• Title/Summary/Keyword: cell

Search Result 62,167, Processing Time 0.069 seconds

A Study on the Stability of High Density SRAM Cell) (고집적 SRAM Cell의 동작안정화에 관한 연구)

  • Choi, Jin-Young
    • Journal of the Korean Institute of Telematics and Electronics A
    • /
    • v.32A no.11
    • /
    • pp.71-78
    • /
    • 1995
  • Based on the popular 4-transistor SRAM cell, an analytical expression of the minimum cell ratio was derived by modeling the static read operation. By analyzing the relatively simple expression for the minimum cell ratio, which was derived assuming the ideal transistor characteristics, effects of the changes in supply voltage and process parameters on the minimum cell ratio was predicted, and the minimum power supply voltage for read operation was determined. The results were verified by simulations utilizing the suggested simulation method, which is suitable for monitoring the lower limit of supply voltage for proper cell operation. From the analysis, it was shown that the worst condition for cell operation is low temperature and low supply voltage, and that the operation margin can be effectively improved by reducing the threshold voltage of the cell transistors.

  • PDF

What is a Cancer Cell? Why does it Metastasize?

  • Hegde, Mahabaleshwar Vishnu;Mali, Aniket Vijay;Chandorkar, Shubha Sandeep
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.6
    • /
    • pp.3987-3989
    • /
    • 2013
  • This is a commentary on what a cancer cell is and why cancer cells metastasize. Normal cell get transformed to a cancer cell, with excessive production of free radicals that mutate the DNA of a normal cell. The immortality and malignant stage of transformed cell is maintained by higher GSH levels. With the faster rate of proliferation, when the cancer cell finds the place of origin is not conducive to its further growth, cancer cell chooses to take the metastatic course. We argue that if we can stop the exit of cancer cell from place of origin, cancer spread can be stopped or even cured.

Metallization of Buired contact Solar cell (BCSC(Buired contact Solar cell)의 전극형성)

  • 김동섭;조영현;이수홍
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 1995.05a
    • /
    • pp.145-149
    • /
    • 1995
  • The metallization is the key to determining cell costs, call performance, and cell and system reliabiltiy. The Burled Contact Solar Cell (BCSC) was specifical1y desinged to be compatible tilth low cost, mass production techniques and avoid the conventional metallization problem. By using electroless plating trchniqeu, we performed this metallization inexpensively and reliabley, This paper presents the details of the optimization procedure of metallization schemes on laser grooved cell surface Commercially available Ni ,Cu, and Ag plating solutions were applied for the cell metallization. The application of those solutions on the buried contact front metalization has resulted in an cell efficiency of 18.5% The cell parameters are an open circuit voltage of 651 mV, short circuit current density of 38.6 mA/$\textrm{cm}^2$, and fill factor of 73.5%.

  • PDF

Cell Cycle and Cancer

  • Park, Moon-Taek;Lee, Su-Jae
    • BMB Reports
    • /
    • v.36 no.1
    • /
    • pp.60-65
    • /
    • 2003
  • Cancer is frequently considered to be a disease of the cell cycle. As such, it is not surprising that the deregulation of the cell cycle is one of the most frequent alterations during tumor development. Cell cycle progression is a highly-ordered and tightly-regulated process that involves multiple checkpoints that assess extracellular growth signals, cell size, and DNA integrity. Cyclin-dependent kinases (CDKs) and their cyclin partners are positive regulators of accelerators that induce cell cycle progression; whereas, cyclin-dependent kinase inhibitors (CKIs) that act as brakes to stop cell cycle progression in response to regulatory signals are important negative regulators. Cancer originates from the abnormal expression of activation of positive regulators and functional suppression of negative regulators. Therefore, understanding the molecular mechanisms of the deregulation of cell cycle progression in cancer can provide important insights into how normal cells become tumorigenic, as well as how cancer treatment strategies can be designed.

An Experimental Study of Short Stack on the Performance of the Proton Exchange Membrane Fuel Cell for the Residential Power generation (소형 모듈 스택을 이용한 가정용 연료전지 성능의 실험적 고찰)

  • Choi, Won-Seok;Kim, Yong-Mo;Yu, Sang-Seok;Lee, Young-Duk;Hong, Dong-Jin;Ahn, Kook-Young
    • 한국신재생에너지학회:학술대회논문집
    • /
    • 2008.05a
    • /
    • pp.21-24
    • /
    • 2008
  • Proton Exchange Membrane Fuel Cell (PEMFC) is an attractive candidate for residential power generator due to fast start-up and stop, high efficiency, low emission, and high power density. In this study, we employ short module stack to understand the performance of the unit cell of the stack in terms of operating temperatures. To simulate the practical fuel cell stack of residential power generator, the structure and active area of the short module stack is kept the same as that of the practical fuel cell. The results shows that the electric potential of short module stack is different from the number of cells times the potential of unit cell because of cell-to-cell variation.

  • PDF

DEVELOPMENT OF FUEL CELL HYBRID ELECTRIC VEHICLE PERFORMANCE SIMULATOR

  • Park, C.;Oh, K.;Kim, D.;Kim, H.
    • International Journal of Automotive Technology
    • /
    • v.5 no.4
    • /
    • pp.287-295
    • /
    • 2004
  • A performance simulator for the fuel cell hybrid electric vehicle (FCHEV) is developed to evaluate the potentials of hybridization for fuel cell electric vehicle. Dynamic models of FCHEV's electric powertrain components such as fuel cell stack, battery, traction motor, DC/DC converter, etc. are obtained by modular approach using MATLAB SIMULINK. In addition, a thermodynamic model of the fuel cell is introduced using bondgraph to investigate the temperature effect on the vehicle performance. It is found from the simulation results that the hybridization of fuel cell electric vehicle (FCEV) provides better hydrogen fuel economy especially in the city driving owing to the braking energy recuperation and relatively high efficiency operation of the fuel cell. It is also found from the thermodynamic simulation of the FCEV that the fuel economy and acceleration performance are affected by the temperature due to the relatively low efficiency and reduced output power of the fuel cell stack at low temperature.

Acupuncture Suppresses Intrastriatal Hemorrhage-Induced Neuronal Cell Death and Proliferation in Rats

  • Cho, Nam-Hun;Park, Dong-suk;Lee, Jae-Dong
    • The Journal of Korean Medicine
    • /
    • v.24 no.4
    • /
    • pp.127-135
    • /
    • 2003
  • Objectives : Intracerebral hemorrhage (ICH) is one of the most devastating types of stroke. The effect of acupuncture on the intrastriatal hemorrhage-induced neuronal cell death and cell proliferation in rats is examined. Methods : Cell death and cell proliferation in rats was investigated via terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay and immunohistochemistry for caspase-3 and 5-bromo-2'-deoxyuridine (BrdU). Results : Results showed that apoptotic cell death in the striatum and cell proliferation in the hippocampal dentate gyrus significantly increased following intrastriatal hemorrhage in rats, and that acupunctural treatment at the Zusanli acupoint suppressed the hemorrhage-induced increase in apoptosis in the striatum and cell proliferation in the dentate gyrus. Conclusions : It is suggested that acupunctural treatment, especially at the Zusanli acupoint, may aid recovery following central nervous system sequelae following ICH.

  • PDF

Histological changes in brain tissue of rat induced neuronal excitotoxicity by NMDA(N-methyl-D-asparate) (NMDA(N-methyl-D-asparate)의 투여에 의해 유발된 신경 과흥분상태에서의 쥐의 뇌조직 변화)

  • Song, Jae-chan
    • Korean Journal of Veterinary Research
    • /
    • v.38 no.2
    • /
    • pp.290-296
    • /
    • 1998
  • Histological changes was investigated in the 4 weeks old rat brain using NMDA (N-methyl-D-asparate) which is capable of mediating excitotoxic events. The changes were occured when the injected NMDA solved in PBS was over $1.0{\mu}g/g$(about 90nM). The necrosis of Purkinje cells in cerebellum and the increasement of coloidal plexus cell number were prevalent. The Purkinje cell number of necrosis were increased according to increasement of amount of injected NMDA. In spite of increasement of degenerated Purkinje cell number, differentiation of new Purkinje cell was not identified because total number of Purkinje cell was not changed. The change of cell number was observed in coloidal plexus cell rather than degeneration of cell. About 5 time increasement was occured. This change may cause increasement of cerebrospinal fluid and the makes mophorogy of brain more round than nomal.

  • PDF