• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.21 no.9
• /
• pp.921-932
• /
• 2010

This paper presents a dual-band array antenna based on a modified Sierpinski fractal structure. Array structure is mirror symmetric, and forms broadside radiation pattern for dual frequency band if the ports are fed with $180^{\circ}C$ phase difference between upper and lower $2{\times}1$ array. To use in-phase corporate feeding circuit, the phase inversion structure is designed by changing the position of patch and ground for upper and lower array. The dimensions of the array antenna is $28{\times}30{\times}5\;cm^3$ and the bandwidth of 855~1,380 MHz(47 %), 1,770~2,330 MHz(27 %) were achieved for -10 dB return loss. The measured gain is 9.06~12.44 dBi for the first band and 11.76~14.84 dBi for the second band. The half power beam width is $57^{\circ}$ for x-z plane and $46^{\circ}$ for y-z plane at 1,100 MHz and $43^{\circ}$ and $28^{\circ}$ at 2,050 MHz, respectively.

• Korean Journal of Clinical Laboratory Science
• /
• v.52 no.1
• /
• pp.1-17
• /
• 2020

Three-dimensional microscopic approaches in histopathology display multiplex properties that present puzzling questions for specimens as related to their comprehensive volumetric information. This information includes spatial distribution of molecules, three-dimensional co-localization, structural formation and whole data set that cannot be determined by two-dimensional section slides due to the inevitable loss of spatial information. Advancement of optical instruments such as two-photon microscopy and high performance objectives with motorized correction collars have narrowed the gap between optical theories and the actual reality of deep tissue imaging. However, the benefits gained by a prolonged working distance, two-photon laser and optimized beam alignment are inevitably diminished because of the light scattering phenomenon that is deeply related to the refractive index mismatch between each cellular component and the surrounding medium. From the first approaches with simple crude refractive index matching techniques to the recent cutting-edge integrated tissue clearing methods, an achievement of transparency without morphological denaturation and eradication of natural and fixation-induced nonspecific autofluorescence out of real signal are key factors to determine the perfection of tissue clearing and the immunofluorescent staining for high contrast images. When performing integrated laboratory workflow of tissue for processing frozen and formalin-fixed tissues, clear lipid-exchanged acrylamide-hybridized rigid imaging/immunostaining/in situ hybridization-compatible tissue hydrogel (CLARITY), an equipment-based tissue clearing method, is compatible with routine procedures in a histopathology laboratory.