• Journal of Korean Biological Nursing Science
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• v.17 no.4
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• pp.324-330
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• 2015

Purpose: The purpose of this study was to analyze the trends in Korea of nursing research using animals. Methods: 45 articles were reviewed with descriptive statistics from 2000 to 2015. Results: Nearly 50% of the studies were supported by research funds. Most of the animal species in the studies were rats (81.1%) and mice (15.6%). The major animal models for human disease were cerebrovascular diseases (24.4%), skin problems (17.8%), and nerve injuries (15.5%). Immunohistochemistry (24.3%) was mainly used as an experimental technique. The main intervention and treatments used in the studies were chemical treatments, exercise and surgery. Conclusion: In this review, relevant results were described to identify the trends of nursing research using animal experimentation in Korea. Expansion of various nursing research using animal models can be required for gaining knowledge applicable to the same conditions in humans.

• Sleep Medicine and Psychophysiology
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• v.10 no.1
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• pp.5-11
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• 2003

Sleep apnea syndrome is a common clinical disorder characterized by intermittent cessation of airflow at nose and mouth during sleep. The clinical significance of this syndrome is that it is one of the most common causes of excessive daytime sleepiness. It can also cause neuropsychiatric, cardiovascular, and cerebrovascular complications. The standard for diagnosis of sleep apnea syndrome is nocturnal polysomnography. Because polysomnography is a time-consuming and expensive test, many efforts have been made to replace polysomnography with a simpler system of monitoring, but no method has yet been approved as a definitive investigation method. The goals of treatment for this syndrome are to eliminate excessive daytime sleepiness and to reduce the risk of possible cardiovascular complications. Continuous positive airway pressure is the most definite and widely accepted treatment for achieving these goals. Other treatments such as surgical treatment, oral appliances, and behavioral therapy may be useful for selected patients who are mildly affected.

• Physical Therapy Korea
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• v.3 no.2
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• pp.84-94
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• 1996

This paper reviews physiological changes in the nervous system of patients with hemiparesis that may contribute to muscle weakness. The discussion includes the important role that alterations in the physiology of motor units, notably changes in firing rates and muscle fiber atrophy, play in the manifestation of muscle weakeness. This role is compared with the lesser role that spasticity of the antagonist muscle group appears to play in determining the weakness of agonist muscles. The contribution of other factors that result in mechanical restraint of the agonist by the antagonist is discussed relative to muscle weakness in patients with hemiparesis. More studies on patients with hemiparesis are required to assess what role muscle strength training should play in rehabiliting patients after a stroke.

• Clinical and Experimental Pediatrics
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• v.58 no.6
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• pp.230-233
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• 2015

Lethargy in newborns usually indicates central nervous system dysfunction, and many conditions such as cerebrovascular events, infections, and metabolic diseases should be considered in the differential diagnosis. Nonketotic hyperglycinemia is an autosomal recessive error of glycine metabolism, characterized by myoclonic jerks, hypotonia, hiccups, apnea, and progressive lethargy that may progress to encephalopathy or even death. Cerebral sinovenous thrombosis is a rare condition with various clinical presentations such as seizures, cerebral edema, lethargy, and encephalopathy. Here, we report the case of a newborn infant who presented with progressive lethargy. An initial diagnosis of cerebral venous sinus thrombosis was followed by confirmation of the presence of nonketotic hyperglycinemia.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.2
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• pp.200-205
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• 2014

Based on the way we have created to measure the brain atrophy of pons, frontal lobe, sylvian fissure, ventricle, cerebellum, we analyzed the correlation with age. We confirmed whether the brain atrophy due to hypertension, diabetes, hyperlipidemia, drinking, smoking is increasing. Brain deficiency(髓海不足), Brain dissatisfied(腦爲之不滿), Brain Consume(腦髓消烁) listed in Donguibogam(東醫寶鑑) have to be diagnosed with brain atrophy induced by developmental disorders, diseases, aging. Sylvian fissure is well reflected brain atrophy progressed by aging. And brain atrophy increased in hypertension, diabetes, hyperlipidemia, drinking, smoking is well reflected at Sylvian fissure.

• Journal of Ginseng Research
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• v.35 no.4
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• pp.389-398
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• 2011

A total of 470 papers directly related to research on the Panax species were retrieved by performing internet searches with the keywords Panax and ginseng as the search terms. The publications were categorized as follows: 399 research articles, 30 reviews, 30 meeting abstracts, 7 proceedings, and 4 letters. The majority of these publications were published by scientists from Korea (35.7%), China (32.3%), and the USA (11.3%). Scientists from a total of 29 nations were actively involved in conducting ginseng research. A total of 43.6% of the publications were categorized as pharmacodynamic studies. The effects of ginseng on cerebrovascular function and cancer were the two most common topics considered in the pharmacodynamic studies. More than half of the ginseng studies assessed the use of P. ginseng. A total of 23 countries participated in studies specifically related to P. ginseng, and more than 80% of these studies originated from Korea and China. A total of 50 topics within the pharmacodynamics category were examined in association with the use of P. ginseng.

• Journal of Korean society of Dental Hygiene
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• v.16 no.2
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• pp.155-163
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• 2016

The purpose of the review article is to investigate the influence of periodontal diseases on preterm birth(PTB) and low birth weight(LBW). PTB and LBW are the main risk factors of infant mortality and a major public health problem. PTB is defined as delivery at less than 37 weeks and LBW is less than 2,500 grams. Over Approximately 60 percent of perinatal mortality results from PTB or LBW. Although the causes of PTB and LBW are not fully understood, infection is the leading cause of PTB and LBW. Periodontal diseases are serious disease burdens because they are caused by bacterial endotoxin, inflammatory reaction, and cytokine. The periodontal diseases are the predisposing factors of cerebrovascular and cardiovascular diseases including atherosclerosis. Over the past 15 years, previous studies revealed that periodontitis had adverse outcomes including PTB and LBW in pregnancy.

• Health Policy and Management
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• v.26 no.1
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• pp.1-3
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• 2016

The prevalence of non-communicable disease (NCD) has been continuously increasing due to population ageing, and the change in consumption and lifestyle patterns. Cancers, cerebrovascular diseases, and hypertensive diseases have been the major causes of deaths in the Republic of Korea since 1983. Numerous studies have suggested the need for a sustained comprehensive treatment tailored for individual patients and recommend the development of a systematic program to manage NCD patients to provide such care. It's necessary to develop the Korean model of the community based NCD prevention and control, consisting strategy of community movement, education for the NCD patients, and partnership the primary care clinic with public health organization to meet the needs in community people.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.5
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• pp.1339-1342
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• 2003

CVA is a kind of cerebrovascular disease which has a few local functional lesions of brain tissue, and it is generally caused by cerebral infarction, cerebral hemorrhage, and so on. It is also known as a stroke of paralysis, which leaves a lot of sequelae in a patient such as lesion of movement, perceiving, memory, sense, emotion, etc. A CVA patient which has a sequela, the sense disorder of equilibrium, took the Saam Acupuncture Therapy and Dr. Dong's Acupuncture Therapy, and then he was cured.

• Journal of Korean Society for Atmospheric Environment
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• v.24 no.5
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• pp.523-537
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• 2008

In Korea, the global warming leads to more frequent high temperature region. increasing the need for research into physical damage caused by high temperature. We therefore analyzed the differences of mortality, caused by extreme heat, among gender and age. We also examined the trend of mortality from high temperature-sensitive diseases. Women are more affected by exposure to high temperature than are men; People over 65 years old have higher mortality rate (1.5 times) than under 65. As for high temperature-related diseases, cerebrovascular disease was the number one cause of death, and chronic lower respiratory disease and cardiovascular disease followed.