• 제목/요약/키워드: cerebrovascular

검색결과 833건 처리시간 0.025초

Effects of Cardiotonic Pills® on Cerebrovascular CO2 Reactivity and Erythrocyte Deformability in Normal Subjects: A Pilot Study

  • Sang-Kwan Moon;Han-Gyul Lee;Seungwon Kwon;Seung-Yeon Cho;Seong-Uk Park;Woo-Sang Jung;Jung-Mi Park;Chang-Nam Ko;Ki-Ho Cho
    • 대한한의학회지
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    • 제44권4호
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    • pp.87-103
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    • 2023
  • Backgrounds and objectives: Cardiotonic Pills® (CP) are used for vascular diseases such as coronary diseases, atherosclerosis, and cerebral infarction. This study aimed to determine the transient effects of CP on cerebrovascular CO2 reactivity (CVR) and erythrocyte deformability in normal subjects. Methods: This study had a crossover design and included 10 participants who were randomly allocated to 2 groups. The experimental group was given CP with water, while the control group was given only water. CVR was measured by hyperventilation-induced CVR of the middle cerebral artery (MCA) using transcranial Doppler (TCD). Erythrocyte deformability was measured using a Rheoscan-D microfluidic ektacytometer. All measurements were performed prior to and 1, 2, and 3 hours after CP or water administration. Blood pressure and heart rate were also measured before and after administration. Results: CP significantly improved CVR 3 hours after administration in the experimental group compared to the control group (p = 0.042). The corrected blood flow velocity at partial pressure of end-tidal carbon dioxide (PETCO2) = 40mmHg (CV40) was also significantly improved 2 and 3 hours after administration in the CP group compared to the control group (p = 0.036 and p = 0.021, respectively). CP significantly improved erythrocyte deformability 3 hours after administration in the experimental group compared to the control group (p = 0.027). Mean heart rate and mean blood pressure showed no change. Conclusions: This study demonstrated that CP increases CVR and erythrocyte deformability. These results suggested that CP improves cerebral microcirculation which provide evidence for the future use of CP for prevention of ischemic stroke and neurodegenerative diseases.

컴퓨터 영상처리 방식을 이용한 정맥내 혈관 조영술 시스템 개발 (Digital Subtraction Technique for Intravenous X-ray Image System)

  • 이승지;이태수
    • 대한의용생체공학회:의공학회지
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    • 제2권2호
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    • pp.109-116
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    • 1981
  • The objective of this research is to develop the hardware and software systenls of the digital intravenous angiographic system. The system will be used in clinical diagnosis of cardiovascular and cerebrovascular diseases. By utilizing computer image processing technique and digital subtraction method, the system can decrease the patient's harzard and expenses in performing intravenous angiography, as compared with conventional angiograms of the arterial injection.

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Postpartum Cerebral Angiopathy - Presenting with Both Hemorrhagic and Ischemic Stroke

  • Kim, Sung-Ho;Chang, Chul-Hoon;Kim, Sang-Woo;Choi, Byung-Yon
    • Journal of Korean Neurosurgical Society
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    • 제38권4호
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    • pp.299-302
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    • 2005
  • Postpartum cerebral angiopathy[PPCA] is a benign and, reversible cerebrovascular disease in the postpartum period. The authors report here a 29-year-old woman who had severe headache, very poor consciousness and visual disturbances as the symptoms of PPCA. The clinical and radiological evaluation and treatment of this patient are disscussed.

Effect of Cadmium on cerebrovascular endothelial cells

  • Park, Eun-Kyung;Jung, Yi-Sook;Lee, Soo-Hwan;Baik, Eun-Joo;Moon, Chang-Kiu;Moon, Chang-Hyun
    • 한국환경독성학회:학술대회논문집
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    • 한국환경독성학회 2002년도 춘계학술대회(Genomics, Proteomics, and Risk Assesment):환경독성 및 위해성 평가 국제 심포지움
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    • pp.77-77
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    • 2002
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Massive cerebral venous sinus thrombosis secondary to Graves' disease

  • Son, Hye-Min
    • Journal of Yeungnam Medical Science
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    • 제36권3호
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    • pp.273-280
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    • 2019
  • Cerebral venous sinus thrombosis (CVT) is a rare cerebrovascular condition accounting for 0.5-1% of all types of strokes in the general population. Hyperthyroidism is associated with procoagulant and antifibrinolytic activity, thereby precipitating a hypercoagulable state that predisposes to CVT. We report the case of a 31-year-old Korean man with massive CVT and diagnosis of concomitant Graves' disease at admission. Early diagnosis and prompt treatment of CVT are important to improve prognosis; therefore, CVT should be considered in the differential diagnosis in all patients with hyperthyroidism presenting with neurological symptoms.

Dolichoectasia of vertebrobasilar artery presenting as facial pain: a case report

  • Prasanna Vadhanan
    • Journal of Dental Anesthesia and Pain Medicine
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    • 제23권4호
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    • pp.237-240
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    • 2023
  • Dolichoectasia of the intracranial arteries is a rare condition characterized by elongated and tortuous arteries due to progressive destruction of the vessel walls. Although most patients present with cerebrovascular accidents, our patient presented with intractable facial pain along the distribution of the trigeminal nerve. Clinical examination revealed involvement of the 5th, 7th, and 8th cranial nerves, and subsequent MRI showed dolichoectasia of the left basilar artery. The patient experienced symptomatic relief after a trial of carbamazepine along with botulinum toxin injections.