• Journal of Ginseng Research
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• v.39 no.1
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• pp.14-21
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• 2015

Background: Colorectal cancer is a leading cause of cancer-related death, and inflammatory bowel disease is a risk factor for this malignancy. We previously reported colon cancer chemoprevention potential using American ginseng (AG) in a xenograft mice model. However, the nude mouse model is not a gut-specific colon carcinogenesis animal model. Methods: In this study, an experimental colitis and colitis-associated colorectal carcinogenesis mouse model, chemically induced by azoxymethane/dextran sodium sulfate (DSS) was established and the effects of oral AG were evaluated. The contents of representative ginseng saponins in the extract were determined. Results: AG significantly reduced experimental colitis measured by the disease activity index scores. This suppression of the experimental colitis was not only evident during DSS treatment, but also very obvious after the cessation of DSS, suggesting that the ginseng significantly promoted recovery from the colitis. Consistent with the anti-inflammation data, we showed that ginseng very significantly attenuated azoxymethane/DSS-induced colon carcinogenesis by reducing the colon tumor number and tumor load. The ginseng also effectively suppressed DSS-induced proinflammatory cytokines activation using an enzyme-linked immunosorbent assay array, in which 12 proinflammatory cytokine levels were assessed, and this effect was supported subsequently by real-time polymerase chain reaction data. Conclusion: AG, as a candidate of botanical-based colon cancer chemoprevention, should be further investigated for its potential clinical utility.

• Journal of Korean Public Health Nursing
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• v.35 no.1
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• pp.135-148
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• 2021

Purpose: This study examined socio-demographic and health status factors associated with hazardous drinking in male and female elderly with hypertension. Methods: The sample consisted of 2,322 seniors with hypertension and was obtained from the Seventh Korean National Health and Nutrition Examination Survey (VII-1, VII-2, VII-3). Complex sample analysis was performed using the independent t-test, the Chi-square test and multiple logistic regression in SPSS/WIN 24.0 program. Results: The factors associated with hazardous drinking in the male hypertensive seniors were age (OR=2.13, CI=1.37-3.32), weekly drink number (OR=0.11, CI=0.07-0.16) and weight gain control (OR=0.44, CI=0.21-0.94), and corresponding factors in female hypertensive seniors were age (OR=4.56, CI=2.37-8.80), income level (OR=1.88, CI=1.05-3.37), weekly drink number (OR=0.09, CI=0.04-0.17), current smoking (OR=6.88, CI=2.29-20.64), weight loss control (OR=1.99, CI=1.14-3.47), hypertension treatment (OR=35.62, CI=2.02-629.43), and hypertension drug (OR=0.06, CI=0.01-0.61). Conclusion: Risk drinking in elderly with hypertension was found to be related to personal characteristics and health status. Therefore, to manage hypertension effectively in the elderly, drinking patterns should be improved and active participation in the practice of healthy activities such as weight control, smoking cessation, and decreased alcohol intake, should be encouraged.

• Journal of the Korea Convergence Society
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• v.9 no.12
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• pp.459-466
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• 2018

This study investigated a systematic literature review on local and international literatures focusing on Participatory Action Research(PAR), Community Based Participatory Research(CBPR) in workplace and community. Eighty percent of the 10 studies reviewed included research involving health professionals, community networks, workers, and university researchers. Health promotion programs varied from health and safety awareness, smoking cessation, diabetes management, physical activity, self-efficacy enhancement, cardiovascular disease, musculoskeletal disorders and mental health. PAR, CBPR are required to participate actively in research through community collaboration to promote health. We can solve problems at the community level. And identified sustainable effects when developing and implementing a health promotion program. PAR and CBPR are expected to continuously pursue change by adjusting the scope of individuals, organizations, communities, and institutional dimensions. They are also expected to be implemented for workers in the various workplace.

• Korea Journal of Hospital Management
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• v.24 no.2
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• pp.12-22
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• 2019

Purposes: The purpose of this study was to examine the association between risk behaviors and smoking in Korean adolescents. Methods: This study used data from online survey of youth health behavior in 2017. Data from a total of 54,411 people (27,139 male, 27,272 female) were included in the analysis. chi-square test, simple logistic regression, multiple logistic regression were performed using SAS 9.4. Findings: Multiple logistic regression analysis showed that risk behaviors such as drinking alcohol experience, sexual experience, drug use experience and high caffeine energy drinks intake experience had a significant effect on smoking. Adolescents with drinking experience were more likely to smoking than those who had no experience(OR=8.58, 95% CI: 7.67~9.60). Adolescents with sexual experience were more likely to smoking than those who had no experience(OR=4.47, 95% CI: 3.91~5.11). Adolescents with drug use experience were more likely to smoking than those who had no experience(OR=2.32, 95% CI: 1.63~3.32). Also, adolescents with high-caffeine energy drinks intake experience were more likely to smoking than those who had no experience(OR=1.37, 95% CI: 1.23~1.53). Practical Implications: All the risk behaviors were significantly associated with smoking rates. Results of this study suggest that physicians and health workers in medical institutions and health centers should simultaneously serve education and consultation for the smoking cessation as well as for the prevention of risk behaviors.

• Journal of the Korean society of biological therapies in psychiatry
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• v.24 no.3
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• pp.230-238
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• 2018

Objectives : Among adolescents, the proportion of daily smoking tends to increase with age, and does not return to the previous level. Therefore, we examined the factors associated with smoking frequency in a nationwide sample of Korean adolescents to help prevent the progression of smoking. Methods : Among 127,804 adolescents who participated in the 2016 and 2017 Korean Youth Risk Behavior Web-Based Survey, data from 7,781 adolescents who replied that they currently smoked were analyzed. According to the frequency of cigarette smoking, participants were classified into daily and non-daily smokers. Participants' socio-demographic characteristics, smoking behavior, and psychological problems including perceived stress, depressive mood, and suicidality were assessed. Results : There were 3,627(47.4%) daily smokers and 4,154(52.6%) non-daily smokers. Low parental educational level, and early smoking experience were positively associated with daily smoking. High academic achievement, and high socio-economic status were negatively associated with daily smoking. Daily smoking was positively associated with lower happiness, lower sleep satisfaction, and severe stress during the past 12 months. Factors affecting suicide attempts of smokers were sex, residential type, socioeconomic status, and early smoking experience. Conclusion : The results indicated that socially disadvantaged families, and smoking experience with young age influenced daily smoking among Korean adolescents. Daily smoking was associated with psychological problems including lower happiness, lower sleep satisfaction, and severe stress. Early smoking experience influenced suicidal attempts among Korean adolescent smokers. Early intervention for smoking cessation in this high-risk group may contribute to prevention of these psychiatric complications of smoking.

• Journal of Cancer Prevention
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• v.23 no.4
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• pp.176-182
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• 2018

Background: Family physicians (FPs) play an important role in cancer control. The aim of this study was to understand the functions of FPs in cancer control and to explore FPs' perceptions of their own roles and the difficulties they face in cancer control in Karabuk province, Turkey. Methods: The study consisted of two methodological parts. The qualitative part included a descriptive study in which data were collected from 87.5% (n=56) out of all FPs in Karabuk using a questionnaire. In the quantitative part, in-depth interviews with 15 FPs were conducted and analyzed through content analysis. Results: Half of the FPs (50.0%) provided cancer prevention information for their registered people, focusing on especially smoking cessation. In the last three months, the proportion of FPs who had not invited anyone to screenings was 37.5% for the pap test, 26.8% for the mammography, 19.0% for the fecal occult blood test and 34.5% for the colonoscopy. Only 16.1% of them reported that they made home visits for cancer patients. In the qualitative part of study, the following themes were highlighted: the perceived responsibilities of FPs regarding cancer control; the effect of geographically undefined working area of FPs; the issues with coordination between FPs and specialists; the effect of the number of primary care team members. Conclusions: Cancer control services provided by FPs have significant problems in terms of the FPs' approach to the services and their content, continuity and coordination.

• Journal of the Korea Convergence Society
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• v.10 no.9
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• pp.323-332
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• 2019

The purpose of this study was to examine the validity and reliability of the Revised Multidimensional Coping Scale(MCS-R) in university student who attended smoking cessation group therapy. Data were collected from 198 university students. Construct validity using exploratory factor analysis were conducted and convergent validity using Resilience scale, Patient Health Questionare-9(PHQ-9) were conducted. A Principal components analysis with varimax rotation and Kaiser normalization identified a thirteen-factor accounting for 69.7% of the variance in scores. Also, the internal consistency(0.66-0.94) and test-retest reliability was adequate(0.44-0.85) in all subscales of the MCS-R. The MCS-R has adequate psychometric characteristics so it can be used to verify.

• The Journal of the Korea Contents Association
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• v.19 no.9
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• pp.321-328
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• 2019

This study is to identify the factors related to smokers' intention to quit smoking and the differences between male and female smokers. We used data from Community Health Survey of 2017 and a total of 39,435 participated in the study. It was analyzed through IBM SPSS Statistics 23.0 to conduct frequency analysis and binary logistic regression analysis. We found that gender, age, marital status, education, household income, subjective health, attempts to quit smoking, exposure to quit smoking campaigns, education to quit smoking, and number of cigarettes per day are related to the smokers' intention to quit smoking. For male smokers, education and household income are relevant to their intention to quit smoking, unlike female smokers. The findings suggest that smoking cessation campaigns and education are necessary for smokers with low level of education or income. Further, it indicates that gender differences should be taken into consideration upon intervention program.

• Atmosphere
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• v.29 no.1
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• pp.41-51
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• 2019

The characteristics of the sea breeze were investigated using the wind and temperature data collected from 300-m tower at Boseong from May 2014 to April 2018. Sea breeze day was detected using following criteria: 1) the presence of a clear change in wind direction near sunrise (between 1 hour after sunrise and 5 hours before sunset) and sunset (from 1500 LST to midnight), 2) presence of thermal forcing of sea breeze and 3) no heavy precipitation (rain < $10mm\;d^{-1}$). Sea breeze days occurred on 569 days for 4 years. The monthly distribution of sea breeze day occurrence shows maxima in May and September and minimum in December. The average onset and cessation times of the sea breeze are 0942 LST and 1802 LST, respectively. Although the 10-m wind shows clockwise rotation with time in the afternoon, the observed hodograph does not show an ideal elliptical shape and has different characteristics depending on the upper synoptic wind direction. Vertical structure of sea breeze shows local maximum of wind speed and local minimum of virtual potential temperature at 40 m in the afternoon for most synoptic conditions except for southeasterly synoptic wind ($60^{\circ}{\sim}150^{\circ}$) which is in the same direction as onshore flow. The local minimum of temperature is due to cold advection by sea breeze. During daytime, the intensity of inversion layer above 40 m is strongest in westerly synoptic wind ($240^{\circ}{\sim}330^{\circ}$) which is in the opposite direction to onshore flow.

• Clinical and Experimental Otorhinolaryngology
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• v.11 no.4
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• pp.242-249
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• 2018

Objectives. Smoking is associated with hearing loss, while the correlation between tinnitus and smoking is not fully elucidated. This study aimed to evaluate risk factors of tinnitus in adolescents in terms of smoking, and we identified a rectifiable parameter that can be serially monitored. Methods. A cross-sectional study was conducted using data from the Korea National Health and Nutrition Examination Survey, with 2,782 participants aged 12 to 18 years, from 2008 through 2011. Participants with history of ear disease, hearing loss, and inadequate responses to questionnaires were excluded. We investigated the prevalence of tinnitus and tinnitus-related annoyance by questionnaire and sought potential risk factors in blood and urine tests and smoking history. Results. The prevalence of tinnitus in the 12- to 18-year-old population was 17.5%, with 3.3% reporting tinnitus-related annoyance. On univariate analysis, the prevalence of tinnitus increased with age (P<0.001) and was higher among girls (P=0.012). Blood tests and urinalysis showed significant correlation between tinnitus and red blood cell count, alkaline phosphatase levels, and urine cotinine (P=0.002, P<0.001, P=0.018, respectively). In multivariate analysis, the urine cotinine level was the only parameter associated with tinnitus (odds ratio, 1.000; 95% confidence interval, 0.999 to 1.000; P=0.038). Smoking was also significantly correlated with tinnitus (P=0.043), and amount of smoking with tinnitus-related annoyance (P=0.045). However, current smoking and past smoking were not correlated with tinnitus. Conclusion. Urine cotinine may be a rectifiable marker for management of tinnitus in adolescents. This suggests that smoking cessation should be incorporated in the management of tinnitus in adolescents.