• 한국정밀공학회지
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• 제24권6호
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• pp.66-71
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• 2007

Development of a locomotive mechanism for the capsule type endoscopes will largely enhance their ability to diagnose disease of digestive organs. As a part of it, there should be provided a detection device of their position in human organs for the purpose of observation and motion control. In this paper, a permanent magnet outside human body was employed to project magnetic field on a capsule type endoscope, while its position dependent flux density was measured by three hall-effect sensors which were orthogonally installed inside the capsule. In order to detect the 2-D position data of the capsule with three hall-effect sensors including the roll, pitch and yaw angle, the permanent magnet was extra translated during the measurement. In this way, the 2-D coordinates and three rotation angles of a capsule endoscope on the same motion plane with the permanent magnet could be detected. The working principle and performance test results of the capsule position detection device were introduced in this paper showing that they could be also applied to 6-DOF position detection.

• Korean Journal of Hydrosciences
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• 제5권
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• pp.115-124
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• 1994

This paper presents the results of a study conducted to improve the understanding of the characteristics of cylindrical capsule flow in a pipeline by taking into account of the effect of capsule density uniformity. The effect fo capsule density variation in the axial direction was studied both experimentally and analytically. The experiments were conducted in a 190mm diameter straight pipe 17m long. The velocity, gap and tilt of capsules were measured under various conditions. In order to interpret the data on various capsule density conditions, the stability index given in the dimensionless number was introduced. The motion of capsules in pipelines is strongly affected by the stability of the capsules characterized by the statility index. The experiments conducted proved that the stability index is a vaild criterion for explaining and correlating data on the capsule motion and the capsule denisity uniformity.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2005년도 춘계학술발표회
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• pp.395-396
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• 2005

• Fisheries and Aquatic Sciences
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• 제2권1호
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• pp.44-51
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• 1999

Proteolytic bacteria isolated from fermented anchovy jeotkal were immobilized in capsule type with $0.8\%$ sodium alginate and $CaCl_2/carboxymethyl$ cellulose (CMC). For making the immobilized capsule, the optimal concentration of both $CaCl_2$ and CMC, with respect to the membrane hardness and the growth of proteolytic bacteria in capsule, were $2.0\%$ at following conditions: flow rate of $CaCl_2/CMC$ solution and cell suspension were respectively 3.54 ml/min and 0.15 ml/min when inside diameter of inner and outer capillary tube in immobilizing apparatus were 0.32mm, 0.74mm, respectively. The density of proteolytic bacteria in capsule reached maximum, i.e. $10^8-10^9cells$/capsule during culture under optimal conditions in TPY broth, and these were $10^2-10^4$ times higher than these of before culture. During culture of proteolytic bacteria immobilized in capsule type (PBImC) for 72hrs, few growing cells were lost in the outer medium.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 1993년도 수공학연구발표회논문집
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• pp.483-490
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• 1993

본 논문은 캡슐밀도의 균일성의 영향을 고려하여 관로내에서의 원통형 캡슐 흐름의 특성을 이해하기 위하여 수행된 연구결과를 기술한다. 캡슐의 중심 축방향으로의 밀도변화 영향을 실험적으로나 분석적인 방법으로 연구하였다. 실험은 직경 190mm, 길이 18m인 관에서 수행되었으며, 속도, 캡슐의 기울기, 캡슐바닥과 관과 간격이 여러가지 실험조건하에서 측정되었다. 실험데이타를 해석하기 위하여 무차원 변수로 주어지는 안정성지수(Stability Index)가 유도되었다. 관로에서의 캡슐의 거동은 안정성지수에 크게 영향을 받는다. 실험결과는 안정성지수가 캡슐거동과 캡슐밀도의 균일성과의 상관관계를 잘 설명하여주는 유효한 기준임을 증명하였다.

• 대한기계학회논문집A
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• 제28권8호
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• pp.1166-1173
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• 2004

In this paper, in order to apply magnetic fluid with superparamagnetic property as the substitute of ferromagnetic materials, physical properties of magnetic fluid are investigated. A targeted drug delivery system using a capsule filled magnetic fluid is proposed where a magnetic fluid capsule and cylinders are considered as a drug and vital organs, respectively. The dynamic governing equation of this system first is derived. Fluid viscosity, clearance between a cylinder and a magnetic fluid capsule, and levitation height with respect to different cylinder height are considered as major parameters to evaluate dynamic characteristics of the system. The experiments and simulations for the position control of the magnetic fluid capsule in various cylinders are conducted using PID controller. The results show that magnetic fluid with the superparamagnetic property can be applied to a targeted drug delivery system.

• 한국컴퓨터정보학회논문지
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• 제21권12호
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• pp.125-130
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• 2016

Automatic quality inspection by computer vision can be applied and give a solution to the pharmaceutical industry field. Pharmaceutical capsule can be easily affected by flaws like dents, cracks, holes, etc. In order to solve the quality inspection problem, it is required computationally efficient image processing technique like thresholding, boundary edge detection and segmentation and some automated systems are available but they are very expensive to use. In this paper, we have developed a dented capsule image processing technique using edge-based image segmentation, TLS(Total Least Squares) curve fitting technique and adopted low cost camera module for capsule image capturing. We have tested and evaluated the accuracy, training and testing time of the classification recognition algorithms like PCA(Principal Component Analysis), ICA(Independent Component Analysis) and SVM(Support Vector Machine) to show the performance. With the result, PCA, ICA has low accuracy, but SVM has good accuracy to use for classifying the dented capsule.

• 한국가시화정보학회지
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• 제17권1호
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• pp.19-25
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• 2019

We report a study on the dynamics of the transport of a capsule immersed in a vertical pipe. Techniques to convey objects through liquid flow pipes using a hydraulic mean are used to transport sludge and hazardous materials. For the better understanding of the techniques, we developed a theoretical model to predict the transport speed of a cylindrical capsule in a vertical pipe. The comparison of the model prediction with the experiments shows that our model using the lubrication approximation precisely describes the experimental observations in cases where the gap between the capsule and pipe wall is sufficiently small. Our study suggests parameters to control the falling speed and thus enable an accurate control of the capsule speed in hydraulic transport systems.

• 한국작물학회지
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• 제30권2호
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• pp.158-164
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• 1985

참깨 후기등숙 불량을 개성하기 위한 기초연구로서 각 초형별 삭과와 종실의 상육과정을 조사·비교한 결과 다음과 같은 결론을 얻었다. 1. 삭장은 수정 직후부터 신장을 시작하여 수정후 35 일에 최대를 기록한 후 점차 감소하였다. 2. 상위삭의 삭장은 중·하위등에 비하여 짧아 발육이 부진하였으며, 4실8방 형은 2실4방 형보다 상위삭의 발육이 더욱 불량하였으나 BTB (분지, 3,2/4) 형은 타 초형에 비하여 상위삭의 발육이 양호한 편이었다. 3. 삭의 착생 위치에 따른 발육은 주경 중심삭>분지 중심삭 >주경 측삭 >분지 측삭의 순으로 좋았다. 4. 삭폭은 삭장에서와 같이 수정 후 35 일에 최대를 기록하다가 이 시기를 정점으로 점차 감소하였으며 삭의 발육은 착삭 하위부>중위부>상위부의 순으로 양호하였다. 5. 3과성 4실 8방형에서는 상위삭폭이 생식생장 후기에 큰 폭으로 떨어져 등숙면에서 불리하였으며 삭장에서와 같은 경향이었다. 6. 생체 천립중에서도 수정 후 35 일에 최대를 기록한 후 점차 감소하는 경향이었으며 착삭 하위부>중위부>상위부의 순으로 발육이 양호하였다. 7. 천립중에서도 분지삭과 측삭은 중심삭보다도 발육이 떨어졌으며 4실8방 형은 삭폭이나 삭장에서와같이 생식생장 후기 상위삭의 천립중 감소가 심하였다. 8. BTB(분지, 3,2/4) 형은 가장 많은 sink를 보유하였음에도 중·하위부삭에 대비한 상위부삭의 천립중 감소가 많지 않아 등숙과 증수 측면에서 유리하였으며 수량성을 극대화하기 위해서는 BTB와 같은 초형에 분지삭과 측삭의 충실도를 높이는 방향의 육종이 바람직하다 하겠다.

• Clinical Endoscopy
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• 제51권6호
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• pp.570-575
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• 2018

Background/Aims: Capsule endoscopy is a diagnostic method for evaluating the small bowel lumen and can detect undiagnosed lesions. The aim of this study was to evaluate the diagnostic yield and clinical impact of capsule endoscopy in patients with refractory diarrhea-predominant irritable bowel syndrome and functional abdominal pain. Methods: This study involved a retrospective analysis of prospectively collected data, maintained in a database. Patients with refractory diarrhea-predominant irritable bowel syndrome and functional abdominal pain within the period of March 2012 to March 2014 were included. Capsule endoscopy was used to detect small bowel pathologies in both groups. Results: Sixty-five patients (53.8% female) fulfilled the inclusion criteria and had a mean (${\pm}$standard deviation) age of $50.9{\pm}15.9$ years. Clinically significant lesions were detected via capsule endoscopy in 32.5% of the patients in the abdominal pain group and 54.5% of the patients in the diarrhea group. Overall, 48% of patients had small bowel pathologies detected during the capsule endoscopy study. Inflammatory lesions and villous atrophy were the most frequent lesions identified in 16.9% and 15.3% of patients in the abdominal pain and the diarrhea groups, respectively. Conclusions: Routine use of capsule endoscopy in patients with irritable bowel syndrome should not be recommended. However, in patients with refractory conditions, capsule endoscopy may identify abnormalities.