• Title/Summary/Keyword: burns

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Recovery of Phosphorus in Animal Wastewater by Struvite Forming (Struvite 형성에 의한 축산폐수의 인 회수기술 개발)

  • Oh, I.H.;Lee, J.H.;Choi, B.H.;Myung, N.S.;Burns, R.T.
    • Journal of Biosystems Engineering
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    • v.31 no.1 s.114
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    • pp.46-51
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    • 2006
  • This study was carried out to recover phosphorus in animal wastewater using a magnesium source. $MgCl_2$, as a magnesium source, was shown a SP (soluble phosphorus) recovery rate of 98% in both the aeration and the NaOH tests to adjust pH around 8.5. In case of MgO, the recovery rate of SP were 88% with the aeration and 58% with the NaOH. In case of ammonia nitrogen recovery, $MgCl_2$ was shown the recovery rate of 17% with aeration and 18% with NaOH. MgO was shown the ammonia recovery rate of 18% with aeration and 11% with NaOH. At low temperature of $6-8^{\circ}C$ with the animal wastewater from piglet stall, the recovery rate of SP was shown 95% with NaOH and 92% with aeration using $MgCl_2$. The recovery rate of ammonia nitrogen was shown 9% with NaOH and 12% with aeration, respectively. It was observed that the pH can be raised by aeration. The reaction was completed within 5 minutes and the struvite cristal structure was formed and could be observed with an electronic microscope.

The Role of Corticotropin-Releasing Factor and Urocortin in Brain Mechanisms Controlling Feed Intake of Sheep

  • Sunagawa, K.;Weisiger, R.S.;McKinley, M.J.;Purcell, B.S.;Thomson, C.;Burns, P.L.
    • Asian-Australasian Journal of Animal Sciences
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    • v.13 no.11
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    • pp.1529-1535
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    • 2000
  • The aim of the present study was to determine whether brain corticotropin-releasing factor (CRF) and a new peptide, urocortin (UCN) have a direct action in brain mechanisms controlling feed, water and salt intake in sheep. We gave a continuous intracerebroventricular (ICV) infusion of the peptide at a small dose of $5{\mu}g/0.2ml/hr$ for 98.5 hrs from day 1 to day 5 in sheep not exposed to stress. Feed and water intake during ICV infusion of CRF or UCN decreased significantly compared to those during artificial cerebrospinal fluid (CSF) infusion. NaCl intake during infusion of CRF or UCN was the same as that during CSF infusion. Mean carotid arterial blood pressure (MAP) and heart rate during ICV infusion of CRF or UCN were not significantly different from that during CSF infusion. On the other hand, the plasma glucose concentration during ICV infusion of CRF or UCN tended to be higher than that during CSF infusion. These observations indicate that decreased feed intake induced by CRF and UCN infusion is not mediated by the activation of both the pituitary-adrenal axis and the sympathetic nervous system. The results suggested that brain CRF and UCN act directly in brain mechanisms controlling ingestive behavior to decrease feed and water intake, but do not alter salt intake in sheep.

Growth Period Effects on the Protective Properties of Aloe vera Against t-BHP-Induced Oxidative Stress in Chang Cells

  • Hwang, Jin-Woo;Kim, Eun-Kyung;Kim, Yon-Suk;Lee, Jae Woong;Lee, Jeong-Jun;Pyo, Han-Jong;Moon, Sang-Ho;Jeon, Byong-Tae;Park, Pyo-Jam
    • Journal of Microbiology and Biotechnology
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    • v.25 no.12
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    • pp.2072-2081
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    • 2015
  • Aloe vera has been used in traditional medicine for the therapy of a variety of disorders, such as wounds and burns. However, few studies have examined the antioxidant capacities of A. vera plants during different growth periods. In order to investigate the effects of growth on antioxidant activity, A. vera was prepared from 2-, 4-, 6-, 8-, and 12-month-old aloe. The extracts from 6-month-old A. vera showed the highest contents of flavonoids (9.750 mg catechin equivalent/g extract) and polyphenols (23.375 mg gallic acid equivalent/g extract) and the highest ferric reducing antioxidant power (0.047 mM ferrous sulfate equivalent/mg extract). The extract from 6-month-old A. vera exhibited the highest free radical scavenging potential, and the lowest IC50 values were found for 2,2-diphenyl-1-picrylhydrazyl (0.26 mg/ml) and alkyl radicals (0.50 mg/ml). In addition, the extract from 6-month-old A. vera showed the greatest effects on cell viability in normal liver cells. Based on these findings, the extract from 6-month-old A. vera was examined further in order to determine its protective potential against tert-butyl hydroperoxide (t-BHP)-induced oxidative stress. The extract from 6-month-old A. vera at a concentration of 0.25 mg/ml showed the highest protective activity against t-BHP-induced reactive oxygen species production. These findings suggested that harvesting regimens were critical in the regulation of effects of the bioactive potential of A. vera on antioxidant activity.

Sonchus asper extract inhibits LPS-induced oxidative stress and pro-inflammatory cytokine production in RAW264.7 macrophages

  • Wang, Lan;Xu, Ming Lu;Liu, Jie;Wang, You;Hu, Jian He;Wang, Myeong-Hyeon
    • Nutrition Research and Practice
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    • v.9 no.6
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    • pp.579-585
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    • 2015
  • BACKGROUND/OBJECTIVES: Sonchus asper is used extensively as an herbal anti-inflammatory for treatment of bronchitis, asthma, wounds, burns, and cough; however, further investigation is needed in order to understand the underlying mechanism. To determine its mechanism of action, we examined the effects of an ethyl acetate fraction (EAF) of S. asper on nitric oxide (NO) production and prostaglandin-E2 levels in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. MATERIALS/METHODS: An in vitro culture of RAW264.7 macrophages was treated with LPS to induce inflammation. RESULTS: Treatment with EAF resulted in significant suppression of oxidative stress in RAW264.7 macrophages as demonstrated by increased endogenous superoxide dismutase (SOD) activity and intracellular glutathione levels, decreased generation of reactive oxygen species and lipid peroxidation, and restoration of the mitochondrial membrane potential. To confirm its anti-inflammatory effects, analysis of expression of inducible NO synthase, cyclooxygenase-2, tumor necrosis factor-${\alpha}$, and the anti-inflammatory cytokines IL-$1{\beta}$ and IL-6 was performed using semi-quantitative RT-PCR. EAF treatment resulted in significantly reduced dose-dependent expression of all of these factors, and enhanced expression of the antioxidants MnSOD and heme oxygenase-1. In addition, HPLC fingerprint results suggest that rutin, caffeic acid, and quercetin may be the active ingredients in EAF. CONCLUSIONS: Taken together, findings of this study imply that the anti-inflammatory effect of EAF on LPS-stimulated RAW264.7 cells is mediated by suppression of oxidative stress.

Analysis of Radiative Heat Transfer and Thermal Stress in Flaring System of FPSO (FPSO 소각탑의 복사열전달 및 열응력 해석에 관한 연구)

  • Jang-Hyun Lee;Jong-Gye Shin;In-Sik Nho
    • Journal of the Society of Naval Architects of Korea
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    • v.39 no.1
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    • pp.61-72
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    • 2002
  • The flaring system of FPSO burns out the byproduct natural gas. The thermal loading due to radiative heat of flaring gas leads to undesirable thermal-stresses on itself. Nowadays it needs to understand the amount of thermal loading of flaring system since the requirement for the safety of the flaring system. However, few studies have been performed on the thermal environment and radiative heat flux on the FPSO flaring system. Present study suggests a procedure to model the thermal environment and a FEA process to analyze the temperature distribution and thermal stresses of FPSO flaring system. In order to get the temperature distribution, the radiative heat conditions and convective heat conditions are included in the heat transfer analysis. By making the use of temperature obtained through heat transfer analysis, the thermal stress analyses are performed. The results of the present study can be used to design the flaring system and determine the heat shield in the flaring system.

Scar Status, Depression, Sleep, and Health Related Quality of Life Following Severe Burn Injury: A Cross-sectional Descriptive Study

  • Oh, Hyunjin;Kim, Kyungja;Seo, Cheonghoon;Kim, Dohern;Lee, Boung Chul;Boo, Sunjoo
    • Journal of Home Health Care Nursing
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    • v.26 no.3
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    • pp.341-348
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    • 2019
  • Purpose: Severe burn injuries require long periods of hospitalization and treatment, which results in various physical and psychological issues. The main purpose of this study was to identify burn characteristics and psychological problems that influence Health Related Quality of Life (HRQoL) after discharge. Methods: A cross-sectional descriptive study using mobile/web or paper-based survey methods was conducted from a major burn center. A total of 145 patients completed the scar assessment, quality of life, sleep disorders, and depression scales. Results: The overall mean HRQoL and scar status scores were 2.28 out of 5 and 34.45 out of 60 points, respectively. Participants with higher burn degree, joint involvement, and emotional distress reported significantly lower HRQoL and scar status. Participants with depression and sleep problems also had lower HRQoL. Significant predictors of HRQoL included burn range, scar status, depression, and sleep issues. Conclusion: The results show that patients with severe burn injury experience high levels of physical and psychological problems. Patients with severe burn injury and psychological problems such as depression and sleep are likely to experience a reduced HRQoL. Psychological management and intervention in home care setting may improve HRQoL of burn patients.

Soft Tissue Reconstruction of Complete Circumferential Defects of the Upper Extremity

  • Ng, Zhi Yang;Tan, Shaun Shi Yan;Lellouch, Alexandre Gaston;Cetrulo, Curtis Lisante Jr;Chim, Harvey Wei Ming
    • Archives of Plastic Surgery
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    • v.44 no.2
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    • pp.117-123
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    • 2017
  • Background Upper extremity soft tissue defects with complete circumferential involvement are not common. Coupled with the unique anatomy of the upper extremity, the underlying etiology of such circumferential soft tissue defects represent additional reconstructive challenges that require treatment to be tailored to both the patient and the wound. The aim of this study is to review the various options for soft tissue reconstruction of complete circumferential defects in the upper extremity. Methods A literature review of PubMed and MEDLINE up to December 2016 was performed. The current study focuses on forearm and arm defects from the level at or proximal to the wrist and were assessed based on Tajima's classification (J Trauma 1974). Data reviewed for analysis included patient demographics, causality, defect size, reconstructive technique(s) employed, and postoperative follow-up and functional outcomes (when available). Results In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, 14 unique articles were identified for a total of 50 patients (mean=28.1 years). Underlying etiologies varied from extensive thermal or electrical burns to high impact trauma leading to degloving or avulsion, crush injuries, or even occur iatrogenically after tumor extirpation or extensive debridement. Treatment options ranged from the application of negative pressure wound dressings to the opposite end of the spectrum in hand transplantation. Conclusions With the evolution of reconstructive techniques over time, the extent of functional and aesthetic rehabilitation of these complex upper extremity injuries has also improved. The proposed management algorithm comprehensively addresses the inherent challenges associated with these complex cases.

Case Study on Safety Situation and Awareness through Risk Assessment of Hospital Foodservice Kitchen Area (병원급식 조리구역별 위험도 평가를 통한 안전사고 실태 및 안전인식에 관한 사례연구)

  • Kim, Hye-Jin;Hong, Jeong-Im;Heo, Gyu-Jin;Park, Joo-Yeon
    • Journal of the Korean Dietetic Association
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    • v.22 no.1
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    • pp.13-25
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    • 2016
  • This study was carried out to provide a basis for the development of a safety manual for kitchen accident prevention by identifying the safety situation and awareness through risk assessment of kitchen areas. The study was conducted in two phases. First, kitchen accidents and area risk assessment were investigated from February 2014 to September 2014, after which safety awareness of hospital foodservice employees was assessed in a survey. The results of this study were as followes. All of the respondents were women. The evaluation point of kitchen area risk assessment was reduced by 14%. After improvement, an initial score of 108 points decreased to 93 points. The number of accidents was also reduced by 78%; 14 accidents were decreased to three. The most common area of accidents was the kitchen area (58.8%), and burns was the most common accident (35.3%). Most of the employees deemed "enough staff" as the most major factor for good foodservice. "High indoor temperature and poor ventilation in the kitchen area" was chosen as the most common problem in the foodservice workplace. Taken together, our study quantitatively evaluated safety issues in hospital foodservice kitchen areas and provides a basis for the development of a safety manual for kitchen accident prevention.

The Effects of Topical Agent (Kelo-Cote or Contractubex) Massage on the Thickness of Post-Burn Scar Tissue Formed in Rats

  • Ko, Won Jin;Na, Young Cheon;Suh, Bum Sin;Kim, Hyeon A;Heo, Woo Hoe;Choi, Gum Ha;Lee, Seo Ul
    • Archives of Plastic Surgery
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    • v.40 no.6
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    • pp.697-704
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    • 2013
  • Background We conducted an experimental study to compare the effect of massage using topical agents (Kelo-cote or Contractubex) on scar formation by massaging the healed burn wound on the dorsal area of Sprague-Dawley (SD) rats. Methods Four areas of second degree contact burn were made on the dorsal area of each of 15 SD rats, using a soldering iron 15 mm in diameter. After gross epithelialization in the defect, 15 SD rats were randomly divided into four groups: the Kelo-cote group, Contractubex group, Vaseline group, and control group. Rats in three of the groups (all but the Control group) were massaged twice per day for 5 minutes each day, while those in the Control group were left unattended. For histologic analysis, we performed a biopsy and evaluated the thickness of scar tissue. Results In the Kelo-cote and Contractubex groups, scar tissue thicknesses showed a significant decrease, compared with the Vaseline and control groups. However, no significant differences were observed between the Kelo-cote and Contractubex groups. In the Vaseline group, scar tissue thicknesses showed a significant decrease, compared with the control groups. Conclusions The findings of this study suggest that massage using a topical agent is helpful in the prevention of scar formation and that massage only with lubricant (no use of a topical agent) also has a considerable effect, although not as much as the use of a topical agent. Thus, we recommend massage with a topical agent on the post-burn scar as an effective method for decreasing the scar thickness.

Effects of Topical Tamoxifen on Wound Healing of Burned Skin in Rats

  • Mehrvarz, Shaban;Ebrahimi, Ali;Sahraei, Hedayat;Bagheri, Mohammad Hasan;Fazili, Sima;Manoochehry, Shahram;Rasouli, Hamid Reza
    • Archives of Plastic Surgery
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    • v.44 no.5
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    • pp.378-383
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    • 2017
  • Background This study aimed to assess the effects of the topical application of tamoxifen on wound healing of burned skin in Wistar rats by evaluating 3 healing characteristics: fibrotic tissue thickness (FTT), scar surface area (SSA), and angiogenesis in the healed scar tissue. Methods Eighteen male Wistar rats were used in this study. A third-degree burn wound was made on the shaved animals' back, measuring $2{\times}2{\times}2cm$. In the first group, a 2% tamoxifen ointment was applied to the wound twice daily for 8 weeks. The second group received a placebo ointment during the same period. The third group did not receive any treatment and served as the control group. Results The median (interquartile range=[Q1, Q3]) FTT was 1.35 (1.15, 1.62) mm, 1.00 (0.95, 1.02) mm, and 1.25 (0.8, 1.5) mm in the control, tamoxifen, and placebo groups, respectively (P=0.069). However, the FTT in the tamoxifen group was less than in the placebo and control groups. The median angiogenesis was 3.5 (3.00, 6.25), 8.00 (6.75, 9.25), and 7.00 (5.50, 8.25) vessels per high-power field for the control, tamoxifen, and placebo groups, respectively (P=0.067). However, the median angiogenesis was higher in the tamoxifen group than in the control group. No significant difference was observed in the mean SSA between the tamoxifen group and the control group (P=0.990). Conclusions Local application of tamoxifen increased angiogenesis and decreased the FTT, with no change in the SSA in burned skin areas. These effects are expected to expedite the wound healing process, reducing contracture and preventing hypertrophic scar and keloid formation.