• Korean Journal of Acupuncture
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• v.19 no.1
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• pp.1-6
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• 2002

It was proposed that the substance of Kyungrak is a new anatomic-histological system in the living body and entirely different either from the nervous system or blood and lyphatic vessels. This system is covering the whole body, regulating and coordinating the biological processes that lie at the bottom of the vital activity. One of the substance of Kyungrak is acublast. The aim of this study was to isolate and culture the acublast from human placenta or blood of umbilical cord. It was found that particular cell organism isolate from placenta and cultured with RPMI 1640 contaning 10% FBS and hormones was grown for four weeks. Although this organism was different from blood cells morphologically, biochemical study of the organism is required to identify as the acublast.

• Proceedings of the SCSK Conference
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• 2003.09a
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• pp.320-326
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• 2003

Recently several studies have indicated that ubiquinone-l0 (CoQ-10) decrease with aging in various organs of the human body. The decrease of ubiquinone-10 in the aging process suggests the reduction of both energy production in mitochondria and anti-oxidation with aging. Based on these findings, Ubiquinone-10 is being focused at as an anti-aging agent in the cosmetic market.(omitted)

• Biomedical Science Letters
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• v.16 no.3
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• pp.179-185
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• 2010

Benzene is known as a ubiquitous air pollutant and has a carcinogenic influence on the human body. Benzene is also metabolized to other volatile organic compounds (VOCs) in the body such as phenol and hydroquinone (HQ). The metabolites are accumulated and further oxidized by myeloperoxidase in bone marrow. They act as toxic agents and cause a variety of diseases, including cancer, atopic dermatitis and asthma. In this study, we examined the effects of benzene and its metabolites on proliferation, differentiation and chemotaxis of EoL-1 cells, the human eosinophilic leukemia cell line. These chemicals had no effect on the proliferation of EoL-1 cells. Benzene decreased the differentiation of EoL-1 cells induced by butyric acid. HQ was induced the cell death during butyric acid-induced EoL-1 cell differentiation. In a chemotaxis experiment, benzene, phenol and HQ enhanced the cell migration induced by Lkn-1 but not by MCP-1, eotaxin, MIP-$1{\alpha}$ and RANTES. These findings provide the effect of VOCs on the regulation of eosinophil-involved immune response.

• Food Science and Biotechnology
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• v.17 no.6
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• pp.1214-1220
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• 2008

Secondary metabolites from the fruit body of Phellinus linteus were evaluated for their proliferative effect on human osteoblast-like cells. 3-[4,5-Dimethylthiazole-2-y1]-2,5-diphenyl-tetraxolium bromide (MTT) assay and alkaline phosphatase (ALP) activity assay were used to assess the effect those isolates on the human osteoblast-like cell line (Saos-2). Activity-guided fractionation led to the isolation of ALP-activating phenolic compounds through the extraction of P. linteus, solvent partitioning, and repeated silica gel and octadecyl silica gel (ODS) column chromatographic separations. From the result of spectroscopic data including nuclear magnetic resonance (NMR), mass spectrometry (MS), and infrared spectroscopy (IR), the chemical structures of the compounds were determined as 4-(4-hydroxyphenyl)-3-buten-2-one(1), 2-(3',4'-dihydroxyphenyl)-1,3-benzodioxole-5-aldehyde (2), 4-(3,4-dihydroxyphenyl)-3-buten-2-one (3), 3,4-dihydroxybenzaldehyde (4), and protocatechuic acid methyl ester (5), respectively. This study reports the first isolation of compounds 1-3 and 5 from P. linteus. In addition, all phenolic compounds stimulated proliferation of the osteoblast-like cells and increased their ALP activity in a dose-dependent manner ($10^{-8}$ to $10^{-1}\;mg/mL$). The present data demonstrate that phenolic compounds in P. linteus stimulated mineralization in bone formation caused by osteoporosis. The bone-formation effect of P. linteus seems to be mediated, at least partly, by the stimulating effect of the phenolic compounds on the growth of osteoblasts.

• Journal of the Ergonomics Society of Korea
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• v.31 no.1
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• pp.211-217
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• 2012

Objective: The aim of this study is to show a correct application procedure using the compact Korean anthropometric data application program called Korean Human Scale(KHS) for anthropometric design. Background: The nation-wide anthropometric survey project called 'Size Korea' developed KHS and distributed it to the public on the web site. But some insufficiency of the current web service of KHS misleads the users; they just put their own statue and pick up a meaningless data for a body dimension. Method: This study provides five steps to follow to read appropriate data from KHS for an anthropometric design. Results: As a case study, the depth dimension of the supervisory and control console used in the Korea nuclear power plant was determined following the procedure and compared with the console design guideline recommendation. Conclusion: The supplementary anthropometry table should be added on the web service of KHS for users to read a meaningful data for design. Application: If properly used, the KHS has a lot more potential application area than users can expect such as in control center design area.

• Journal of Korean Medical classics
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• v.24 no.6
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• pp.39-47
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• 2011

The study is a new way of treating and preventing various diseases and promoting health by means of music specially picked and designed to produce Qi fitting to an individual person in the areas of the structure of human body, physiological function, pathological change, diagnosis and treatment. Oriental medicine music therapy is based on the concept and methodology of the Oriental Medicine, actually meaning the Oriental Medicine, that is specialized in controlling the human biological energy, the Qi, and in coordinating human body and mind which are easy to be unbalanced. The seven emotions affect the change of Qi. The weakness and strength of seven emotions can induce constraint of Qi, the seven emotions music therapy and relieving constraint music therapy can be used in this case.

• Nutritional Sciences
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• v.9 no.4
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• pp.273-279
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• 2006

The purpose of this study was to determine the independent and the combined effects of cell cultured Acanthopanax senticosus extracts (ASE) supplementation and swimming exercise on body weight, lipid profile, carnitine and leptin levels in C57 BL/6J mice. Forty C57BL/6J mice were divided into four groups: non-supplement and non-exercise (NSNE); non-supplement and exercise (NSE); supplement and non-exercise (SNE); supplement and exercise (SE) mice. They were allowed free access to food and water. The exercised groups were forced to swim (1hr, 6 days a week) in a water bath for 12 weeks. The supplemented groups were fed Cell cultured ASE (0.5 g/kg body weight/day) for 12 weeks. In this study, we found that the combination of Cell cultured ASE supplementation and exercise significantly decreased liver triglyceride (TG) level and serum leptin level but significantly increased serum HDL-cholesterol level compare to control (NSNE) group. These improved lipid profiles and decreased serum leptin would have positive effects on obesity and cardiovascular disease.

• Journal of the Korean Society of Safety
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• v.28 no.3
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• pp.56-62
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• 2013

The occurrence of the ventricular fibrillation is directly dependent on the magnitude and duration of the current. The current which flows through the human body is proportional to the touch voltage applied across the body and is in inverse proportion to the impedances in the circuit. The circuit impedances consist of human body impedance, line impedance, equipment impedance, earth terminal impedance and impedance of shoes which a person put on. The impedance of shoes greatly affect the severity of the electric accidents. The human body impedances relevant to the contact areas, contact conditions, current paths and touch voltages are already determined in the IEC 60479-1. However, the impedance of shoes is ignored or substituted by a simple value because of the absence of the sufficient data. For example, the impedance of shoes plus ground contact resistance is postulated to be $1,000{\Omega}$ in the IEC 61200-612. In IEEE 80, the shoe resistance plus ground contact resistance is assumed to be bare foot with ${\rho}/4b{\Omega}$. In this paper, we measured and analyzed the impedance of shoes with respect to conditions such as applied weight, environment variables and voltages. The results showed that the impedance of shoes is dependent on environment variables regardless of the types of shoes. Most of shoes showed the correlation with the applied force, whereas a few shoes showed characteristics related to the applied voltage. In terms of severity of electric shock, one thirds of test samples indicated to be dangerous in saltwater conditions.

• Nutrition Research and Practice
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• v.17 no.6
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• pp.1238-1254
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• 2023

BACKGROUND/OBJECTIVES: Weight loss via a mobile application (App) or a paper-based diary (Paper) may confer favorable metabolic and anthropometric changes. SUBJECTS/METHODS: A randomized parallel trial was conducted among 57 adults whose body mass indices (BMIs) were 25 kg/m² or greater. Participants randomly assigned to either the App group (n = 30) or the Paper group (n = 27) were advised to record their foods and supplements through App or Paper during the 12-week intervention period. Relative changes of anthropometries and biomarker levels were compared between the 2 intervention groups. Untargeted metabolic profiling was identified to discriminate metabolic profiles. RESULTS: Out of the 57 participants, 54 participants completed the trial. Changes in body weight and BMI were not significantly different between the 2 groups (P = 0.11). However, body fat and low-density lipoprotein (LDL)-cholesterol levels increased in the App group but decreased in the Paper group, and the difference was statistically significant (P = 0.03 for body fat and 0.02 for LDL-cholesterol). In the metabolomics analysis, decreases in methylglyoxal and (S)-malate in pyruvate metabolism and phosphatidylcholine (lecithin) in linoleic acid metabolism from pre- to post-intervention were observed in the Paper group. CONCLUSIONS: In the 12-week randomized parallel trial of weight loss through a App or a Paper, we found no significant difference in change in BMI or weight between the App and Paper groups, but improvement in body fatness and LDL-cholesterol levels only in the Paper group under the circumstances with minimal contact by dietitians or health care providers.

• Journal of the Korean Physical Society
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• v.73 no.11
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• pp.1760-1763
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• 2018

To attain power generation with body heat, the thermal resistance matched design of the thermoelectric generator was the principal factor which was not critical in the case of thermoelectric generator for the waste heat generation. The dimension of thermoelectric legs and the number of thermoelectric leg-pairs dependent output power performances of the thermoelectric generator on the human wrist condition was simulated using 1-dimensional approximated heat flow equations with the temperature dependent material coefficients of the constituent materials and the dimension of the substrate. With the optimum thermoelectric generator design, thermoelectric generator modules were fabricated by using newly developed fabrication processes, which is mass production possible. The electrical properties and the output power characteristics of the fabricated thermoelectric modules were characterized by using a home-made test set-up. The output voltage of the designed thermoelectric generator were a few tens of millivolts and its output power was several hundreds of microwatts under the conditions at the human wrist. The measured output voltage and power of the fabricated thermoelectric generator were slightly lower than those of the designed thermoelectric generator due to several reasons.