• Journal of Families and Better Life
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• v.26 no.5
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• pp.91-107
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• 2008

This study investigated the isolation hypothesis and the buffer hypothesis of Demand-Control-Support model in relation to activity satisfaction and psychological well-being. The subjects were 300 elderly women participating in productive activity for example paid work, voluntary activity, and grancdhildren care. This research tested four hypotheses concerning the DCS model. Is there support for the isolation hypothesis, such that the lowest level of activity satisfaction is experienced by the elderly women working in an isolation situation(high demand-low control-low support)? Is there support for the isolation hypothesis, such that the lowest level of psychological well-being is experienced by the elderly women working in an isolation situation(high demand-low control-low support)? Is there support for the buffer hypothesis, i. e. interaction between demand, control, and support, indicating a buffering effect of support on the negative impact of high strain on activity satisfaction? Is there support for the buffer hypothesis, i. e. interaction between demand, control, and support, indicating a buffering effect of support on the negative impact of high strain on psychological well-being? Major results of this study were as follows. and were supported. Activity satisfaction and psychological well-being of the elderly women in isolation situation was the lowest among the sample. was supported that family support level buffered the negative impact of high strain on activity satisfaction. But was not supported. Only main effect of demand level was showed on psychological well-being.

• Journal of Korea Entertainment Industry Association
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• v.13 no.2
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• pp.79-91
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• 2019

In the entertainment industry, risk management is crucial for securing competitiveness due to the risk of investment. The competitiveness of contents is reinforced when external factors such as industrial environment and internal factors centering on involving mechanism are simultaneously provided. The involving mechanism is a form of cognitive response behavior of the audience and occurs through signal processing of the brain when watching the image contents. The signal processing of the brain related to the contents watching is mainly performed in the working memory area, and in the case of the captivating movie, the information other than the contents transmitted to the audience is blocked to generate a temporary dissociation state. A dissociation state similar to a symptom such as hypnosis or amnesia occurs when the audience's level of involving is high. On the other hand, contents information in which the audience is concentrating his attention is used intensively for constructing future thinking through an episodic buffer while the inflow of external information is relatively blocked or delayed. The spectator's future thinking configuration takes the form of a hypothesis-forming activity and is based on the predictability of the brain. When these hypothesized behaviors correspond to the problem solving simulation of story and predictability which is an evolutionary function of the brain, the audience' s brain is involved in the contents at a high level. In order for the act to be effective, the factors such as the background of the hypothesis, the subject of the hypothesis, the internal information of the person, the type and position and quantity of the hypothesis information, and the hypothesis relevance and type of information are important. Based on these factors, analysis of the Kim Eun Sook Drama 'Goblin' shows that the above elements are operated in a very organic and meaningful way.

• Journal of the Korea Institute of Military Science and Technology
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• v.17 no.6
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• pp.725-732
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• 2014

The silencer for the medium caliber gun was studied to reduce the propagation of gun-generated noise from the firing test range to the community. Three types of silencer were made to compare the reduction of sound pressure level and the effect of chamber volume and the exit angle to the reduction of sound pressure was considered. The structural analysis and measurement of pressure in the silencer showed that the structure is safe in terms of strength. The increase of recoil force to buffer must be considered in the development of silencer. The hypothesis test on the muzzle velocity for the existence of silencer showed that there are no difference at the significance level of 0.05.

• Science of Emotion and Sensibility
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• v.20 no.2
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• pp.45-58
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• 2017

The present study tested a hypothesis that mood awareness and emotional expressivity would attenuate the association between academic stress and adjustment. In support of the hypothesis, the present research showed that emotional expressivity moderated the association between academic stress and adjustment among college students. That is, the association was attenuated by emotional expressivity when academic stress was high more than when academic stress was low. Curiously, we also identified an interesting diversion between two factors of mood awareness. Specifically, mood monitoring moderated the negative association between academic stress and adjustment, whereas mood labeling did not. That is, mood monitoring was particularly effective when academic stress was high, but mood labeling showed substantial benefits regardless of the level of academic stress. Overall, the present results suggest that mood awareness (in particular, mood labeling) and emotional expressivity serve as cognitive and behavioral protective factors that can buffer academic stress among college students.

• Restorative Dentistry and Endodontics
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• v.24 no.1
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• pp.180-186
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• 1999

Eugenol has been reported to reduce odontogenic pain and is known to have a structure similar to capsaicin, a potent stimulant of certain nociceptors. We have hypothesized that the analgesic effect of eugenol may be due, in part, to inhibition of capsaicin-sensitive nociceptors. To test this hypothesis, we evaluate whether eugenol inhibits capsaicin-sensitive release of immunoreactive calcitonin generated peptide(iCGRP) from bovine dental pulp. Freshly extracted bovine incisors were transported to the lab. on ice, Spilitted and pulp tissue was removed. The tissue was chopped into 200${\mu}m$ slices. Dental pulp was superfused(340 ${\mu}l/min$) in vitro with oxygenated Kreb's buffer. Eugenol and vehicle(0.02% 2-hydroxyl-${\beta}$-cyclodextrin) were administered prior to stimulation of pulp with capsaicin and iCGRP was measured by RIA. The results were as follows: 1. Administration of eugenol has no effect on basal release of iCGRP. 2. In the vehicle treated group, capsaicin evoked a 2.5-fold increase over basal iCGRP levels. 3. Administration of eugenol(600 ${\mu}M$) reduced capsaicin evoked release of iCGRP by more than 40%(153.4${\pm}$41.1% vs 258.9${\pm}$21.7%). 4. 2-hydroxylpropyl-${\beta}$-cyclodextrin of less than 0.02% is found to be an effective vehicle to dissolve eugenol without evoking iCGRP release from dental bovine pulp. These data indicate that eugenol inhibits pulpal capsaicin-sensitive fibers and suggest that intracanal medicament of eugenol may relieve pain, in part, by this mechanism.

• Journal of the Korean Home Economics Association
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• v.43 no.8 s.210
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• pp.55-68
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• 2005

The purpose of this study is to examine the effects of negative life events on mental health and to explore possible main and moderating effects of spousal support on mental health with a focus on gender differences. The data for this study were taken from a nationwide random sample of 1,504 married men and women ranging in age from 30 to 59 through structured questionnaires. The data were analyzed using the SPSS WIN program which was used to calculate frequency, mean, 1-test, multiple regressions. The main results were as follows: First, by examining mental health of Korean men and women, women were more likely than men to experience higher levels of depression. Second, there was no gender difference in the sum of experience of negative life events, therefore the date of this study did not support the differential exposure hypothesis. In addition, men perceived more support from their spouses than women. Third, results show that especially the event concerning with job/financial problems has negative impacts on mental health of both men and women, and vulnerability to undesirable life events was not found. Fourth, spousal support is associated with better mental health regardless of gender, and it reduces the harmful effects of life events concerning with job/financial area for both men and women. Also, spousal support reduces the magnitude of the harmful effects of life events concerning with health of men. This study focused on the impact of negative life events and the couple process. It was possible to explore the strength of social support provided from spouse of most importance to the individuals. These results affirm the importance of supportive relationships between couples as a buffer, mitigating harmful effects of negative life events on mental health.

• Molecules and Cells
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• v.37 no.5
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• pp.412-417
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• 2014

It has been reported that exogenously introduced micro-RNA (exo-miRNA) competes with endogenously expressed miRNAs (endo-miRNAs) in human cells, resulting in a detectable upregulation of mRNAs with endo-miRNA target sites (TSs). However, the detailed mechanisms of the competition between exo- and endo-miRNAs remain uninvestigated. In this study, using 74 microarrays that monitored the whole-transcriptome response after introducing miRNAs or siRNAs into HeLa cells, we systematically examined the derepression of mRNAs with exo- and/or endo-miRNA TSs. We quantitatively assessed the effect of the number of endo-miRNA TSs on the degree of mRNA derepression. As a result, we observed that the number of endo-miRNA TSs was significantly associated with the degree of derepression, supporting that the derepression resulted from the competition between exo- and endo-miRNAs. However, when we examined whether the site proficiency of exo-miRNA TSs could also influence mRNA derepression, to our surprise, we discovered a strong positive correlation. Our analysis indicates that site proficiencies of both exo- and endo-miRNA TSs are important determinants for the degree of mRNA derepression, implying that the derepression of mRNAs in response to exo-miRNA is more complex than that currently perceived. Our observations may lead to a more complete understanding of the detailed mechanisms of the competition between exo- and endo-miRNAs and to a more accurate prediction of miRNA targets. Our analysis also suggests an interesting hypothesis that long 3'-UTRs may function as molecular buffer against gene expression regulation by individual miRNAs.

• The Plant Pathology Journal
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• v.24 no.3
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• pp.296-304
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• 2008

The transient and rapid expression system of a foreign protein in planta is a very useful technique in biotechnology application. We have investigated optimum condition of Agrobacterium-infiltration technique in which expression level of foreign proteins were maximized without detrimental effects on plants using GFP and Cucumber mosaic virus 2b protein, which is known as an enhancer of gene expression and a suppressor of post-transcriptional gene silencing(PTGS). The optimum expression level of both RNA and protein of GFP with minimum leaf impairment was obtained at $OD_{600}$=0.2 of Agrobactrium inocula. The steady-state levels of GFP RNA and protein generally peaked at 3 and 7 days post-infiltration(dpi), respectively. In the presence of 2b, both the magnitude and duration of GFP expression was highly increased and we could detect GFP level until 17 dpi. On the other hands, the 2b-mediated higher accumulation of foreign proteins resulted in the repression of normal leaf growth, possibly due to the limitation of supply of energy or materials required for growth maintenance. Using this Agrobacterium-infiltration system with 2b and GFP, we tested a hypothesis for the threshold model of PTGS initiation. Four GFP transgenic lines of N. benthamiana, which shows different expression level of GFP were tested to determine the threshold level for PTGS initiation. Agrobacterium-infiltration of GFP into those GFP-transgenic plants resulted in the co-silencing of the transgenic GFP. It was found that very low concentration of Agrobacterium with GFP and GFP+2b($OD_{600}$=0.002-0.02) which could not phenotypically induce an additive GFP expression, was enough to trigger PTGS pathway in all GFP transgenic plants. This strongly indicates that each GFP-transgenic plant should be expressing the transgenic GFP at its own pre-determined level and there was no buffer zone of additive GFP-expression to the threshold. In other words, the PTGS seems to be immediately activated as a self-defensive mechanism if an internal balance of gene expression is broken.

• Journal of the Korean Association of Geographic Information Studies
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• v.14 no.4
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• pp.221-237
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• 2011

This study aims to investigate the environmental equity of the accessibility to urban neighborhood parks in the city of Daegu. The spatial distribution of urban neighborhood parks was explored by spatial statistics and the spatial accessibility to them was then evaluated by both minimum distance and coverage approaches. Descriptive and inferential statistics such as proximity ratio, Mann Whitney U test, and logistic regression were used for comparing the socioeconomic characteristics over different accessibilities to the neighborhood parks and then testing the distributional inequity hypothesis. The results from the minimum distance method indicated that Dalseo-gu had the best accessibility to the neighborhood parks while Dong-gu had the worst accessibility. It was apparent with the coverage method that Dalseo-gu had the best accessibility whereas Dong-gu and Nam-gu had the worst accessibility to the neighborhood parks at 500m and 1,000m buffer distances. There existed the spatial pattern of environmental inequity in old towns with respect to population density and the percentage of people under the age of 18. The spatial pattern of environmental inequity in new towns was explored on the basis of the percentage of people over the age of 65, the percentage of people below the poverty level, and the percentage of free of charge rental housing. These results were closely related to the development process of urban parks in Daegu stimulated by the quantitative urban park policy, urban development process, and residential location pattern such as permanent rental housing and free of charge rental housing. This study further extends the existing research topics of environmental justice related to the distributional inequity of environmental disamenities and hazards by focusing on environmental amenities such as urban neighborhood parks. The results from this study can be used in making the decisions for urban park management and setting up urban park policy with considering the social geography of Daegu.

• Journal of Chest Surgery
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• v.29 no.2
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• pp.199-207
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• 1996

Ischemic myocardial damage is inevitable to cardiac surgery. Myocardial damage after initiation of reperfusion through the coronary arteries is one of the most important determinants of a successful surgery. Adenosine is a potent vasodilator, and is also known to induce rapid cardioplegic arrest by its property of antagonizing cardiac calcium channels and activating the potassium channel. Thus, we initiated this study with adenosine to improve postischemic recovery in the isolated rat heart. We tested the hypothesis that adenosine could be more effective than potassium in inducing rapid cardiac arrest and enhancing postischemlc hemodynamic recovery. Isolated rat hearts, connected to the Langendorff appratus, were perfused with Krebs-Henseleit buffer and all hearts were subjected to arrest for 60 minutes. Three groups of hearts were studied according to the composition of cardioplegic solutions : Group A (n=10), adenosine 10mmo1/L+potassium free modified St. Thomas cardioplegia : Group B (n=10), adenosine 400mo1/L+S1. Thomas cardioplegia:Group C(control, n=10), St. Thomas cardioplegia. Adenosine-treated groups (group A & B) resulted in more rapid cardiac arrest than control group (C) (p< 0.01). There was greater improvement in recovery of coronary blood flow at 20 and 30 minutes of reperfusion in group A and at 20 minutes in group B when compared with control group(p<0.01). Recovery of systolic blood pressure at 10 minutes after reperfusion in group A and B was significantly superior to that in group C (p<0.01). Recovery of dp/dt at 10 minute after reperfusion in group A was also significantly superior to group C (p<0.05). Group A and B showed better recovery rates than control group in aortic blood flow, cardiac output, and heart rate, but there were no statistical differences. CPK levels of coronary flow in group A were significantly low (p< 0.01). We concluded that adenosine-enriched cardioplegic solutions have better effects on rapid cardiac arrest and postischemic recovery when compared with potassium cardioplegia.