• Title/Summary/Keyword: cell count

Search Result 1,422, Processing Time 0.054 seconds

Antioxidant and immuno-enhancing effects of Echinacea purpurea (American herb) in vivo

  • Gu, Yeun-Hwa;Maenaka, Toshihiro;Saito, Kiyoto;Yamashita, Takenori;Choi, In-Suk;Terai, Kaoru;Ahn, Kyoo-Seok
    • Advances in Traditional Medicine
    • /
    • v.5 no.1
    • /
    • pp.48-56
    • /
    • 2005
  • We studied the protective effect of Echinacea purpurea against radiation by evaluating changes in the peripheral blood cell count and peripheral blood antioxidant activity. Echinacea purpurea administration had a suppressive effect on radiation-induced leukopenia, especially on lymphocytes and monocytes and resulted in a faster recovery of blood cell counts. Mouse peripheral blood antioxidant activity was increased by Echinacea purpurea, and a relationship between the suppressive effect on radiation-induced leukopenia and the antioxidant effect was suggested.

Effects of Thickness, Si and Mn Contents on the Mechanical Properties of 3.3 wt%C-0.1 wt%S Thin-Section Gray Cast Iron (3.3 wt%C-0.1 wt%S 박육 주철의 기계적 성질에 미치는 두께, 규소 및 망간의 영향)

  • Lee, Woo-Jong;Kim, Tae-Hyeong;Kwon, Hae-Wook
    • Journal of Korea Foundry Society
    • /
    • v.32 no.5
    • /
    • pp.211-218
    • /
    • 2012
  • The effects of thickness, silicon and manganese contents on the mechanical properties of 3.3 wt%C-0.1 wt%S thin-section gray cast iron plates were investigated. The eutectic cell counts and volume fraction of pearlite in the matrix decreased with increased thickness and therefore the strength and hardness decreased with it. Even though the eutectic cell count increased with increased silicon content, the volume fraction of pearlite decreased and the strength and hardness decreased with it. The pearlite was refined more with increased manganese content and therefore the strength and hardness increased with it.

Multi-module Equalizer Circuit for Series-Connected Li-ion Batteries

  • Shin, Jong-Won;Seo, Gab-Su;Kim, Jong-Hoon;Cho, Bo-Hyung
    • Proceedings of the KIPE Conference
    • /
    • 2010.07a
    • /
    • pp.420-421
    • /
    • 2010
  • In this paper, a multi-module selective battery equalizer for series-connected Li-ion battery pack is proposed. Selective Equalizer (SE) scheme achieves smaller volume and lighter weight than individual cell equalizer (ICE) by minimizing the part count of bulky circuit element. However, SE scheme shows slow balancing speed when the voltage imbalance simultaneously occurs in more than one cell. The proposed multi-module overcomes the problem by employing multiple power converters. Prototype hardware is implemented and experimented with 14Ah battery cells to validate the performance of the proposed equalizer.

  • PDF

Clinical use of Acetylpromazine Malate in Ponies (Pony에 있어서 Acetylpromazine Malate의 사용경험)

  • Nam Tchi-Chou;Hwang Woo-Suk
    • Journal of Veterinary Clinics
    • /
    • v.1 no.1
    • /
    • pp.49-52
    • /
    • 1984
  • Ponies were administered at the level of 0.1mg per kg of body weight of acetylpromazine malate through the jugular vein. Sedative effect, clinical signs such as body temperature, and changes of red blood cell counts and serum glucose concentration were investigated. Sedation was induced 5 to 6 minutes after injection of acepromazine and sedative effect was lasted for 30 to 40 minutes. Responsive reactions, however, to external stimuli were remained. Change of body temperature was not observed and heart beat was increased at the stage of induction and respiratory rate was decreased during the sedative period. Red blood cell count was considerably decreased during sedation, and concentration of serum glucose showed a tendency to increase gradually from the induction.

  • PDF

Immune Suppression and Stimulation of Antioxidants II -Effect of Propyl gallate on Murine Cell Mediated Immune Functions- (항산화제의 면역억제 및 항진연구 II - 항산화제인 Propyl gallate가 세포 면역기능에 미치는 영향 -)

  • 유충규;황미경
    • Journal of Food Hygiene and Safety
    • /
    • v.5 no.1
    • /
    • pp.41-48
    • /
    • 1990
  • Propyl gallate used as an antioxidant was examined for its effects on murine immune system. As immunotoxicology assay parameters, we adopted circulating leukocytes and immunoorgan weights for pathotoxicology, delayed hypersensitivity and colloidal carbon clearance for cell mediated immuntity. Propyl gallate's effects were observed as follows; 1) Propyl gallate decreased circulating leukocyte counts, dose dependently. 2) Propyl gallate decreased delayed hypersensitivity reaction. 3) Phagocytic index were similar in the test and control groups.

  • PDF

Hematological Changes in Dogs Administrated N-Butyl Alcohol Extracts of The Korean Chinese Chives(Allium tubertosum Rottler) (부추 N-Butyl Alcohol 추출액의 투여가 개의 혈액상에 미치는 영향)

  • 이성동;김하동;박승춘;송재찬;김영홍;오태호;이근우
    • Journal of Veterinary Clinics
    • /
    • v.20 no.1
    • /
    • pp.110-114
    • /
    • 2003
  • The Korean Chinese Chives(Allium tuberosum Rottler) are a perennial herb and have been used from ancient as food and medical purpose in Korea. They are known to posses diuresis, sthemia activities and used for the treatment or anemia, haematemesis, and eczema. Recently the Korean Chinese Chives have been studied on the morphologic property, the classification of origin and chemical constituent. However there has not been studied on kg) (or 6 days and observed the hematological effects in dogs. The results are as follows, 1. The red blood cell count was significantly (P < 0.05) decreased on day 2. 2. The reduced glutathion(GSH) concentration was significantly (P< 0.05) increased on day 4 and Met-hemoglobin concentration was significantly (P< 0.05) increased on 3 hrs after administration. 3. Packed cell volume(PCV) and hemoglobin concentration were not showed significant difference during experimental periods. 4. The mean corpuscular volume(MCV) was significantly(P < 0.05) increased on 3 hours after administration.

Kaempferol inhibits the platelet-derived growth factor $\beta$-receptor tyrosine-phosphorylation and its downstream intracellular signal transduction pathway in rat aortic vascular smooth muscle cells

  • Kim, Soo-Yeon;Kim, Jin-Ho;Lim, Yong;Yoo, Hwan-Soo;Yun, Yeo-Pyo
    • Proceedings of the PSK Conference
    • /
    • 2003.10b
    • /
    • pp.108.2-108.2
    • /
    • 2003
  • Kaempferol, a flavonol compound, has been reported as the anti-oxidant and anti-angiogenic agent and it has been found to inhibit cell growth in vitro. Abnormal proliferation of vascular smooth muscle cells (VSMCs) plays an important role in development of atherosclerosis. In this study, we examined the anti-proliferative effect and its mechanism on rat aortic VSMCs treated by kaempferol. kaempferol significantly inhibited the platelet-derived growth factor (PDGF)-BB-induced proliferation of rat aortic VSMCs in concentration-dependent manner by cell count and [$^3$H]-thymidine incorporation assay. (omitted)

  • PDF

Stem cell therapy for dogs with immune-mediated hemolytic anemia

  • Yeonmi Lee;Eunju Kang;Junguk Ju
    • Journal of Animal Reproduction and Biotechnology
    • /
    • v.39 no.1
    • /
    • pp.58-61
    • /
    • 2024
  • Three different dogs who had immune-mediated hemolytic anemia (IMHA) were treated for more than two weeks with blood transfusion in an animal clinic. Despite this treatment and hospitalization, there was no clinical improvement in clinical signs as well as complete blood cell count (CBC) including hematocrit (HCT) and C-reactive protein (CRP). All cases were then injected two or three times with allogeneic stem cells through an intravenous route for treatment. Upon administrating stem cells to the IMHA dogs, clinical conditions and the indexes of HCT and CRP were clinically improved within or close to normal ranges.

Inhibitory Effect of Saengangeonbitang-gasamchilgn on Liver Fibrosis in Rat (생간건비탕가삼칠근(生肝健脾湯加三七根)이 흰쥐의 간섬유화 억제에 미치는 영향)

  • Lee, Eun;Kim, Young-Chul;Ko, Heung
    • The Journal of Internal Korean Medicine
    • /
    • v.29 no.2
    • /
    • pp.500-511
    • /
    • 2008
  • The aim of this study was to investigate the inhibitory effect of Saengangeonbitang-gasamchilgn(SGGBTGSCG) on collagen production in rat hepatic stellate cells(HSC) and on the TAA-induced chronic liver injury model in rats. Methods : 1) HSCs were treated with SGGBTGSCG extract powder(50% EtOH SGGBTGSCG, dw SGGBTGSCG). After the treatment, MTT assay, BrdU assay and procollagen assay were done. In addition, gene expressions of collagen type $1{\alpha}2$, ASMA, TIMP1, and TIMP2, all of which are known to be associated with liver fibrosis, were analyzed by RT-PCR. 2) Liver fibrosis was developed in rats by injection of TAA 3 times a week for 5 weeks. After the SGGBTGSCG-treatment, body weight, liver & spleen weight, liver function test, the complete blood cell count and the change of portal pressure were studied. Results : In MTT assay, SGGBTGSCG significantly decreased the viability of HSCs in a dose-dependent manner. In BrdU assay, SGGBTGSCG significantly inhibited the HSC proliferation in a dose-dependant manner. In procollagen assay, SGGBTGSCG decreased procollagen production by HSC. In the change of rats' liver and spleen weight, TAA+SGGBTGSCG groups showed little difference compared with TAA-only group. In the liver function test, SGGBTGSCG decreased the serum level of ALT, AST, and Alp elevated by TAA. In the complete blood cell count, SGGBTGSCG significantly decreased WBC elevated by TAA and increased RBC and Hct lowered by TAA. In the change of portal pressure, SGGBTGSCG decreased portal pressure elevated by TAA. Conclusions : These results suggest that SGGBTGSCG is beneficial in the treatment of cirrhotic patients as well as for patients with chronic hepatitis.

  • PDF

Increase of the Treatment Efficiency of a Pharmaceutical Wastewater and a Paperboard Wastewater by the addition of Bacteria (세균첨가에 의한 제약폐수 및 판지폐수의 처리효율의 향상)

  • 이형춘
    • KSBB Journal
    • /
    • v.15 no.4
    • /
    • pp.370-374
    • /
    • 2000
  • Some bacterial strains isolated from activated sludges and media and type cultures were cultivated in a pharmaceutical wastewater and a paperboard wastewater and added during batch treatment of those wastewaters in order for these strains to increase the treatment efficiency. Bacillus sp(PC-3) isolated from the charcoal media of the pharmaceutical wastewater plant grew remarkably over there strains in that wastewater and the viable cell count after 24hr cultivation was $1.1{\times}10^6m/L$. Bacillus subtills KCTC 1028 a type strain grew best in the paperboard wastewater and the viable cell count after 24hr cultivation was $1.1{\times}10^7m/L$. Addition of PC-3 in a batch treatment of the pharmaceutical wastewater increased COD removal by 18% after 8 day. And addition of Bacillus subtills KCTC 1028 in a batch treatment of the paperboard wastewater increased COD removal by 14% only after 24hy Bacillus subtills DCTC 1028 was though to be able to be produced economically using alcohol distillery wastewaters from starch material.

  • PDF