• Journal of Korean Neurosurgical Society
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• 제41권2호
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• pp.95-99
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• 2007

Objective : The purpose of this reports is to describe the influence of continuous external ventricular drainage [EVD] on delayed ischemic neurologic deficit [DIND] after early surgery in ruptured aneurysmal patients. Methods : The authors reviewed 229 patients with aneurysmal subarachnoid hemorrhage [SAH] who had been treated with clipping at a single institution between 1998 and 2004. Of these, 121 patients underwent continuous EVD [Group A] postoperatively, whereas 108 patients did not [Group B]. EVD was performed at ipsilateral Kocher's point and maintained 2 to 14 days postoperatively. Results : DIND occurred in 15.7% [19 cases] of patients in Group A, 25% [27 cases] from Group B [P value=0.112]. Compared with Group A, Group B was more likely to suffer acute symptom of DIND and showed poor response to 3- H therapy. Major symptoms of DIND in Group A were mild confusion [36.8%] and mild deterioration of mental state [26.3%], contrary to weakness of extremities [59.2%] in Group B. At discharge, Glasgow Outcome Scales [GOS] of Group A were : good recovery [63.2%], moderately disabled [21%], severely disabled [10.5%], dead [5.3%] and Group B : good recovery [48.1%], moderately disabled [37%], severely disabled [14.8%] and dead [0%]. Of 121 patients from group A, 35 patients [28.9%] suffered ventriculitis. Conclusion : Continuous EVD after aneurysmal clipping in patients with SAH reduced the risk of DIND and its sequelae, relieved its symptoms, and improved the outcome.

• Journal of Gastric Cancer
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• 제17권1호
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• pp.63-73
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• 2017

Purpose: Data on operable gastric cancer from India is sparse. The purpose of this study was to investigate the clinical details, histopathological demographics, and 5-year overall survival (OS) and disease free survival (DFS) associated with operable, non-metastatic gastric cancer in a dedicated upper gastrointestinal (GI) surgical unit in India. Materials and Methods: Data for patients diagnosed with operable gastric cancer between January 2006 and December 2014 were retrospectively analyzed. Data were collected from electronic hospital records in addition to mail and telephonic interviews when possible. Results: A total of 427 patients were included. The tumor was located in the pyloro-antral region in 263 patients (61.7%). Subtotal gastrectomy was performed in 291 patients and total gastrectomy in 136 patients. Tumor stage classification revealed 43 patients (10.0%) with stage I, 40 patients (9.4%) with stage IIA, 59 patients (13.9%) with stage IIB, 76 patients (17.8%) with stage IIIA, 96 patients (22.5%) with stage IIIB, and 113 patients (26.4%) with stage IIIC disease. Follow-up data were available for 71.6% of the patients with a mean duration of 32.4 months. Five-year DFS and OS were 39% and 59%, respectively. Conclusions: Despite presenting at an advanced stage, the 5-year DFS and OS of patients with operable gastric cancer treated at a dedicated upper GI unit of a tertiary care center in India was good.

• Tuberculosis and Respiratory Diseases
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• 제66권1호
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• pp.42-46
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• 2009

폐암의 자연적 퇴화는 매우 드문 질환이다. 아직 그 기전은 불분명하다. 그러나 신체의 면역반응이 중요한 역할을 하는 것으로 알려져 있다. 이에 본 저자들은 폐의 편평 세포암 환자에서 항암치료 및 방사선 치료 등을 하지 않은 상태에서 자연적 퇴화가 발생한 증례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제77권1호
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• pp.38-41
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• 2014

Malignant rhabdoid tumor was first discovered in the kidney, and rhabdoid tumor of the lung was first reported in 1995. These were included as the variants of large-cell carcinoma, according to the 1999 World Health Organization classification of lung tumors. The rhabdoid tumor of the lung exhibits aggressive biological behavior and has a poor prognosis, and only a few reports of this tumor exist. We report a case of lung carcinoma with a rhabdoid phenotype, initially misdiagnosed as an aspergilloma, in a 48-year-old man who presented with recurrent hemoptysis. The chest computed tomography scans showed a huge consolidative lesion with an air crescent sign in the left upper lung and no contrast-enhancing lesion. An aspergilloma was diagnosed by the radiologist. However, after surgical excision and pathological examination, rhabdoid carcinoma was diagnosed. A surgical resection helps to make it possible to pathologically distinguish a malignancy from an aspergilloma.

• Journal of Korean Neurosurgical Society
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• 제41권6호
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• pp.397-402
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• 2007

Objective : Balloon cells and dysplastic neurons are histopathological hallmarks of the cortical tubers of tuberous sclerosis complex [TSC] and focal cortical dysplasia [FCD] of the Taylor type. They are believed to be the epileptogenic substrate and cause therapeutic drug resistant epilepsy in man. P-glycoprotein [P-gp] is the product of multidrug resistance gene [MDR1], and it maintains intracellular drug concentration at a relatively low level. The authors investigated expression of P-gp in balloon cells and dysplastic neurons of cortical tubers in patients with TSC. Methods : An immunohistochemical study using the primary antibody for P-gp, as an indicative of drug resistance, was performed in the cortical tuber tissues in two patients of surgical resection for epilepsy and six autopsy cases. Results : Balloon cells of each lesion showed different intensity and number in P-gp immunopositivity. P-gp immunopositivity in balloon cells were 28.2%, and dysplastic neurons were 22.7%. These immunoreactivities were more prominent in balloon cells distributed in the subpial region than deeper region of the cortical tubers. Capillary endothelial cells within the cortical tubers also showed P-gp immunopositivity. Conclusion : In this study, the drug resistance protein P-glycoprotein in balloon cells and dysplastic neurons might explain medically refractory epilepsy in TSC.

• 기독교교육논총
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• 제67권
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• pp.267-299
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• 2021

본 연구의 목적은 신자유주의 특성과 교육의 한계를 논의하면서 이에 대응하는 차원에서 기독교교육의 역할을 제시하는 데 있다. 신자유주의는 시장을 유토피아로 전제하면서 완전한 시장 질서에 모든 것을 맡기는 경제우선주의 사상이다. 이는 단순히 하나의 경제원리에만 머물지 않고 인간 삶의 모든 영역에 영향을 주면서 특히 자본주의와 연결하여 종교성을 나타낸다. 여기에 속한 인간은 신자유주의 시장에 맞는 유연한 노동력으로 이해된다. 그런 까닭에 신자유주의는 교육의 도구화 현상, 자유와 평등에 대한 왜곡, 전통적 가치에 대한 상실, 그리고 정체성을 잃고 표류하는 인간상을 심화시킨다. 본 연구에서는 이런 점들을 비평적으로 논의하면서, 시장에 대하여 성경에 기초한 균형 잡힌 이해, 교육의 도구화 현상에 대응하여 교육 본연의 목적 회복, 그리고 기독교인간학에 기초한 통전적인 인간상 규명과 적용에 있어서 기독교교육의 역할을 제안하였다.

• 대한두개안면성형외과학회지
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• 제20권4호
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• pp.223-227
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• 2019

Background: Neurosensory changes are frequently observed in the patients with mid-face fractures, and these symptoms are often caused by infraorbital nerve (ION) damage. Although ION damage is a relatively common phenomenon, there are no established and objective methods to evaluate it. The aim of this study was to test whether trigeminal somatosensory evoked potential (TSEP) could be used as a prognostic predictor of ION damage and TSEP testing was an objective method to evaluate ION injury. Methods: In this prospective TSEP study, 48 patients with unilateral mid-face fracture (only unilateral blow out fracture and unilateral zygomaticomaxillary fracture were included) and potential ION damages were enrolled. Both sides of the face were examined with TSEP and the non-traumatized side of the face was used as control. We calculated the latency difference between the affected and the unaffected sides. Results: Twenty-four patients recovered within 3 months, and 21 patients took more than 3 months to recover. The average latency difference between the affected side and unaffected side was 1.4 and 4.1 ms for the group that recovered within 3 months and the group that recovered after 3 months, respectively. Conclusion: Patients who suffered ION damage showed prolonged latency when examined using the TSEP test. TSEP is an effective tool for evaluation of nerve injury and predicting the recovery of patients with ION damage.

• 한국콘텐츠학회논문지
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• 제21권6호
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• pp.456-465
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• 2021

최근의 한 보고서는 2020년대에 지구에게 가장 가능성이 높은 위협으로 기후 변화를 포함한 환경문제를 언급했다. 따라서 오늘날 환경문제는 단순히 어느 특정 지역이나 국가의 문제일 뿐만 아니라 미래의 문제, 그리고 우리가 현재 살고 있는 현재의 문제라는 인식이 필요하다. 기독교 내에서는 창조와 타락, 구속을 기본으로 하는 기독교 세계관을 바탕으로 환경문제에 대한 다양한 관심과 연구가 진행되어 왔다. 이러한 관심은 초기에는 주로 가톨릭 진영에서 시작되었지만, 점차적으로 세계교회협의회(WCC)를 비롯한 복음주의 기독교 진영에서도 지구적 돌봄을 기독교적 책임과 연계시키는 노력이 계속되고 있다. 이처럼 지구 돌봄에 대한 관심이 보다 확대되고 있는 시점에서 이 연구는 기독교 공동체를 향해 다음과 같이 제안했다. 첫째, 환경보호, 생태보존에서 생명신학으로의 전환이 필요하다. 둘째, 자연을 바라보는 생태학에 대한 이해의 전환이 필요하다. 셋째, 기독교적 차원에서는 세속적 환경주의와 차별화된 진정한 회복운동이 있어야 한다. 넷째, 교회는 하나님의 나라를 고대하면서도 이 땅에서 피조세계와 함께 진정한 공동체를 실현할 수 있는 사회를 구현할 수 있어야 한다.

• 기독교교육논총
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• 제72권
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• pp.25-48
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• 2022

연구 목적 : 본 연구는 "비판적 상관관계신학 유형"(쉐릴, 힐트너, 브라우닝), "해석학적 유형"(그룸, 거킨), "신앙공동체적 형성 유형"(웨스터호프, 켐벨) 등과 같은 20세기 후반에 등장한 실천신학의 대표적인 세 가지 모델에 대한 비판적 고찰이다. 연구 내용 및 방법 : 먼저, 각 유형별로 기독교교육학, 목회상담학, 그리고 설교학 분야에서 2-3명의 대표적 학자를 선별하여 중심 사상을 유형별 특징과 연관하여 논의하였다. 그리고 시대적 상황에 대한 응답, 신학과의 관계, 학제적 대화, 그리고 실천이라는 주제를 중심으로 각 유형들에 대한 비판적 평가를 시도하였다. 결론 및 제언 : 각 유형들에 대한 연구를 통하여 실천신학으로서 오늘의 기독교교육의 핵심 과제는 포스트 시대의 여러 도전에 대한 적극적 응답, 오늘의 다양한 신학과의 상호적 대화, 횡단적 합리성에 기초한 학제적 대화, 개인적, 교회적, 사회적, 공적, 생태적, 더 나아가 디지털 차원까지 포괄하는 기독교적 실천 개념의 정립 등임을 제안하였다.

• 대한두개안면성형외과학회지
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• 제25권1호
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• pp.27-30
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• 2024

Fungal sinusitis is relatively rare, but it has become more common in recent years. When fungal sinusitis invades the orbit, it can cause proptosis, chemosis, ophthalmoplegia, retroorbital pain, and vision impairment. We present a case of an extensive orbital floor defect due to invasive fungal sinusitis. A 62-year-old man with hypertension and a history of lung adenocarcinoma, presented with right-side facial pain and swelling. On admission, the serum glucose level was 347 mg/dL, and hemoglobin A1c was 11.4%. A computed tomography scan and a Waters' view X-ray showed right maxillary sinusitis with an orbital floor defect. On hospital day 3, functional endoscopic sinus surgery was performed by the otorhinolaryngology team, and an aspergilloma in necrotic inflammatory exudate obtained during exploration. On hospital day 7, orbital floor reconstruction with a Medpor Titan surgical implant was done. In principle, the management of invasive sino-orbital fungal infection often begins with surgical debridement and local irrigation with an antifungal agent. Exceptionally, in this case, debridement and immediate orbital floor reconstruction were performed to prevent enophthalmos caused by the extensive orbital floor defect. The patient underwent orbital floor reconstruction and received intravenous and oral voriconazole. Despite orbital invasion, there were no ophthalmic symptoms or sequelae.