• Title/Summary/Keyword: cerebrovascular

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Physiological approach of CADASIL animal model and its predictable implication (CADASIL 동물모델의 생리학적 접근 및 연구적 가치의 예측)

  • Jung, Sung-Cherl;Ko, Eun-A
    • Journal of Medicine and Life Science
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    • v.16 no.3
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    • pp.55-59
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    • 2019
  • Cerebral vessels are functionally and structurally specialized to provide adequate blood flow to brain which shows high metabolic rates. Cerebral hemorrhage or ischemic infarction due to cerebrovascular injury or occlusion can cause the immediate brain damage, and if not treated rapidly, can lead to serious or permanent brain damages, and sometimes life-threatening. Unlike these popular cerebrovascular diseases, there are diseases caused by genetic problems. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is one of them. CADASIL does not show the high incidence, but it is considered to be significantly affected by regional obstructiveness such as islands and therefore, to be an important genetic disease in Jeju. This paper aims to summarize the possibility of animal model research that can provide preclinical data for CADASIL disease research and to evaluate its applicability in future research plans.

Pilot Study on The Thermographic Change of Seven Acupoints by Digital Infrared Thermographic Imaging (적외선 체열 촬영을 이용한 중풍칠처혈 자침시 체표온도 변화에 관한 Pilot Study)

  • Lee, Yun-Kyu;Lee, Yoon-Kyoung;Seo, Bo-Myung;Yun, Jong-Seok;Kim, Kyung-Un;Choi, Sung-Hun;Lee, Kyung-Min;Lim, Seong-Chul;Jung, Tae-Young;Han, Sang-Won;Seo, Jung-Chul
    • Journal of Pharmacopuncture
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    • v.8 no.3
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    • pp.115-121
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    • 2005
  • Objectives : This study was designed to find out the effect of seven acupoints of stroke in cerebrovascular hemiplegia patients. Methods : This study was performed on 6 patients with cerebrovascular hemiplegia (test group) and 6 health persons(control group). We measured temperature of skin surface of test and control group using digital infrared thermographic imaging(D.I.T.I) after acupunture on seven acupoints of stroke. And we calculated difference of skin temperature between healthful and affected side for each groups. Results : There was significant difference in area 3 in both two groups between before and after acupuncture. But in general there Was no significant difference between two groups on thermographic change. Conclusions : This is pilot study, so further studies are required to find out the effect of seven acupoints of stroke in cerebrovascular hemiplegia patients.

A Review of Dementia in Korean Medicine during the last ten years (최근 10년간 치매에 대한 한의학적 연구 동향 고찰)

  • Ryu, Ki-Jun;Kim, Ji-Hyung;An, Keon-Sang;Lee, Je-Kyun;Kwon, Seung-Ro
    • Journal of Oriental Neuropsychiatry
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    • v.18 no.3
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    • pp.135-145
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    • 2007
  • Objective: The purpose of this study is to indicate further research direction in dementia by examining recent Korean-medicine journals. Method: We have reviewed eleven different journals that have been published from 1997 to 2006. Result 1.In philological study paper, cerebrovascular dementia is most common type of dementia and age, sex, past history have influence on the attack of disease. Introduced medical treatment to dementia of Korean medicine are Removing wind(祛風), Be in the peace(安神), Refreshing lung and raising blood(淸肺養血) etc. 2.According to the research paper, a prognosis of dementia which Is mixed(Alzheimer type and cerebrovascular type) is bad. Sinmac(申脈)-BL.62), Jeohae(照海)-Kl.06), waegwan(外關)-TE.05), naegwan(內關)-PC.6) among the palmacgyohoeheol(八脈交會穴) have good effect in medical treatment. Medical treatment which is based on chaejil(體質)) shows up to be more effective. Also many medicines have good effect, especially chongmyung-tang(聰明湯)) and chongmyung-tang-gamibang(聰明湯加味方)) have good effect on decreasing memory caused by nerve cell degeneration. Conclusion: The Korean medical treatments have many advantage in taking the dementia so the researches about this are more needed.

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Effects of a Comprehensive Lifestyle Improvement Program for Middle-aged Women with Cardio-cerebrovascular Disease-related Risk Factors (심뇌혈관질환 위험요인을 가진 중년여성을 위한 통합적 생활습관개선 프로그램의 효과)

  • Park, Mi-Kyoung;Kim, Jeong-Hee
    • Research in Community and Public Health Nursing
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    • v.24 no.2
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    • pp.111-122
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    • 2013
  • Purpose: This study was conducted to evaluate effects of a comprehensive lifestyle improvement program for middle-aged women with cardio-cerebrovascular disease (CVD)-related risk factors. Methods: The research adopted a non-equivalent control group pretest-posttest design. The number of participants was 18 in the experimental group and 16 in the control group sampled among middle-aged women who had CVD-related risk factors residing in a community. The experimental group participated in a four-session comprehensive lifestyle promotion program, which consisted of lectures, demonstrations, small-group meetings and telephone-counseling. The effects of the program were evaluated by measuring knowledge, attitude, health behavior, and self-efficacy for CVD prevention. Results: The experimental group showed a significant increase in self-efficacy for CVD prevention compared to the control group. There was no significant increase in knowledge, attitude, and health behavior. Conclusion: The results suggest that the comprehensive lifestyle improvement program was effective in improving self-efficacy for CVD prevention. There is a need to develop more effective lifestyle improvement programs designed to improve knowledge, attitude, and health behavior for CVD prevention. In further research, a follow-up evaluation is also needed to investigate any delayed effects on targeted variables among which no significant differences emerged immediately after the completion of the program.

Public Perception of the Concentration of Cardiac and Cerebrovascular Surgery to Metropolitan Hospitals

  • Lee, Young-Hoon;Lee, Kun Sei;Jeong, Hyo Seon;Ahn, Hye Mi;Oh, Gyung-Jae
    • Journal of Chest Surgery
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    • v.49 no.sup1
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    • pp.44-52
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    • 2016
  • Background: This study investigates the perception of the general public regarding the concentration to metropolitan, hospitals of cardiac and cerebrovascular surgeries, and the perceived public need for government policies to resolve this issue. Methods: A total of 800 participants were recruited for our telephone interview survey. Quota sampling was performed, adjusting for age and sex, to select by various geographic regions. Sampling with random digit dialing was performed; we called the randomly generated telephone numbers and made three attempts for non-responders before moving on to a different telephone number. Results: Our sample population was 818 participants, 401 men (49.0%) and 417 women (51.0%). Our data showed that 85.5% of participants thought that cardiac surgery and neurosurgery patients are concentrated in large hospitals in Seoul. The principle reason for regional patients to want to receive surgery at major hospitals in Seoul was because of poor medical standards associated with regional hospitals (87.7%). We found that a vast majority of participants (97.5%) felt that government policies are needed to even out the clustering of cardiac surgery and neurosurgery patients, and that this clustering may be alleviated if policies that can specifically enhance the quality and the capacity of regional hospitals to carry out surgeries are adopted (98.3%). Conclusion: Government policy making must reflect public desiderata, and we suggest that these public health needs may be partially resolved through government-designated cardiac and neurosurgery specialist hospitals in regional areas.

Surgical Management of Pseudoaneurysm (가성동맥류의 수술적 가료)

  • Kim, Jae Hong;Yim, Man Bin;Lee, Chang Young;Kim, Ill Man
    • Journal of Korean Neurosurgical Society
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    • v.30 no.3
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    • pp.307-318
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    • 2001
  • Objective : Surgical experiences of pseudoaneurysms such as traumatic, mycotic and ill-defined unknown causes of aneurysms are rare. The authors have studied the results of surgical management from such cases in our series. Patients and Method : In the last 17 years, 1320 patients with cerebrovascular aneurysms were managed surgically. Among these, 16 patients showed the pseudoaneurysms. The authors analyzed retrospectively the clinical characteristics, treatment methods, management outcomes and problems in the managements. Results : There were 6 patients with traumatic aneurysm, 4 mycotic aneurysms and 6 ill-defined unknown causes of aneurysm. The sites of traumatic aneurysms were cavernous portion of the internal carotid artery(n=3), distal portion of the anterior cerebral artery (n=2) and vertebral artery(VA : n=1). Good outcomes in 5 cases could be obtained by extracranial - intracranial bypass followed by parent vessel occlusion or resection of aneurysm followed by re-anastomosis of parent vessel. The sites of mycotic aneurysm were peripheral portions of middle cerebral artery(MCA : n=3) and posterior cerebral artery(PCA : n=1). The outcomes of the patients with a mycotic aneurysm were relatively poor. It was partially due to the development of new aneurysm after treatment in one. The sites of ill-defined unknown causes of aneurysm were extracranial carotid artery(n=3), V2 portion of the VA(n=1), peripheral portion of the PCA (n=1) and MCA(n=1). Good outcome in all cases could be obtained by resection of aneurysm with or without saphenous vein graft. Conclusion : For the treatments of cerebrovascular pseudoaneurysm, combinations of aggressive medical, endovascular and surgical managements seem mandatory. Insertion of stent for a extracranial carotid artery aneurysm and coiling for a peripheral mycotic aneurysm can be option in future.

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