• 한국정밀공학회지
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• 제29권8호
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• pp.824-833
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• 2012

The shrinkage and the warpage of the moulded part are influenced by the design of the product and injection mould. In a flat part with a partly thick volume, the warpage of the flat part is created from the difference of the shrinkage between thin and thick regions. The warpage of the flat part with a partly thick volume can be reduced by a proper design of the cooling system in the injection mould. The goal of this paper is to design properly cooling channels of injection mould to manufacture a flat part with a partly thick volume. The conformal cooling channel is adopted to improve cooling characteristics of a region with the thick volume. The linear cooling channels are assigned to the other region. The proper design of the conformal cooling channels is obtained from three-dimensional injection molding analysis for various design alternatives. The moulding characteristics of the designed mould with both conformal and linear cooling channels are compared to those of the mould with linear cooling channels from viewpoints of temperature, shrinkage and warpage of the moulded part using numerical analysis. Injection mould with both conformal and linear cooling channels for the flat part with a partially thick volume is fabricated. In addition, injection moulding experiments are performed using the fabricated mould. From the results of the injection moulding experiments, it has been shown that the designed mould can successfully fabricate the flat part with a partially thick volume.

• 정보과학회 논문지
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• 제44권9호
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• pp.887-892
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• 2017

뇌-컴퓨터 인터페이스는 정신 작업 동안 다채널에서 생성된 뇌파의 신호를 측정, 분석하여 컴퓨터를 제어하거나 의사를 전달하는 기술이다. 이때 최적의 뇌파 채널 선택은 뇌-컴퓨터 인터페이스의 편의성과 속도뿐만 아니라 정확도 향상을 위해 필요하다. 최적의 채널은 중복 채널들 또는 노이즈 채널들을 제거함으로써 얻는다. 이 논문에서는 최적 뇌파 채널을 선택하기 위해 이중 filter-기반의 채널 선택 방법을 제안한다. 제안한 방법은 먼저 채널들 간의 중복성을 제거하기 위해 spearman's rank correlation을 사용하여 중복 채널들을 제거한다. 그 뒤, F score를 이용하여 채널과 클래스 라벨 간의 적합성을 측정하여 상위 m개의 채널들만을 선택한다. 제안한 방법은 클래스 라벨과 관련되고 중복이 없는 채널들을 사용함으로써 좋은 분류 정확도를 이끌어 낼 수 있다. 제안한 채널 선택 방법은 채널의 수를 상당히 줄임과 동시에 평균 분류 정확도를 향상시켰다.

• 수산경영론집
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• 제23권2호
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• pp.101-128
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• 1992

How to distribute fisheries catches from producer to consumer is very important for everybody joined fisheries marketing channels (FMC), because most people are influenced their revenue and expenditure through marketing channels. Many institutions in Korea after 1960's have tried to develop the rationalization of FMC, but they have not gotten the satisfactory results in general in spite of a lot fruits. Comparing with general manufacturing industry, the fisheries industry has some specializations in the marketing channels. It makes them unique structure included wholesale market system similiar to fresh (perishable) food market with expertised technology. Wholesale market collects, distributes the fisheries catches and evaluates in by auction or bidding without consideration of producer's opinion. It is very necessary institution to make a decision to equatible price for fresh food and to play an important role for marketing effectiveness with minimum total transation and with massed reserve among institutions. But it has two weak points to increase the marketing cost and to make products bad fresh (perishable). Therefore, both Producer and consumer want to find the direct channels not to pass through wholesale market and to get more profit. I wanted to explain what problems of traditional FMC are and why the direct channel is necessary as follows in this paper. Chapter II : The types and specialization of FMC Chapter III : The structure and problem of fisheries wholesale market channel Chapter IV Marketing cost of FMC and direct channel I suggested when the direct channel in FMC is designed, new planner must carry out marketing functions which are performanced by wholesaler, middle man and the joined members of auction at wholesale market. In view of consumption area, these functions are : (1) the finding of production partner to make a business ; (2) communication of information ; (3) collecting ; (4) distribution ; (5) selecting and grading ; (6) evaluating ; (7) financing and payment ; (8) organization, in view of consumption area. The government must support also the group or individual of new direct channels to succeed it with (1) furnishing of market information (2) supplying of land and facility (3) financing (4) feed-back of dierct channels totally (5) making an opportunity of communication between producer and consumer. I want to emphasize again wholesale market is necessary and important institution for equatible price of fresh food in spite of the its weak points. At the same time. the direct channels are necessary to reduce the marketing cost and to keep better fresh food.

• 대한기계학회논문집A
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• 제34권10호
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• pp.1487-1492
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• 2010

본 논문의 목적은 3 차원 사출성형해석을 통한 냉장고 플라스틱 서랍 제작용 사출성형 금형의 형상적응형 냉각수로 설계이다. 바람직한 형상적응형 냉각수로의 설계를 얻기 위하여 형상적응형 냉각수로의 직경과 위치가 사출성형 특성과 제품의 품질에 미치는 영향을 정량적으로 고찰하였다. 해석결과로부터 제품의 균일 냉각과 변형 최소화가 가능한 최적의 형상적응형 냉각수로의 설계를 도출할 수 있었다. 본 연구에서 제안된 사출성형 금형과 기존의 직선형 냉각수로의 사출성형 금형을 냉각/제품 제작 시간 및 제품 품질 측면에서 비교한 결과, 형상적응형 냉각수로를 가진 사출성형 금형이 제품의 생산성과 품질을 동시에 향상시킬 수 있음을 알 수 있었다.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2009년도 춘계학술대회 논문집
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• pp.373-373
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• 2009

Relative humidity, membrane conductivity and water activity are critical parameters of polymer electrolyte membrane fuel cells (PEMFC) for high performance and reliability. These parameters are closely related with temperature. Moreover, the ideal values of these parameters are not always identical along the channels. Therefore, the cooling channel design and its operating condition should be well optimized along the all location of the channels. In the present study, we have performed a numerical investigation on the effects of cooling channels on performance of a PEMFC. Three-dimensional Navier-Stokes equations are solved with the energy equation including heat generated by the electrochemical reactions in the fuel cell. The present numerical model includes the gas diffusion layers (GDL) and serpentine channels for both anode and cathode gas flows, as well as cooling channels. To accurately predict the water transport across the membrane, the distribution of water content in the membrane is calculated by solving a nonlinear differential equation with a nonlinear coefficient, i.e., the water diffusivity which is a function of water content as well as temperature. Main emphasis is placed on the heat transfer between the solid bipolar plate and coolant flow. The present results show that local current density is affected by cooling channels due to the change of the oxygen concentration and the membrane conductivity as well as the water content. It is also found that the relative humidity is influenced by the generated water and the gas temperature and thus it affects the distribution of fuel concentration and the conductivity of the membrane, ultimately fuel cell performance. Unit-cell experiments are also carried out to validate the numerical models. The performance curves between the models and experiments show reasonable results.

• 동의생리병리학회지
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• 제18권2호
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• pp.396-400
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• 2004

The oriental medical doctors who had studied Shang Han Run thought highly of meridians and until now it was generally known that the chapter of heat in the Plain Questions of Emperor's Classic Internal Medicine(ECIM: 皇帝內經, 素門, 熱論) was the basis of Shang Han Run. The chapter of heat in the Plain Questions of ECIM was the first text in which the basic theory on six-channels according to the types of illness was introduced. In my point of view, the theory of treating six-channels had close relation to the Chapter of Channels in Miraculous Pivot of ECIM(皇帝內經, 靈樞ㆍ經脈篇) as well as the chapter of heat in the Plain Questions of ECIM. Therefore I took a look at the origin of treating six-channels in Shang Han Lun and illuminated again the meaning to compare the parts of in Shang Han Lun with the Chapter of Channels in Miraculous Pivot of ECIM. Conclusion : The symptoms of TaiYin-channel(太陰經) in the Chapter of Channels in Miraculous Pivot of ECIM were, for the most part, accord with those of TaiYin-disease in Shang Han Lun. Furthermore, the symptoms in Shang Han Lun were explained definitely and in detail. Therefore the theory of Shang Han Lun has been developed on the basis of ECIM with the changes of the times. TaiYin-disease implied symptoms of pi-spleen meridian(脾經) and fei-lung meridian(肺經). Therefore Shang Han Lun was the foundation of treatment based on overall analysis of signs and symptoms(辨證論治) in respect of meridian as well as the text in which the steps of infectious diseases(外感病) of human bodies were explained.

• 한국콘텐츠학회논문지
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• 제14권12호
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• pp.706-722
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• 2014

본 연구는 종합편성채널인 TV조선, JTBC, 채널A 3사와 KBS 영상뉴스의 뉴스 신뢰도 및 미디어 매체 신뢰도에 관한 수용자 인식을 비교분석한 것이다. 사전분석 결과 종합편성채널 TV조선, JTBC, 채널A의 영상뉴스가 지상파 KBS 보다 선정적이라는 것을 확인할 수 있었다. 이후 진행된 신뢰도 비교와 관련된 실험 연구에서는 종합편성채널인 TV조선, JTBC, 채널A의 영상뉴스가 KBS보다 3개 실험물 중 2개의 실험물에서 뉴스 신뢰도 및 매체 신뢰도 면에서 상대적으로 낮게 인식되고 있음을 알 수 있었다. 이상의 연구결과를 통해 종합편성채널의 뉴스 신뢰도 및 매체 신뢰도가 지상파보다 낮을 수 있음을 추론할 수 있었으며, 이는 영상뉴스의 선정성에 따라 영향을 받을 수 있음을 확인했다. 이 같은 결과는 방송 산업시장에서 종합편성채널의 가세로 격화된 경쟁구조, 그리고 이로 인해 과열된 현행 보도 방식에 대해 보다 깊은 논의가 이뤄져야 될 필요성과 향후 종합편성채널 영상뉴스의 보도방향에 대한 시사점을 제시한 결과로 판단할 수 있다.

• The Korean Journal of Physiology and Pharmacology
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• 제21권1호
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• pp.75-82
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• 2017

The effects of acepromazine on human ether-$\grave{a}$-go-go-related gene (hERG) potassium channels were investigated using whole-cell voltage-clamp technique in human embryonic kidney (HEK293) cells transfected with hERG. The hERG currents were recorded with or without acepromazine, and the steady-state and peak tail currents were analyzed for the evaluating the drug effects. Acepromazine inhibited the hERG currents in a concentration-dependent manner with an $IC_{50}$ value of $1.5{\mu}M$ and Hill coefficient of 1.1. Acepromazine blocked hERG currents in a voltage-dependent manner between -40 and +10 mV. Before and after application of acepromazine, the half activation potentials of hERG currents changed to hyperpolarizing direction. Acepromazine blocked both the steady-state hERG currents by depolarizing pulse and the peak tail currents by repolarizing pulse; however, the extent of blocking by acepromazine in the repolarizing pulse was more profound than that in the depolarizing pulse, indicating that acepromazine has a high affinity for the open state of the channels, with a relatively lower affinity for the closed state of hERG channels. A fast application of acepromazine during the tail currents inhibited the open state of hERG channels in a concentration-dependent. The steady-state inactivation of hERG currents shifted to the hyperpolarized direction by acepromazine. These results suggest that acepromazine inhibits the hERG channels probably by an open- and inactivated-channel blocking mechanism. Regarding to the fact that the hERG channels are the potential target of drug-induced long QT syndrome, our results suggest that acepromazine can possibly induce a cardiac arrhythmia through the inhibition of hERG channels.

• Asian-Australasian Journal of Animal Sciences
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• 제15권7호
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• pp.949-956
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• 2002

There are several physiological and pharmacological evidences indicating that opening of voltage dependent $Ca^{2+}$ channels play a critical role in induction of acrosome reaction in mammalian sperm. We determined the intracellular free $Ca^{2+}$ concentration in ejaculated goat sperm using a fluorescent, $Ca^{2+}$-specific probe, Fura2/AM, after the suspension of sperm in KRB medium, capable of sustaining capacitation and the acrosome reaction. We used nifedipine, D-600 and diltiazem, the $Ca^{2+}$ channel antagonists belonging to the classes of dihydropyridines, phenylalkylamines and benzothiazepines, to investigate the possibility that L-type voltage gated $Ca^{2+}$ channels play a role in the progesterone-stimulated exocytotic response. Progesterone promoted a rise in intracellular $Ca^{2+}$ in goat sperm and addition of nifedipine (100 nM) just prior to progesterone induction, significantly inhibited both intracellular $Ca^{2+}$ rise and exocytosis suggesting that $Ca^{2+}$ channels are involved in the process. However, the intracellular $Ca^{2+}$ increase during the process of capacitation was not affected with the addition of nifedipine suggesting a role of focal channel for $Ca^{2+}$ during capacitation. Studies using monensin and nigericin, two monovalent cation ionophores showed that an influx of $Na^+$ also may play a role in the opening of $Ca^{2+}$ channels. These results strongly suggests that the entry of $Ca^{2+}$ channels with characteristics similar to those of L-type, voltage-sensitive $Ca^{2+}$ channels found in cardiac and skeletal muscle, is a crucial step in the sequence of events leading to progesterone induced acrosome reaction in goat sperm.

• 혜화의학회지
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• 제13권1호
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• pp.61-69
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• 2004

I have come to next conclusions in consequence of documentary study about medical books of many generations regarding acupuncture and moxibustion therapy of arthalgia syndrome. 1. Jing point of regular channels is most used. Next there are extraordinary point, ashi point in the acupuncture and moxibustion therapy of arthalgia syndrome. 2. The gall baldder channel of foot-shaoyang is most used. Next there are the urinary bladder channel of foot-taiyang, the large intestine channel of hand-yangming, the stomach channel of foot-yangming, the small intestine channel of hand-taiyang, the spleen channel of foot-taiyin, the liver channel of foot-jueyin, the triple-warmer channel of hand-shaoyang, the du channel, the lung channel of hand-taiyin, the kidney channel of foot-shaoyin, the pericardium channel of hand-jueyin, the heart channel of hand-shaoyin, the ren channel in the order of frequency in used channel among the twelve channels. 3. Three yang channels of foot is most used. Next there are three yang channels of hand, three yin channels of hand, three yin channels of foot in the order of frequency in use among the twelve channels. 4. The gall baldder channel of foot-shaoyang is most used. Next there are the urinary bladder channel of foot-taiyang, the large intestine channel of hand-yangming, the triple-warmer channel of hand-shaoyang, the stomach channel of foot-yangming, the small intestine channel of hand-taiyang, the liver channel of foot-jueyin, the lung channel of hand-taiyin, the spleen channel of foot-taiyin, the kidney channel of foot-shaoyin, the du channel, the pericardium channel of hand-jueyin, the ren channel the heart channel of hand-shaoyin in the order of frequency in used point among the twelve channels. 5. Huantiao is most used. Next there are Weizhong, Quchi, Yangfu, Chize Feiyang Xiyangguan Xiguan Tianjing, Sanli Xiaoluo in the order of frequency in use. 6. Jing point in the order of frequency of use, expel wind-evil and remove wetness-evil on the Acupuncture and Moxibustion Therapy of Arthalgia Syndrome.