• 제목/요약/키워드: cause of cancer

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Pore Properties of Magnesium Oxide Matrix using Red Mud and Vermiculite (버미큘라이트 및 레드머드를 활용한 산화마그네슘 경화체의 공극 특성)

  • Lim, Hyun-Ung;Lee, Won-Gyu;Lee, Sang-Soo;Song, Ha-Young
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2018.11a
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    • pp.120-121
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    • 2018
  • Radon is one of the substances that pollute the indoor air and is classified as a first-level carcinogen by the International Agency for Research on Cancer(IARC) together with asbestos, and it is reported that it can cause lung cancer. The World Health Organization(WHO) reports that lung cancer is the second leading cause of lung cancer, and 6-15% of lung cancer patients report lung cancer caused by radon. Radon occurs in cracks in concrete and aged buildings, and is detected in soil, rocks, groundwater, and so on. It is a colorless, odorless and tasteless gas which is adsorbed to dust in the air and enters through human respiratory system. This study used vermiculite (expanded vermiculite), which has excellent ion exchange ability and a large number of pores, and industrial by - product red mud which has heavy metal adsorption ability, in order to adsorb radon. A matrix capable of adsorbing radon was prepared, and the characteristics of each material were compared and analyzed.

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Frequency and Type-distribution of Human Papillomavirus from Paraffin-embedded Blocks of High Grade Cervical Intraepithelial Neoplasia Lesions in Thailand

  • Swangvaree, Sukumarn Sanersak;Kongkaew, Phon;Ngamkham, Jarunya
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.2
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    • pp.1023-1026
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    • 2013
  • Cervical cancer is the most important female gynecological cancer, the second leading cause of cancer mortality in women worldwide and the second most common cancer in Thai women. The major cause of cervical cancer is persistent infection of human papillomavirus (HPV), leading to abnormal epithelial lesions, with progression to precancerous and invasive cancer. This study was conducted to investigate the frequency and type distribution of HPV in Thai women who had abnormal cytology. HPV detection from FFPE confirmed abnormal of high grade cervical intraepithelial lesions were for SPF-10-Innogenic Line Probe Assay. HPV-positivity was detected in 320/355 cases (90.14%) and HPV-negativity in 35/355 (9.86%). HPV-positive was found 147/320 cases (41.4%) of single infection, whereas 173/320 cases (48.7%) showed the multiple HPV infection. The most common seven types were HPV-16, -52, -18, -11, -51, -31 and -33, in that order. HPV 16 and 18, the important oncogenic HPV type, were observed in 64.8% of HSIL cases. Interestingly, a high proportion of multiple infections was found in this study and more than ten types could be detected in one case. Therefore, HPV infection screening program in women is essential, particularly in Thailand. Effective primary and secondary prevention campaigns that reinforce HPV screening for HPV detection and typing may be decrease the incidence and mortality of cervical cancer in the future and may lead to significantly improve the quality of life in Thai women.

Clusters Analysis According to Causal Attribution in Patients with Cancer (암환자가 지각한 원인지각 차원별 동질집단 분석)

  • Ryu, Eun-Jung;Choi, So-Young;Choi, Kyung-Sook
    • Asian Oncology Nursing
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    • v.3 no.1
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    • pp.66-74
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    • 2003
  • Purpose: This study is designed to identify clusters according to the causal attribution that people make about the cancer and to determine influences of coping behavior and depression as output of causal attribution. Method: The subjects were 192 patients who had been diagnosed cancer one year ago and attended an outpatient clinic. For cancer patients to be classified homogenious groups according to causal attribution, cluster analysis of subjects' ratings on the Causal Dimension Scale was been made. Results: Cluster 1(n=71) had patients with having external, stable and uncontrollable attribution. Cluster 2(n =70) had patients with having unstable and external controllable attribution regarding cause of cancer. They were not important whether cause of cancer was self or other. Cluster 3(n=51) had patients with having internal, unstable and internal controllable attribution. Coping behaviors between cluster 1 and 3 were significant difference. However, depression was not significant difference among clusters. Conclusion: Based upon these results, it is recommended that the developing training program to be changed to the more positive attribution is necessary.

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Proper Oral Hygiene and Dental Care for Cancer Patients (항암치료를 받는 환자의 구강관리 및 치과 치료)

  • Seung-Joo Nam
    • Journal of Digestive Cancer Research
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    • v.11 no.1
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    • pp.41-44
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    • 2023
  • Oral complications, such as mucositis, infection, or xerostomia, are common in patients with cancer receiving chemotherapy or radiotherapy. These complications can cause pain, leading to increased consumption of analgesics, poor oral intake, malnutrition, and even a need for parenteral nutrition. Moreover, they can sometimes interrupt the treatment plan. This review focuses on the proper management and prevention of oral complications that are common in patients with cancer receiving chemotherapy or radiotherapy.

Association of dietary patterns with overweight risk and all-cause mortality in children with cancer

  • So, Eunjin;Kim, Jeeyeon;Joo, Sehwa;Lee, Jisun;Joung, Hyojee
    • Nutrition Research and Practice
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    • v.11 no.6
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    • pp.492-499
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    • 2017
  • BACKGROUND/OBJECTIVES: This study aimed to investigate the association of dietary patterns with overweight risk and all-cause mortality in pediatric cancer patients. SUBJECTS/METHODS: Prospective cohort study was undertaken; 83 cancer patients admitted to the pediatric cancer ward at a university hospital in Seoul were included and followed for obesity and death over 24 months. Food consumption data were collected from patients using validated meal order sheets for breakfast, lunch, and dinner at the pediatric cancer ward over 3 days. Using principal component analysis, three dietary patterns were derived from 29 food groups. RESULTS: Eighteen deaths occurred among the patient cohort during the follow-up period. The "spicy & fried meat and fish" dietary pattern was positively associated with overweight risk at both baseline [odds ratio (OR) = 4.396, 95% confidence interval (CI) = 1.111-17.385, P for trend = 0.023] and after 6 months (OR = 4.088, 95% CI = 1.122-14.896, P for trend = 0.025) as well as all-cause mortality (hazard ratios = 5.124, 95% CI = 1.080-24.320, P for trend = 0.042), when comparing the highest and lowest tertiles after adjusting for covariates. The "fish, egg, meat, and fruits & vegetables" dietary pattern was associated with lower overweight risk after 24 months (OR = 0.157, 95% CI = 0.046-0.982, P for trend = 0.084). CONCLUSION: The results imply that dietary patterns might be associated with weight gain and premature death among pediatric cancer patients.

Mortality of Major Cancers in Guangxi, China: Sex, Age and Geographical Differences from 1971 and 2005

  • Deng, Wei;Long, Long;Li, Ji-Lin;Zheng, Dan;Yu, Jia-Hua;Zhang, Chun-Yan;Li, Ke-Zhi;Liu, Hai-Zhou;Huang, Tian-Ren
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.4
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    • pp.1567-1574
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    • 2014
  • The incidence and mortality rates of liver and nasopharyngeal cancer in Guangxi province of China have always been among the highest in the world, and cancer is one of the major diseases that pose a threat to the health of residents in Guangxi. However, no systematic study has been performed to evaluate the time trends in the structure of cancer-related deaths and cancer mortality. In this study, we reveal sex, age and geography differences of cancers mortality between three death surveys (1971 to 1973, 1990 to 1992, and 2004 to 2005). The results show that the standardized mortality rate of cancer in Guangxi residents has risen from 43.3/100,000 to 84.2/100,000, the share of cancer deaths in all-cause deaths has increased from 13.3% to 20.7%, and cancer has become the second most common cause of death. The five major cancers, liver cancer, lung cancer, gastric cancer, nasopharyngeal cancer and colorectal cancer, account for 60% of all the cancer deaths. Cancers with growing mortality rates over the past 30 years include lung cancer, colorectal cancer, liver cancer and female breast cancer, of which lung cancer is associated with the sharpest rise in mortality, with a more than 600% rise in both men and women. Cancer death in Guangxi residents occurs mainly in the elderly population above 45 years of age, especially in people over the age of 65. The areas with the highest mortality rates for liver cancer and nasopharyngeal cancer, which feature regional high incidences, include Chongzuo and Wuzhou. Therefore, for major cancers such as liver cancer, lung cancer, gastric cancer, nasopharyngeal cancer and female breast cancer in Guangxi, we can select high-risk age groups as the target population for cancer prevention and control efforts in high-prevalence areas in a bid to achieve the ultimate goal of lowering cancer mortality in Guangxi.

Importance of Early Diagnosis and Screening, Lessons from Gastric Cancer and Colorectal Cancer

  • Seun Ja Park
    • Journal of Digestive Cancer Research
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    • v.2 no.1
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    • pp.5-7
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    • 2014
  • Screening and early diagnosis of cancer is important. Screening lead to detect disease earlier, and earlier treatment of disease cause to yield a better outcome than treatment at the onset of symptoms. Some studies suggest that gastric cancer screening may be associated with a reduced risk of mortality from gastric cancer, although there are no definitive data from large controlled trials. Regular colorectal cancer screening or testing is one of the most powerful weapons for preventing colorectal cancer, because some polyps, or growths can be found and removed before they have the chance to turn into cancer. Screening can also result in finding colorectal cancer early, when it is highly curable. In conclusion, to increase utilization of screening is important to decrease gastric and colorectal cancer morbidity and mortality.

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Positive and Negative Effects of IT on Cancer Registries

  • Mohammadzadeh, Niloofar;Safdari, Reza;Rahimi, Azin
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.7
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    • pp.4455-4457
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    • 2013
  • In the new millennium people are facing serious challenges in health care, especially with increasing non-communicable diseases (NCD). One of the most common NCDs is cancer which is the leading cause of death in developed countries and in developing countries is the second cause of death after heart diseases. Cancer registry can make possible the analysis, comparison and development of national and international cancer strategies and planning. Information technology has a vital role in quality improvement and facility of cancer registries. With the use of IT, in addition to gaining general benefits such as monitoring rates of cancer incidence and identifying planning priorities we can also gain specific advantages such as collecting information for a lifetime, creating tele medical records, possibility of access to information by patient, patient empowerment, and decreasing medical errors. In spite of the powerful role of IT, we confront various challenges such as general problems, like privacy of the patient, and specific problems, including possibility of violating patients rights through misrepresentation, omission of human relationships, and decrease in face to face communication between doctors and patients. By implementing appropriate strategies, such as identifying authentication levels, controlling approaches, coding data, and considering technical and content standards, we can optimize the use of IT. The aim of this paper is to emphasize the need for identifying positive and negative effects of modern IT on cancer registry in general and specific aspects as an approach to cancer care management.

Risk Factors for Lung Cancer Mortality in a Referral Center

  • Jamaati, H;Baghaei, P;Sharifianfard, M;Emami, H;Najmi, K;Seifi, S;Salimi, B;Pourabdollah, M;Kiani, A;Hashemian, M;Khosravi, A
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.6
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    • pp.2877-2881
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    • 2016
  • Background: Lung cancer is one of the most common causes of death that is rising in many countries including Iran. This study aimed to determine the impact of factors on survival of lung cancer patients at a referral center of lung diseases in Tehran, Iran. Materials and Methods: A retrospective study was conducted on adult lung cancer cases admitted to a referral center for lung diseases from 2011 to 2015. Multivariate analysis was performed to determine the risk factors for all-cause mortality. Results: Of a total 933 patients with lung cancer, 53.4% died, 49.3% of them at the hospital. Overall median follow-up time was 7 months. The most common histological type of cancer was adenocarcinoma with a 13 month median survival time. Age ${\geq}55$ and smoking remained significant for all-cause mortality on Cox analysis, whereas gender was not. Conclusions: The survival of lung cancer patients is poor and the patients with history of smoking and age${\geq}55$ are at increased risk of death. Having a large hospital-based registry provides a good measurement of prognostic statistics for lung cancer. Further investigations are necessary to establish reasons for mortality.

Update of Adjuvant Chemotherapy for Resected Gastric Cancer

  • Oh, Sang-Cheul
    • Journal of Gastric Cancer
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    • v.12 no.1
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    • pp.3-6
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    • 2012
  • Gastric cancer is the second cause of cancer that is related to death and the fourth most common cancer, worldwide. Complete resection of cancer is the only curative treatment for gastric cancer. However, even if complete resection is possible, recurrence is frequently observed in Gastric patients. Therefore, adjuvant treatment modality for resectable gastric cancer is needed to increase the survival of patients. This study wants to describe the role of adjuvant chemotherapy for resectable gastric cancer, with updated data of recent studies. Several meta-analysis studies demonstrated a benefit of adjuvant chemotherapy for resectable gastric cancer. Due to the heterogeneity of the population and regimens, there is no consensus regarding the adjuvant chemotherapy. Recently published, well designed phase III studies demonstrated the statistically significance of adjuvant chemotherapy for the resectable gastric cancer, with the extended lymph node dissection. Further phase III trials, to determine the best regimen and schedule of adjuvant chemotherapy, was suggested to use the fluoropyrimidine based regimen as control group.