9% 이었으며, 도구적 일상생활활동(IADL)은 식사준비하기가 가능한 경우가 남자에서 81.1%로 여자의 92.7%에 비해 낮았고, 반대로 금전관리가 가능한 경우는 여자에서68.9%로남자의 83.5%에비해낮았다. 6. 사회적 지지체계의 평가에서는 도움이 필요할 때 제공할 수 있는 수발자가 있는 경우가 26.3%이었고, 수발자와의 관계는 배우자가 가장 많고 다음은 며느리 였다. 가족과의 거주형태별로는 49.5%가 노부부만 사는 경우였고, 다음은 노인 혼자 사는 경우로 22.9%를 차지하였다. 환경적 평가에서는 위험요소 네 가지 중 하나이상을 가진경우가83.5%나되었다. 따라서 농촌지역 거주 노인들에 대한 포괄적 평가는 지역사회 중심 노인보건프로그램을 개발하기 위한 기초자료를 제공하였다.

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병원 전 단계 응급의료서비스 개선을 위한 구급활동일지 (Analysis of Prehospital Care Report for Improving Emergency Service at Prehospital Phase)

  • 최길순;김윤경
    • 한국응급구조학회지
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    • 제11권3호
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    • pp.163-174
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    • 2007
  • Purpose : This study analyzes prehospital care report of emergency service at prehospital stage, examines characteristics of activities of 119 paramedics and its users and aims to provide help for improving emergency system in future. Methods : Data collected were 119 prehospital care report and hospital records with 7,160 patients to emergency room by 119 ambulance from Jan. 1 to Dec. 31, 2006 and percentage and frequency of the data were obtained. Results : 1) Use of emergency room by 119 ambulance was increased in summer and autumn such as August(9.1%), September(11.2%) and October(13.5%) and it was more frequently used on Monday(17.3%), Saturday(17.2%) and Friday(16.1%) by telephone(98.6%). 2) Using emergency room was most in over sixties(51.8%), men(64.2%), community residents (78.3%), by report of family(50.3%) and at '09:01~12:00'(16.5%). 3) Symptoms of emergency room users included headache, chest pain, stomachache, lumbago and others as 40.6% and places where patients were found were at home(60.1%) due to chronic internal diseases at 49.2%. 4) Most of non-emergency patients(80.2%) arriving at hospital had normal pupil condition (88.4%) and clear consciousness(71.2%) and most of them left hospital after having first-aid treatment. 5) Physiological symptom tests evaluated by paramedics at prehospital stage included blood pressure(56.6%), pulse(22.9%), breathing(13.0%) and temperature(9.2%), and there was no SPo2 case. 6) Classification of severity by paramedics showed difference as emergency patients(18.0%) by paramedics and those(24.9%) by hospital. 7) First-aid treatments by paramedics at prehospital stage were promoting comfort(28.9%), hemostasis(7.7%), fixing cervical vertebrae(4.0%) and ensuring vein route(3.1%). 8) Selectors of medical agency were patients or guardians(86.2%) and emergency medical technicians(73.6%). Conclusion : To sum up the above research, it was found that percentage of using 119 ambulance by non-emergency patients was higher and paramedics performed basic first-aid treatment rather than professional first-aid treatment due to several conditions such as legal problems, range of allowance, etc. Therefore, it is considered that method to reduce frequency of ambulance by non-emergency patients and approaches to alleviate limitations of allowance of paramdeics to make them perform effective first-aid treatment at prehospital stage should be sought in the dimension of individual, organization and government.

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게르마늄강화효모의 게르마늄결합 단백질의 분리 및 확인에 관한 연구 (Study on Identification and Purification of Germanium-fortified Yeast)

  • 이성희;이상광;이현주;이용섭;박은우
    • Applied Biological Chemistry
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    • 제49권1호
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    • pp.55-59
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    • 2006
  • 본 연구는 게르마늄 강화 효모의 제조 공정을 위한 최적의 조건을 확인하고 제조된 게르마늄 강화 호모 내의 게르마늄 결합 상태 확인을 목적으로 수행하였다. 그 결과 영양소별 최적조건은 글루코스 3.0%, 효모추출물 0.3%, 펩톤 0.5%이었으며, 이 때 생성된 균체량은 67.4 mg/ml이었다. 또한 균체와 게르마늄 용액 혼합 비율은 1 : 0.5(50%), pH는 6.5 및 온도는 $35^{\circ}C$로 배양하는 조건이 높은 함량의 게르마늄을 효모 균체 내로 흡수시켜 게르마늄 강화 효모를 생산하는 것을 가능하게 하였다. 배양 과정을 통해 생산된 게르마늄 강화 효모는 배양 과정동안의 구조적 변화에 의해 효모 내에 흡수된 무기 형태인 $GeO_2$ 게르마늄과는 다른 구조를 나타내었다. 게르마늄 강화 효모는 효모 배양 과정을 통해 인체에 안전한 형태인 천연 유기 게르마늄을 형성하였다. 이는 각종 암, 성인병의 예방과 치료, 인체 면역력의 증진 등 건강 증진을 위한 새로운 기능성 원료로의 활용이 기대되며, 이에 대한 안전성 등의 지속적인 연구가 필요할 것으로 사료된다.

Korean Asthma Guideline 2014: Summary of Major Updates to the Korean Asthma Guideline 2014

  • Kim, Deog Kyeom;Park, Yong Bum;Oh, Yeon-Mok;Jung, Ki-Suck;Yoo, Ji Hong;Yoo, Kwang-Ha;Kim, Kwan Hyung
    • Tuberculosis and Respiratory Diseases
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    • 제79권3호
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    • pp.111-120
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    • 2016
  • Asthma is a prevalent and serious health problem in Korea. Recently, the Korean Asthma Guideline has been updated by The Korean Academy of Tuberculosis and Respiratory Diseases (KATRD) in an effort to improve the clinical management of asthma. This guideline focuses on adult patients with asthma and aims to deliver up to date scientific evidence and recommendations to general physicians for the management of asthma. For this purpose, this guideline was updated following systematic review and meta-analysis of recent studies and adapting some points of international guidelines (Global Initiative for Asthma [GINA] report 2014, National Asthma Education and Prevention Program [NAEPP] 2007, British Thoracic Society [BTS/SIGN] asthma guideline 2012, and Canadian asthma guideline 2012). Updated issues include recommendations derived using the population, intervention, comparison, and outcomes (PICO) model, which produced 20 clinical questions on the management of asthma. It also covers a new definition of asthma, the importance of confirming various airflow limitations with spirometry, the epidemiology and the diagnostic flow of asthma in Korea, the importance and evidence for inhaled corticosteroids (ICS) and ICS/formoterol as a single maintenance and acute therapy in the stepwise management of asthma, assessment of severity of asthma and management of exacerbation, and an action plan to cope with exacerbation. This guideline includes clinical assessments, and treatment of asthma-chronic obstructive pulmonary disease overlap syndrome, management of asthma in specific conditions including severe asthma, elderly asthma, cough variant asthma, exercise-induced bronchial contraction, etc. The revised Korean Asthma Guideline is expected to be a useful resource in the management of asthma.

16주간의 태극권 운동이 남자 고령자들의 건강체력 및 신체조성에 미치는 영향 (The Effects of Health Fitness and Body Composition in Elderly Men for 16 Weeks of Tai Chi Exercise)

  • 김철우
    • 생명과학회지
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    • 제21권8호
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    • pp.1127-1133
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    • 2011
  • 본 연구는 65세 이상 79세 사이의 남자고령자를 대상으로 16주간의 태극권 운동프로그램을 통해 신체적, 생리적 변화를 살펴보았으며, 일상생활을 영위하기 위한 신체적, 생리적 건강의 척도가 될 수 있는 건강체력과 신체조성의 변화에 어떤 영향을 미치는지 그 효과를 분석한 결과 다음과 같은 결론을 얻었다. 건강체력 요인의 심폐지구력, 근지구력, 유연성, 평형성은 유의한(p<0.05) 영향을 미치는 것으로 나타났으며, 신체조성 요인의 이완기 혈압과 체지방, 제지방에서 유의한 영향을 미치는 것으로 나타났다. 태극권 운동프로그램이 고령화 시기에 건강체력과 신체조성 요인에서 긍정적인 변화를 가져옴으로써 건강체력관련 요인이 상당부분 개선된 것으로 나타났는데 이와 같은 긍정적인 변화는 남자고령자에 건강한 신체활동을 위해서는 체력을 증진, 유지시키는 것이 중요하다. 특히, 규칙적인 태극권 운동이 어느 정도 영향을 미치는지에 대한 생리학적 기전을 명확하게 규명하기 위해서는 연령별 및 성별에 따라 다양한 측면에서 검토 되어야 할 필요성이 있으며, 고령화 사회에 대비한 구체적이고도 현실적인 연구가 지속적으로 이루어져야 할 것으로 사료된다.