• The Journal of Pediatrics of Korean Medicine
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• v.27 no.4
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• pp.77-86
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• 2013

Objectives Allergic purpura is frequent disease in children. The purpose of this study is to analyze traditional Chinese medicine treatments of Allergic purpura in children through traditional Chinese medical journal research. Methods 22 studies were selected based on title keyword "Allergic purpura" "Child" published in CAJ (China Academic Journal). The studies were about clinical effect, herbs, injections, treatments, and nursing in Allergic purpura in children. Results & Conclusions There are so many treatments studied on purpura in children based on CAJ. A Single or combination traditional Chinese medicine treatment is effective in Allergic purpura in children. Therefore, we need to study more about Allergic purpura in children and should make more clinical cases about it.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.35 no.2
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• pp.28-48
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• 2022

Objectives : The purpose of this study is to investigate the trend of traditional Chinese medicine for sudden sensorineural hearing Loss(SSHL) in Chinese journals. Methods : Chinese National Knowledge Infrastructure(CNKI) and Wanfang med online were used to search randomized controlled trials(RCTs) on SSHL which were published from January, 2017 to December, 2021. Results : Among Chinese studies, Tonifying and Replenishing medicinal(補益藥) and Exterior-releasing medicinal(解表藥) were the most frequently used medicine in treating SSHL. Acori Graminei Rhizoma(石菖蒲) was the most frequently used herb excluding Glycyrrhizae Radix(甘草). All studies reported that using Traditional Chinese Medicine alone or combining western medicne(WM) is more effective for treating SSHL than using WM alone, although one study reported the result is not statistically significant. Conclusions : In analysis of selected studies, co-treatment of traditional chinese medicine and WM can be more effective way for treating SSHL than using WM alone. Side effects of treating SSHL can also be reduced by co-treatment of traditional chinese medicine and WM.

• The Journal of Korea CHUNA Manual Medicine
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• v.5 no.1
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• pp.169-181
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• 2004

Fibromyalgia(FMS) is a heterogeneous construct of chronic and widespread musculoskeletal pain that is frequently associated with sleep difficulties, fatigue, and other adjunctive symptoms. This article aims to review the literature on the theory and treatment for fibromyalgia in the chinese language article. chinese language aricles In wanfang data between 2001 and 2004 were reviewed. this result of research demonstrate that Acupuncture, Negative Pressure Therapy(Buhang), the Electrical Acupuncture Stimulation Therapy. Acupoints TENS are applied to treatment for fibromyalgia and these therapic managements of chinese medicine are more effective than western drug treatment.

• Journal of Society of Preventive Korean Medicine
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• v.7 no.1
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• pp.67-77
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• 2003

This study is to compare health related behaviors among Chinese, Korean Chinese in a Yanbian Province with a population of mainly Korean descendents and Koreans in Kangwon Province, Korea. Cross-sectional surveys were used to identify self-rated health, smoking, alcohol use, exercise and other lifestyle variables. A total of 739 Chinese, 663 Korean Chines, and 639 Koreans were surveyed using self-administered questionnaires. Few Korean Chinese(13.9%) reported they were healthy compared with Chinese(38.7%) and Koreans(36.3%). There was no difference in the prevalence of smoking by ethnic groups. More Koreans(48.5%) and Chinese Koreans(44.5%) reported drinking alcohol compared with Chinese(37.2%)(p < .001). Compared Chinese and Korean Chinese, fewer Koreans reported regular diet, exercise, health screening, and deep sleeping patterns. The lifestyle variables that affect the prevalence of disease were different by ethnic groups. In conclusion, ethnicity was shown to be an independent factor in relation to self-rated health, alcohol use, and other health lifestyle behaviors.

• Journal of Ginseng Research
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• v.47 no.2
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• pp.218-227
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• 2023

Background: Myocardial fibrosis (MF) is an advanced pathological manifestation of many cardiovascular diseases, which can induce heart failure and malignant arrhythmias. However, the current treatment of MF lacks specific drugs. Ginsenoside Re has anti-MF effect in rat, but its mechanism is still not clear. Therefore, we investigated the anti-MF effect of ginsenoside Re by constructing mouse acute myocardial infarction (AMI) model and AngII induced cardiac fibroblasts (CFs) model. Methods: The anti-MF effect of miR-489 was investigated by transfection of miR-489 mimic and inhibitor in CFs. Effect of ginsenoside Re on MF and its related mechanisms were investigated by ultrasonographic, ELISA, histopathologic staining, transwell test, immunofluorescence, Western blot and qPCR in the mouse model of AMI and the AngII-induced CFs model. Results: MiR-489 decreased the expression of α-SMA, collagenI, collagen III and myd88, and inhibited the phosphorylation of NF-κB p65 in normal CFs and CFs treated with AngII. Ginsenoside Re could improve cardiac function, inhibit collagen deposition and CFs migration, promote the transcription of miR-489, and reduce the expression of myd88 and the phosphorylation of NF-κB p65. Conclusion: MiR-489 can effectively inhibit the pathological process of MF, and the mechanism is at least partly related to the regulation of myd88/NF-κB pathway. Ginsenoside Re can ameliorate AMI and AngII induced MF, and the mechanism is at least partially related to the regulation of miR-489/myd88/NF-κB signaling pathway. Therefore, miR-489 may be a potential target of anti-MF and ginsenoside Re may be an effective drug for the treatment of MF.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.6
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• pp.1383-1389
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• 2008

This paper investigates the attitudes of medical users toward Korean oriental medicine and traditional Chinese medicine and their future demand. The subjects are 404 university students both in Korea and in China. The items that were questioned in this paper were the attitudes toward Korean oriental medicine and traditional Chinese medicine, the experience of using the medicine, the reason they used the traditional medicine, the factors that made them satisfied with the medicine, and the future plan for using the traditional medicine. The reason the university students were selected as subjects was that they have more possibilities as future users of the traditional medicine. This paper show that Chinese students have more positive attitude toward the traditional medicine than Korean students. The Koreans' experience rate of using the traditional medicine was comparatively high and the subjects in both the countries used the western medicine for the symptoms of a cold and dental problems. For the illness of stomach, Korean and Chinese subjects used the traditional medicine and the western medicine half and half. This paper presented the subjects with the common 14 diseases that they can have and asked which medicine they will use when they have the diseases. The results of analysis indicate that the subjects tend to use different medical institution according to the diseases. The subjects in Korea and China selected different medical institution for the same disease. From the analysis of the questionnaire, it can be seen that there are some differences between Koreans and Chinese in using the medical institution, which results from the difference in medical culture and the relationship between the traditional medicine and medical users could be figured out.

• The Journal of Pediatrics of Korean Medicine
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• v.30 no.3
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• pp.52-60
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• 2016

Objectives The purpose of this study is to analyze studies about the effects of topical application of Chinese herbal medicine for allergic rhinitis within randomized controlled trials (RCT). Methods The search database includes KJTK (Korean Traditional Knowledge Portal), OASIS (Oriental Medicine Advanced Searching Integrated system), CNKI (China National Knowledge Infrastructure), PubMed, and EMBASE. We used the following key search terms: "allergic rhinitis", "traditional Chinese medicine", "traditional Korean medicine", "Chinese herbal medicine", "randomized controlled trial", "clinical study", "nasal spray", and "nasal drop" Results Five studies were selected for analysis. Three studies used nasal spray of Chinese herbal medicine and two studies used nasal drops of Chinese herbal medicine for the intervention. Frequently used herbs were Magnoliae Flos (辛夷), Scutellariae Radix (黃芩), Coptidis Rhizoma (黃連), and Astragali Radix (黃芪). For the outcome measures, studies used symptom score, questionnaire of Quality of Life, nasal airway resistance, or laboratory studies. From all 5 studies, it has been shown that topical application of Chinese herbal medicine was effective for improving symptoms of allergic rhinitis. Two out of five studies showed statistical difference between study group and control group. Conclusions This study shows that topical application of Chinese herbal medicine can improve symptoms of allergic rhinitis. Well-designed RCT studies with low risk of bias and studies with outcome measures for assessing the immunomodulatory effects are necessary to confirm these findings.

• Journal of Korean Medical classics
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• v.23 no.1
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• pp.321-324
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• 2010

There are lots of disease names which contain the Chinese character "Gwol"(厥) in "Hwangjenaegyeong(黃帝內經)". Some of them are similar or identical to "Gwol"(厥) in today's Chinese Medical Science, but the rest can't be summed up with the meaning of today's "Gwol"(厥). The names which contain the Chinese character "Gwol"(厥) in "Hwangjenaegyeong(黃帝內經)"had been revised constantly in the later course of rectification of names. In the article, the names of disease which contain the Chinese character "Gwol"(厥) in "Hwangjenaegyeong(黃帝內經)"would be identified as referring to definite diseases by comparing with each other.

• Journal of Microbiology and Biotechnology
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• v.31 no.9
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• pp.1295-1304
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• 2021

Modified Renshen Wumei decoction (MRWD), a famous traditional Chinese medicine, is widely used for treating persistent diarrhea. However, as the mechanism by which MRWD regulates diarrhea remains unknown, we examined the protective effects of MRWD on intestinal barrier integrity in a diarrhea model. In total, 48 male rats were randomly distributed to four treatment groups: the blank group (CK group), model group (MC group), Medilac-Vita group (MV group) and Chinese herb group (MRWD group). After a 21-day experiment, serum and colon samples were assessed. The diarrhea index, pathological examination findings and change in ᴅ-lactate and diamine oxidase (DAO) contents illustrated that the induction of diarrhea caused intestinal injury, which was ameliorated by MV and MRWD infusion. Metabolomics analysis identified several metabolites in the serum. Some critical metabolites, such as phosphoric acid, taurine, cortisone, leukotriene B4 and calcitriol, were found to be significantly elevated by MRWD infusion. Importantly, these differences correlated with mineral absorption and metabolism and peroxisome proliferator-activated receptor (PPAR) pathways. Moreover, it significantly increased the expression levels of TLR4, MyD88 and p-NF-κB p65 proteins and the contents of IL-1 and TNF-α, while the expression levels of occludin, claudin-1 and ZO-1 proteins decreased. These deleterious effects were significantly alleviated by MV and MRWD infusion. Our findings indicate that MRWD infusion helps alleviate diarrhea, possibly by maintaining electrolyte homeostasis, improving the intestinal barrier integrity, and inhibiting the TLR4/NF-κB axis.

• Journal of Korean Academy of Nursing
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• v.51 no.6
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• pp.746-757
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• 2021

Purpose: The purpose of this study was to explore the factors influencing the occupational attitudes of nursing students in the probation period. Methods: Nursing students in the probation period from five hospitals completed an anonymous survey. The instruments included the nursing occupational attitude scale, family adaptability, partnership, growth, affection, and resolve index, and perceived social support scale. The study examined the moderation model between family function, perceived social support, and occupational attitudes using PROCESS 3.2. Results: For nursing students, when social support was low, family function had a significant positive impact on occupational attitudes and intentions, and the effect was much higher than that of perceived social support. Conclusion: Family function has a significant positive explanatory effect on attitude and intention (β = .13, p < .001 and β = .12, p < .001); the interaction term between family function and perceived social support are significant (β = .01, p < .001 and β = .01, p < .001). Perceived social support has a significant moderating effect on the relationship between family function and occupational attitudes of nursing students in the probation period. Family function has a significant difference in the occupational attitudes and intentions of nursing students with low perceived social support. Nursing students perceive social support in the probation period has a significant moderation effect in the relationship between their family function and occupational attitudes. Interns with low family function should be given more social support to improve their occupational attitudes.