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Artificial Cultivation and Antioxidant Activity of Korean Native Mushroom Pycnoporus coccineus (한국산 간버섯의 인공재배 및 항산화 활성 평가)

  • Lee, Y.K.;Kim, M.K.;Yun, B.S.;Seo, G.S.
    • Journal of Practical Agriculture & Fisheries Research
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    • v.21 no.2
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    • pp.35-47
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    • 2019
  • The mycelial growth of P. coccineus strain was good in PDA and YMA, but mycelial growth was low in MEA. Light irradiation during the incubation period affected the pigment formation and density of mycelia. Mushroom of P. coccineus strain was able to produce fruiting bodies in both bottle and bag cultivation, and oak sawdust was found to be the most suitable substrate for spawn culture and cultivation. In artificial cultivation using sawdust medium, fruiting body was grown to the extent that visual observation was possible from the 15th day, and it formed about 5 days fast in the treatment group with low relative humidity. From 40 to 45 days of mushroom development, mature fruiting bodies could be harvested, and the lower relative humidity of the growing room favored mushroom development and growth. Antioxidant activity of fruiting bodies harvested from artificial cultivation showed that ABTS radical scavenging activity of bottle-cultivated and wild fruit bodies were shown at 505㎍/㎖ and 515㎍/㎖, respectively. However, fruiting bodies harvested in bag cultivation were high at 910㎍/㎖. As a result of DPPH radical scavenging activity, all extracts were found to be inactive, exhibiting IC50 value of more than 2,000㎍/㎖ concentration. The ethyl acetate extract of mushrooms obtained from bottle cultivation showed the highest activity with 1,550㎍/㎖ IC50 value. Methanol extract of wild fruit bodies had the highest ABTS radical scavenging activity at the same concentration (10mg/㎖).

The Development of a Non-Face-to-Face Instructional Design Model based on Digital Technology for Public Servants (국가공무원을 위한 디지털 기반 비대면 교수설계모델 개발 )

  • Youngeun Wee;Sungil Lee;Jiyoung Lee;Woocheol Kim
    • Journal of Practical Engineering Education
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    • v.15 no.3
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    • pp.557-570
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    • 2023
  • The purpose of this study is to develop a digital-based non-face-to-face instructional design model for national public servants. For this purpose, we reviewed the direction of non-face-to-face instructional design based on previous research, and interviewed a total of 10 instructors and learners with experience in non-face-to-face education to identify the success factors of non-face-to-face instructional design for government employees. In addition, to ensure the validity of the instructional design model, a Delphi survey was conducted with experts in instructional design and educational management. As a result, the digital-based instructional design model for national public servants reflects the importance of learning objectives and content design to enhance learning motivation and improve educational effectiveness, and includes detailed implementation plans to support specific and clear performance activities for instructors in non-face-to-face education situations. The instructional design model developed through this study can be expanded as a standard for improving the quality of education in public human resource development, and can be used as a teaching and learning guide according to learner types and characteristics.

A Study on the Performance of Vocational Training Course for the New Middle at Korea Polytechnics (2018-2020) (한국폴리텍대학 신중년 직업훈련과정(2018-2020) 성과 연구)

  • Mi-hyun Paek;Ji-young Lee
    • Journal of Practical Engineering Education
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    • v.15 no.3
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    • pp.751-759
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    • 2023
  • In the era of global aging and the retirement of baby boomers, the response is very intensive and dynamic. As baby boomers actually retire, the terms for middle-aged people have been diversified into middle-aged, midle-elderly, and the new middle, which are also evident in the training process. In line with the timing, the government and academia are also making efforts to advance the development of training courses for middle-aged, along with organizing terms for middle-aged. From this point of view, this study aims to analyze the performance of the three-year training courses (2018-2020) for the new middle at Korea Polytechnics and suggest the direction of development of the new middle training course. As a result of the study, the three-year performance of the Shin middle-aged training course gradually increased, but the completion rate and employment rate gradually decreased, indicating that countermeasures were needed. In addition, campus performance in the metropolitan area was higher than that in the non-capital area, so a plan for this deviation was needed. In addition, the need for the integrated operation of the existing 'middle-aged' and 'the new middle' courses operated by Korea Polytechnics was suggested, and measures to specialize in the new middle-aged were proposed.

The Study for EV Charging Infrastructure connected with Microgrid (마이크로그리드와 연계된 전기자동차 충전인프라에 관한 연구)

  • Hun Shim
    • Journal of Internet of Things and Convergence
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    • v.10 no.1
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    • pp.1-6
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    • 2024
  • In order to increase the use of electric vehicles (EVs) and minimize grid strain, microgrid using renewable energy must take an important role. Microgrid may use fossil fuels such as small diesel power, but in many cases, they can be supplied with energy from renewable energy, which is an eco-friendly energy source. However, renewable energy such as solar and wind power have variable output characteristics. Therefore, in order to meet the charging and discharging energy demands of electric vehicles and at the same time supply load power stably, it is necessary to review the configuration of electric vehicle charging infrastructure that utilizes diesel power or electric vehicle-to-grid (V2G) as a parallel energy source in the microgrid. Against this background, this study modelized a microgrid that can stably supply power to loads using solar power, wind power, diesel power, and V2G. The proposed microgrid uses solar power and wind power generation as the primary supply energy source to respond to power demand, and determines the operation type of the load's electric vehicles and the rotation speed of the load synchronous machine to provide stable power from diesel power for insufficient generations. In order to verify the system performance of the proposed model, we studied the stable operation plan of the microgrid by simulating it with MATLAB /Simulink.

Study of MongoDB Architecture by Data Complexity for Big Data Analysis System (빅데이터 분석 시스템 구현을 위한 데이터 구조의 복잡성에 따른 MongoDB 환경 구성 연구)

  • Hyeopgeon Lee;Young-Woon Kim;Jin-Woo Lee;Seong Hyun Lee
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.16 no.5
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    • pp.354-361
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    • 2023
  • Big data analysis systems apply NoSQL databases like MongoDB to store, process, and analyze diverse forms of large-scale data. MongoDB offers scalability and fast data processing speeds through distributed processing and data replication, depending on its configuration. This paper investigates the suitable MongoDB environment configurations for implementing big data analysis systems. For performance evaluation, we configured both single-node and multi-node environments. In the multi-node setup, we expanded the number of data nodes from two to three and measured the performance in each environment. According to the analysis, the processing speeds for complex data structures with three or more dimensions are approximately 5.75% faster in the single-node environment compared to an environment with two data nodes. However, a setting with three data nodes processes data about 25.15% faster than the single-node environment. On the other hand, for simple one-dimensional data structures, the multi-node environment processes data approximately 28.63% faster than the single-node environment. Further research is needed to practically validate these findings with diverse data structures and large volumes of data.

Analysis of Runoff Reduction Effect of Flood Mitigation Policies based on Cost-Benefit Perspective (비용-편익을 고려한 홍수 대응 정책의 유출 저감 효과 분석)

  • Jee, Hee Won;Kim, Hyeonju;Seo, Seung Beom
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.43 no.6
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    • pp.721-733
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    • 2023
  • As the frequency of extreme rainfall events increase due to climate change, climate change adaptation measures have been proposed by the central and local governments. In order to reduce flood damage in urban areas, various flood response policies, such as low impact development techniques and enhancement of the capacity of rainwater drainage networks, have been proposed. When these policies are established, regional characteristics and policy-effectiveness from the cost-benefit perspective must be considered for the flood mitigation measures. In this study, capacity enhancement of rainwater pipe networks and low impact development techniques including green roof and permeable pavement techniques are selected. And the flood reduction effect of the target watershed, Gwanak campus of Seoul National University, was analyzed using SWMM model which is an urban runoff simulation model. In addition, along with the quantified urban flooding reduction outputs, construction and operation costs for various policy scenarios were calculated so that cost-benefit analyses were conducted to analyze the effectiveness of the applied policy scenarios. As a result of cost-benefit analysis, a policy that adopts both permeable pavement and rainwater pipe expansion was selected as the best cost-effective scenario for flood mitigation. The research methodology, proposed in this study, is expected to be utilized for decision-making in the planning stage for flood mitigation measures for each region.

Evaluation of Harmless Crack Size of SCM822H Steel by Double Shot Peening (이중 쇼트 피닝에 의한 SCM822H 강의 무해화 균열 크기 평가)

  • Jin-Woo Choi;Seo-Hyun Yun;Yung-Kug Kwon;Gum-Hwa Lee;Ki-Woo, Nam
    • Journal of the Korean Society of Industry Convergence
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    • v.26 no.6_2
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    • pp.1011-1017
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    • 2023
  • In this study, the harmless crack size (ahml) by double shot peening (DSP) using shot balls with different diameters was evaluated on carburized, quenched-tempered SCM822H steel. The minimum crack size (aNDI) detectable by non-destructive inspection was also evaluated. The relationship between the crack size (a25,50) that reduces the fatigue limit by 25% and 50% and ahml was evaluated. The residual stress of DSP was greater in SP(0.6+0.08) than SP(0.8+0.08) and appeared deeper in the depth direction. In addition, the hardness below the surface appeared larger. The fatigue limit of DSP increased 2.07 times and 1.95 times compared to non-SP. All ahml of the DSP specimen was determined at the depth (a). The compressive residual stress distribution affects ahml, and the ahml of SP(0.6+0.08), which has a large compressive residual stress and a high fatigue limit, appeared large. ahml of SP(0.6+0.08) introduced deeper than the residual stress of SP(0.8+0.08) is larger in the range of As=1.0-0.3. Since the residual stress in the thickness direction has a greater effect on ahml than the residual stress at the surface, it is necessary to introduce it more deeply. The relation of ahml, a25,50, and aNDI were evaluated in the point for safety and reliability.

An Influence of Intolerance of Uncertainty on Entrepreneurial Intention of College Students: Focused on Start-up Support System Perception (대학생의 불확실성에 대한 인내력 부족이 창업의지에 미치는 영향: 창업지원제도지각도를 매개로)

  • Ko, Sang Hee;Park, Woojin;Bae, Byung Yun
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.17 no.5
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    • pp.95-104
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    • 2022
  • This study aims to find out the influence of the intolerance of uncertainty on entrepreneurial intention by focusing on the start-up support system awareness. While most of existing studies focused on the positive psychological variables and individual environmental characteristics influencing on the entrepreneurial intention, this study has taken a look at the influence of the intolerance of uncertainty as the psychological variable to the entrepreneurial intention to negatively act on the entrepreneurial intention. As a result of the analysis, the intolerance of uncertainty under the control of entrepreneurship and gender is shown to have the negative (-) influence on the entrepreneurial intention and has high level of recognition on the start-up support system perception, and the start-up support system perception is confirmed to have positive (+) influence on the entrepreneurial intention. And, it also indicates that, with respect to the influence of the intolerance of uncertainty on the entrepreneurial intention, the start-up support system perception has the partial medium effect. Following this result of the study, it provides following indications: First the existing studies on the entrepreneurial intention had not covered the intolerance of uncertainty but it is confirmed as the psychological variable with negative influence on the entrepreneurial intention. Second, it is feasible for the preliminary start-up businesses may turn the fear on start-up failure into positive entrepreneurial intention with the start-up support system perception as the leading vehicle. And, third, based on the result, the government should enhance the start-up support system perception even more by seeking ways of efficient publicity to enable more preliminary start-up businesses to participate in diverse start-up support policies. Lastly, it discusses the limitations of this study as well as proposal for ensuing study plans.

Active Phytochemicals of Indian Spices Target Leading Proteins Involved in Breast Cancer: An in Silico Study

  • Ashok Kumar Krishnakumar;Jayanthi Malaiyandi;Pavatharani Muralidharan;Arvind Rehalia;Anami Ahuja;Vidhya Duraisamy;Usha Agrawal;Anjani Kumar Singh;Himanshu Narayan, Singh;Vishnu Swarup
    • Journal of the Korean Chemical Society
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    • v.68 no.3
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    • pp.151-159
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    • 2024
  • Indian spices are well known for their numerous health benefits, flavour, taste, and colour. Recent Advancements in chemical technology have led to better extraction and identification of bioactive molecules (phytochemicals) from spices. The therapeutic effects of spices against diabetes, cardiac problems, and various cancers has been well established. The present in silico study aims to investigate the binding affinity of 29 phytochemicals from 11 Indian spices with two prominent proteins, BCL3 and CXCL10 involved in invasiveness and bone metastasis of breast cancer. The three-dimensional structures of 29 phytochemicals were extracted from PubChem database. Protein Data Bank was used to retrieve the 3D structures of BCL3 and CXCL10 proteins. The drug-likeness and other properties of compounds were analysed by ADME and Lipinski rule of five (RO5). All computational simulations were carried out using Autodock 4.0 on Windows platform. The proteins were set to be rigid and compounds were kept free to rotate. In-silico study demonstrated a strong complex formation (positive binding constants and negative binding energy ΔG) between all phytochemicals and target proteins. However, piperine and sesamolin demonstrated high binding constants with BCL3 (50.681 × 103 mol-1, 137.76 × 103 mol-1) and CXCL10 (98.71 × 103 mol-1, 861.7 × 103 mol-1), respectively. The potential of these two phytochemicals as a drug candidate was highlighted by their binding energy of -6.5 kcal mol-1, -7.1 kcal mol-1 with BCL3 and -6.9 kcal mol-1, -8.2 kcal mol-1 with CXCL10, respectively coupled with their favourable drug likeliness and pharmacokinetics properties. These findings underscore the potential of piperine and sesamolin as drug candidates for inhibiting invasiveness and regulating breast cancer metastasis. However, further validation through in vitro and in vivo studies is necessary to confirm the in silico results and evaluate their clinical potential.

Taxonomic characterization of novel Hymenobacter sp. B2 isolated from a freshwater environment (민물환경에서 분리된 novel Hymenobacter sp. B2의 분류학적 특성연구)

  • Young-Min Bae
    • Journal of the Korean Applied Science and Technology
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    • v.40 no.4
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    • pp.881-889
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    • 2023
  • The genus Hymenobacter, type genus of the family Hymenobacteraceae and a member of the phylum Bacteroidota includes gram-negative and red-pigmented rods. Those bacteria have been isolated from various environments of the earth. I isolated a red-pigmented, gram-negative rod from a pond in the campus of the Changwon University, Changwon, Kyeongnam and designated this bacterium as strain B2. Strain B2 was further analyzed phylogenetically and biochemically, and concluded as a member of genus Hymenobacter. BLAST search of the 16S rRNA gene sequence of strain B2 showed its homology lower than 98.7% with those sequences of the other bacteria whose 16S rRNA gene sequences have been reported. Fatty acid composition of the strain B2 was analyzed and its major fatty acids are summed feature 3(C16:1 ω7c and/or C16:1 ω6c, 22.8%), iso-C15:0 (16.2%), anteiso-C15:0(12.9%), C16:1ω5c(12.4%) and summed feature 4 (iso-C17:1 I/anteiso-C17:1)(9.5%) showing significant differences in fatty acid compositions between strain B2 and the other known Hymenobacter species. DNA sequence of 16S rRNA gene of strain B2 was deposited in genbank under accession number OQ318247.