• The Korean Journal of Physiology
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• 제11권1호
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• pp.1-9
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• 1977

Action of anthraquinone on the sodium plus potassium activated ATPase activity in the rabbit red cell membrane has been investigated and the experiments were also designed to determine the mechanism of action of anthraquinone on the ATPase activity. The following results were obtained 1. The activity of the NaK ATPase from red cell membrane is inhibited by anthraquinone and the concentration of anthraquinone for maximal inhibition is about 5mM. 2. The ratio of inhibition of NaK ATPase by anthraquinone, with a giving concentration of sodium in the medium, is increased by raising the potassium concentration. 3. The ratio of inhibition of NaK ATPase by anthraquinone, with a given concentration of potassium in the medium, is increased by raising the sodium concentration. 4. The action of anthraquinone on the NaK ATPase activity is inhibited by calcium ions and the ratio of inhibition is increased by small amounts of calcium but almost constant by larger amounts. 5. The inhibitory action of anthraquinone on the NaK ATPase activity was not related to the amino group of lysine, the hydroxyl group of threonine or the imidazole group of histidine. 6. The inhibitory action of anthraquinone on the ATPase activity is due to sulfhydryl group or the carboxyl group of the enzyme of NaK ATPase.

• Journal of Microbiology and Biotechnology
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• 제19권12호
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• pp.1644-1649
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• 2009

This study investigates the buffering effects of calcium salts in kimchi on the total acidity, microbial population, and dextransucrase activity. Calcium chloride or calcium carbonate was added to dongchimi-kimchi, a watery radish kimchi, and the effects on various biochemical attributes were analyzed. The addition of 0.1% calcium chloride produced a milder decrease in the pH after 24 days of incubation, which allowed the lactic acid bacteria to survive longer than in the control. In particular, the heterofermentative Leuconostoc genus population was 10-fold higher than that in the control. When sucrose and maltose were also added along with the calcium salts, the dextransucrase activity in the kimchi was elevated and a higher concentration of isomaltooligosaccharides was synthesized when compared with the control. Calcium chloride was determined as a better activator compound of dextransucrase than calcium carbonate, probably because of its higher solubility. Therefore, the results of this study confirm the ability of the proposed approach to modulate the kimchi fermentation process and possibly enhance the quality of kimchi based on the addition of dietary calcium salts.

• 한국식품영양과학회지
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• 제35권7호
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• pp.860-865
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• 2006

본 연구는 주정과 구연산을 처리한 대멸분말과 함께 식이성 칼슘소재가 SD계 흰쥐의 칼슘대사에 미치는 영향을 조사하기 위하여 수행되었다. 실험식이는 대델분말의 칼슘함량을 고려하여 식이중의 칼슘함량이 0.1%가 되도록 semi-purified diet(AIN-diet, 1977)에 건조대별분말을 첨가한 대조군(C), 주정-구연산처 리군(EC), 주정-구연산+CPPS처리군(ECC), 젖산칼슘첨가군(CL) 및 인산칼슘침가군(CP)으로처리하여 5주동안 실험한 결과는 다음과 같다. 증체랑은 EC군이 ECC군과 일반적인 칼슘소재로 이용되는 젖산칼슘군(CL)과 인산칼슘군(CP)에 비해 유의하게 높았고(p<0.05), 식이효율(FER)은 차이가 없었다. 생체내외(in vitro 을 in vivo) 칼슘흡수율은 CPP를 처리한 ECC군이 각각 20.4%,28.4%로 실험군중 가장 높았다(p<0.05). 혈당치는 CL군(105.7 mg/dL)이 대조군(89.5 mg/dL)보다 유의하게 높았고 (p<0.05), TC농도는 EC군(75.1 mg/dL)이 CP군(65.6 mg/dL)보다 높았으며, TG농도는 CP군(33.5 mg/dL)이 통계적으로 가장 낮았다(p<0.05). ALP활성과 057농토는 실험군간 차이가 없이 CL군이 대조군보다 다소 높았다. 혈중 Ca농토는 칼슘흡수율이 가장 낮은 대조군(C)이 10.82 mg/dL로 유의하게 낮았고, EC군과 ECC군이 가장 높았다(p<0.05). 대퇴골무게는 CP군이 가장 낮았고(p<0.05),길이는ECC군이 가장 길었다(P<0.05). 골밀도는 CP군$(0.1116\;g/cm^2)$이 가장 낮았던 반면, ECC군$(0.1149\;g/cm^2)$이 가장 높았다. 이상의 결과에서 CPPs를 첨가한 ECC군이 생체내의 칼슘흡수율과 혈중 Ca농도 및 대퇴골의 길이와 밀도 등에 유의한 상승효과를 미친 것으로 나타났다. 향추 본 연구결과는 칼슘흡수율을 높이고 색택의 개선 및 관능이 향상된 기능성제품 개발의 기초자료로 활용될 수 있을 것으로 사료된다.

• 한국동물학회:학술대회논문집
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• 한국동물학회 1995년도 한국생물과학협회 학술발표대회
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• pp.293.2-293
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• 1995

No Abstract, See Full Text

• 공업화학
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• 제17권1호
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• pp.44-51
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• 2006

유동층 반응기에서 세 가지 석회석의 $CO_2$ 흡수능력에 미치는 반복횟수와 $SO_2$ 농도의 영향을 연구하였다. 측정된 $CO_2$ 흡수능력은 반복횟수가 증가하고 $SO_2$ 농도가 증가함에 따라 감소하였다. 한편 $SO_2$ 흡수능력은 반복횟수와 $SO_2$ 농도가 증가함에 따라 증가하였다. 총괄칼슘이용률은 반복횟수가 증가함에 따라 감소하였으나 총괄칼슘이용률에 대한 $SO_2$ 농도의 영향은 석회석의 종류에 따라 다른 경향을 나타내었다. Strassburg 석회석의 경우 총괄칼슘 이용률은 $SO_2$ 농도가 증가함에 따라 감소하는 반면, Luscar 및 단양 석회석의 경우에는 본 연구의 실험범위 내에서 $SO_2$ 농도에 무관한 경향을 나타내었다. 본 연구의 실험결과에 의하면 연소배가스 중 $SO_2$의 존재는 석회석의 $CO_2$ 흡수능력을 감소시키며 석회석의 황하반응 경향이 $CO_2$ 흡수능력에 영향을 미치는 것으로 나타났다.

• 산업기술연구
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• 제21권B호
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• pp.141-147
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• 2001

For the preparation of calcium carbonate particles from aqueous $Ca(OH)_2$ slurry, carbonation reaction of aqueous $Ca(OH)_2$ slurry was carried out by batch method the $CO_2$ into reactor filled with aqueous slurry of $Ca(OH)_2$. The concentration of $Ca(OH)_2$ varies from 1.00 to 7.00wt%, reactor temperature at 20 and $40^{\circ}C$, and reactor pressure from atmospheric pressure to $6.0kg_f/cm^2$. Crystal structure of calcium carbonate was of calcite, the particle size were about $0.05{\sim}2.0{\mu}m$, and the particle shape was cubic and spindle. When reactor temperature was higher, particle size of calcium carbonate was bigger and particle shape was varied, but reaction rate was increased. When reactor pressure was higher, particle size of calcium carbonate was smaller, particle shape was cubic, and reaction rate was increased.

• The Korean Journal of Physiology
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• 제26권2호
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• pp.123-128
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• 1992

The present study was undertaken to examine if endogenous nitric oxide is partly responsible for the high calcium induced vasorelaxation in vitro. Isolated porcine coronary arterial rings were suspended in the tissue chamber and their changes in isometric tension were recorded. KCI little affected the vascular tension in the calcium free media, but subsequent addition of cumulative doses of $CaCl_3$ from 1 to 40 mM caused a contraction followed by complete relaxation. The maximum tension was noted at the calcium concentration in the media of 5 mM, and then the tension progressively declined at 10-40 mM. The relaxation was slightly attenuated in the endothelium-denuded preparation. The relaxation was converted into a contraction by the addition of methylene blue. The relaxation response was not affected in the presence of indomethacin, but was significantly attenuated by $N^w-nitro-L-arginine$ methyl ester pretreatment. These results suggest that the calcium induced vasorelaxation is in part attributable to the release of endogenous nitric oxide.

• Clinical and Experimental Pediatrics
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• 제58권4호
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• pp.148-153
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• 2015

The calcium sensing receptor (CaSR) plays an important role in calcium homeostasis. Activating mutations of CaSR cause autosomal dominant hypocalcemia by affecting parathyroid hormone secretion in parathyroid gland and calcium resorption in kidney. They can also cause a type 5 Bartter syndrome by inhibiting the apical potassium channel in the thick ascending limb of the loop of Henle in the kidney. This study presents a patient who had autosomal dominant hypocalcemia with Bartter syndrome due to an activating mutation Y829C in the transmembrane domain of the CaSR. Symptoms of hypocalcemia occurred 12 days after birth and medication was started immediately. Medullary nephrocalcinosis and basal ganglia calcification were found at 7 years old and at 17 years old. Three hypercalcemic episodes occurred, one at 14 years old and two at 17 years old. The Bartter syndrome was not severe while the serum calcium concentration was controlled, but during hypercalcemic periods, the symptoms of Bartter syndrome were aggravated.

• Preventive Nutrition and Food Science
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• 제2권1호
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• pp.35-41
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• 1997

The pancreas is an important organ in the maintenance of zinc homeostasis. Endogenous zinc is con-tinuously secreted via pancreatic exocrine fluid or to a lesser extent in bile. Much of the endogenous secretion must be reabsorbed to sustain zinc homeostasis. The objective of this study was to estimate the relative size of the pancreatic/biliary zinc pool in comparision to the dietary zinc intake, and to study the effect of the phytate and calcium on the zinc homeostasis using a rat model. At the termination of the experiment, pan-creatic/biliary fluid was collected from the rats. Both radioactivity and total zinc were measured and the relative size of the pancreatic/biliary zinc pool was estimated. To determine the effect of phytate and calcium on zinc homeostsis, dietary zinc intake, the amount of zinc in pancreatic.biliary fluid and fecal zinc excretion were measured. The flow rate of pancreatic/biliary fluid, as corrected for tubing constriction, gives the corrected zinc concentration in the pancreatic/biliary fluid was 2.2 times higher than dietary zinc intake. To maintain zinc homeostasis, zinc absorption/reabsorption was very efficient in the current model; 76%, 88% of absorption/reabsorption for low calcium group and high calcium group 81% for phytate group and non-phytate group, respectively.

• 한국식품과학회지
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• 제29권3호
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• pp.576-580
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• 1997

배추를 절이는 과정에서 배추 lipoxygenase의 활성변화는 linoleic acid를 기질로 하여 용존산소 소비량의 변화로 효소활성을 측정하였다. 소금물에 배추를 침지한 경우 소금의 농도가 증가할수록, 절임시간이 길어질수록 효소의 실활 정도가 큰 것으로 나타났다. 13%의 소금물에서 5시간 절인 후 약 60%의 효소활성이 감소하였다. 한편 calcium chloride의 영향을 살펴보기 위하여 절임시 0.7% calcium chloride를 첨가한 결과 calcium chloride를 첨가한 것이 calcium chloride를 첨가하지 않은 것 보다 효소의 실활정도가 $10{\sim}15%$ 적은 것으로 나타났다. 효소 저해제로 마늘 추출물을 사용한 결과 생배추에 첨가한 경우는 약 40%, 13%의 소금물에 절인 후의 배추의 경우는 약 20%의 잔존활성을 보여 주었다.