• 제목/요약/키워드: cell control

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제조가 마우스 Natural killer 세포(細胞) 활성(活性)에 미치는 영향(影響) (The effect of Holotrichia on Natural killer Cell Activity in Mice)

  • 김기열;김종대;정지천;남경수
    • 대한한의학회지
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    • 제19권2호
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    • pp.313-325
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    • 1998
  • The effect of Holotrichia on natural killer cell activity in normal mouse were studied. 1. The oral administration of Holotrichia increased spleen weight about 21.1% and also cell numbers of spleen compared to control mice group. 2. The cytotoxicity of effector cell was most effectively induced in a ratio of 50 : 1(effector/target cell). 3. Cytotoxicity of effector cells was. increased about 24% as compared with control group in in vivo test. 4. On the other hand, the administration of Holotrichia original solution showed significant increase the cytotoxicity. The cytotoxicity was increased concentration dependently. 5. The cytotoxicity by $^{3}H-thymidine$ incorporation assay showed similar effect with LDH enzyme method. 6. In the purified NK cells, the cytotoxicity was increased about 31% as compared with control group in in vivo system and the ratio of cytotoxicity was generally more increased than that of partially purified NK cell. 7. In vitro experimet of the purified NK cells, the cytotoxicity was increased 11.8% as compared with control group and the ratio of cytotoxicity was also more increased than that of partially purified NK cell. These results suggest that Holotrichia is administrated to mice with malignant tumors, the increase of NK cell activity may occur and affect tumor cells.

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In vivo와 in vitro에서 김치가 혈액성상과 면역세포배양에 미치는 영향 (The Effects of Kimchi on Hematological and Immunological Parameters in vivo and in vitro)

  • 송영선;김미정;권명자;송영옥;이은경;윤현주
    • 한국식품영양과학회지
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    • 제26권6호
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    • pp.1208-1214
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    • 1997
  • This study was designed to know the effect of kimchi on the hematological and immunological parameters in vivo and in vitro, respectively. To study the effects of kimchi on the hematological parameters, rats(S.D., male) were divided into 4 groups and fed diets containing of 3%, 5% and 10% kimchi or kimchi free diet(control) for 6 weeks. The results of CBC(complete blood cell) tests obtained from the bloods of rates were as follows ; In 10% kimchi group, the level of WBC(white blood cells), RBC(red blood cells), Hgb(hemoglobin), Hct(hematocrit) were increased significantly than those of control group(p<0.05). MCV(mean corpuscular volume), one of the red cell indices, was also increased significantly in the animals fed 10% kimchi(p<0.05). RDW(Red cell distritution width) and PCT(plateletcrit) was lowest in 10% kimchi group(p<0.05). To examine the effects of kimchi on immune cell growth in vitro, three types of mouse immune cells-spleen cells, bone marrow cells, thymus cells-were cultured with extracts of salted Chinese cabbage, fresh kimchi and fermented kimchi(for 1 week) for 12 or 20 days. Control was supplemented with PBS(phosphate buffer saline) excluding kimchi extract. The results of spleen cell, bone marrow cell, and thymus cell cultures showed similar tendency: control medium accelerated death of cells, extracts of salted Chinese cabbage reduced the rate of cell death, and extracts of fresh kimchi and fermented kimchi promoted cell growth. From these results, it could be suggested that kimchi possibly has an effect on the hematopoietic ability and increases immune cell development and growth in vivo.

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NTacSam:SD 골수 세포의 증식에 100Hz PWM 저출력 광 조사가 미치는 효과 (Effect of the 100Hz PWM Low Power Light Irradiation in Proliferation of NTacSam:SD Bone-marrow Cell)

  • 천민우;김성환;이호식;박용필
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2008년도 춘계학술대회 논문집
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    • pp.10-11
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    • 2008
  • We developed the equipment palpating cell proliferation using a high brightness LED. This equipment was fabricated using a micro-controller and a high brightness LED, and designed to enable us to control light irradiation time, intensity, frequency and so on. Especially, to control the light irradiation frequency, FPGA was used, and to control the change of output value, TLC5941 was used. Control stage is divided into 30 levels by program. Consequently, the current value could be controlled by the change of level in Continue Wave(CW) and Pulse Width Modulation(PWM), and the output of a high brightness LED could be controlled stage by stage. And then, each experiment was performed to irradiation group and non-irradiation group for bone marrow cells. MIT assay method was chosen to verify the cell increase of two groups and the effect of irradiation on cell proliferation was examined by measuring 590nm transmittance of ELISA reader. As a result, the cell increase of bone marrow cells was verified in irradiation group as compared to non-irradiation group.

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연료전지 발전시스템을 이용한 축소형 철도차량의 운전곡선 추종에 따른 추진제어장치 특성 고찰 (A Study on Propulsion Control Device Characteristics of Small-scale Electric Railway Vehicle according to Driving Curve Tracking using Fuel Cell Generation System)

  • 정노건;창상훈;김재문
    • 전기학회논문지
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    • 제64권12호
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    • pp.1804-1809
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    • 2015
  • The study in railway system to apply a fuel cell system with high efficiency and mobility than other renewable energy is being actively conducted. It is needed a analysis on load characteristics and control method of rolling stock in order to apply to rolling stock. This paper presents study on control small-scale prototype power converter electric railway vehicle using fuel cell generation system. Experiment is conducted through real fuel cell generation system and reference speed applying the driving curve of the actual electric railway vehicle was applied. Also, output voltage of boost converter is controlled considering characteristic of fuel cell. And it was confirmed characteristic according to powering and regeneration of inverter.

ATM 멀티플렉서에서 우선순위 제어에 의한 음성전송효율 및 버퍼관리에 관한 연구 (A Study on the Voice Traffic Efficiency and Buffer Management by Priority Control in ATM Multiplexer)

  • 이동수;최창수;강준길
    • 한국통신학회논문지
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    • 제19권2호
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    • pp.354-363
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    • 1994
  • 본 논문은 광대역 ISDN에서 음성 서비스를 효율적으로 제공하는 방법에 관한 연구이다. 음성은 그 특성상 유음구간과 북음구간으로 나누어지며, 음성활성검출에 의하여 실제로 말을 하는 동안만 전송이 이루어질 수 있도록 음성 트래픽을 발생한다. 본 논문에서는 ATM통신망에서 음성을 음성활성검출과 삽입(Embedded) ADPCM으로 코딩하고, 멀티플렉서에서 셀 폐기를 통하여 트래픽을 제어하는 알고리즘에 관하여 연구하였다. 트래픽 제어는 버퍼에 임계값을 주어, 버퍼의 상태가 임계값을 초과하는 경우에 낮은 우선순위를 갖는 음성 셀을 폐기하는 셀 폐기 알고리즘을 사용하였다. 셀 손실 확률, 큐 크기, 평균지연등을 성능분석 파라메터로 설정하고, 트래픽 제어 알고리즘의 성능을 평가하기 위하여 컴퓨터 시뮬레이션하였다. 이를 통하여 센 폐기방식에 의한 트래픽 제어가 음성의 질을 많이 저하시키지 않으면서도 트래픽 제어를 하지 않을 때에 비하여 전송 대역 이득을 향상시킨다는 것을 확인하였다.

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Indomethacin으로 유발된 생쥐의 위 점막 손상에 대한 향사평위산(香砂平胃散)의 보호 효과 (The Effects of Hyangsapyeongwisan on Gastric Mucosal Lesions Induced by Indomethacin)

  • 최흥민;임성우
    • 대한한방내과학회지
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    • 제25권3호
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    • pp.518-528
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    • 2004
  • This study was carried out to investigate the effects of Hyangsapyeongwisan(HP) on gastric mucosal lesions induced by indomethacin in mice. The control group consisted of gastro-inflammation elicited mice. The sample group consisted of mice given HP after onset of gastro-inflammation. In common morphological and histochemical change, various cell abnormalities were observed in the control group, such as mucous surface cell, peanut cell, surface epithelial cell, goblet cell abnormalities, all caused hemorrhagic erosion. The sample group was the same as the control group. In the immunohistochemical change, the distributions of COX-I, BrdU treated with HP were notably higher than those of the control group(p$NF-{\kappa}B$, COX-2, PKC, IL-12B in mice treated with HP were notably lower than those of the control group(p

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태양전지 온도 센싱만을 통한 태양광 발전시스템의 최적 운전전압에 관한 연구 (A Study on the Optimal Voltage for MPPT Obtained by only Surface's Temperature of Solar Cell)

  • Minwon Park;In-Keun Yi
    • 대한전기학회논문지:전기기기및에너지변환시스템부문B
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    • 제53권4호
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    • pp.269-275
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    • 2004
  • Photovoltaic(PV) system has been studied and watched with keen interest due to a clean and renewable power source. But, the output power of PV system is not only unstable but uncontrollable, because the maximum power point tracking (MPPT) of PV system is still hard with the tracking failure under the sudden fluctuation of irradiance. Authors suggest that the optimal voltage for MPPT be obtained by only solar cell temperature. Having an eye on that the optimal voltage point of solar cell is in proportion to its panel temperature, with operating the power converter whose operating point keeps its input voltage to the optimal voltage imagined by the surface's temperature of PV panel, the maximum power point becomes tenderly possible to be tracked. In order to confirm the availability of the proposed control scheme. And both control methods are simulated not only on the various angle of sampling time of switching control, but also with the real field weather condition. As the results of that, the conversion efficiency between PV panel and converter of the proposed control scheme was much better than that of the power comparison MPPT control, and what is better, the output voltage of PV panel was extremely in stable when the optimal voltage for MPPT is obtained by only solar cell temperature.

ATM 교환기에서 셀 및 윈도우 카운터를 이용한 우선순위 제어 (Priority Control Using Cell and Windows Counter in ATM Switchs)

  • 김변곤;서혜영;장정정;박기홍;한철민;김남희
    • 한국콘텐츠학회논문지
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    • 제6권3호
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    • pp.1-11
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    • 2006
  • 정보통신기술의 발달로 광대역 통신망에서의 서비스들은 지연, 셀 손실 확률, 지터 요구사항들이 트래픽의 특성에 따라 매우 다양하다. 따라서 광대역망에서 다양한 트래픽의 종류에 따른 셀 손실율과 셀 지연율의 요구사항을 만족시킬 수 있는 제어시스템의 설계는 매우 중요한 요소이다. 본 논문에서는 트래픽의 각 클래스 타입에 따라 셀 카운터와 윈도우 카운터를 이용한 우선순위 제어 기법을 제안하였다. 제안한 기법에서는 요구된 서비스의 질을 만족시키기 위해 셀 카운터와 윈도우 카운터의 비교에 의해 얻어진 셀 손실과 지연 요소를 획득하여 우선순위 제어를 수행하였다. 그리고 컴퓨터 시뮬레이션을 통하여 성능을 평가하였다. 시뮬레이션 결과 셀 손실은 비디오, 데이터, 음성 순서로, 지연시간은 비디오, 음성, 데이터 순서의 결과를 보여 각 클래스의 요구조건을 만족시키는 우선순위제어 기법임을 확인할 수 있었다.

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회전축의 정밀 토그 발생용 직류 발전기 제어장치의 설계 및 성능평가에 관한 연구 (Design and Performance Evaluation of DC Generator Control System for Cortrolling Torque of Rotating Shaft)

  • 김갑순;강대임;안병덕
    • 한국정밀공학회지
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    • 제11권6호
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    • pp.50-56
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    • 1994
  • A DC generator control system was designed to control the torque of a rotating shaft precisely. The control system is composed of a strain gage type torque cell, a torque cell amplifier, a computer, a D/A converter, a error detector, a DC voltage amplifier and a resistor. The response test under unit step input and the dynamic stability test for the designed control system were carried out. It was confirmed that the settling time from the response test is about 4 s and the error from the dynamic stability test is less than 0.06% of rated output of torque cell. The designed control system may be used to control a DC generator which may be used to apply torque to a rotating shaft.

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PDGF와 $TGF-{\beta}1$이 배양 인체 치은 섬유모세포와 치주인대세포의 활성에 미치는 영향 (EFFECT OF PDGF AND $TGF-{\beta}1$ ON CELL ACTIVITY OF HUMAN GINGIVAL FIBROBLAST AND PERIODONTAL LIGAM ENT CELL IN VITRO)

  • 정순규;남궁혁;신형식
    • Journal of Periodontal and Implant Science
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    • 제25권1호
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    • pp.133-145
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    • 1995
  • The migration and proliferation of periodontal ligament cells are desired goal of periodontal regeneration therapy. PDGF and $TGF-{\beta}1$ are well known to regulate the cell activity of mesenchymal origin cell. The purpose of this study was to determine the effects of these growth factors on human gingival fibroblast and periodontal ligament cell actvity, and to identify the regulatory effect of $TGF-{\beta}1$ on the response to PDGF by MIT assay. Human gingival fibroblast and periodontal ligament cells were cultured from extracted teeth for non-periodontal reason. Cultured human gingival fibroblast and periodontal ligament cells in vitro were treated with polyperpetide growth factor PDGF and $TGF-{\beta}1$ in both a dose and time - dependent manner. Cell morphology were determined by inverted microscope and cell acitivity were determined by MIT assay. The result of this study demonstrated that PDGF and $TGF-{\beta}1$ were not changed the morphology of these cell compared with control group. PDGF or $TGF-{\beta}1$ increased cell activity of periodontal ligament cell in dose and time dependent manner but gingival fibroblast were decreased to the level of control group at third day. Additionally, incubation with $TGF-{\beta}1$ addition to PDGF resulted in a enhanced cell activity of PDGF. Therefore, cell acitivty of gingival fibroblast were not changed compared with control group. This stiudy demonstrates that PDGF and $TGF-{\beta}1$ are major mitogens for human periodontal ligament cell in vitro, and $TGF-{\beta}1$ is a regulator of cell activity to PDGF in human gingival fibroblast and periodontal ligament cell.

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