• Title/Summary/Keyword: central depression

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The Impacts of Childhood Trauma on Psychosocial Features in a Chinese Sample of Young Adults

  • Wang, Dandan;Lu, Shaojia;Gao, Weijia;Wei, Zhaoguo;Duan, Jinfeng;Hu, Shaohua;Huang, Manli;Xu, Yi;Li, Lingjiang
    • Psychiatry investigation
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    • v.15 no.11
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    • pp.1046-1052
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    • 2018
  • Objective The aims of the present study were to explore the occurrence of childhood trauma and importantly to determine the impacts of childhood trauma on psychosocial features in a Chinese sample of young adults. Methods A survey was carried out in a group of 555 university students by using Childhood Trauma Questionnaire (CTQ), Self-rating Depression Scale (SDS), Self-rating Anxiety Scale (SAS), Dysfunctional Attitudes Questionnaire (DAS), Eysenck Personality Questionnaire (EPQ), and Social Support Rating Scale (SSRS). The moderate-severe cut-off scores for CTQ were used to calculate the prevalence of childhood trauma, and then psychosocial features were compared between individuals with and without childhood trauma. Results A proportion of 18.6% of university students had self-reported childhood trauma exposures. Subjects with childhood trauma reported higher scores of SDS, SAS, DAS, and psychoticism and neuroticism dimensions of EPQ (t=4.311-5.551, p<0.001); while lower scores of SSRS and extraversion dimension of EPQ (t=-4.061- -3.039, p<0.01). Regression analyses further revealed that scores of SAS and DAS were positively (Adjusted B=0.211-0.230, p<0.05), while scores of SSRS were negatively (Adjusted B=-0.273- -0.240, p<0.05) associated with specific CTQ scores. Conclusion Childhood trauma is still a common social and psychological problem. Individuals with childhood trauma show much more depression, anxiety, distorted cognition, personality deficits, and lower levels of social support, which may represent the social and psychological vulnerability for developing psychiatric disorders after childhood trauma experiences.

A Study on the Behavior of Body Piercing According to Body Piercer's Feeling of Depression to a Sex Role Identity, Self-Conception and Self-Strength (Body Piercer의 성역할 정체감, 자아개념, 자아강도에 따른 신체장식행동에 관한 연구)

  • Yoon, Kyoung-Bin;Yoo, Tai-Soon
    • Fashion & Textile Research Journal
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    • v.8 no.5
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    • pp.537-544
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    • 2006
  • The purpose of this study is as well as Body decoration is a means to identify self-expression from the original nature of an individual freedom and originality, so there remains a race has not a cloth on, but there is no race does not pierce, it has been done with the beginning of a mankind. Subjects for this study were 202 persons, who experienced body piercing with twenties as the central figure. Statistical analysis was done by using SPSS 10.0 version and included AVOVA, Cronbach ${\alpha}$ realbility, Multiple Regression Analysis, Duncan's multiple range test, and Cross tabulation analysis. The result are as follow, The difference of self-conception classified by body piercer's sex distinction did not show significantly. Of the body piercer's feeling of depression to a sex role, neuter gender's feeling of depression showed highly in case of the physical self and the moral self and in case of the social self neuter's feeling and feminine gender's feeling to a sex role showed high. For the reason why he/she did body piercing, neuter gender's feeling showed high in case of influenced by the fashion and masculine gender's and feminine gender's feeling showed high in case of influenced by the curiosity. The body decoration classified by self-conception of body piercer did not show a significant difference.

Effects of Herbal Medicine (Gan Mai Da Zao Decoction) on Several Types of Neuropsychiatric Disorders in an Animal Model: A Systematic Review - Herbal medicine for animal studies of neuropsychiatric diseases -

  • Kim, Su Ran;Lee, Hye Won;Jun, Ji Hee;Ko, Byoung-Seob
    • Journal of Pharmacopuncture
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    • v.20 no.1
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    • pp.5-9
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    • 2017
  • Objectives: Gan Mai Da Zao (GMDZ) decoction is widely used for the treatment of various diseases of the internal organ and of the central nervous system. The aim of this study is to investigate the effects of GMDZ decoction on neuropsychiatric disorders in an animal model. Methods: We searched seven databases for randomized animal studies published until April 2015: Pubmed, four Korean databases (DBpia, Oriental Medicine Advanced Searching Integrated System, Korean Studies Information Service System, and Research Information Sharing Service), and one Chinese database (China National Knowledge Infrastructure). The randomized animal studies were included if the effects of GMDZ decoction were tested on neuropsychiatric disorders. All articles were read in full and extracted predefined criteria by two independent reviewers. Results: From a total of 258 hits, six randomized controlled animal studies were included. Five studies used a Sprague Dawley rat model for acute psychological stress, post-traumatic stress disorders, and unpredictable mild stress depression whereas one study used a Kunming mouse model for prenatal depression. The results of the studies showed that GMDZ decoction improved the related outcomes. Conclusion: Regardless of the dose and concentration used, GMDZ decoction significantly improved neuropsychiatric disease-related outcomes in animal models. However, additional systematic and extensive studies should be conducted to establish a strong conclusion.

Effect of Autogenic Training for Stress Response: A Systematic Review and Meta-Analysis (아우토겐 트레이닝이 스트레스반응에 미치는 효과: 체계적 문헌고찰 및 메타분석)

  • Seo, Eunju;Kim, Soukyoung
    • Journal of Korean Academy of Nursing
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    • v.49 no.4
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    • pp.361-374
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    • 2019
  • Purpose: This study was conducted to evaluate the effectiveness of autogenic training on stress responses through a systematic review and meta-analysis. Methods: A systematic search was conducted using eight core electronic databases (Embase, CENTRAL, Medline, CINAHL, PsycInfo, DBpia, KISS, and RISS). To estimate the effect size, a meta-analysis of the studies was performed using RevMan 5.3.5 program. Results: A total 21 studies out of 950 studies were included in the review, and 11 were included for meta-analysis. These studies showed that autogenic training decreased anxiety and depression, and increased the high frequency of heart rate variability. Calculations to understand the effect of autogenic training on anxiety, through a meta-analysis, observed a reduction effect of anxiety score by 1.37 points (n=85, SMD=-1.37: 95% CI -2.07 to -0.67), in the studies on short-term intervention targeting healthy adults. On the other hand, similar calculations to understand the effect of autogenic training on depression observed, a reduction effect on the depression score by 0.29 point (n=327, SMD=-0.29: 95% CI -0.50 to -0.07), in the studies on long term intervention targeting the patient group. Conclusion: Autogenic training is effective for adults' stress management, and nurses will be able to effectively perform autogenic training programs for workers' stress relief at the workplace.

Cognitive Impairment in the Patients with Mildly Active Systemic Lupus Erythematosus (경증 전신성 홍반성 루프스 환자의 인지기능장애)

  • Kim, Jin-Hee;Lee, Chul;Lee, Chang-Uk;Paik, In-Ho
    • Korean Journal of Psychosomatic Medicine
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    • v.5 no.1
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    • pp.89-96
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    • 1997
  • This study was designed to determine whether cognitive impairment was evident in patients with SLE. Also, it aimed to examine the association of cognitive impairment with other clinical variables. The subjects consisted of 20 patients with mildly active SLE and 20 healthy controls. Methods : A total of 20 SLE patients and 20 normal controls completed a computerized neuropsychological test battery using Vienna Test System. These included Cognitrone test, Continuous attention test, Corsi block tapping test, Standard progressive matrices. Also, neuro-behavioral cognitive status examination was done. The symptom severity of depression was measured with Beck Depression Inventory, Hamilton Depression Rating Scale, and current medications were documented. Disease activity was rated using the SLE diasease activity index (SLEDAI). Results : SLE patients had poorer performance than normal controls on the tests of Cognitrone, attention, nonverbal IQ and memory, independent of age, education, disease activity, steroid use and depression status. Conclusion : Cognitive dysfunction was not uncommon in ambulatory SLE patients as measured by standardized neuropsychological tests. It seemed to occur independently of various clinical variables. These findings would suggest that cognitive dysfunction in SLE may be explained by reflecting subclinical central nervous system(CNS) involvement, rather than coexisting psychological distress due to chronic illness or side effect of medication.

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Associations of serum 25(OH)D levels with depression and depressed condition in Korean adults: results from KNHANES 2008-2010 (한국 성인의 혈청 25(OH)D 수준과 우울증 및 우울증상 경험과의 연관성: 국민건강영양조사 2008-2010 분석 결과)

  • Koo, Sle;Park, Kyong
    • Journal of Nutrition and Health
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    • v.47 no.2
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    • pp.113-123
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    • 2014
  • Purpose: Vitamin D has been known to play an important role in the central nervous system and brain functions in the human body, and cumulative evidence has shown that vitamin D deficiency might be linked with various mental health conditions. Epidemiologic studies have shown that vitamin D deficiency may be associated with higher risk of depression in the US and European populations. However, limited information is available regarding the association between vitamin D status and depression in the Korean population. The objective of this study was to examine the associations between vitamin D levels and prevalence of depression. Methods: We conducted a cross-sectional analysis using nationally representative data from the 2008-2010 Korean National Health and Nutrition Examination Survey from which serum 25-hydroxyvitamin D concentrations were available. A total of 18,735 adults who had available demographic, dietary, and lifestyle information were included in our analysis. We defined "depression" with a diagnosis by a physician. "Depressed condition" was defined as having feelings of sadness or depression without diagnosis by a physician. Results: The prevalence of depression was 1.63% and 5.43% in Korean men and women, respectively; 12.5% of men and 26.1% of women were defined as the group having depressed conditions. In multivariate logistic regression models, no significant associations were observed between vitamin D status and prevalence of depression or depressed conditions in Korean men and women. Conclusion: We found no association between vitamin D insufficiency and depression/depressed conditions in Korean adults. Future large prospective studies and randomized controlled trials are needed to confirm this relationship.

Preliminary Study on a Microsporidian Isolate Occurring in the Lamerin Breed of the Silkworm Bombyx mori L. in India

  • Bhat, Shabir Ahmad;Nataraju, B.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.9 no.2
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    • pp.265-267
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    • 2004
  • The silkworm, Bombyx mori L. is prone to infection of various pathogenic organisms. Pebrine, one of the deadliest disease of silkworm caused by highly virulent parasitic microsporidian, Nosema bombycis has been understood since long. Infections of the disease range from chronic to highly virulent and can result in complete lose to the sericulture industry. Several strains and species of microsporidians have since been isolated from the infected silkworms. A new microsporidian spore was isolated from Lamerin breed of the silkworm B. mori have been studied under scanning electron microscope, found to be different in spore size (length 4.36$\pm$0.06 ${\mu}{\textrm}{m}$, width 2.14$\pm$0.01${\mu}{\textrm}{m}$) and shape (ova cylindrical with slight depression) from standard strain N. bombycis (length 3.08$\pm$0.21 ${\mu}{\textrm}{m}$, width 2.01$\pm$0.05 ${\mu}{\textrm}{m}$ and ovidal respectively). In immunological test, the silkworm breed Lamerin isolated micrisporidian spore does not react to different antibody (N. bombycis, M$_{11}$ and M$_{12}$) sensitized latex particle and thus appeared to be a different strain of microsporidian parasitic to the Lamerin breed of the silkworm B. mori.i.i.

A Synaptic Model for Pain: Long-Term Potentiation in the Anterior Cingulate Cortex

  • Zhuo, Min
    • Molecules and Cells
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    • v.23 no.3
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    • pp.259-271
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    • 2007
  • Investigation of molecular and cellular mechanisms of synaptic plasticity is the major focus of many neuroscientists. There are two major reasons for searching new genes and molecules contributing to central plasticity: first, it provides basic neural mechanism for learning and memory, a key function of the brain; second, it provides new targets for treating brain-related disease. Long-term potentiation (LTP), mostly intensely studies in the hippocampus and amygdala, is proposed to be a cellular model for learning and memory. Although it remains difficult to understand the roles of LTP in hippocampus-related memory, a role of LTP in fear, a simplified form of memory, has been established. Here, I will review recent cellular studies of LTP in the anterior cingulate cortex (ACC) and then compare studies in vivo and in vitro LTP by genetic/pharmacological approaches. I propose that ACC LTP may serve as a cellular model for studying central sensitization that related to chronic pain, as well as pain-related cognitive emotional disorders. Understanding signaling pathways related to ACC LTP may help us to identify novel drug target for various mental disorders.

Diagnostic considerations in central odontogenic fibroma of the maxilla: 2 case reports

  • Seo, Yu-Kyeong;Kang, Ju Hee;Lee, Sae Rom;Choi, Yong-Suk;Hwang, Eui-Hwan;Oh, Song Hee
    • Imaging Science in Dentistry
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    • v.49 no.3
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    • pp.229-234
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    • 2019
  • Central odontogenic fibroma (COF) is defined as a fibroblastic odontogenic tumor characterized by varying density of the tooth epithelium. It is an extremely rare benign neoplasm that occurs in the maxilla and the mandible; only a few reports of COF are available in the literature. Diagnosis of the lesion based only on the radiological features of COF is difficult due to variation in the findings regarding this condition. This report describes 2 clinical cases of middle-aged women with COF. Clinical examination revealed palatal mucosal depression; additionally, oral examination, as well as panoramic radiographs, intraoral radiographs, and computed tomography scans, revealed severe root resorption. This report highlights the clinical and radiological imaging features of COF, with the goal of enabling straightforward differential diagnosis of the lesion by the clinician and thereby appropriate treatment of the patient.

Volcanisms and Volcanic Processes of the Wondong Caldera, Korea (원동 칼데라의 화산작용과 화산과정)

  • 황상구;이기동;김상욱;이재영;이윤종
    • The Journal of the Petrological Society of Korea
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    • v.6 no.2
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    • pp.96-110
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    • 1997
  • The Wondong Caldera, formed by the voluminous eruption of the rhyolitic ashflows of the Wondong Tuff which is about 1,550 m thick at the intracaldera and 550 m at the outflow, is a resurgent caldera which shows a dome structure on the central exposure of the caldera. The Wondong caldera volcanism eviscerated the magma chamber by a series of explosive eruptions during which rhyolitic magma was ejected, as small fallouts and voluminous ash-flows, to form the Wondong Tuff. The explosive eruptions began with ash-falls, progressed through pumice-falls and transmitted ash-flows. During the ash-flow phase the initial central vent eruption transmitted into late ring-fissure eruption which accompanied with caldera collapse. Contemporaneous collapse of the roop of the chamber resulted in the formation of the Wondong Caldera, a subcircular depression subsiding about 1,930 deep. Following the collapse, quartz porphyry was intruded as ring dykes along the ring fracture near the southwestern caldera rim. Subsequently the central part of the caldera floor began to be uplifted into a circular resurgent dome by the rising of residual magma. Concurrent with the resurgent doming, the volcaniclastic sediments of Hwajeri Formation were accumulated in the caldera moat and then rhyodacite lava erupted from the initial central resurgent dome and another ash-flow tuff from the northern ring fracture. After the sedimentation, the find-grained granodiorite was intruded as an arc along the eastern ring fracture of the caldera. Finally in the central part, the resurgent magma was emplaced as a hornblende biotite granite stock that formed the central dome.

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