• Journal of Veterinary Science
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• 제23권3호
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• pp.49.1-49.13
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• 2022

Background: Porcine circovirus type 2 (PCV2) and Mycoplasma hyopneumoniae (MHP) are economically significant pathogens in the pig industry. The use of combined vaccines against PCV2 and MHP is one of the most effective ways of protecting pigs from both diseases, and it has become a part of general management. Objectives: This study evaluated the efficacy of two new bivalent vaccines of PCV2 and MHP (Myco-X and Myco-XD) in SPF pigs. Myco-X and Myco-XD are a combined vaccine of MHP with PCV2b and PCV2d, respectively. Methods: Sixteen pigs were divided into four groups: Myco-X-vaccinated challenged, Myco-XD-vaccinated challenged, unvaccinated challenged, and unvaccinated unchallenged. Two milliliters of Myco-X were administered intramuscularly, and 0.5 mL of Myco-XD was injected intradermally at 3 wk of age. The pigs were challenged with virulent PCV2d via the intramuscular and intranasal route 4 wk post-vaccination. Results: All vaccinated pigs showed effective reduction of the clinical signs, the PCV2d load in the blood and nasal swab samples, as well as lung and lymphoid tissue lesions in the challenge test. Compared to unvaccinated challenged animals, the vaccinated challenged animals showed significantly higher (p < 0.05) levels of anti-PCV2 IgG, PCV2d-specific interferon-γ (IFN-γ), and anti-MHP IgG. Conclusions: Based on clinical, microbiological, serological, and pathological assessments, this study confirmed that both combined vaccines could protect pigs against PCV2 infection caused by PCV2d. On the other hand, further research on the efficacy evaluation of these new vaccines against the MHP challenge and PCV2d/MHP co-challenge is needed.

• Fisheries and Aquatic Sciences
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• 제25권4호
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• pp.243-249
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• 2022

Bacillus SW1-1 is a probiotic isolated from shrimp intestines. We investigated the effects of Bacillus SW1-1 coated diets on the growth, feed utilization, innate immunity, hematological parameters and resistance to Edwardsiella tarda in olive flounder (Paralichthys olivaceus). A commercial diet was used as the control (AP0) and two other diets were prepared by coating 0.25% (AP25) or 0.50% (AP50) probiotic powder which contains 1.0 × 10⁷ CFU/g Bacillus SW1-1. Four replicate groups of olive flounder (153 ± 2 g) were fed one of the diets for 12 weeks. Growth performance and feed utilization of the fish were not significantly affected by the dietary Bacillus SW1-1. After the challenge with E. tarda, AP50 group showed significantly higher survival than AP0 and AP25 groups. Innate immunity and anti-oxidant capacity of the fish were not significantly affected after the feeding trial. However, after the E. tarda challenge, the innate immune parameters (immunoglobulin, lysozyme and anti-protease) were significantly improved in fish fed AP25 and AP50 diets compared to those in fish fed AP0 diet. After the challenge test, significantly lower glucose level was observed in AP50 group compared to AP0 group. These results indicate that dietary supplementation of Bacillus SW1-1 could increase the disease resistance of olive flounder against E. tarda infection. The optimum coating levels of Bacillus SW1-1 needs to be further elucidated.

• 대한가정학회지
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• 제50권7호
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• pp.1-12
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• 2012

The purpose of this study was to identify the factor structure of self-efficacy, consumer behavior, and the learning effects of the unit 'Consumption Life' and to study the effects of self-efficacy on the consumer behavior, and the learning effects of the unit 'Consumption Life'. Questionnaires were administered to 370 female middle school students living in the Metropolitan City of Daegu. The data was analyzed by using the frequency, descriptive statistics, factor analysis, reliability analysis, multiple regression, and t-test. The findings are as follow. Self-efficacy was composed of five factors such as the capability in work performance, rational performance, fear, anxiety, and the ability to challenge oneself. Consumer behavior was composed of five factors such as emphasis on product display, emphasis on information, emphasis on fashion, emphasis on appearance, and the products/information exchange. The learning effects of the unit 'Consumption Life' was composed of two factors in the economical consumption, and rational consumption. The effects of consumer behavior and the learning effects of the unit 'Consumption Life' on each of the self-efficacy factors like the capability in work performance, rational performance, fear, anxiety, the ability to challenge oneself were explained by factors such as emphasis on product display, emphasis on information, emphasis on fashion, emphasis on appearance and products/information exchange, and economical consumption and rational consumption.

• 대한임베디드공학회논문지
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• 제14권6호
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• pp.329-338
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• 2019

Today's embedded software (SW) developments are mostly preceded by composing Software Requirement Specification (SRS). In particular, in the domain of weapon systems, it is essential to have a systematic method for the verification of the SW functionality. To be more specific, it is crucial to check if the SW functionality is implemented as described in SRS, so-called SW suitability verification. Unfortunately, existing static or dynamic SW testing methods are not sufficient to evaluate suitability with SRS since those testings only verify the robustness of the SW codes. In this paper, we propose an automatic embedded SW suitability verification framework which is based on a structured SRS. The major challenge in the automation of this verification framework is how to get rid of ambiguities in SRS. In order to overcome this challenge, we propose a structured SRS description framework and the supporting toolchain for that. We show how the proposed framework is applied to an actual SRS of a weapon system.

• 대한가정학회지
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• 제43권1호
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• pp.53-67
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• 2005

It has been suggested that children's reasons for reading are various; reading efficacy, challenge, curiosity, involvement, importance, recognition, competition, compliance, grades, avoidance and social interactions. To extend previous studies in which only one or two motivational constructs were studied in relation to reading abilities, this study was carried out to examine 11 inter-relationships of motivational constructs and their relationships to reading abilities. Using the MRQ of Wigfield & Guthrie(1997), and the Basic Learning Skills Test of the Korea Educational Development Institute(1989), 334 elementary school children were measured for their reading motivation and abilities. The results showed that 11 motivational constructs were interrelated, which were also related with reading abilities. Out of 11 motivational constructs, importance was able to predict the reading abilities in multiple-regression analyses. From F-tests, those groups with high reading efficacy, challenge, curiosity, involvement, recognition, competition and social interactions outperformed those with low motivational constructs. The findings of this study confirm that children read for various reasons, and internal motivation and social interactions are significantly related with reading abilities. It is proposed that the internal reasons for reading are also more significant factors in explaining reading abilities than external reasons. Finally, cultural influences on reading motivation and comprehension are also discussed.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1998년도 봄 학술발표회 논문집
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• pp.291-300
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• 1998

This paper demonstrates how ambient vibration measurements at a limited number of locations can be effectively utilized to estimate parameters of a finite element model of a large-scale structural system involving a large number of elements. System identification using ambient vibration measurements presents a challenge requiring the use of special identification techniques, which ran deal with very small magnitudes of ambient vibration contaminated by noise without the knowledge of input farces. In the present study, the modal parameters such as natural frequencies, damping ratios, and mode shapes of the structural system were estimated by means of appropriate system identification techniques including the random decrement method. Moreover, estimation of parameters such as the stiffness matrix of the finite element model from the system response measured by a limited number of sensors is another challenge. In this study, the system stiffness matrix was estimated by using the quadratic optimization involving the computed and measured modal strain energy of the system, with the aid of a sensitivity relationship between each element stiffness and the modal parameters established by the second order inverse modal perturbation theory. The finite element models thus identified represent the actual structural system very well, as their calculated dynamic characteristics satisfactorily matched the observed ones from the ambient vibration test performed on a large-scale structural system subjected primarily to ambient wind excitations. The dynamic models identified by this study will be used for design of an active mass damper system to be installed on this structure fer suppressing its wind vibration.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2021년도 춘계학술대회
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• pp.614-616
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• 2021

세계는 안구 질병 치료, 시력 회복 서비스, 훈련된 안과 전문의의 부족 등 안과 측면에서 어려움에 직면해 있다. 안구 병리를 조기에 발견하고 진단하면 시각 장애를 예방할 수 있다. 하지만 기존의 망막 영상 공개 데이터 세트는 임상에서 발견되는 다양한 질병으로 구성되어 있지 않기 때문에 다양한 안구 질환을 분류하는 방법을 개발하기가 어렵다. 본 연구는 2021 ISBI challenge에서 공개된 데이터 세트인 Retinal Fundus Multi-disease Image Dataset (RFMiD) 을 이용하여 안구 질환을 분류하는 방법을 제안한다. 본 연구의 목표는 망막 이미지를 정상, 비정상 범주로 선별하기 위한 강력하고 일반화 가능한 모델을 개발하는 것이다. 제안된 모델의 성능은 수신자 조작 특성 곡선 아래 면적 점수로 비공개 테스트 데이터 세트에 대해 0.9782의 값을 보여준다.

• Clinical and Experimental Reproductive Medicine
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• 제25권3호
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• pp.251-260
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• 1998

It is well known that the clinical test for responsibility of accurate fertilization capacity in male partners is very important to diagnose and treat the infertility. However, it has been reported that the traditional semen analysis cannot accurately predict fertilization and pregnancy potential. The present study was performed to evaluate the acrosomal reaction to ionophore challenge (ARIC) test as a prognostic indicator for fertilization of sperm and oocyte in an in vitro fertilization and embryo transfer (IVF-ET) program. From March 1996 to Februry 1997, 30 couples undergoing IVF program were allocated to this study group. All female partners in the study group were 35 years old or less and their serum level of basal follicle stimulating hormone (FSH) and estradiol $(E_2)$ were normal. All the male partners have normal parameters of semen analysis. The ARIC tests were performed on the day of ovum pick up and in vitro insemination in all the male partners. The controlled ovarian hyperstimulation (COH) using luteal long protocol of gonadotropin releasing hormone (GnRH) agonist was used in all couples for IVF-ET. The acrosomal reaction with $10{\mu}l$ of 10% DMSO was induced spontaneously in $10.1{\pm}9.8%$, and acrosomal reaction with calcium ionophore A 23187 was induced in $27.4{\pm}18.1%$, and the ARIC value was $17.4{\pm}16.2%$. There were no significant correlation between the ARIC value and the fertilization rate ($r^2$=0.044, p=0.268). There were also no significant correlation between the ARIC value and the percentage of the grade I, II embryos ($r^2$=0.046, p=0.261). On the basis of above results, it was suggested that ARIC test might not be a useful prognostic indicator for fertilization in IVF-ET in male partners with normal parameters of conventional semen analysis. We guessed that IVF-ET could be performed to the patients primarily without universal appilcation of ARIC test to all male partenrs, and if fertilization failure occurs, the micro assisted fertilization (MAF) such as intracytoplsmic sperm injection (ICSI) might be used as an alternative mode of treatment with acceptable success rate.

• 한국동물위생학회지
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• 제24권1호
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• pp.69-82
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• 2001

The result of studying the pathogenicity of Salmonella typhimurium and S enteritidis isolated from domestic animals in Gyeongbuk province were summarized as follows. In Congo-red binding test, S typhimurium had much more rough types than S enteritidis. In colicin production test, 4 strains of S typhimurium were positive but all of S enteritidis were negative. In hemolysin production test, all of S typhimurium and S enteritidis were negative. In Guinea pig serum resistant test, all of S typhimurium and S enteritidis were positive. As a result of pathogenicity test to mice, 54.4% of mice were died. Therefore, S typhimurium and S enteritidis were considered as highly pathogenic. S typhimurium DT104 and S enteritidis PT4 were more pathogenic to mice than other phage types of same serovar. S typhimurium and S enteritidis were considered not so pathogenic for 6-day-old chickens. The recovery rates of Salmonella stains from mice and chickens inoculated were 96.8%, and 54%, respectively. In chickens, proportional to the time from 2 weeks after challenge inoculation, the recovery rates were noticeably decreased.

• 한국수산과학회지
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• 제41권4호
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• pp.248-252
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• 2008

A 6-week feeding trial was conducted to investigate effects of dietary supplementation with wood vinegar (WV) as a feed additive for juvenile olive flounder, Paralichthys olivaceus. Eight experimental diets supplemented with 0(control), 0.01, 0.025, 0.05, 0.1, 0.25, 0.5 and 2.0% WV/kg diet($WV_0,\;WV_{0.01},\;WV_{0.025},\;WV_{0.05},\;WV_{0.1},\;WV_{0.25},\;WV_{0.5},\;and\;WV_{2.0}$, respectively) were prepared by mixing with basal diet. After the 6-week feeding trial, fish fed the $WV_{0.1}$ diet had significantly higher weight gain, feed efficiency, and specific growth rate than those of fish fed the other diets(P<0.05). No mortality was observed in the treatment groups fed the experimental diets for 6 weeks. The liver antioxidant activity of fish fed the $WV_{0.01},\;WV_{0.025},\;and\;WV_{0.05}$ diets was significantly higher than that of fish fed the other diets. The lysozyme activity of fish fed the $WV_{0.25}$ diet was significantly higher than that of fish fed the other diets. Fish fed diets supplemented with WV had significantly lower cumulative mortality than that of fish fed the control diet throughout the challenge test, and fish fed the $WV_{0.05}\;and\;WV_{0.1}$ diets had the highest resistance to disease caused by Edwardsiella tarda at day 7 of the challenge test. Therefore, feeding 0.05-0.1% WV/kg diet improves the growth and immune responses of juvenile olive flounder, Paralichthys olivaceus.