• Nutritional Sciences
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• v.9 no.3
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• pp.173-178
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• 2006

The purpose of this study was to investigate the effects of wax gourd on body weight, body fat, triglyceride, leptin and fat cell size in rats fed medium fat Male Sprague Dawley rats were fed with experimental diet containing total dietary fat at 20% of calorie with wax gourd (WG) for 4 weeks. Forty rats were divided into 4 groups including control, 5, 10, and 15% (w/w) WG supplement The results showed that weight gain was significantly higher in 5% WG than that in control (p<0.05), but was not different among the WG supplement groups. Total fat weight was significantly decreased in both 10 and 15% WG supplement groups than that of control. The levels of triglycerides and free fatty acids in the plasma were significantly decreased, particularly in 15% WG supplement group (p<0.05). The levels of leptin was not significantly different among the experimental groups. Fat cell size was significantly decreased in WG supplement groups compared to that of control group (p<0.05). Correlation among the parameters demonstrated that weight gain correlated positively with total fat weight, the levels of leptin and triglycerides. Taken these results together, 15% WG supplement diet substantially reduces total fat weight, triglycerides and free fatty acids levels and fat cell size in the rat fed midium fat.

• Microbiology and Biotechnology Letters
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• v.22 no.1
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• pp.80-84
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• 1994

In order to induce the rapid alcohol fermentation through the increases of the cell density in a continuous alcohol fermentation of naked barley, the single-cultivation with S. cerevisiae IS-019(SCM, ordinary control), mixed-cultivation with Saccharomyces uvarum IS-026 having a flocculent ability and S. cerevisiae IS-019(MCM), and mash recirculation by single-cultivation of S. cerevisiae IS-019(MRM) modes were investigated. The cell mass in the mixed-cultivation mode was about 10% higher than that of ordinary control but the final alcohol yield was slightlyl decreased. When recycled the mash with the flow rate of 7 l/h from V$_{6}$ to V$_{5}$ fermentors under the ordinary control, the cell density was distributed at 140~170$\times $10$^{6}$ cell/ml depending upon the fermentorsorders, higher about 20% than that of the ordinary control. Under these conditions the alcohol productivity of the maximum and the overall was 12.16 g/l$\cdot $h with an alcohol of 7.6% at the V$_{5}$ fermentor and 1.19 g/l$\cdot $h with an alcohol of 8.94%, respectively. For higher cell mass it was more effective to apply the mash recirculation mode with the single-cultivation of S. cerevisiae IS-019 in a pilot scale multi-stage CSTR.

• Journal of the Korean Society for Railway
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• v.12 no.5
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• pp.772-777
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• 2009

The development of fuel cell hybrid power system, as a next generation power system to promote clean energy which will mitigate the continued global warming, has demonstratd a significant progress in passenger vehicle applications. Also, in case of railway vehicles in non-electrified railway lines, the adoption of fuel cell hybrid power system is being studied among well-known manufacturers. This paper introduces both the configuration and the control strategy of fuel cell hybrid power system to apply to a light electronic railway vehicle having a repeated driving pattern of acceleration, coasting and deceleration. The simulation results demonstrate the viability of the proposed power system design and its control strategy.

• Journal of Electrical Engineering and Technology
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• v.8 no.2
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• pp.304-315
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• 2013

In this paper, analysis of cascaded H-bridge multilevel inverter in DTC-SVM (Direct Torque Control-Space Vector Modulation) based induction motor drive for FCEV (Fuel Cell Electric Vehicle) is presented. Cascaded H-bridge multilevel inverter uses multiple series units of H-bridge power cells to achieve medium-voltage operation and low harmonic distortion. In FCEV, a fuel cell stack is used as the major source of electric power moreover the battery and/or ultra-capacitor is used to assist the fuel cell. These sources are suitable for utilizing in cascaded H-bridge multilevel inverter. The drive control strategy is based on DTC-SVM technique. In this scheme, first, stator voltage vector is calculated and then realized by SVM method. Contribution of multilevel inverter to the DTC-SVM scheme is led to achieve high performance motor drive. Simulations are carried out in Matlab-Simulink. Five-level and nine-level inverters are applied in 3hp FCEV induction motor drive for analysis the multilevel inverter. Each H-bridge is implemented using one fuel cell and battery. Good dynamic control and low ripple in the torque and the flux as well as distortion decrease in voltage and current profiles, demonstrate the great performance of multilevel inverter in DTC-SVM induction motor drive for vehicle application.

• Journal of Periodontal and Implant Science
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• v.29 no.3
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• pp.607-621
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• 1999

This study examined the human fibroblasts cell attachment to commercially pure titanium surface which had been instrumented by 3 types of periodontal instruments. Commercially pure titanium plates were uniformly scaled using plastic, stainless steel, titanium curette. these all experimental groups 65 undirectional strokes with the designated curettes. Alteration of the surfaces due to instrumentation was evaluated by Form Talysurf(R) and reported as Ra value(mean surface roughness). Then other experimental groups were immersed in a cell suspension of human gingival fibroblasts($1{\times}10^5$ cell/ml). After 3 days of culture, cell attachment and morphology was observed by SEM, and attached cell were counted by Hemocytometer. A significant difference in mean Ra value was observed for surface instrumented by metal curette compared to either control surface or surface instrumented by the plastic curette(P<0.01). No stastically significant difference was noted between control surface and those instrumented by the plastic curette. SEM observation showed that cell morphology and attachment to the commercially pure titanium plate was similar appearance on the all experimental groups. Experimental groups instrumented by titanium curette and stainless steel curette were more attached cell number than control group, but experimental group instrumented by plastic curette were similar with control groups(P<0.01). In summary, metal curette produced an significant alteration of the commercially pure titanium surface and more favorable surface topography for cell attachment. Otherwise plastic curette was insignificantly altered the commercially pure titanium surface(P<0.01).

• Microbiology and Biotechnology Letters
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• v.36 no.4
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• pp.307-313
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• 2008

The yeast surface expression system, pCTXYN (6.8 kb), of Bacillus endoxylanase gene (xynB, 642 bp) was constructed and introduced into Saccharomyces cerevisiae EBY100 cell. The transformed yeast cell showing the highest endoxylanase activity was selected through the active staining of colonies grown on YPDG medium containing xylan. With the yeast transformant, EBY100/pCTXYN, grown on galactose containing medium, it was found that the endoxylanase was successfully displayed on the yeast cell surface and the xylooligosaccharides were efficiently produced from xylan. The most of endoxylanase activity was detected in the cell fraction and reached about 1.9 unit/mL after 48 h cultivation. The optimized conditions for xylooligosaccharides production from xylan were determined as follows: substrate and its concentration, oat spelt xylan 6%; concentration of yeast whole-cell, 5 unit/mL; temperature, $50^{\circ}C$, and reaction time $2{\sim}4\;h$. When the oat spelts xylan and corncob xylan were hydrolyzed by treatment with cell surface-displayed endoxylanase, xylotriose was formed as a main product.

• Journal of Institute of Control, Robotics and Systems
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• v.11 no.7
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• pp.578-586
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• 2005

Air mattress is now used widely to prevent the pressure ulcer by reducing the localized pressure peaks. The pressure control method based on the anthrophometric model of an air-cell mattress developed in this study is presented. The air-cell mattress has 18 cylindrical air cells made of porous material allowing air leakage. Even though the air leakage can contribute to reducing the development of pressure ulcer by lowering the pressure peak, temperature and humidity, the air pressure changes with time and the desired air-cell pressure has to be determined as an optimal value for each user. To select the desired air-cell pressure, we first divide the parts of the body into four sections such as head, trunk, hip, and leg. Then, the pressure of each section grouped with air-cells is calculated from the weight of each part estimated from the individual height and body weight. Air supply system for the air-cell mattress is implemented by using four electronic solenoid valves and an air compressor, and it is driven by a real-time microcontroller. We experimented with five subjects of the contact pressure on skin. The experimental results show that the proposed air-cell mattress is effective for the prevention of the pressure ulcer.

• Journal of Advanced Navigation Technology
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• v.15 no.4
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• pp.562-570
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• 2011

In this paper, a distributed mobile relay power control (DMRPC) scheme for maximizing individual cell throughput is proposed for mobile relay aided multi-cell orthogonal frequency division multiplexing (OFDM)-time division duplex (TDD) system. In the system with DMRPC, the power levels of relay's are controlled by individual cell without cell cooperation and signalling overhead. It is demonstrated by numerical simulation that DMRPC provides the better cell throughput performance than either the full power relay aided system or conventional system without relay does. Moreover, it is also shown that relay aided systems with DMRPC, and the conventional system have almost identical cell edge throughput, while full power relay aided systems show worse performance in cell edge throughput.

• BMB Reports
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• v.57 no.5
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• pp.232-237
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• 2024

This study investigated how adipose tissue-derived mesenchymal stem cells (AT-MSCs) respond to chondrogenic induction using droplet-based single-cell RNA sequencing (scRNA-seq). We analyzed 37,219 high-quality transcripts from control cells and cells induced for 1 week (1W) and 2 weeks (2W). Four distinct cell clusters (0-3), undetectable by bulk analysis, exhibited varying proportions. Cluster 1 dominated in control and 1W cells, whereas clusters (3, 2, and 0) exclusively dominated in control, 1W, and 2W cells, respectively. Furthermore, heterogeneous chondrogenic markers expression within clusters emerged. Gene ontology (GO) enrichment analysis of differentially expressed genes unveiled cluster-specific variations in key biological processes (BP): (1) Cluster 1 exhibited up-regulation of GO-BP terms related to ribosome biogenesis and translational control, crucial for maintaining stem cell properties and homeostasis; (2) Additionally, cluster 1 showed up-regulation of GO-BP terms associated with mitochondrial oxidative metabolism; (3) Cluster 3 displayed up-regulation of GO-BP terms related to cell proliferation; (4) Clusters 0 and 2 demonstrated similar up-regulation of GO-BP terms linked to collagen fibril organization and supramolecular fiber organization. However, only cluster 0 showed a significant decrease in GO-BP terms related to ribosome production, implying a potential correlation between ribosome regulation and the differentiation stages of AT-MSCs. Overall, our findings highlight heterogeneous cell clusters with varying balances between proliferation and differentiation before, and after, chondrogenic stimulation. This provides enhanced insights into the single-cell dynamics of AT-MSCs during chondrogenic differentiation.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.21 no.4
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• pp.952-960
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• 1996

In this paper, a new overload control scheme is proposed for a control system in ATM switching system. The proposed control scheme includes a counter that conunts the number of accepted calls and is decreased at cach D time interval. In overload condition of call processor, the control scheme detects over load condition when the counter value reaches a certain threshold value. Under overload condition, processor utilization is measured and the value of the D is updataed according to the difference between measured processor utilization and target utilization. A new call is accepted accepted only if the value of the counter is less than the threshold value. In overflow condition of cell traffic, accept probability of new call is reduced exponetially according to the elapsed time. The results of simulation show that the proposed overload contorl scheme maintains the target utilization very well under the various processor overload conditions and reduces the cell loss probability under the cell overflow conditions.