• 대한미생물학회지
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• 제3권1호
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• pp.15-23
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• 1968

For the effective control of Syphilis, many investigators have developed a more rapid, simple and economical screening serological test which is adequately sensitive and specific. To fulfill the requirements of a more rapid serologic test for syphlis, a substitute for the conventional serum specimen was needed since considerable time and labor are involved in the processing of blood to serum. Burdon suggested the use of plasma in the serologic tests for syphilis as a substitute for serum. He noticed that plasma was more sensitive than serum in the Kline and Kahn tests, and attributed this to the presence of more antibody-like substance, "reagin" in plasma than in serum. However, to make plasma sufficiently sensitive, it was necessary to inactivate plasma by heating at a temperature of $56^{\circ}C$ for about 30 minutes. Heating of plasma resulted in the precipitation of fibrinogen which made centrifugation necessary to obtain dear plasma. Since the chief disadvantage to the use of unheated plasma(or serum) was a reduction in sensitivity of results-which probably was due to a labile factor such as complement-Portnoy et al began to consider rapid chemical methods of inactivation of plasma(or serum). They experienced that choline chloirde was shown to be anticomplementary which suggested its use as an inactivating agent for unheated plasma(or serum). In 1959 Portnoy et al reported the Rapid Plasma Reagin(RPR) Test for syphilis which is a more rapid, economical and simple. But still this test has many disadvantages as a rapid performing, field and office procedure, because it requires the usual laboratory equipments such as centrifuge, rotating machine, microscope etc. To substitute these disadvantages of the RPR test, in 1962, Portnoy et al developed the Rapid Plasma Reagin(RPR) card test for syphilis, which has the following advantages: a) Simplicity and rapidity of performance, b) Requires no laboratory equipments, c) Stable antigen suspension, d) Adequate sensitivity and specificity. This RPR card test can be used as a rapidly performing and screening test in field investigation, outpatient clinics, small laboratories and hospitals doing limited syphilis serology, and predonor in blood bank. Private clinic which has limited laboratory equipment and technic for syphilis serology can also use this RPR card test as a tool in the rapid diagnosis of syphilis. It was thought that this RPR card test is a useful tool in Korea for private physician and mass survey for syphilis diagnosis. But Portnoy patented the reagents needed for the performing the RPR card test. Therefore authors developed newly the reagents and according to Portnoy's method evaluated the newly developed. RPR card test compared with the VDRL, Kolmer CF, and RPCF tests. The RPR card and VDRL tests were performed plasma and serum from the total 1,132 cases. Among these 1,131 cases, 521 were syphilis suspected laboratory specimens, and 611 were syphilis unsuspected healthy young men. After screening with these two tests, the RPR card and VDRL tests, reactive specimens to the above one or both tests were retested by the Kolmer CF and RPCF tests.

• 한국지반환경공학회 논문집
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• 제13권12호
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• pp.67-74
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• 2012

기존건물의 지하층과 인접하여 굴착 시 양단벽체 토사의 마찰로 발생하는 아칭효과는 굴착벽체에 작용하는 토압을 경감시키게 된다. 본 논문에서는 굴착깊이에 대한 배면폭의 비와 벽마찰각의 변화에 따른 아칭효과의 변화를 다양한 조건에서 수치해석을 통하여 살펴보았다. 수치해석 모델은 원심모형시험결과를 바탕으로 검증하여 적용하였으며, 아칭에 의한 토압경감 효과는 굴착깊이에 대한 배면폭의 비가 작고 벽마찰각이 커짐에 따라 증가함을 알 수 있었다. 이와 같은 아칭 현상은 기존의 아칭이론 중 Handy(1985)가 제안한 이론식을 통하여 가장 정확히 묘사 가능함을 알 수 있었다.

• Geomechanics and Engineering
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• 제21권5호
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• pp.489-501
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• 2020

This paper conducts a complicated coupled effective stress analysis of X-section-in-place concrete (XCC) pile installation and consolidation processes using the dual-stage Eulerian-Lagrangian (DSEL) technique incorporating the modified Cam-clay model. The numerical model is verified by centrifuge data and field test results. The main objective of this study is to investigate the shape effect of XCC pile cross-section on radial total stress, excess pore pressure and time-dependent strength. The discrepancies of the penetration mechanism and set-up effects on pile shaft resistance between the XCC pile and circular pile are discussed. Particular attention is placed on the time-dependent strength around the XCC pile shaft. The results show that soil strength improved more significantly close to the flat side compared with the concave side. Additionally, the computed ultimate shaft resistance of XCC pile incorporating set-up effects is 1.45 times that of the circular pile. The present findings are likely helpful in facilitating the incorporation of set-up effects into XCC pile design practices.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 1999년도 가을 학술발표회 논문집
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• pp.161-168
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• 1999

A series of centrifuge model tests were performed in order to investigate the behaviors of various tunnel linings. A 1/100-scaled aluminum and hydrostone horseshoe tunnel linings with a radius km, height km were buried in a depth of C/D=3 with dry Joomunjin standard sand, the relative density of which was 86%. Bending moments and thrusts along the tunnel circumference were measured by 12 strain gages. Earth pressures in soil and on lining were estimated by pressure transducers, ground surface settlements at center and edges by using LVDTs. Average Ko(coefficient of earth pressure at rest) was 0.39 for the model sand. The structural behaviors of lining depended on its damaged conditions. But, as a rule, on the crown, the tensile circumferential strain of lining occurred at the inner surface, and the compressive at the outer surface, then positive bending moment was created at the crown. The circumferential strain of the inner surface on the springline was tensile, and the outer compressive, so negative bending moment was measured at the springline. For hydrostone linings, cracks initiated at the inner surface on the crown, and the outer on the springline over average 40g.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2010년도 추계 학술발표회
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• pp.201-204
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• 2010

Earthquake load to design a structure has been calculated from a fixed base SDOF model using amplified surface accelerations along soft soil layers. But the method dose not consider a soil-structure interaction. Centrifugal experiments that were consisted of soil, a shallow foundation and a structure were performed to find the effects of soil-structure interaction. The experiments showed that mass and stiffness of the foundation affected a response of the structure and nonlinear behavior of soil near the foundation. And a rocking displacement caused by overturning moment affected the response and increases a damping effect. In this study, the centrifugal experiment was simulated as a two dimensional finite element model. The finite element model was used for nonlinear time domain analysis of the OpenSees program. The numerical model accurately evaluated the behaviors of soil and the foundation, but the rocking effect and the behavior of structure were not described.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2004년도 춘계학술발표회
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• pp.738-745
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• 2004

There are a number of ways to reduce the ground vibrations, one of which is by installing underground walls. Model tests for ground vibration have been conducted in recent years, but limited attention has been paid to underground wall which can reduce high vibrations. Up to date, only barriers have been actually installed in dry sand because of many unknown factors subsisting on the behavior of the ground. The characteristics of vibration sources, ground conditions and wall barriers have not been well understood yet, therefore centrifugal modeling was adopted to examine all these characteristics. This paper describes a ball dropping system, which can generate a pulse wave propagation through soil mass, and the test results show the effectiveness of underground wall barrier in reducing mechanical vibration.

• 산업기술연구
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• 제25권A호
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• pp.57-65
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• 2005

In this paper, for the highly plastic marine soft clay distributed in west and southern coast of Korean peninsula of Kwangyang and Busan New Port areas, correlation between compression index and other indices representing geotechnical engineering properties such as liquid limit, void ratio and natural water content were analyzed. Appropriate empirical equations of being able to estimate the compressibility of clays in the specific areas were proposed and compared with other existing empirical ones. For analyses of the data and test results, data for marine clays were used from areas of the South Container Port of the Busan New Port, East Breakwater, Passenger Quay, Jungma Reclamation and Reclamation Containment in the 3rd stage in Kwangyang. In order to find the best regression model by using the commercially available software, MS EXCEL 2000, results obtained from the simple linear regression analysis, using the values of liquid limit, initial void ratio and natural water content as independent variables, were compared with the existing empirical equations. Multiple linear regression was also performed to find the best fit regression curves for compression index and other soil properties by combining those independent variables. On the other hands, another software of SPSS for non-linear regression was used to analyze the correlations between compression index and other soil properties.

• Geomechanics and Engineering
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• 제21권1호
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• pp.73-84
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• 2020

In the seismic design of bridges, formation of plastic hinges plays an important role in the dissipation of seismic energy. In the case of conventional fixed-base bridges, the plastic hinges are allowed to form in the superstructure alone. During seismic event, such bridges may be safe from collapse but the superstructure undergoes significant plastic deformations. As an alternative design approach, the plastic hinges are guided to form in the soil thereby utilizing the inevitable yielding of the soil. Rocking foundations work on this concept. The formation of plastic hinges in the soil reduces the load and displacement demands on the superstructure. This study aims at evaluating the seismic response of bridge pier supported on rocking shallow foundation. For this purpose, a BNWF model is implemented in OpenSees platform. The capability of the BNWF model to capture the SSI effects, nonlinear behavior and dynamic loading response are validated using the centrifuge and shake table test results. A comparative study is performed between the seismic response of the bridge pier supported on the rocking shallow foundation and conventional fixed-base foundation. Results of the study have established the beneficial effects of using the rocking shallow foundation for the seismic response analysis of the bridge piers.

• 한국지반공학회논문집
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• 제16권5호
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• pp.179-191
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• 2000

본 연구에서는 화강토 지반상의 자립식 diaphragm wall의 거동을 연구하기 위하여 벽체의 근입깊이비, 지하수위 및 굴착조건(연속 및 단계굴착)을 변화시키면서 원심모형시럼을 수행하였다. 원심모형실험시 지반굴착은 흙과 동일한 밀도로 혼합된 zine chloride 용액이 배수되도록 밸브를 조작하여 실시하였으며, 굴착에 의해 발생되는 지반의 변형괴 벽체의 변위 및 휨모멘트를 시간경과에 따라 측정하였다. 실험결과, 벽체의 근입깊이비가 증가함에 따라 벽체의 휨모멘트는 증가하는 반면, 굴착과정동안 배면측에서의 간극수압 감소속도는 감소하였다. 최종 굴착단계에서 굴착후 시간경과에 따른 침하량은 굴착과정중의 침하？에 비해 5~7% 정도를 나타내었다. 최대표면침하량과 벽체변위를 굴착깊이로 정규화한 결과 최대 침하량은 벽체 변위량의 0.8~1.2배9평균0.91배)사이에 분포하였다. 굴착깊이로 전규화한 벽체변위와 근입깊이와의 관계는 지수함수식으로 제안하였다. 파괴면은 직선적인 형태로 파괴면내의 배면측 지반은 벽체를 향하여 하향의 변위를 일으키면서 벽체의 회전에 의해 파괴되었으며, 퐈괴면의 각도는 66~72.5$^{\circ}$정도로 이론적인 파괴면의 각도보다 크게 평가되었다.

• Geomechanics and Engineering
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• 제11권6호
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• pp.847-865
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• 2016

In this study, a series of geotechnical centrifugal tests were conducted to investigate the effectiveness of settlement control of two types of rigid pile structure embankments (PRSE) in collapsible loess under high-speed railway embankments. The research results show that ground reinforcement is required to reduce the post-construction settlement and settlement rate of the embankments. The rigid pile structure embankments using rigid piles can substantially reduce the embankment settlement in the construction of embankments on collapsible loess, and the efficiency in settlement reduction is affected by the pile spacing. The pile-raft structure embankments (PRSE) have much stronger ability in terms of the effectiveness of settlement control, while the pile-geogrid structure embankments (PGSE) provides rapid construction as well as economic benefits. Rational range of pile spacing of PRSE and PGSE are suggested based on the requirements of various railways design speeds. Furthermore, the time effectiveness of negative skin friction of piles and the action of pile-cap setting are also investigated. The relevant measures for improving the bearing capacity and two parts of transition zone forms as positive control mean have been suggested.