• Title/Summary/Keyword: cell area

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Enzyme Inhibitory and Anti-Proliferation Effects of Peanut Skin Extracts Depending on Cultivar (품종별 땅콩 종피 추출물의 효소저해활성 및 암세포주 증식억제 효과)

  • Kim, Min Young;Kim, Hyun-Joo;Lee, Yu-Young;Kim, Mi Hyang;Lee, Jin Young;Lee, Byoungkyu;Lee, Byong Won
    • The Korean Journal of Food And Nutrition
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    • v.32 no.5
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    • pp.511-521
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    • 2019
  • The purpose of this study was to investigate the inhibitory effect of enzyme activity and anti-proliferation of human cancer cell lines (HCT 116, NCI-H460 and MCF-7) of peanut skin depending on cultivars (Arachis hypogaea L. cv. K-Ol, cv. Sinpalkwang, cv. Daan, cv. Heuksaeng) and extraction solvent. Peanut skin was extracted with 80% ethanol, 80% methanol, 80% acetone, and distilled water, followed by analysis of the enzyme inhibitory activity and anticancer activity. Methanol extract of Daan cultivar most effectively inhibited ${\alpha}$-gluosidase (65.08%, 0.025 mg/mL), tyrosinase (82.49%, 2 mg/mL) and ACE (73.61%, 10 mg/mL). The inhibitory effect of peanut skin extracts on colon cancer cell (HCT-116), lung cancer cell (NCI-H460) and breast cancer cell (MCF-7) growth were investigate using MTT assay. The highest anti-proliferation of cancer cell line of peanut skin extracts was observed in the methanol extract of Daan cultivar. The cell viability on HCT 116, NCI-H460 and MCF-7 cell lines of methanol extracts from peanut skin of Daan cultivar was 48.13%, 41.03%, and 36.02% at $200{\mu}g/mL$, respectively. These results suggest that peanut skin extracts may mediate physiological activity, and provide valuable information for the use of peanut byproduct as a functional food material.

Structure and Cytochemistry of Skin in Spined Loach, Iksookimia longicorpus (Pisces, Cobitidae) (왕종개 Iksookimia longicorpus (Pisces, Cobitidae) 피부 구조와 세포화학적 특징)

  • Park, Jong-Young;Kim, Ik-Soo
    • Korean Journal of Ichthyology
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    • v.12 no.1
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    • pp.25-32
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    • 2000
  • The structure of skin was studied in Iksookimia longicorpus based on the micro-anatomical investigation of skin fragments taken from four regions. The epidermis was distinguished by two types of skin glands, a small mucous cell and a large club cell. The mucous cell was acid sulfomucins (some sialomueins) but the club cell did not give any histochemical tests for mucosubstances. The presence of a well defined lymphatic system with small lymphocytes was established in the stratum germinativum layer of the epidermis. A large number of blood capillaries run very close to each other just below the basement membrane, and a definite area giving AB and PAS positive was present between the basement membrane and scale.

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Perfonnance Evaluation of Single Cell and Stack of PolymerElectrolyte Fuel Cell by Using Transfer Printing Technique

  • KIM, CHANG SOO;CHUN, YOUNG-GAB;PECK, DONG-HYUN;YANG, TAE-HYUN
    • Transactions of the Korean hydrogen and new energy society
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    • v.11 no.1
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    • pp.19-27
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    • 2000
  • The polymer electrolyte membrane fuel cell (PEMFC) system was developed. In order to enhance the performance of membrane electrode assembly (MEA), the transfer printing method of the electrocatalyst layer on membrane was developed. The $H_2/O_2$ single cell with an electrode area of $50cm^2$ was fabricated and tested using 20 wt.% Pt/C as an electrocatalyst and the commercial and hand-made MEA such as Nafion 115, Hanwha, Dow, Flemion T and Gore Select. The 100-cell PEMFC stack with an active electrode area of $300cm^2$ was designed and fabricated using 40 wt.% Pt/C and 30 wt.% Pt-Ru/C as a cathode and anode electrocatalysts, respectively. The performance of PEMFC system was obtained to be 7kW (250A at 28V) and 3.5kW (70A at 50V) at $80^{\circ}C$ by flowing $H_2/air$ and methanol reformed fuel gas/air, respectively.

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Effects of anode surface area and methylene blue dye treatment on the power density of microbial fuel cell with sponge and carbon nano tube electrode (음극 전극 표면적과 메틸렌블루 염색이 스펀지 탄소나노 튜브 전극 미생물 연료전지의 전력수율에 미치는 영향)

  • Lee, Chae-Young;Park, Su-Hee;Song, Young-Chae;Woo, Jung-Hui;Yoo, Kyu-Seon;Chung, Jae-Woo;Han, Sun-Kee
    • Journal of Korean Society of Water and Wastewater
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    • v.26 no.6
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    • pp.883-888
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    • 2012
  • Anode electrode is one of the most important factors in microbial fuel cell (MFC). This study was conducted to investigate the effects of mediator as methylene blue (MB) and electrode surface area on the power density of MFC with sponge and carbon nano tube (CNT) electrode (SC). The SC electrode with MB (MC) showed the maximum power density increased from 74.0 $mW/m^2$ to 143.1 $mW/m^2$. The grid shaped sponge and CNT (GSC) electrode showed the maximum power density of 209.2 $mW/m^2$ due to the increase of surface area from 88.0 to 152.0 $cm^2$. The GSC electrode with MB (GMC) revealed the maximum power density of 384.9 $mW/m^2$ which was 5.2 times higher than that obtained from the MFC with SC. Therefore MB and increase of surface area led to enhance the performance of microbial fuel cell such as power density.

Low-area FFT Processor Structure using $Radix-4^2$ Algorithm ($Radix-4^2$알고리즘을 사용한 저면적 FFT 프로세서 구조)

  • Kim, Han-Jin;Jang, Young-Beom
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.49 no.3
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    • pp.8-14
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    • 2012
  • In this paper, a low-area FFT structure using $Radix-4^2$ algorithm is proposed. The large point FFT structure consists of cascade connection of the many stages. In implementation of large point FFT using $Radix-4^2$ algorithm, stages which number of different coefficients are only 3 appear in every 2 stages. For example, in the 4096-point FFT, the stages that number of different coefficients are 3 appear in stage 1, 3, and 5 among 6 stages. Multiplication block area of these 3 stages can be reduced using CSD(Canonic Signed Digit) and common sub-expression sharing techniques. Using the proposed structure, the 256-point FFT is implemented with the Verilog-HDL coding and synthesized by $1.971mm^2$ cell area in tsmc $0.18{\mu}m$CMOS library. This result shows 23% cell area reduction compared with the conventional structure.

Rain Cell Size Distribution Using Radar Data During Squall Line Episodes (레이더 자료를 이용한 강우입자분포의 통계적 분석 연구)

  • Ricardo S. Tenorio;Kwon, Byung-Hyuk;Lee, Dong-In
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.4 no.5
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    • pp.971-976
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    • 2000
  • The main objective of this paper is to present the rain cell size distribution observed during squall line episodes in the Sudano-Sahelian region. The used data were collected during the EPSAT Program [Etude des Precipitation par SATellite (Satellites Study of Precipitation)] which has been developed since 1958, on an experimental area located near Niamey, Niger (2 10′32"E, 13 28′38"N). The data were obtained with a C-band radar and a network composed of approximately 100 raingages over a 10,000 $\textrm{km}^2$. In this work a culling of the squall line episodes was made for the 1992 rainy season. After radar data calibration using the raingage network a number of PPI (Plan Position Indicator) images were generated. Each image was then treated in order to obtain a series of radar reflectivity (Z) maps. To describe the cell distribution, a contouring program was used to analyze the areas with rain rate greater than or equal to the contour threshold (R$\geq$$\tau$). 24700 contours were generated, where each iso-pleth belongs to a predefined threshold. Computing each cell surface and relating its area to an equi-circle (a circle having the same area as the cell), a statistical analysis was made. The results show that the number of rain cells having a given size is an inverse exponential function of the equivalent radius. The average and median equivalent radii ate 1.4 and 0.69 In respectively. Implications of these results for the precipitation estimation using threshold methods are discussed.

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A Case Report of Langerhans Cell Histiocytosis of Frontal Area (전두부에 발생한 랑게르한스세포 조직구증의 치험례)

  • Yang, Hae Won;Kang, Min Gu;Chang, Choong Hyun
    • Archives of Craniofacial Surgery
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    • v.10 no.1
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    • pp.37-39
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    • 2009
  • Purpose: Langerhans cell histiocytosis is a heterogenous group of Langerhans cell proliferative disorders and includes eosinophilic granuloma, Letterer-Siwe diseases, and Hand-Schuller Christian disease. We report a case of eosinophilic granuloma on frontal area. Methods: A 17-year-old male presented with swelling and tenderness on Lt. frontal and periorbital area. CT and MRI showed a $33{\times}25mm$ sized mass that involved Lt. frontal calvarium, frontotemporal meninges, and orbital roof. Results: Total excision of the mass and adjacent soft tissue, calvarium, and orbital roof was performed. Orbital roof defect was reconstructed with absorbable plate and calvarial defect was done with outer cortex of temporal bone flap. The histology revealed proliferation of histiocytes and eosinophils. Immunologically, these histiocytic cells expressed S-100 protein and CD1a. The patient is currently taking conservative treatment. Conclusion: The severity of these disease and their prognosis and treatments are various. For unifocal cranial Langerhans cell histiocytosis, complete excision is the treatment of choice. We report this case with review of literature.

An Analysis of Requisite Knowledge Body of Physiology for Nursing Education (간호학 관점에서 본 생리학 지식체 내용 분석)

  • Seo Wha-Sook
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.2 no.2
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    • pp.229-237
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    • 1995
  • The purpose of this study is to define requisite content of physiology for nursing education. This study classifies the subjects of physiology into 15 areas. The areas are cell and cell membrane, body fluid, nervous system, special sense, muscular system, blood, cardiovascular system, respiratory system, urinary system, digestive system, energy metabolism, body temperature, immune system, endocrine system, and reproductive system. Each subject area is further classified into subarea, resulting in a total of 194 subarea. The importance of each subarea is measured with a 3-point scale using a questionnaire. The subjects of this study were full-time professors teaching nursing in Korean universities. The analysis of the data collected from 68 respondents is as follows. 1. The areas of physiology necessary for nursing education in the order of importance are : body fluid, blood, endocrine, immune system, body temperature, urinary system, respiratory system, digestive system, reproductive system, energy metabolism, nervous system, cardiovascular system, cell and cell membrane, muscular system, and special sense. 2. Depending on the specific areas of nursing(such as pediatric nursing, maternity nursing), the importance of each physiology area may differ. For instance, the most important area for maternity nursing is reproductive physiology, whereas one for the psychiatric nursing is neuro-physiology. 3. The importance of each physiology area does not determine the importance of its subarea. For example, while the importance of cell and cell membrane was relatively very low across the respondents from different areas of nursing science, the importance of such subarea as osmosis, diffusion, and filteration reported by most respondents were high.

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Optimization Method for MEA Performance Considering the Non-Uniformity of Operating Condition in a Large-area Bipolar Plate (대면적 분리판의 운전 환경 불균일성을 고려한 MEA 성능최적화 방법)

  • Kim, Sungmin;Sohn, Young-Jun;Woo, Seunghee;Park, Seok-Hee;Jung, Namgee;Yim, Sung-Dae
    • New & Renewable Energy
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    • v.17 no.2
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    • pp.50-58
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    • 2021
  • We proposed an MEA development methodology that accurately measures intrinsic MEA performance while considering the uneven reaction environments formed inside a large-area BP. To facilitate measurement of the inherent MEA performance, we miniaturized the active area of the MEA to 3 cm2, and prepared two MEAs with different ionomer contents of 0.65 and 0.80 (I/C). By simulating the operating conditions of a 100 cm2 BP at the inlet (I), center (C), and outlet (O), the oxygen concentration and relative humidity were determined to be 20.7, 13.8, 11.7%, and 50, 66.1, and 70.1% respectively. We measured the performance and electrochemical analysis of the prepared MEAs under the three simulated conditions. Based on the results of statistical analysis of the evaluated MEA performance data, I/C 0.65 MEA had a higher average performance and lower performance deviation than I/C 0.80 MEA. Hence, it can be concluded that an I/C 0.65 MEA is a more effective MEA for large-area BP. Based on the above research process, we confirmed the effectiveness of the proposed MEA development methodology.

Fabrication of Large-Area Photovoltaic Crystal with Modified Surface Using Trimethoxysilyl Propyl Methacrylate (TMSPM) for Solar Cell Protection

  • Kang, Kwang-Sun
    • Current Photovoltaic Research
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    • v.2 no.3
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    • pp.84-87
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    • 2014
  • Protection of solar cell surface is important to prevent from dust, pollen, sand, etc. Therefore, development of large area antifouling film is urgent for high performance of solar cells. The surface of silica spheres was modified to fabricate large area antifouling film. The surface of monodisperse silica spheres has been modified with 3-(trimethoxysilyl) propylmethacrylate (TMSPM) to fabricate large area photonic crystal. Although the surface modification of silica spheres with TMSPM has been failed for the base catalyst, the second trial using acid catalyst showed the following results. The FTIR absorption peak at $1721cm^{-1}$ representing C=O stretching vibration indicates that the TMSPM was attached on the surface of silica spheres. The methanol solution comprised of the surface modified silica spheres (average diameter of 380 nm) and a photoinitiator was poured in the patterned silicon wafer with the dimension of 10 cm x 10 cm and irradiated UV-light during the self-assembly process. The result showed large area crack and defect free nanostructures.