• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.5
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• pp.1315-1321
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• 2008

Chan-Su (Venenum bufonis) has long been for a variety of other purposes including treatment of inflammation in the folk medicine recipe. Since nitric oxide (NO) is one of the major inflammatory parameters, we first studied the effects of Chan-Su on NO production in lipopolysaccharide (LPS)-stimulated BV2 microglial cells, Chan-Su inhibited the secretion of NO in BV2 microglial cells, without affecting cell viability, The protein level of inducible nitric oxide synthase (iNOS) was decreased by Chan-Su, And Chan-Su also inhibited production of prostaglandin E2 (PGE2) and expression of cyclooxygenase (COX)-2. Proinflammatory cytokines, such as tumor necrosis factor $(TNF)-{\alpha}$, interleukin $(IL)-1{\beta}$ and IL-12, were inhibited by Chan-Su in a dose-dependent manner. And Chan-Su inhibited the degradation of ${IkB-\alpha}$, which was considered to be inhibitor of nuclear factor $(NF)-{\kappa}B$, one of a potential transcription factor for the expression of iNOS, COX-2 and proinflammatory cytokines. These results suggest that Chan-Su could exert its anti-inflammatory actions by suppressing the synthesis of NO through inhibition of $I{\kappa}B-{\alpha}$ degradation.

• Journal for History of Mathematics
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• v.27 no.1
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• pp.31-45
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• 2014

The book Su Hak Ip Mun(數學入門, Introduction to Mathematics) is one part of 5 sections of the book Seung Aeh Ill Chan(升厓日簒), which is a hand written manuscript in Chinese characters and the author and the date of writing is unknown. The book Seung Aeh Ill Chan begins with the song of division table so called Guguiga(九歸歌). We first investigate and compare the writing pattern of this with other old Korean mathematical books. Next, we investigate typical expression and calculation methods of mathematical contents and terminologies used in Su Hak Ip Mun and also figure out oddities of writing pattern of mathematical expression and cultural circumference of several problems dealt in the book. From these analysis and investigation, we estimate the writing date of Su Hak Ip Mun later than the year 1723 on which Su Ri Jeong On(數理精蘊) was first published. And we presumably guess that Guguiga and Su Hak Ip Mun are made not for practical use or theoretical purpose but for text to teach students.

• The Magazine of the IEIE
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• v.36 no.8
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• pp.875-884
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• 2009

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2007.05a
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• pp.102-104
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• 2007

• Ceramist
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• v.12 no.3
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• pp.77-84
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• 2009

• 전기의세계
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• v.59 no.10
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• pp.39-45
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• 2010

• 한국도로학회지:도로
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• v.10 no.4
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• pp.54-60
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• 2008

• 대한핵의학회:학술대회논문집
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• 2005.11a
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• pp.330.1-330.1
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• 2005

• The Bulletin of The Korean Astronomical Society
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• v.34 no.2
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• pp.24.1-24.1
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• 2009

• Bulletin of Korea Environmental Preservation Association
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• v.19 no.10
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• pp.2-8
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• 1997