• Korean Journal of Acupuncture
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• 제29권4호
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• pp.623-633
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• 2012

Objectives : Fatigue is a common and distressing symptom that is a concern for cancer patients. It has a decisive effect on quality of life. The purpose of this study was to examine the feasibility of clinical trial to evaluate of efficacy and safety of acupuncture on cancer related fatigue of lung cancer patients. Methods : Total lung cancer 9 patients complained of fatigue were treated by acupuncture twice a week for four weeks(8 times in total). Evaluation of the severity of fatigue was measured by FSS(Fatigue Severity Score). In visit 1, 10, we checked FSS. For check safety of acupuncture treatment, we did blood test. Results : After 4 weeks of acupuncture treatment, the FSS was significantly decreased from $4.92{\pm}1.06$ to $3.74{\pm}1.37$(p=0.008). And the level of hemoglobin was significantly increased from 10.87 g/dl to 12.01 g/dl(p=0.014). No other lab measures indicated any significant differences between before and after acupuncture treatment. Conclusions : This study suggests that acupuncture treatment will be beneficial for lung cancer patients to improve the fatigue severity. And acupuncture treatment is safe method for lung cancer patients. A large-scale study to confirm efficacy and safety of acupuncture is needed.

• 임상간호연구
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• 제17권2호
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• pp.163-175
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• 2011

Purpose: This study was to analyze the characteristics and effect size of intervention studies applied to cancer-related fatigue in Korea. Methods: For meta-analysis, a total of 963 studies were retrieved from search engines. And 19 studies with a total of 721 participants published from 1990 to 2010 were selected upon their satisfaction with the inclusion criteria. Two authors independently extracted data from the selected studies and assessed the methodological quality. The data was analyzed by the RevMan 5.0 program of Cochrane library. Results: Intervention studies included 4 studies on foot-reflexo-massage (21.1%), comprehensive program (21.1%), and exercise (21.1%), respectively, 3 for hand-reflexo-massage (15.8%), and 4 for others. The effect size of the intervention studies shown higher effect size in order of exercise (d=-1.80), and foot & hand-reflexo-massage (d=-0.55). Conclusion: This study suggest that exercise can reduce the intensity of cancer-related fatigue, even though the number of intervention studies and randomized controlled trials were very few. There is limited evidence that reflexo-massage is effective in reducing cancer-related fatigue.

• 수면정신생리
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• 제16권1호
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• pp.10-15
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• 2009

Sleep problems and disorders are common in patients with cancer. Sleep of the cancer patients is affected by various factors, including thermoregulatory changes associated with chemotherapy and radiotherapy, cancer related symptoms, such as pain, fatigue, and emotional difficulties. As one of the most common symptoms in cancer patients, fatigue is positively correlated with sleep difficulties. Cytokine is also frequently associated with chemotherapy and radiotherapy. It provokes excessive daytime sleepiness and hypersomnia. Medications for controlling pain, depression, and anxiety can affect sleep of the cancer patients. Medications as well as behavior therapy are reported to be effective for controlling sleep problems, and the physicians need to be accustomed to use the modalities appropriately. This paper reviews causative factors, evaluation, and management of sleep problems and disorders, experienced by cancer patients.

• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.2909-2913
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• 2013

Background: The aim of this study was to determine factors affecting sleep quality of 100 patients with advanced stage lung cancer. Methods and Results: it was a descriptive study. A variety of assessment tools were used to provide sleep scores to examine the relation between adverse effects caused by the treatment (nausea, vomiting, fatigue) and sleep quality. As a result, no statistically significant relation between coughing and respiratory problems of patients, or existing depression, and average sleep quality score was found (KW:0.872, p=0.646, KW: 3.174, p=0.205, u: 441.000 p=0.916). It was revealed that nausea and loss of appetite experienced also did not affect the sleep quality score (p>0.05), whereas problems such as vomiting and fatigue did exert effects (p<0.01). Conclusions: Patients with advanced stage lung cancer suffer from sleep problems and cancer related symptoms also affect their sleep quality negatively. Nurses should plan interventions that can control symptoms such as pain, vomiting and fatigue, which affect the sleep of patients.

• 대한간호학회지
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• 제36권7호
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• pp.1224-1231
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• 2006

Purpose: This study was conducted to identify comprehensive predictors of fatigue in cancer patients. Methods: One hundred ten cancer patients visiting in-patient or out-patient clinics of a university hospital located in Incheon participated in this study. Results: The hematologic indicators (WBC and Hemoglobin) were significant fo. explaining fatigue. The psychological factors of fatigue were statistically significant. Both anxiety and depression, included as psychological factors, were significant in explaining fatigue in cancer patients. The influence of physical factors on fatigue was also statistically significant. Among the variables included as physical factors, pain, nausea/vomiting/anorexia, and sleep disturbance were significant whereas, dyspnea was not significant. The influence of the daily activity factor on fatigue was statistically significant. Among the variables included as daily activity factors, regular exercise or not and the usual activity level were significant in explaining fatigue of cancer patients, while the level of rest was not statistically significant. Conclusions: From the study results fatigue of cancer patients appeared to be influenced by multidimensional factors, such as physiological, physical, psychological, and activity related factors.

• 종양간호연구
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• 제1권1호
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• pp.54-64
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• 2001

This study was conducted to explore the trajectory of fatigue and related factors on people with lung cancer during chemotherapy. A total of 23 patients with lung cancer participated in the beginning stage of the study. However, 11 dropped out because of death or discontinuity of the studys regimens. The data using the Pipers Fatigue Scale, were collected twice the first day of each treatment cycle and the last day of the completion of 6 cycles. Also, the scores of fatigue using the Visual Analogue Scale (VAS) were measured on the same day of each week during chemotherapy to explain the trajectory of fatigue. The data obtained were analyzed using the Wilcoxon signed ranks tests and Kendalls tau b correlation coefficient. The score of fatigue increased in the first two weeks after the administration of chemotherapy, while decreasing after the second week. During the 1st, 5th, and 6th cycles, the scores of fatigue were greater than 5.5 out of 10. Overall, except for the 6th cycle, the score of fatigue was the highest in the first week. This could be accounted for there only being a small number of patients included in the 6th cycle. In conclusion, fatigue was severe at the end of the first week of chemotherapy, and then increased to reach a plateau in the fifth and sixth stages. The results of this study will help oncology nurses to understand the process of fatigue during chemotherapy. It will be useful to create various intervention programs to decrease fatigue in people with cancer especially in the first week of the chemotherapy.

• 한국간호교육학회지
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• 제9권2호
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• pp.244-252
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• 2003

This study was intented to identify the differences of fatigue and quality of life in patients with breast cancer according to the different treatment modalities. Ninety-one subjects were recruited from a medical unit and a therapeutic radiologic clinic at a university hospital in Chungnam, Korea. Fatigue was measured using Lee's scale(1999) translated from Piper's Fatigue Scale and quality of life was measured using Yang's scale(2002). The women with breast cancer receiving chemotherapy were less fatigued and had better quality of life than those receiving radiotherapy(t=-2.914, p=.005; t=2.565, p=.012, respectively). The fatigue and quality of life in the women with breast cancer undergoing cancer treatments were influenced by the weight change during the past 3 months(F=24.70, p=.039). Cancer stage, metastasis and weight were not associated with fatigue and quality of life. Health professionals can help cancer patients undergoing treatments prepare to cope with the expected side effects by providing a specific treatment-related information to them. The findings of this study can contribute the knowledge of these information.

• 기본간호학회지
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• 제22권4호
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• pp.387-397
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• 2015

Purpose: This study aimed to evaluate nutritional status and fatigue, and to identify the relationship between nutritional status and fatigue in gynecological cancer patients receiving chemotherapy. Methods: Participants were 106 outpatients who had uterine, ovary, or breast cancer and a descriptive cross-sectional design was used. Nutritional indicators including biochemical and anthropometric measures, the Subjective Global Assessment (SGA) scale, and the Piper's Revised Fatigue Scale were completed. Results: About thirty-nine percent of the patients were malnourished based on the SGA. Serum hemoglobin and total lymphocyte levels were less than the normal ranges, although anthropometrics were normal. The women experienced moderate fatigue with a mean score of $5.84{\pm}2.00$. Nutritional status was significantly different by age, education, employment status, and monthly income. The women also had different nutritional status and fatigue depending on the type of cancer and chemotherapy. Fatigue was significantly related to SGA scores, serum hemoglobin, triceps skinfold thickness and mid-arm muscle circumference. Conclusion: The results of this study highlight an urgent need to provide adequate nutritional support and fatigue management with individualized strategies for gynecological cancer patients on chemotherapy.

• 대한간호학회지
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• 제42권1호
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• pp.95-104
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• 2012

Purpose: The purpose of this study was to identify the effects of a home based exercise program for patients with stomach cancer who were undergoing oral chemotherapy. Methods: The home-based exercise program was developed from the study findings of Winningham (1990) and data from the Korea Athletic Promotion Association (2007). The home-based exercise program consisted of 8 weeks of individual exercise education and exercise adherence strategy. Participants were 24 patients with stomach cancer who were undergoing oral chemotherapy following surgery in 2007 or 2008 at a university hospital in Seoul. Patients were randomly assigned to either the experimental group (11) or control group (13). The effects of the homebased exercise program were measured by level of cancer related fatigue, NK cell ratio, anxiety, and quality of life. Data were analyzed using SPSS/WIN 13.0 version. Results: The degree of cancer related fatigue and anxiety in the experimental group decreased compared to the control group. The NK cell ratio and the degree of quality of life of experimental group increased while that of the control group decreased. Conclusion: This study result indicate the importance of exercise and provide empirical evidence for continuation of safe exercise for patients with cancer during their chemotherapy.

• 성인간호학회지
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• 제17권2호
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• pp.310-319
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• 2005

Purpose: The purpose of the study is to investigate the degree of fatigue and its related factors in patients with breast cancer. Method: The subjects of this study consisted of 62 breast cancer patients receiving chemotherapy. The Revised Piper Fatigue Scale, Disruption of Usual Activity Scale, Linear Analogue Self Assessment Scale and Self-Care Diary Scale were employed to measure fatigue, disruption of usual activity, mood state and physical symptom respectively. Collected data were analyzed using SPSS-PC to obtain summary statistics for the descriptive analysis, Pearson Correlation, and Stepwise Multiple Regression. Result: The results are as follows. 1. The mean score of the degree of fatigue was 4.82 points indicating moderate level. 2. The mean score of the degree of disruption of usual activity, mood state and physical symptom were 2.66, 5.00, and 4.69 points. 3. Fatigue of the subjects was significantly correlated with disruption of usual activity(r=.517, p<.01), mood state(r=.420, p<.01) and physical symptom(r=.463, p<.01). 4. With the result of stepwise multiple regression, disruption of usual activity, mood state and physical symptom being the three variables which could explain fatigue by 39.1%. The results of this study suggest that comprehensive intervention strategy for fatigue should be developed to maintain quality of life during and following chemotherapy considering these factors.